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Breast Soft Tissue Neoplasm

MedGen UID:: 267907
•Concept ID:: C1511323
•: Neoplastic Process

Synonym:

Breast Soft Tissue Tumor

Definition

A benign, intermediate, or malignant mesenchymal neoplasm that arises from the breast. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBreast Soft Tissue Neoplasm

Phenotypic abnormality
- Abnormality of the breast
  - Abnormal breast morphology
    - Breast neoplasm
      - Breast Soft Tissue Neoplasm
        Breast granular cell tumor
        Breast Inflammatory Myofibroblastic Tumor
        Breast leiomyoma
        Breast lipoma
        Breast Angiolipoma
        Breast myoepithelial tumor
        Breast adenomyoepithelioma
        Benign breast adenomyoepithelioma
        Malignant Breast Adenomyoepithelioma
        Breast myoepitheliosis
        Breast Atypical Myoepitheliosis
        Intraductal breast myoepitheliosis
        Periductal breast myoepitheliosis
        Malignant breast myoepithelioma
        Breast myofibroblastoma
        Breast Nodular Fasciitis
        Breast Periductal Stromal Tumor
        Breast sarcoma
        Breast angiosarcoma
        Postradiation Breast Angiosarcoma
        Primary Breast Angiosarcoma
        Recurrent Breast Angiosarcoma
        Breast extraskeletal osteosarcoma
        Breast fibrosarcoma
        Breast leiomyosarcoma
        Breast liposarcoma
        Breast rhabdomyosarcoma
        Recurrent Breast Sarcoma
        Breast Vascular Neoplasm
        Breast angiomatosis
        Breast hemangioma
        Breast capillary hemangioma
        Breast epithelioid hemangioma

Professional guidelines

PubMed

Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China.

Xu C, Si L, Wang W, Li Z, Song Z, Wang Q, Liu A, Yu J, Fang W, Zhong W, Wang Z, Zhang Y, Liu J, Zhang S, Cai X, Liu A, Li W, Zhan P, Liu H, Lv T, Miao L, Min L, Chen Y, Yuan J, Wang F, Jiang Z, Lin G, Pu X, Lin R, Liu W, Rao C, Lv D, Yu Z, Lei L, Li X, Tang C, Zhou C, Zhang J, Xue J, Guo H, Chu Q, Meng R, Wu J, Zhang R, Hu X, Zhou J, Zhu Z, Li Y, Qiu H, Xia F, Lu Y, Chen X, Ge R, Dai E, Han Y, Pan W, Luo J, Jia H, Dong X, Pang F, Wang K, Wang L, Zhu Y, Xie Y, Lin X, Cai J, Wei J, Lan F, Feng H, Wang L, Du Y, Yao W, Shi X, Niu X, Yuan D, Yao Y, Huang J, Zhang Y, Sun P, Wang H, Ye M, Wang D, Wang Z, Wan B, Lv D, Wei Q, Kang J, Zhang J, Zhang C, Yu G, Ou J, Shi L, Li Z, Liu Z, Liu J, Yang N, Wu L, Wang H, Jin G, Yang L, Wang G, Fang M, Fang Y, Li Y, Wang X, Zhang Y, Ma S, Wang B, Zhang X, Song Y, Lu Y
Thorac Cancer 2022 Nov;13(21):3084-3097. Epub 2022 Sep 20 doi: 10.1111/1759-7714.14644. PMID: 36127731 Free PMC Article

Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.

Daly MB, Pal T, Berry MP, Buys SS, Dickson P, Domchek SM, Elkhanany A, Friedman S, Goggins M, Hutton ML; CGC, Karlan BY, Khan S, Klein C, Kohlmann W; CGC, Kurian AW, Laronga C, Litton JK, Mak JS; LCGC, Menendez CS, Merajver SD, Norquist BS, Offit K, Pederson HJ, Reiser G; CGC, Senter-Jamieson L; CGC, Shannon KM, Shatsky R, Visvanathan K, Weitzel JN, Wick MJ, Wisinski KB, Yurgelun MB, Darlow SD, Dwyer MA
J Natl Compr Canc Netw 2021 Jan 6;19(1):77-102. doi: 10.6004/jnccn.2021.0001. PMID: 33406487

Surgical Treatment of Lymphedema.

Schaverien MV, Coroneos CJ
Plast Reconstr Surg 2019 Sep;144(3):738-758. doi: 10.1097/PRS.0000000000005993. PMID: 31461041

See all (179)

Recent clinical studies

Etiology

Radiation-induced angiosarcoma of the breast: A review.

Bonito FJP, de Almeida Cerejeira D, Dahlstedt-Ferreira C, Oliveira Coelho H, Rosas R
Breast J 2020 Mar;26(3):458-463. Epub 2019 Aug 25 doi: 10.1111/tbj.13504. PMID: 31448482

Current Technique and Application of Percutaneous Cryotherapy.

Mahnken AH, König AM, Figiel JH
Rofo 2018 Sep;190(9):836-846. Epub 2018 Apr 17 doi: 10.1055/a-0598-5134. PMID: 29665588

Nipple-Sparing Mastectomy and Direct-to-Implant Breast Reconstruction.

Colwell AS, Christensen JM
Plast Reconstr Surg 2017 Nov;140(5S Advances in Breast Reconstruction):44S-50S. doi: 10.1097/PRS.0000000000003949. PMID: 29064921

Sarcoma of the breast: an update on a rare entity.

Lim SZ, Ong KW, Tan BK, Selvarajan S, Tan PH
J Clin Pathol 2016 May;69(5):373-81. Epub 2016 Jan 4 doi: 10.1136/jclinpath-2015-203545. PMID: 26729013

Stem cells from adipose tissue and breast cancer: hype, risks and hope.

Bertolini F, Petit JY, Kolonin MG
Br J Cancer 2015 Feb 3;112(3):419-23. Epub 2015 Jan 13 doi: 10.1038/bjc.2014.657. PMID: 25584493 Free PMC Article

See all (1137)

Diagnosis

Veiga LHS, Vo JB, Curtis RE, Mille MM, Lee C, Ramin C, Bodelon C, Aiello Bowles EJ, Buist DSM, Weinmann S, Feigelson HS, Gierach GL, Berrington de Gonzalez A
Lancet Oncol 2022 Nov;23(11):1451-1464. Epub 2022 Oct 11 doi: 10.1016/S1470-2045(22)00561-7. PMID: 36240805 Free PMC Article

The potential of predictive and prognostic breast MRI (P2-bMRI).

Dietzel M, Trimboli RM, Zanardo M, Schultz-Wendtland R, Uder M, Clauser P, Sardanelli F, Baltzer PAT
Eur Radiol Exp 2022 Aug 22;6(1):42. doi: 10.1186/s41747-022-00291-z. PMID: 35989400 Free PMC Article

Primary Osteosarcoma of the Breast: Pathophysiology and Imaging Review.

Mujtaba B, Nassar SM, Aslam R, Garg N, Madewell JE, Taher A, Hanafy AK, Whitman G
Curr Probl Diagn Radiol 2020 Mar-Apr;49(2):116-123. Epub 2019 Jan 3 doi: 10.1067/j.cpradiol.2019.01.001. PMID: 30655112

Sarcoma of the breast: an update on a rare entity.

Lim SZ, Ong KW, Tan BK, Selvarajan S, Tan PH
J Clin Pathol 2016 May;69(5):373-81. Epub 2016 Jan 4 doi: 10.1136/jclinpath-2015-203545. PMID: 26729013

From morphological to molecular diagnosis of soft tissue tumors.

Miettinen M
Adv Exp Med Biol 2006;587:99-113. doi: 10.1007/978-1-4020-5133-3_10. PMID: 17163160

See all (1353)

Therapy

Current Technique and Application of Percutaneous Cryotherapy.

Mahnken AH, König AM, Figiel JH
Rofo 2018 Sep;190(9):836-846. Epub 2018 Apr 17 doi: 10.1055/a-0598-5134. PMID: 29665588

Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy.

Choi W, Porten S, Kim S, Willis D, Plimack ER, Hoffman-Censits J, Roth B, Cheng T, Tran M, Lee IL, Melquist J, Bondaruk J, Majewski T, Zhang S, Pretzsch S, Baggerly K, Siefker-Radtke A, Czerniak B, Dinney CP, McConkey DJ
Cancer Cell 2014 Feb 10;25(2):152-65. doi: 10.1016/j.ccr.2014.01.009. PMID: 24525232 Free PMC Article

Ridaforolimus.

Drugs R D 2010;10(3):165-78. doi: 10.2165/11586010-000000000-00000. PMID: 20945947 Free PMC Article

Docetaxel.

Cortes JE, Pazdur R
J Clin Oncol 1995 Oct;13(10):2643-55. doi: 10.1200/JCO.1995.13.10.2643. PMID: 7595719

Infusion-embolization.

Wallace S, Charnsangavej C, Carrasco CH, Bechtel W
Cancer 1984 Dec 1;54(11 Suppl):2751-65. doi: 10.1002/1097-0142(19841201)54:2+<2751::aid-cncr2820541423>3.0.co;2-5. PMID: 6093984

See all (989)

Prognosis

Soft tissue sarcoma incidences and clinical characteristics are significantly different in France and Taiwan.

Chen TW, Chiang RC, Le Cesne A, Hsieh YC, Italiano A, Yang YW, Penel N, Lee WC, Bompas E, Valentin T, Anract P, Firmin N, Duffaud F, Cheng AL, Ducimetiere F, Chan KA, Blay JY
Cancer 2022 Sep 15;128(18):3360-3369. Epub 2022 Jul 7 doi: 10.1002/cncr.34372. PMID: 35796499

Pan-cancer analysis of prognostic metastatic phenotypes.

Zaorsky NG, Wang X, Garrett SM, Lehrer EJ, Lin C, DeGraff DJ, Spratt DE, Trifiletti DM, Kishan AU, Showalter TN, Park HS, Yang JT, Chinchilli VM, Wang M
Int J Cancer 2022 Jan 1;150(1):132-141. Epub 2021 Aug 27 doi: 10.1002/ijc.33744. PMID: 34287840 Free PMC Article

Did we solve soft tissue (breast) attenuation?

Henzlova MJ, Duvall WL
J Nucl Cardiol 2021 Jun;28(3):898-900. Epub 2019 Aug 28 doi: 10.1007/s12350-019-01870-1. PMID: 31463817

Current Technique and Application of Percutaneous Cryotherapy.

Mahnken AH, König AM, Figiel JH
Rofo 2018 Sep;190(9):836-846. Epub 2018 Apr 17 doi: 10.1055/a-0598-5134. PMID: 29665588

Sarcoma of the breast: an update on a rare entity.

Lim SZ, Ong KW, Tan BK, Selvarajan S, Tan PH
J Clin Pathol 2016 May;69(5):373-81. Epub 2016 Jan 4 doi: 10.1136/jclinpath-2015-203545. PMID: 26729013

See all (1041)

Clinical prediction guides

A Role of PET/MR in Breast Cancer?

Bruckmann NM, Morawitz J, Fendler WP, Ruckhäberle E, Bittner AK, Giesel FL, Herrmann K, Antoch G, Umutlu L, Kirchner J
Semin Nucl Med 2022 Sep;52(5):611-618. Epub 2022 Mar 5 doi: 10.1053/j.semnuclmed.2022.01.003. PMID: 35260243

Pan-cancer analysis of prognostic metastatic phenotypes.

Nomogram for predicting overall survival in colorectal cancer with distant metastasis.

Liu Z, Xu Y, Xu G, Baklaushev VP, Chekhonin VP, Peltzer K, Ma W, Wang X, Wang G, Zhang C
BMC Gastroenterol 2021 Mar 4;21(1):103. doi: 10.1186/s12876-021-01692-x. PMID: 33663400 Free PMC Article

Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy.

Angiosarcoma.

Young RJ, Brown NJ, Reed MW, Hughes D, Woll PJ
Lancet Oncol 2010 Oct;11(10):983-91. Epub 2010 May 25 doi: 10.1016/S1470-2045(10)70023-1. PMID: 20537949

See all (843)

Recent systematic reviews

Extramedullary disease in multiple myeloma: a systematic literature review.

Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675 Free PMC Article

Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies.

Cupp MA, Cariolou M, Tzoulaki I, Aune D, Evangelou E, Berlanga-Taylor AJ
BMC Med 2020 Nov 20;18(1):360. doi: 10.1186/s12916-020-01817-1. PMID: 33213430 Free PMC Article

Systemic antibiotics for treating malignant wounds.

Ramasubbu DA, Smith V, Hayden F, Cronin P
Cochrane Database Syst Rev 2017 Aug 24;8(8):CD011609. doi: 10.1002/14651858.CD011609.pub2. PMID: 28837757 Free PMC Article

High frequency of lobular breast cancer in distant metastases to the orbit.

Raap M, Antonopoulos W, Dämmrich M, Christgen H, Steinmann D, Länger F, Lehmann U, Kreipe H, Christgen M
Cancer Med 2015 Jan;4(1):104-11. Epub 2014 Oct 30 doi: 10.1002/cam4.331. PMID: 25355547 Free PMC Article

A systematic overview of radiation therapy effects in soft tissue sarcomas.

Strander H, Turesson I, Cavallin-Ståhl E
Acta Oncol 2003;42(5-6):516-31. doi: 10.1080/02841860310014732. PMID: 14596510

See all (25)

MedGen

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Breast Soft Tissue Neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Recent activity