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Bluetongue

MedGen UID:
2687
•Concept ID:
C0005866
•
Disease or Syndrome
Synonyms: Blue Tongue; Tongue, Blue

Definition

A reovirus infection, chiefly of sheep, characterized by a swollen blue tongue, catarrhal inflammation of upper respiratory and gastrointestinal tracts, and often by inflammation of sensitive laminae of the feet and coronet. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBluetongue

Professional guidelines

PubMed

Bluetongue disease risk assessment based on observed and projected Culicoides obsoletus spp. vector densities.
Brugger K, Rubel F
PLoS One 2013;8(4):e60330. Epub 2013 Apr 1 doi: 10.1371/journal.pone.0060330. PMID: 23560090Free PMC Article

Recent clinical studies

Etiology

Trans-Acting RNA-RNA Interactions in Segmented RNA Viruses.
Newburn LR, White KA
Viruses 2019 Aug 14;11(8) doi: 10.3390/v11080751. PMID: 31416187Free PMC Article
RECENT CHANGES IN INFECTIOUS DISEASES IN EUROPEAN WILDLIFE.
Yon L, Duff JP, Ågren EO, Erdélyi K, Ferroglio E, Godfroid J, Hars J, Hestvik G, Horton D, Kuiken T, Lavazza A, Markowska-Daniel I, Martel A, Neimanis A, Pasmans F, Price SJ, Ruiz-Fons F, Ryser-Degiorgis MP, Widén F, Gavier-Widén D
J Wildl Dis 2019 Jan;55(1):3-43. Epub 2018 Oct 4 doi: 10.7589/2017-07-172. PMID: 30284963
Zoonotic risks from small ruminants.
Ganter M
Vet Microbiol 2015 Dec 14;181(1-2):53-65. Epub 2015 Jul 15 doi: 10.1016/j.vetmic.2015.07.015. PMID: 26275853
Arbovirus vaccines; opportunities for the baculovirus-insect cell expression system.
Metz SW, Pijlman GP
J Invertebr Pathol 2011 Jul;107 Suppl:S16-30. doi: 10.1016/j.jip.2011.05.002. PMID: 21784227
Present and future arboviral threats.
Weaver SC, Reisen WK
Antiviral Res 2010 Feb;85(2):328-45. Epub 2009 Oct 24 doi: 10.1016/j.antiviral.2009.10.008. PMID: 19857523Free PMC Article

Diagnosis

Identifying climate-sensitive infectious diseases in animals and humans in Northern regions.
Omazic A, Bylund H, Boqvist S, Högberg A, Björkman C, Tryland M, Evengård B, Koch A, Berggren C, Malogolovkin A, Kolbasov D, Pavelko N, Thierfelder T, Albihn A
Acta Vet Scand 2019 Nov 14;61(1):53. doi: 10.1186/s13028-019-0490-0. PMID: 31727129Free PMC Article
Zoonotic and emerging orbivirus infections.
Attoui H, Mohd Jaafar F
Rev Sci Tech 2015 Aug;34(2):353-61. doi: 10.20506/rst.34.2.2362. PMID: 26601440
Zoonotic risks from small ruminants.
Ganter M
Vet Microbiol 2015 Dec 14;181(1-2):53-65. Epub 2015 Jul 15 doi: 10.1016/j.vetmic.2015.07.015. PMID: 26275853
Orbiviruses: A North American Perspective.
McVey DS, Drolet BS, Ruder MG, Wilson WC, Nayduch D, Pfannenstiel R, Cohnstaedt LW, MacLachlan NJ, Gay CG
Vector Borne Zoonotic Dis 2015 Jun;15(6):335-8. doi: 10.1089/vbz.2014.1699. PMID: 26086554
Genetically engineered particulate virus-like structures and their use as vaccine delivery systems.
Roy P
Intervirology 1996;39(1-2):62-71. doi: 10.1159/000150476. PMID: 8957671

Therapy

Inhibition of Orbivirus Replication by Fluvastatin and Identification of the Key Elements of the Mevalonate Pathway Involved.
Mohd Jaafar F, Monsion B, Belhouchet M, Mertens PPC, Attoui H
Viruses 2021 Jul 23;13(8) doi: 10.3390/v13081437. PMID: 34452303Free PMC Article
Genetic and phylogenetic characterization of polycistronic dsRNA segment-10 of bluetongue virus isolates from India between 1985 and 2011.
Biswas SK, Mondal B, Chand K, Nautiyal S, Subramaniam S, Singh KP, Gupta VK, Ramakrishnan MA
Virus Genes 2021 Aug;57(4):369-379. Epub 2021 Jun 12 doi: 10.1007/s11262-021-01855-8. PMID: 34120252
Bluetongue Virus Particles as Nanoreactors for Enzyme Delivery and Cancer Therapy.
Thuenemann EC, Le DHT, Lomonossoff GP, Steinmetz NF
Mol Pharm 2021 Mar 1;18(3):1150-1156. Epub 2021 Feb 10 doi: 10.1021/acs.molpharmaceut.0c01053. PMID: 33566625Free PMC Article
Meeting report VLPNPV: Session 5: Plant based technology.
Meador LR, Mor TS
Hum Vaccin Immunother 2014;10(10):3068-73. doi: 10.4161/21645515.2014.979693. PMID: 25581535Free PMC Article
Developing country applications of molecular farming: case studies in South Africa and Argentina.
Rybicki EP, Hitzeroth II, Meyers A, Dus Santos MJ, Wigdorovitz A
Curr Pharm Des 2013;19(31):5612-21. doi: 10.2174/1381612811319310015. PMID: 23394557

Prognosis

Towards a resource-based habitat approach for spatial modelling of vector-borne disease risks.
Hartemink N, Vanwambeke SO, Purse BV, Gilbert M, Van Dyck H
Biol Rev Camb Philos Soc 2015 Nov;90(4):1151-62. Epub 2014 Oct 22 doi: 10.1111/brv.12149. PMID: 25335785
The arrival, establishment and spread of exotic diseases: patterns and predictions.
Randolph SE, Rogers DJ
Nat Rev Microbiol 2010 May;8(5):361-71. Epub 2010 Apr 7 doi: 10.1038/nrmicro2336. PMID: 20372156
Challenges in predicting climate and environmental effects on vector-borne disease episystems in a changing world.
Tabachnick WJ
J Exp Biol 2010 Mar 15;213(6):946-54. doi: 10.1242/jeb.037564. PMID: 20190119
Potential arbovirus emergence and implications for the United Kingdom.
Gould EA, Higgs S, Buckley A, Gritsun TS
Emerg Infect Dis 2006 Apr;12(4):549-55. doi: 10.3201/eid1204.051010. PMID: 16704800Free PMC Article
Climate change: effects on culicoides--transmitted viruses and implications for the UK.
Wittmann EJ, Baylis M
Vet J 2000 Sep;160(2):107-17. doi: 10.1053/tvjl.2000.0470. PMID: 10985802

Clinical prediction guides

Towards a resource-based habitat approach for spatial modelling of vector-borne disease risks.
Hartemink N, Vanwambeke SO, Purse BV, Gilbert M, Van Dyck H
Biol Rev Camb Philos Soc 2015 Nov;90(4):1151-62. Epub 2014 Oct 22 doi: 10.1111/brv.12149. PMID: 25335785
The arrival, establishment and spread of exotic diseases: patterns and predictions.
Randolph SE, Rogers DJ
Nat Rev Microbiol 2010 May;8(5):361-71. Epub 2010 Apr 7 doi: 10.1038/nrmicro2336. PMID: 20372156
Challenges in predicting climate and environmental effects on vector-borne disease episystems in a changing world.
Tabachnick WJ
J Exp Biol 2010 Mar 15;213(6):946-54. doi: 10.1242/jeb.037564. PMID: 20190119
Potential arbovirus emergence and implications for the United Kingdom.
Gould EA, Higgs S, Buckley A, Gritsun TS
Emerg Infect Dis 2006 Apr;12(4):549-55. doi: 10.3201/eid1204.051010. PMID: 16704800Free PMC Article
Climate change: effects on culicoides--transmitted viruses and implications for the UK.
Wittmann EJ, Baylis M
Vet J 2000 Sep;160(2):107-17. doi: 10.1053/tvjl.2000.0470. PMID: 10985802

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