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Adenosquamous breast carcinoma

MedGen UID:
267645
•Concept ID:
C1510796
•
Neoplastic Process
Synonyms: Adenosquamous Breast Carcinoma; adenosquamous breast carcinoma; Breast Adenosquamous Carcinoma; breast adenosquamous carcinoma; metaplastic adenosquamous carcinoma
 
Monarch Initiative: MONDO:0003548

Definition

An invasive breast carcinoma characterized by the presence of tubular and glandular neoplastic cell structures, admixed with islands of neoplastic cells showing squamous differentiation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdenosquamous breast carcinoma

Professional guidelines

PubMed

Cost-effectiveness analysis of pembrolizumab for treatment of US patients with persistent, recurrent, or metastatic cervical cancer.
Shi Y, Chen J, Shi B, Liu A
Gynecol Oncol 2022 Feb;164(2):379-385. Epub 2021 Dec 16 doi: 10.1016/j.ygyno.2021.12.007. PMID: 34920886
Breast lesions of uncertain malignant nature and limited metastatic potential: proposals to improve their recognition and clinical management.
Rakha EA, Badve S, Eusebi V, Reis-Filho JS, Fox SB, Dabbs DJ, Decker T, Hodi Z, Ichihara S, Lee AH, Palacios J, Richardson AL, Vincent-Salomon A, Schmitt FC, Tan PH, Tse GM, Ellis IO
Histopathology 2016 Jan;68(1):45-56. doi: 10.1111/his.12861. PMID: 26348644Free PMC Article

Recent clinical studies

Etiology

Lactating breast abscess: a rare presentation of adenosquamous breast carcinoma.
Alipour S, Seifollahi A, Anbiaee R
Singapore Med J 2013 Dec;54(12):e247-9. doi: 10.11622/smedj.2013251. PMID: 24356765

Diagnosis

Adenosquamous carcinoma of the breast, an uncommon diagnosis with poor prognosis-Lessons learned from a 12-year analysis of the National Cancer Database.
Cochrane K, Bell JL, Heidel RE, Orucevic A
Breast J 2021 Feb;27(2):165-169. Epub 2021 Jan 22 doi: 10.1111/tbj.14135. PMID: 33482684
Keloidal-like local recurrence after infiltrating adenosquamous breast carcinoma with stromal-overgrowth mimicking a benign skin lesion.
Stolnicu S, Giurgi A, Naznean A, Podoleanu C, Chiriac A
Pol J Pathol 2018;69(1):93-97. doi: 10.5114/pjp.2018.75343. PMID: 29895133
Lactating breast abscess: a rare presentation of adenosquamous breast carcinoma.
Alipour S, Seifollahi A, Anbiaee R
Singapore Med J 2013 Dec;54(12):e247-9. doi: 10.11622/smedj.2013251. PMID: 24356765

Prognosis

Adenosquamous carcinoma of the breast, an uncommon diagnosis with poor prognosis-Lessons learned from a 12-year analysis of the National Cancer Database.
Cochrane K, Bell JL, Heidel RE, Orucevic A
Breast J 2021 Feb;27(2):165-169. Epub 2021 Jan 22 doi: 10.1111/tbj.14135. PMID: 33482684
Keloidal-like local recurrence after infiltrating adenosquamous breast carcinoma with stromal-overgrowth mimicking a benign skin lesion.
Stolnicu S, Giurgi A, Naznean A, Podoleanu C, Chiriac A
Pol J Pathol 2018;69(1):93-97. doi: 10.5114/pjp.2018.75343. PMID: 29895133

Clinical prediction guides

Keloidal-like local recurrence after infiltrating adenosquamous breast carcinoma with stromal-overgrowth mimicking a benign skin lesion.
Stolnicu S, Giurgi A, Naznean A, Podoleanu C, Chiriac A
Pol J Pathol 2018;69(1):93-97. doi: 10.5114/pjp.2018.75343. PMID: 29895133

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