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Anus lymphoma

MedGen UID:
272308
Concept ID:
C1332268
Neoplastic Process
Synonyms: Anal Lymphoma; anal lymphoma; anus lymphoma; Lymphoma of anus; Lymphoma of Anus; lymphoma of anus; Lymphoma of the Anus; lymphoma of the anus; Primary Anal Lymphoma; primary anal lymphoma
SNOMED CT: Lymphoma of anus (1153356005)
 
Monarch Initiative: MONDO:0001888

Definition

A usually large cell non-Hodgkin lymphoma of B-cell phenotype, arising from the anus. Lymphomas originating from the anal region are rare in the general population, but they are seen with a higher frequency in HIV-positive patients, particularly homosexual men. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnus lymphoma

Professional guidelines

PubMed

Cuffy M, Abir F, Longo WE
Clin Colorectal Cancer 2006 Jan;5(5):327-37. doi: 10.3816/CCC.2006.n.002. PMID: 16512991

Recent clinical studies

Etiology

Valen H, Becher R, Vist GE, Holme JA, Mdala I, Elvsaas IØ, Alexander J, Underland V, Brinchmann BC, Grimsrud TK
Int J Cancer 2023 Dec 15;153(12):1942-1953. Epub 2023 Jul 21 doi: 10.1002/ijc.34643. PMID: 37480210
Liu MC, Oxnard GR, Klein EA, Swanton C, Seiden MV; CCGA Consortium
Ann Oncol 2020 Jun;31(6):745-759. Epub 2020 Mar 30 doi: 10.1016/j.annonc.2020.02.011. PMID: 33506766Free PMC Article
Hruz P, Juillerat P, Kullak-Ublick GA, Schoepfer AM, Mantzaris GJ, Rogler G; on behalf of Swiss IBDnet, an official working group of the Swiss Society of Gastroenterology
Digestion 2020;101 Suppl 1:105-119. Epub 2020 Jan 14 doi: 10.1159/000503099. PMID: 31935714
Zaorsky NG, Churilla TM, Egleston BL, Fisher SG, Ridge JA, Horwitz EM, Meyer JE
Ann Oncol 2017 Feb 1;28(2):400-407. doi: 10.1093/annonc/mdw604. PMID: 27831506Free PMC Article
Billingsley KG, Stern LE, Lowy AM, Kahlenberg MS, Thomas CR Jr
Surg Oncol Clin N Am 2004 Apr;13(2):375-88. doi: 10.1016/j.soc.2003.12.002. PMID: 15137963

Diagnosis

Liu MC, Oxnard GR, Klein EA, Swanton C, Seiden MV; CCGA Consortium
Ann Oncol 2020 Jun;31(6):745-759. Epub 2020 Mar 30 doi: 10.1016/j.annonc.2020.02.011. PMID: 33506766Free PMC Article
Roy AC, Wattchow D, Astill D, Singh S, Pendlebury S, Gormly K, Segelov E
Surg Oncol Clin N Am 2017 Jan;26(1):143-161. doi: 10.1016/j.soc.2016.07.009. PMID: 27889033
Zaorsky NG, Churilla TM, Egleston BL, Fisher SG, Ridge JA, Horwitz EM, Meyer JE
Ann Oncol 2017 Feb 1;28(2):400-407. doi: 10.1093/annonc/mdw604. PMID: 27831506Free PMC Article
Carbone A, Vaccher E, Gloghini A, Pantanowitz L, Abayomi A, de Paoli P, Franceschi S
Nat Rev Clin Oncol 2014 Apr;11(4):223-38. Epub 2014 Mar 11 doi: 10.1038/nrclinonc.2014.31. PMID: 24614140
Janicke DM, Pundt MR
Emerg Med Clin North Am 1996 Nov;14(4):757-88. doi: 10.1016/s0733-8627(05)70278-9. PMID: 8921768

Therapy

Valen H, Becher R, Vist GE, Holme JA, Mdala I, Elvsaas IØ, Alexander J, Underland V, Brinchmann BC, Grimsrud TK
Int J Cancer 2023 Dec 15;153(12):1942-1953. Epub 2023 Jul 21 doi: 10.1002/ijc.34643. PMID: 37480210
Carbone A, Vaccher E, Gloghini A, Pantanowitz L, Abayomi A, de Paoli P, Franceschi S
Nat Rev Clin Oncol 2014 Apr;11(4):223-38. Epub 2014 Mar 11 doi: 10.1038/nrclinonc.2014.31. PMID: 24614140
Deeken JF, Tjen-A-Looi A, Rudek MA, Okuliar C, Young M, Little RF, Dezube BJ
Clin Infect Dis 2012 Nov;55(9):1228-35. Epub 2012 Jul 9 doi: 10.1093/cid/cis613. PMID: 22776851Free PMC Article
Engels EA
AIDS 2009 May 15;23(8):875-85. doi: 10.1097/QAD.0b013e328329216a. PMID: 19349851Free PMC Article
Billingsley KG, Stern LE, Lowy AM, Kahlenberg MS, Thomas CR Jr
Surg Oncol Clin N Am 2004 Apr;13(2):375-88. doi: 10.1016/j.soc.2003.12.002. PMID: 15137963

Prognosis

Liu MC, Oxnard GR, Klein EA, Swanton C, Seiden MV; CCGA Consortium
Ann Oncol 2020 Jun;31(6):745-759. Epub 2020 Mar 30 doi: 10.1016/j.annonc.2020.02.011. PMID: 33506766Free PMC Article
Hruz P, Juillerat P, Kullak-Ublick GA, Schoepfer AM, Mantzaris GJ, Rogler G; on behalf of Swiss IBDnet, an official working group of the Swiss Society of Gastroenterology
Digestion 2020;101 Suppl 1:105-119. Epub 2020 Jan 14 doi: 10.1159/000503099. PMID: 31935714
Hoff PM, Coudry R, Moniz CM
Surg Oncol Clin N Am 2017 Jan;26(1):57-71. doi: 10.1016/j.soc.2016.07.013. PMID: 27889037
Roy AC, Wattchow D, Astill D, Singh S, Pendlebury S, Gormly K, Segelov E
Surg Oncol Clin N Am 2017 Jan;26(1):143-161. doi: 10.1016/j.soc.2016.07.009. PMID: 27889033
Zaorsky NG, Churilla TM, Egleston BL, Fisher SG, Ridge JA, Horwitz EM, Meyer JE
Ann Oncol 2017 Feb 1;28(2):400-407. doi: 10.1093/annonc/mdw604. PMID: 27831506Free PMC Article

Clinical prediction guides

Castilho JL, Bian A, Jenkins CA, Shepherd BE, Sigel K, Gill MJ, Kitahata MM, Silverberg MJ, Mayor AM, Coburn SB, Wiley D, Achenbach CJ, Marconi VC, Bosch RJ, Horberg MA, Rabkin CS, Napravnik S, Novak RM, Mathews WC, Thorne JE, Sun J, Althoff KN, Moore RD, Sterling TR, Sudenga SL; North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) of the International Epidemiology Databases to Evaluate AIDS (IeDEA)
J Natl Cancer Inst 2022 Jun 13;114(6):854-862. doi: 10.1093/jnci/djac053. PMID: 35292820Free PMC Article
Wu Y, Li Y, Han C, Chong Y, Kang K, Liu Z, Zhang F
Future Oncol 2022 Feb;18(4):445-455. Epub 2022 Jan 12 doi: 10.2217/fon-2021-0332. PMID: 35018785
Liu MC, Oxnard GR, Klein EA, Swanton C, Seiden MV; CCGA Consortium
Ann Oncol 2020 Jun;31(6):745-759. Epub 2020 Mar 30 doi: 10.1016/j.annonc.2020.02.011. PMID: 33506766Free PMC Article
Charifa A, Zhang X
Int J Surg Pathol 2018 Dec;26(8):725-729. Epub 2018 May 14 doi: 10.1177/1066896918773177. PMID: 29759015
Hoff PM, Coudry R, Moniz CM
Surg Oncol Clin N Am 2017 Jan;26(1):57-71. doi: 10.1016/j.soc.2016.07.013. PMID: 27889037

Recent systematic reviews

Martí-Carvajal AJ, Cardona AF, Rodríguez ML
Cochrane Database Syst Rev 2007 Apr 18;(2):CD006149. doi: 10.1002/14651858.CD006149.pub2. PMID: 17443616

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