U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Metastatic Cutaneous Melanoma

MedGen UID:
272113
Concept ID:
C1321872
Neoplastic Process

Definition

A melanoma that arises from the skin and has metastasized to another anatomic site. [from NCI]

Professional guidelines

PubMed

Seth R, Agarwala SS, Messersmith H, Alluri KC, Ascierto PA, Atkins MB, Bollin K, Chacon M, Davis N, Faries MB, Funchain P, Gold JS, Guild S, Gyorki DE, Kaur V, Khushalani NI, Kirkwood JM, McQuade JL, Meyers MO, Provenzano A, Robert C, Santinami M, Sehdev A, Sondak VK, Spurrier G, Swami U, Truong TG, Tsai KK, van Akkooi A, Weber J
J Clin Oncol 2023 Oct 20;41(30):4794-4820. Epub 2023 Aug 14 doi: 10.1200/JCO.23.01136. PMID: 37579248
Patel A, Carr MJ, Sun J, Zager JS
Clin Exp Metastasis 2022 Feb;39(1):201-211. Epub 2021 May 17 doi: 10.1007/s10585-021-10100-3. PMID: 33999365
Amaral T, Meraz-Torres F, Garbe C
Expert Opin Biol Ther 2017 Dec;17(12):1523-1538. Epub 2017 Sep 17 doi: 10.1080/14712598.2017.1378640. PMID: 28891339

Recent clinical studies

Etiology

Maher NG, Vergara IA, Long GV, Scolyer RA
Pathology 2024 Mar;56(2):259-273. Epub 2023 Dec 20 doi: 10.1016/j.pathol.2023.11.004. PMID: 38245478
Cazzato G, Mangialardi K, Falcicchio G, Colagrande A, Ingravallo G, Arezzo F, Giliberti G, Trilli I, Loizzi V, Lettini T, Scarcella S, Annese T, Parente P, Lupo C, Casatta N, Maiorano E, Cormio G, Resta L, Ribatti D
Genes (Basel) 2022 Mar 19;13(3) doi: 10.3390/genes13030545. PMID: 35328098Free PMC Article
Dafni U, Michielin O, Lluesma SM, Tsourti Z, Polydoropoulou V, Karlis D, Besser MJ, Haanen J, Svane IM, Ohashi PS, Kammula US, Orcurto A, Zimmermann S, Trueb L, Klebanoff CA, Lotze MT, Kandalaft LE, Coukos G
Ann Oncol 2019 Dec 1;30(12):1902-1913. doi: 10.1093/annonc/mdz398. PMID: 31566658
Dummer R, Ascierto PA, Gogas HJ, Arance A, Mandala M, Liszkay G, Garbe C, Schadendorf D, Krajsova I, Gutzmer R, Chiarion-Sileni V, Dutriaux C, de Groot JWB, Yamazaki N, Loquai C, Moutouh-de Parseval LA, Pickard MD, Sandor V, Robert C, Flaherty KT
Lancet Oncol 2018 May;19(5):603-615. Epub 2018 Mar 21 doi: 10.1016/S1470-2045(18)30142-6. PMID: 29573941
Pasquali S, Hadjinicolaou AV, Chiarion Sileni V, Rossi CR, Mocellin S
Cochrane Database Syst Rev 2018 Feb 6;2(2):CD011123. doi: 10.1002/14651858.CD011123.pub2. PMID: 29405038Free PMC Article

Diagnosis

Hamid O, Hassel JC, Shoushtari AN, Meier F, Bauer TM, Salama AKS, Kirkwood JM, Ascierto PA, Lorigan PC, Mauch C, Orloff M, Evans TRJ, Holland C, Edukulla R, Abedin SE, Middleton MR
J Immunother Cancer 2023 Jun;11(6) doi: 10.1136/jitc-2023-006747. PMID: 37286303Free PMC Article
Dharanipragada P, Zhang X, Liu S, Lomeli SH, Hong A, Wang Y, Yang Z, Lo KZ, Vega-Crespo A, Ribas A, Moschos SJ, Moriceau G, Lo RS
Cancer Discov 2023 Apr 3;13(4):880-909. doi: 10.1158/2159-8290.CD-22-0787. PMID: 36700848Free PMC Article
Cazzato G, Mangialardi K, Falcicchio G, Colagrande A, Ingravallo G, Arezzo F, Giliberti G, Trilli I, Loizzi V, Lettini T, Scarcella S, Annese T, Parente P, Lupo C, Casatta N, Maiorano E, Cormio G, Resta L, Ribatti D
Genes (Basel) 2022 Mar 19;13(3) doi: 10.3390/genes13030545. PMID: 35328098Free PMC Article
D'Ambrosio AE, Albonico G, Enide I, Mordà O, Maisano M, Mondello B
Ann Thorac Surg 2021 Aug;112(2):e103-e105. Epub 2021 Jan 7 doi: 10.1016/j.athoracsur.2020.09.088. PMID: 33421399
Dafni U, Michielin O, Lluesma SM, Tsourti Z, Polydoropoulou V, Karlis D, Besser MJ, Haanen J, Svane IM, Ohashi PS, Kammula US, Orcurto A, Zimmermann S, Trueb L, Klebanoff CA, Lotze MT, Kandalaft LE, Coukos G
Ann Oncol 2019 Dec 1;30(12):1902-1913. doi: 10.1093/annonc/mdz398. PMID: 31566658

Therapy

Seth R, Agarwala SS, Messersmith H, Alluri KC, Ascierto PA, Atkins MB, Bollin K, Chacon M, Davis N, Faries MB, Funchain P, Gold JS, Guild S, Gyorki DE, Kaur V, Khushalani NI, Kirkwood JM, McQuade JL, Meyers MO, Provenzano A, Robert C, Santinami M, Sehdev A, Sondak VK, Spurrier G, Swami U, Truong TG, Tsai KK, van Akkooi A, Weber J
J Clin Oncol 2023 Oct 20;41(30):4794-4820. Epub 2023 Aug 14 doi: 10.1200/JCO.23.01136. PMID: 37579248
Pham JP, Joshua AM, da Silva IP, Dummer R, Goldinger SM
Curr Oncol Rep 2023 Jun;25(6):609-621. Epub 2023 Mar 29 doi: 10.1007/s11912-023-01385-6. PMID: 36988735Free PMC Article
Middleton MR, McAlpine C, Woodcock VK, Corrie P, Infante JR, Steven NM, Evans TRJ, Anthoney A, Shoushtari AN, Hamid O, Gupta A, Vardeu A, Leach E, Naidoo R, Stanhope S, Lewis S, Hurst J, O'Kelly I, Sznol M
Clin Cancer Res 2020 Nov 15;26(22):5869-5878. Epub 2020 Aug 18 doi: 10.1158/1078-0432.CCR-20-1247. PMID: 32816891Free PMC Article
Dafni U, Michielin O, Lluesma SM, Tsourti Z, Polydoropoulou V, Karlis D, Besser MJ, Haanen J, Svane IM, Ohashi PS, Kammula US, Orcurto A, Zimmermann S, Trueb L, Klebanoff CA, Lotze MT, Kandalaft LE, Coukos G
Ann Oncol 2019 Dec 1;30(12):1902-1913. doi: 10.1093/annonc/mdz398. PMID: 31566658
Dummer R, Ascierto PA, Gogas HJ, Arance A, Mandala M, Liszkay G, Garbe C, Schadendorf D, Krajsova I, Gutzmer R, Chiarion-Sileni V, Dutriaux C, de Groot JWB, Yamazaki N, Loquai C, Moutouh-de Parseval LA, Pickard MD, Sandor V, Robert C, Flaherty KT
Lancet Oncol 2018 May;19(5):603-615. Epub 2018 Mar 21 doi: 10.1016/S1470-2045(18)30142-6. PMID: 29573941

Prognosis

Maher NG, Vergara IA, Long GV, Scolyer RA
Pathology 2024 Mar;56(2):259-273. Epub 2023 Dec 20 doi: 10.1016/j.pathol.2023.11.004. PMID: 38245478
Bertolotto C
C R Biol 2021 Nov 15;344(3):219-231. doi: 10.5802/crbiol.63. PMID: 35786627
Lee S, Suh HB, Choi SJ, Kang J, Kang JW, Kwon EJ, Kim HJ, Kim YH, Shin K
Melanoma Res 2020 Dec;30(6):543-547. doi: 10.1097/CMR.0000000000000697. PMID: 33003118
Francis JH, Berry D, Abramson DH, Barker CA, Bergstrom C, Demirci H, Engelbert M, Grossniklaus H, Hubbard B, Iacob CE, Jaben K, Kurli M, Postow MA, Wolchok JD, Kim IK, Wells JR
Ophthalmology 2020 Feb;127(2):240-248. Epub 2019 Sep 24 doi: 10.1016/j.ophtha.2019.09.018. PMID: 31708274Free PMC Article
Pasquali S, Hadjinicolaou AV, Chiarion Sileni V, Rossi CR, Mocellin S
Cochrane Database Syst Rev 2018 Feb 6;2(2):CD011123. doi: 10.1002/14651858.CD011123.pub2. PMID: 29405038Free PMC Article

Clinical prediction guides

Maher NG, Vergara IA, Long GV, Scolyer RA
Pathology 2024 Mar;56(2):259-273. Epub 2023 Dec 20 doi: 10.1016/j.pathol.2023.11.004. PMID: 38245478
Pavlick AC, Ariyan CE, Buchbinder EI, Davar D, Gibney GT, Hamid O, Hieken TJ, Izar B, Johnson DB, Kulkarni RP, Luke JJ, Mitchell TC, Mooradian MJ, Rubin KM, Salama AK, Shirai K, Taube JM, Tawbi HA, Tolley JK, Valdueza C, Weiss SA, Wong MK, Sullivan RJ
J Immunother Cancer 2023 Oct;11(10) doi: 10.1136/jitc-2023-006947. PMID: 37852736Free PMC Article
Ireland A, Williams B, Rijhumal A, Mesbah Ardakani N
Am J Dermatopathol 2022 Sep 1;44(9):683-686. Epub 2022 Apr 11 doi: 10.1097/DAD.0000000000002199. PMID: 35475788
Middleton MR, McAlpine C, Woodcock VK, Corrie P, Infante JR, Steven NM, Evans TRJ, Anthoney A, Shoushtari AN, Hamid O, Gupta A, Vardeu A, Leach E, Naidoo R, Stanhope S, Lewis S, Hurst J, O'Kelly I, Sznol M
Clin Cancer Res 2020 Nov 15;26(22):5869-5878. Epub 2020 Aug 18 doi: 10.1158/1078-0432.CCR-20-1247. PMID: 32816891Free PMC Article
Francis JH, Berry D, Abramson DH, Barker CA, Bergstrom C, Demirci H, Engelbert M, Grossniklaus H, Hubbard B, Iacob CE, Jaben K, Kurli M, Postow MA, Wolchok JD, Kim IK, Wells JR
Ophthalmology 2020 Feb;127(2):240-248. Epub 2019 Sep 24 doi: 10.1016/j.ophtha.2019.09.018. PMID: 31708274Free PMC Article

Recent systematic reviews

Seth R, Agarwala SS, Messersmith H, Alluri KC, Ascierto PA, Atkins MB, Bollin K, Chacon M, Davis N, Faries MB, Funchain P, Gold JS, Guild S, Gyorki DE, Kaur V, Khushalani NI, Kirkwood JM, McQuade JL, Meyers MO, Provenzano A, Robert C, Santinami M, Sehdev A, Sondak VK, Spurrier G, Swami U, Truong TG, Tsai KK, van Akkooi A, Weber J
J Clin Oncol 2023 Oct 20;41(30):4794-4820. Epub 2023 Aug 14 doi: 10.1200/JCO.23.01136. PMID: 37579248
Cazzato G, Mangialardi K, Falcicchio G, Colagrande A, Ingravallo G, Arezzo F, Giliberti G, Trilli I, Loizzi V, Lettini T, Scarcella S, Annese T, Parente P, Lupo C, Casatta N, Maiorano E, Cormio G, Resta L, Ribatti D
Genes (Basel) 2022 Mar 19;13(3) doi: 10.3390/genes13030545. PMID: 35328098Free PMC Article
Dafni U, Michielin O, Lluesma SM, Tsourti Z, Polydoropoulou V, Karlis D, Besser MJ, Haanen J, Svane IM, Ohashi PS, Kammula US, Orcurto A, Zimmermann S, Trueb L, Klebanoff CA, Lotze MT, Kandalaft LE, Coukos G
Ann Oncol 2019 Dec 1;30(12):1902-1913. doi: 10.1093/annonc/mdz398. PMID: 31566658
Crosby T, Fish R, Coles B, Mason M
Cochrane Database Syst Rev 2018 Feb 7;2(2):CD001215. doi: 10.1002/14651858.CD001215.pub2. PMID: 29411867Free PMC Article
Pasquali S, Hadjinicolaou AV, Chiarion Sileni V, Rossi CR, Mocellin S
Cochrane Database Syst Rev 2018 Feb 6;2(2):CD011123. doi: 10.1002/14651858.CD011123.pub2. PMID: 29405038Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...