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Extraabdominal Fibromatosis

MedGen UID:
266160
•Concept ID:
C1275420
•
Neoplastic Process
Synonyms: Extra-abdominal desmoid tumor; Extra-abdominal fibromatosis; Extraabdominal Desmoid; Extraabdominal Desmoid Tumor
SNOMED CT: Extra-abdominal fibromatosis (400129003); Extra-abdominal desmoid tumor (400129003)

Definition

An insidious poorly circumscribed neoplasm arising from the soft tissues outside the abdomen. It is characterized by the presence of elongated spindle-shaped fibroblasts, vascular collagenous stroma formation, and an infiltrative growth pattern. [from NCI]

Professional guidelines

PubMed

Desmoid Tumors: Current Perspective and Treatment.
Mangla A, Agarwal N, Schwartz G
Curr Treat Options Oncol 2024 Feb;25(2):161-175. Epub 2024 Jan 25 doi: 10.1007/s11864-024-01177-5. PMID: 38270798Free PMC Article
Role of Imaging in Management of Desmoid-type Fibromatosis: A Primer for Radiologists.
Braschi-Amirfarzan M, Keraliya AR, Krajewski KM, Tirumani SH, Shinagare AB, Hornick JL, Baldini EH, George S, Ramaiya NH, Jagannathan JP
Radiographics 2016 May-Jun;36(3):767-82. doi: 10.1148/rg.2016150153. PMID: 27163593
Extra-abdominal desmoid fibromatosis: A review of management, current guidance and unanswered questions.
Eastley N, McCulloch T, Esler C, Hennig I, Fairbairn J, Gronchi A, Ashford R
Eur J Surg Oncol 2016 Jul;42(7):1071-83. Epub 2016 Feb 19 doi: 10.1016/j.ejso.2016.02.012. PMID: 26965303

Recent clinical studies

Etiology

Surgical outcomes following resection for sporadic abdominal wall fibromatosis.
Wilkinson MJ, Chan KE, Hayes AJ, Strauss DC
Ann Surg Oncol 2014 Jul;21(7):2144-9. Epub 2014 Mar 7 doi: 10.1245/s10434-014-3618-5. PMID: 24604586
Aggressive fibromatosis from infancy to adolescence.
Spiegel DA, Dormans JP, Meyer JS, Himelstein B, Mathur S, Asada N, Womer RB
J Pediatr Orthop 1999 Nov-Dec;19(6):776-84. PMID: 10573349
99mTc(V)-DMSA and 67Ga-citrate images in a patient with recurrent extraabdominal fibromatosis.
Ohta H, Komibuchi T, Tomihara M, Watanabe H, Fujikawa S, Shintaku M
Ann Nucl Med 1998 Aug;12(4):221-3. doi: 10.1007/BF03164850. PMID: 9795710

Diagnosis

Fibromatosis of the breast mimicking an abscess: case report of unusual sonographic features.
Lee SM, Lee JY, Lee BH, Kim SY, Joo M, Kim JI
Clin Imaging 2015 Jul-Aug;39(4):685-8. Epub 2015 Mar 14 doi: 10.1016/j.clinimag.2015.03.002. PMID: 25804801
Surgical outcomes following resection for sporadic abdominal wall fibromatosis.
Wilkinson MJ, Chan KE, Hayes AJ, Strauss DC
Ann Surg Oncol 2014 Jul;21(7):2144-9. Epub 2014 Mar 7 doi: 10.1245/s10434-014-3618-5. PMID: 24604586
Primary desmoid tumor (extraabdominal fibromatosis) of the breast.
Erguvan-Dogan B, Dempsey PJ, Ayyar G, Gilcrease MZ
AJR Am J Roentgenol 2005 Aug;185(2):488-9. doi: 10.2214/ajr.185.2.01850488. PMID: 16037525
Aggressive fibromatosis from infancy to adolescence.
Spiegel DA, Dormans JP, Meyer JS, Himelstein B, Mathur S, Asada N, Womer RB
J Pediatr Orthop 1999 Nov-Dec;19(6):776-84. PMID: 10573349
Desmoplastic fibroma of the bone. A report of two patients, review of the literature, and therapeutic implications.
Böhm P, Kröber S, Greschniok A, Laniado M, Kaiserling E
Cancer 1996 Sep 1;78(5):1011-23. doi: 10.1002/(SICI)1097-0142(19960901)78:5<1011::AID-CNCR11>3.0.CO;2-5. PMID: 8780539

Therapy

Surgical outcomes following resection for sporadic abdominal wall fibromatosis.
Wilkinson MJ, Chan KE, Hayes AJ, Strauss DC
Ann Surg Oncol 2014 Jul;21(7):2144-9. Epub 2014 Mar 7 doi: 10.1245/s10434-014-3618-5. PMID: 24604586

Prognosis

Surgical outcomes following resection for sporadic abdominal wall fibromatosis.
Wilkinson MJ, Chan KE, Hayes AJ, Strauss DC
Ann Surg Oncol 2014 Jul;21(7):2144-9. Epub 2014 Mar 7 doi: 10.1245/s10434-014-3618-5. PMID: 24604586
Aggressive fibromatosis from infancy to adolescence.
Spiegel DA, Dormans JP, Meyer JS, Himelstein B, Mathur S, Asada N, Womer RB
J Pediatr Orthop 1999 Nov-Dec;19(6):776-84. PMID: 10573349
99mTc(V)-DMSA and 67Ga-citrate images in a patient with recurrent extraabdominal fibromatosis.
Ohta H, Komibuchi T, Tomihara M, Watanabe H, Fujikawa S, Shintaku M
Ann Nucl Med 1998 Aug;12(4):221-3. doi: 10.1007/BF03164850. PMID: 9795710
Fibrosarcoma versus fibromatoses and cellular nodular fasciitis. A comparative study of their proliferative activity using proliferating cell nuclear antigen, DNA flow cytometry, and p53.
Oshiro Y, Fukuda T, Tsuneyoshi M
Am J Surg Pathol 1994 Jul;18(7):712-9. PMID: 7517104

Clinical prediction guides

Surgical outcomes following resection for sporadic abdominal wall fibromatosis.
Wilkinson MJ, Chan KE, Hayes AJ, Strauss DC
Ann Surg Oncol 2014 Jul;21(7):2144-9. Epub 2014 Mar 7 doi: 10.1245/s10434-014-3618-5. PMID: 24604586
Aggressive fibromatosis from infancy to adolescence.
Spiegel DA, Dormans JP, Meyer JS, Himelstein B, Mathur S, Asada N, Womer RB
J Pediatr Orthop 1999 Nov-Dec;19(6):776-84. PMID: 10573349
Fibrosarcoma versus fibromatoses and cellular nodular fasciitis. A comparative study of their proliferative activity using proliferating cell nuclear antigen, DNA flow cytometry, and p53.
Oshiro Y, Fukuda T, Tsuneyoshi M
Am J Surg Pathol 1994 Jul;18(7):712-9. PMID: 7517104

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