U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Prostate Ductal Adenocarcinoma, Solid Pattern

MedGen UID:
271581
•Concept ID:
C1514513
•
Neoplastic Process

Definition

A prostate ductal adenocarcinoma characterized by the presence of cribriform and/or papillary patterns and areas of solid nests of malignant cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProstate Ductal Adenocarcinoma, Solid Pattern

Recent clinical studies

Etiology

Evaluation of tumor morphologies and association with biochemical recurrence after radical prostatectomy in grade group 5 prostate cancer.
Flood TA, Schieda N, Sim J, Breau RH, Morash C, Belanger EC, Robertson SJ
Virchows Arch 2018 Feb;472(2):205-212. Epub 2017 Oct 3 doi: 10.1007/s00428-017-2241-9. PMID: 28975495
Intraductal carcinoma of the prostate on needle biopsy: Histologic features and clinical significance.
Guo CC, Epstein JI
Mod Pathol 2006 Dec;19(12):1528-35. Epub 2006 Sep 15 doi: 10.1038/modpathol.3800702. PMID: 16980940
Metastatic ductal adenocarcinoma of the prostate: cytologic features and clinical findings.
Gong Y, Caraway N, Stewart J, Staerkel G
Am J Clin Pathol 2006 Aug;126(2):302-9. doi: 10.1309/4TT6-LVJP-QVFW-DB6P. PMID: 16891207
Rare prostatic carcinomas: histogenesis and morphologic pattern.
Losi L, Brausi M, Di Gregorio C
Pathologica 1994 Aug;86(4):366-70. PMID: 7708435

Diagnosis

The presence and clinical implication of intraductal carcinoma of prostate in metastatic castration resistant prostate cancer.
Chen Z, Chen N, Shen P, Gong J, Li X, Zhao T, Liao B, Liu L, Liu Z, Zhang X, Liu J, Peng Z, Chen X, Xu M, Gui H, Zhang P, Wei Q, Zhou Q, Zeng H
Prostate 2015 Sep;75(12):1247-54. Epub 2015 Apr 27 doi: 10.1002/pros.23005. PMID: 25917338
Ductal adenocarcinoma of the prostate: current opinion and controversies.
Samaratunga H, Delahunt B
Anal Quant Cytol Histol 2008 Aug;30(4):237-46. PMID: 18773743
High-grade prostatic intraepithelial neoplasialike ductal adenocarcinoma of the prostate: a clinicopathologic study of 28 cases.
Tavora F, Epstein JI
Am J Surg Pathol 2008 Jul;32(7):1060-7. doi: 10.1097/PAS.0b013e318160edaf. PMID: 18496142
Primary prostatic central zone adenocarcinoma.
Mai KT, Belanger EC, Al-Maghrabi HM, Robertson S, Wang D, Margnean C
Pathol Res Pract 2008;204(4):251-8. Epub 2008 Jan 4 doi: 10.1016/j.prp.2007.11.002. PMID: 18178014
Metastatic ductal adenocarcinoma of the prostate: cytologic features and clinical findings.
Gong Y, Caraway N, Stewart J, Staerkel G
Am J Clin Pathol 2006 Aug;126(2):302-9. doi: 10.1309/4TT6-LVJP-QVFW-DB6P. PMID: 16891207

Therapy

The presence and clinical implication of intraductal carcinoma of prostate in metastatic castration resistant prostate cancer.
Chen Z, Chen N, Shen P, Gong J, Li X, Zhao T, Liao B, Liu L, Liu Z, Zhang X, Liu J, Peng Z, Chen X, Xu M, Gui H, Zhang P, Wei Q, Zhou Q, Zeng H
Prostate 2015 Sep;75(12):1247-54. Epub 2015 Apr 27 doi: 10.1002/pros.23005. PMID: 25917338
High-grade prostatic intraepithelial neoplasialike ductal adenocarcinoma of the prostate: a clinicopathologic study of 28 cases.
Tavora F, Epstein JI
Am J Surg Pathol 2008 Jul;32(7):1060-7. doi: 10.1097/PAS.0b013e318160edaf. PMID: 18496142

Prognosis

Comedonecrosis Revisited: Strong Association With Intraductal Carcinoma of the Prostate.
Fine SW, Al-Ahmadie HA, Chen YB, Gopalan A, Tickoo SK, Reuter VE
Am J Surg Pathol 2018 Aug;42(8):1036-1041. doi: 10.1097/PAS.0000000000001104. PMID: 29878934Free PMC Article
The presence and clinical implication of intraductal carcinoma of prostate in metastatic castration resistant prostate cancer.
Chen Z, Chen N, Shen P, Gong J, Li X, Zhao T, Liao B, Liu L, Liu Z, Zhang X, Liu J, Peng Z, Chen X, Xu M, Gui H, Zhang P, Wei Q, Zhou Q, Zeng H
Prostate 2015 Sep;75(12):1247-54. Epub 2015 Apr 27 doi: 10.1002/pros.23005. PMID: 25917338
Intraductal carcinoma of the prostate: interobserver reproducibility survey of 39 urologic pathologists.
Iczkowski KA, Egevad L, Ma J, Harding-Jackson N, Algaba F, Billis A, Camparo P, Cheng L, Clouston D, Comperat EM, Datta MW, Evans AG, Griffiths DF, Guo CC, Hailemariam S, Huang W, Humphrey PA, Jiang Z, Kahane H, Kristiansen G, La Rosa FG, Lopez-Beltran A, MacLennan GT, Magi-Galluzzi C, Merrimen J, Montironi R, Osunkoya AO, Picken MM, Rao N, Shah RB, Shanks JH, Shen SS, Tawfik OW, True LD, Van der Kwast T, Varma M, Wheeler TM, Zynger DL, Sahr N, Bostwick DG
Ann Diagn Pathol 2014 Dec;18(6):333-42. Epub 2014 Sep 3 doi: 10.1016/j.anndiagpath.2014.08.010. PMID: 25263387
Ductal adenocarcinoma of the prostate: current opinion and controversies.
Samaratunga H, Delahunt B
Anal Quant Cytol Histol 2008 Aug;30(4):237-46. PMID: 18773743
Metastatic ductal adenocarcinoma of the prostate: cytologic features and clinical findings.
Gong Y, Caraway N, Stewart J, Staerkel G
Am J Clin Pathol 2006 Aug;126(2):302-9. doi: 10.1309/4TT6-LVJP-QVFW-DB6P. PMID: 16891207

Clinical prediction guides

Comedonecrosis Revisited: Strong Association With Intraductal Carcinoma of the Prostate.
Fine SW, Al-Ahmadie HA, Chen YB, Gopalan A, Tickoo SK, Reuter VE
Am J Surg Pathol 2018 Aug;42(8):1036-1041. doi: 10.1097/PAS.0000000000001104. PMID: 29878934Free PMC Article
Intraductal carcinoma of the prostate: interobserver reproducibility survey of 39 urologic pathologists.
Iczkowski KA, Egevad L, Ma J, Harding-Jackson N, Algaba F, Billis A, Camparo P, Cheng L, Clouston D, Comperat EM, Datta MW, Evans AG, Griffiths DF, Guo CC, Hailemariam S, Huang W, Humphrey PA, Jiang Z, Kahane H, Kristiansen G, La Rosa FG, Lopez-Beltran A, MacLennan GT, Magi-Galluzzi C, Merrimen J, Montironi R, Osunkoya AO, Picken MM, Rao N, Shah RB, Shanks JH, Shen SS, Tawfik OW, True LD, Van der Kwast T, Varma M, Wheeler TM, Zynger DL, Sahr N, Bostwick DG
Ann Diagn Pathol 2014 Dec;18(6):333-42. Epub 2014 Sep 3 doi: 10.1016/j.anndiagpath.2014.08.010. PMID: 25263387
High-grade prostatic intraepithelial neoplasialike ductal adenocarcinoma of the prostate: a clinicopathologic study of 28 cases.
Tavora F, Epstein JI
Am J Surg Pathol 2008 Jul;32(7):1060-7. doi: 10.1097/PAS.0b013e318160edaf. PMID: 18496142
Primary prostatic central zone adenocarcinoma.
Mai KT, Belanger EC, Al-Maghrabi HM, Robertson S, Wang D, Margnean C
Pathol Res Pract 2008;204(4):251-8. Epub 2008 Jan 4 doi: 10.1016/j.prp.2007.11.002. PMID: 18178014
Intraductal carcinoma of the prostate on needle biopsy: Histologic features and clinical significance.
Guo CC, Epstein JI
Mod Pathol 2006 Dec;19(12):1528-35. Epub 2006 Sep 15 doi: 10.1038/modpathol.3800702. PMID: 16980940

Supplemental Content

Table of contents

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...