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Carcinoma of supraglottis

MedGen UID:
266243
•Concept ID:
C1299240
•
Neoplastic Process
Synonyms: Cancer of Supraglottis; cancer of supraglottis; Cancer of the Supraglottis; cancer of the supraglottis; carcinoma of supraglottic part of larynx; Carcinoma of Supraglottis; carcinoma of supraglottis; Carcinoma of the Supraglottis; carcinoma of the supraglottis; Supraglottic Cancer; supraglottic cancer; Supraglottic Carcinoma; supraglottic carcinoma; supraglottic part of larynx carcinoma; supraglottic throat cancer; Supraglottis Carcinoma; supraglottis carcinoma
SNOMED CT: Carcinoma of supraglottis (372105009)
 
Monarch Initiative: MONDO:0004357

Definition

A carcinoma of the larynx that arises from the supraglottic area. [from NCI]

Professional guidelines

PubMed

Treatment of early-stage laryngeal cancer: A comparison of treatment options.
Baird BJ, Sung CK, Beadle BM, Divi V
Oral Oncol 2018 Dec;87:8-16. Epub 2018 Oct 16 doi: 10.1016/j.oraloncology.2018.09.012. PMID: 30527248
Management of cancer of the supraglottis.
Scola B, Fernández-Vega M, Martínez T, Fernández-Vega S, Ramirez C
Otolaryngol Head Neck Surg 2001 Feb;124(2):195-8. doi: 10.1067/mhn.2001.112202. PMID: 11226956
Controversies in the diagnosis and treatment of early carcinoma of the larynx.
Loré JM Jr
Semin Surg Oncol 1991 Jan-Feb;7(1):31-7. doi: 10.1002/ssu.2980070108. PMID: 2003183

Recent clinical studies

Etiology

Mu-Opioid Receptor Expression in Laryngeal Cancer.
Lahav Y, Cohen O, Huszar M, Levy I, Cata JP, Halperin D, Shoffel-Havakuk H
J Voice 2023 May;37(3):433-439. Epub 2021 Mar 7 doi: 10.1016/j.jvoice.2021.02.018. PMID: 33750623
Advances in Organ Preservation for Laryngeal Cancer.
Campbell G, Glazer TA, Kimple RJ, Bruce JY
Curr Treat Options Oncol 2022 Apr;23(4):594-608. Epub 2022 Mar 18 doi: 10.1007/s11864-022-00945-5. PMID: 35303749Free PMC Article
Supraglottic Squamous Cell Carcinoma: A Population-Based Study of 22,675 Cases.
Patel TD, Echanique KA, Yip C, Hsueh WD, Baredes S, Park RCW, Eloy JA
Laryngoscope 2019 Aug;129(8):1822-1827. Epub 2018 Dec 11 doi: 10.1002/lary.27592. PMID: 30536822
Management of cancer of the supraglottis.
Scola B, Fernández-Vega M, Martínez T, Fernández-Vega S, Ramirez C
Otolaryngol Head Neck Surg 2001 Feb;124(2):195-8. doi: 10.1067/mhn.2001.112202. PMID: 11226956
Results of conservation surgery for cancers of the supraglottis and pyriform sinus.
Ogura JH, Marks JE, Freeman RB
Laryngoscope 1980 Apr;90(4):591-600. doi: 10.1288/00005537-198004000-00005. PMID: 7359978

Diagnosis

Bone marrow metastasis/carcinomatosis in head and neck squamous cell carcinoma.
Lk Wong B, Wei Chern Gan R, Adabavazeh B, Jose J
J Oral Pathol Med 2021 Nov;50(10):955-961. Epub 2021 Apr 13 doi: 10.1111/jop.13184. PMID: 33818835
Supraglottic Squamous Cell Carcinoma: A Population-Based Study of 22,675 Cases.
Patel TD, Echanique KA, Yip C, Hsueh WD, Baredes S, Park RCW, Eloy JA
Laryngoscope 2019 Aug;129(8):1822-1827. Epub 2018 Dec 11 doi: 10.1002/lary.27592. PMID: 30536822
Warthin tumor of the larynx: A case report and review of the literature.
Duek I, Paker M, Gil Z, Cohen JT
Ear Nose Throat J 2018 Jul;97(7):E8-E11. PMID: 30036439
NUT midline carcinoma of the larynx: an international series and review of the literature.
Hellquist H, French CA, Bishop JA, Coca-Pelaz A, Propst EJ, Paiva Correia A, Ngan BY, Grant R, Cipriani NA, Vokes D, Henrique R, Pardal F, Vizcaino JR, Rinaldo A, Ferlito A
Histopathology 2017 May;70(6):861-868. Epub 2017 Feb 21 doi: 10.1111/his.13143. PMID: 27926786Free PMC Article
Controversies in the diagnosis and treatment of early carcinoma of the larynx.
Loré JM Jr
Semin Surg Oncol 1991 Jan-Feb;7(1):31-7. doi: 10.1002/ssu.2980070108. PMID: 2003183

Therapy

Advances in Organ Preservation for Laryngeal Cancer.
Campbell G, Glazer TA, Kimple RJ, Bruce JY
Curr Treat Options Oncol 2022 Apr;23(4):594-608. Epub 2022 Mar 18 doi: 10.1007/s11864-022-00945-5. PMID: 35303749Free PMC Article
Treatment of early-stage laryngeal cancer: A comparison of treatment options.
Baird BJ, Sung CK, Beadle BM, Divi V
Oral Oncol 2018 Dec;87:8-16. Epub 2018 Oct 16 doi: 10.1016/j.oraloncology.2018.09.012. PMID: 30527248
Basaloid squamous cell carcinoma of the larynx--A systematic review.
Thankappan K
Auris Nasus Larynx 2012 Aug;39(4):397-401. Epub 2011 Aug 24 doi: 10.1016/j.anl.2011.07.018. PMID: 21868181
Complications of supraglottic laryngectomy for carcinomas of the supraglottis and the base of the tongue.
Suarez C, Rodrigo JP, Herranz J, Diaz C, Fernandez JA
Clin Otolaryngol Allied Sci 1996 Feb;21(1):87-90. doi: 10.1111/j.1365-2273.1996.tb01032.x. PMID: 8674231
Results of conservation surgery for cancers of the supraglottis and pyriform sinus.
Ogura JH, Marks JE, Freeman RB
Laryngoscope 1980 Apr;90(4):591-600. doi: 10.1288/00005537-198004000-00005. PMID: 7359978

Prognosis

Bone marrow metastasis/carcinomatosis in head and neck squamous cell carcinoma.
Lk Wong B, Wei Chern Gan R, Adabavazeh B, Jose J
J Oral Pathol Med 2021 Nov;50(10):955-961. Epub 2021 Apr 13 doi: 10.1111/jop.13184. PMID: 33818835
Supraglottic Squamous Cell Carcinoma: A Population-Based Study of 22,675 Cases.
Patel TD, Echanique KA, Yip C, Hsueh WD, Baredes S, Park RCW, Eloy JA
Laryngoscope 2019 Aug;129(8):1822-1827. Epub 2018 Dec 11 doi: 10.1002/lary.27592. PMID: 30536822
Treatment of early-stage laryngeal cancer: A comparison of treatment options.
Baird BJ, Sung CK, Beadle BM, Divi V
Oral Oncol 2018 Dec;87:8-16. Epub 2018 Oct 16 doi: 10.1016/j.oraloncology.2018.09.012. PMID: 30527248
Controversies in the diagnosis and treatment of early carcinoma of the larynx.
Loré JM Jr
Semin Surg Oncol 1991 Jan-Feb;7(1):31-7. doi: 10.1002/ssu.2980070108. PMID: 2003183
Results of conservation surgery for cancers of the supraglottis and pyriform sinus.
Ogura JH, Marks JE, Freeman RB
Laryngoscope 1980 Apr;90(4):591-600. doi: 10.1288/00005537-198004000-00005. PMID: 7359978

Clinical prediction guides

Can Red Blood Cell Distribution Width Predict Laryngectomy Complications or Survival Outcomes?
Marcus K, Sullivan CB, Al-Qurayshi Z, Buchakjian MR
Ann Otol Rhinol Laryngol 2022 Oct;131(10):1102-1108. Epub 2021 Oct 29 doi: 10.1177/00034894211056117. PMID: 34715735
Neuroendocrine Neoplasms of the Larynx: A Clinicopathologic Analysis of 27 Neuroendocrine Tumors and Neuroendocrine Carcinomas.
Bal M, Sharma A, Rane SU, Mittal N, Chaukar D, Prabhash K, Patil A
Head Neck Pathol 2022 Jun;16(2):375-387. Epub 2021 Aug 16 doi: 10.1007/s12105-021-01367-9. PMID: 34401980Free PMC Article
Prevalence of Synchronous ESCN in Head and Neck Cancer: A Single-Institution Perspective.
Thakur K, Singh CA, Thakar A, Kakkar A, Sikka K, Kumar R, Sharma SC
Laryngoscope 2021 Mar;131(3):E807-E814. Epub 2020 Jul 3 doi: 10.1002/lary.28821. PMID: 32619324
Role of narrow-band imaging in detection of head and neck unknown primary squamous cell carcinoma.
Filauro M, Paderno A, Perotti P, Marchi F, Garofolo S, Peretti G, Piazza C
Laryngoscope 2018 Sep;128(9):2060-2066. Epub 2018 Feb 2 doi: 10.1002/lary.27098. PMID: 29392723
Contribution of tobacco and alcohol to the high rates of squamous cell carcinoma of the supraglottis and glottis in Central Europe.
Hashibe M, Boffetta P, Zaridze D, Shangina O, Szeszenia-Dabrowska N, Mates D, Fabiánová E, Rudnai P, Brennan P
Am J Epidemiol 2007 Apr 1;165(7):814-20. Epub 2007 Jan 22 doi: 10.1093/aje/kwk066. PMID: 17244634

Recent systematic reviews

Epidemiological, clinical and oncological outcomes of young patients with laryngeal cancer: a systematic review.
Lechien JR, Maniaci A, Hans S, Iannella G, Fakhry N, Mayo-Yáñez M, Ayad T, Mannelli G, Chiesa-Estomba CM
Eur Arch Otorhinolaryngol 2022 Dec;279(12):5741-5753. Epub 2022 Jun 2 doi: 10.1007/s00405-022-07466-9. PMID: 35652941
Diagnostic value of sentinel lymph node biopsy in head and neck cancer: a meta-analysis.
Thompson CF, St John MA, Lawson G, Grogan T, Elashoff D, Mendelsohn AH
Eur Arch Otorhinolaryngol 2013 Jul;270(7):2115-22. Epub 2012 Dec 22 doi: 10.1007/s00405-012-2320-0. PMID: 23263205Free PMC Article
Basaloid squamous cell carcinoma of the larynx--A systematic review.
Thankappan K
Auris Nasus Larynx 2012 Aug;39(4):397-401. Epub 2011 Aug 24 doi: 10.1016/j.anl.2011.07.018. PMID: 21868181

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