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Chronic Lymphocytic Leukemia with Plasmacytoid Differentiation

MedGen UID:
272481
Concept ID:
C1333040
Neoplastic Process

Definition

A chronic lymphocytic leukemia characterized by the presence of neoplastic lymphocytes with plasmacytoid morphology. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic Lymphocytic Leukemia with Plasmacytoid Differentiation

Professional guidelines

PubMed

Moore EM, Swerdlow SH, Gibson SE
Am J Surg Pathol 2018 Mar;42(3):342-350. doi: 10.1097/PAS.0000000000001015. PMID: 29309299
Kyle RA, Ansell SM, Kapoor P
Best Pract Res Clin Haematol 2016 Jun;29(2):179-186. Epub 2016 Aug 23 doi: 10.1016/j.beha.2016.08.014. PMID: 27825464Free PMC Article
Liu TY, Chen SU, Kuo SH, Cheng AL, Lin CW
Mod Pathol 2010 Nov;23(11):1507-17. Epub 2010 Aug 27 doi: 10.1038/modpathol.2010.139. PMID: 20802470

Recent clinical studies

Etiology

Kyle RA, Ansell SM, Kapoor P
Best Pract Res Clin Haematol 2016 Jun;29(2):179-186. Epub 2016 Aug 23 doi: 10.1016/j.beha.2016.08.014. PMID: 27825464Free PMC Article
Liu TY, Chen SU, Kuo SH, Cheng AL, Lin CW
Mod Pathol 2010 Nov;23(11):1507-17. Epub 2010 Aug 27 doi: 10.1038/modpathol.2010.139. PMID: 20802470
Shin HJ, Caraway NP, Katz RL
Cancer 2003 Oct 25;99(5):293-300. doi: 10.1002/cncr.11441. PMID: 14579296
Sundeen JT, Longo DL, Jaffe ES
Am J Surg Pathol 1992 Feb;16(2):130-7. doi: 10.1097/00000478-199202000-00005. PMID: 1370753
Harris NL, Bhan AK
Hum Pathol 1985 Aug;16(8):829-37. doi: 10.1016/s0046-8177(85)80255-0. PMID: 3926626

Diagnosis

Khan AM, Munir A, Raval M, Mehdi S
BMJ Case Rep 2019 Jul 15;12(7) doi: 10.1136/bcr-2019-230332. PMID: 31308179Free PMC Article
Kyle RA, Ansell SM, Kapoor P
Best Pract Res Clin Haematol 2016 Jun;29(2):179-186. Epub 2016 Aug 23 doi: 10.1016/j.beha.2016.08.014. PMID: 27825464Free PMC Article
Alley CL, Wang E, Dunphy CH, Gong JZ, Lu CM, Boswell EL, Burchette J, Lagoo AS
Arch Pathol Lab Med 2013 Apr;137(4):503-17. doi: 10.5858/arpa.2011-0696-OA. PMID: 23544940
Elton TS, Selemon H, Elton SM, Parinandi NL
Gene 2013 Dec 10;532(1):1-12. Epub 2012 Dec 14 doi: 10.1016/j.gene.2012.12.009. PMID: 23246696
Asaad NY, Abd El-Wahed MM, Dawoud MM
J Egypt Natl Canc Inst 2005 Dec;17(4):279-90. PMID: 17102815

Therapy

Khan AM, Munir A, Raval M, Mehdi S
BMJ Case Rep 2019 Jul 15;12(7) doi: 10.1136/bcr-2019-230332. PMID: 31308179Free PMC Article
Yin CC, Lin KI, Ketterling RP, Knudson RA, Medeiros LJ, Barron LL, Huh YO, Luthra R, Keating MJ, Abruzzo LV
Am J Clin Pathol 2009 May;131(5):663-70. doi: 10.1309/AJCPXLY46UPFLISC. PMID: 19369625
Gomyo H, Kajimoto K, Maeda A, Mizuno I, Funada Y, Koizumi T, Fukui E, Hanioka K, Ogura M, Murayama T
Hematology 2007 Aug;12(4):315-8. doi: 10.1080/10245330701383866. PMID: 17654058
Pachmann S, Anderegg B, Müller-Höcker J, Nathrath W, Brack N, Tigges FJ, Hartenstein R, Munker R
Am J Hematol 2002 Jun;70(2):167-73. doi: 10.1002/ajh.10104. PMID: 12111792
Mori A, Tamaru J, Sumi H, Kondo H
Eur J Haematol 2002 Apr;68(4):243-6. doi: 10.1034/j.1600-0609.2002.01667.x. PMID: 12071942

Prognosis

Khan AM, Munir A, Raval M, Mehdi S
BMJ Case Rep 2019 Jul 15;12(7) doi: 10.1136/bcr-2019-230332. PMID: 31308179Free PMC Article
Kyle RA, Ansell SM, Kapoor P
Best Pract Res Clin Haematol 2016 Jun;29(2):179-186. Epub 2016 Aug 23 doi: 10.1016/j.beha.2016.08.014. PMID: 27825464Free PMC Article
Jilani I, Wei C, Bekele BN, Zhang ZJ, Keating M, Wierda W, Ferrajoli A, Estrov Z, Kantarjian H, O'Brien SM, Giles FJ, Albitar M
Int J Lab Hematol 2009 Feb;31(1):97-105. Epub 2008 Jan 7 doi: 10.1111/j.1751-553X.2007.01010.x. PMID: 18190591Free PMC Article
Asaad NY, Abd El-Wahed MM, Dawoud MM
J Egypt Natl Canc Inst 2005 Dec;17(4):279-90. PMID: 17102815
Medeiros LJ, Strickler JG, Picker LJ, Gelb AB, Weiss LM, Warnke RA
Am J Pathol 1987 Dec;129(3):523-35. PMID: 3322023Free PMC Article

Clinical prediction guides

Berger F, Traverse-Glehen A, Felman P, Callet-Bauchu E, Baseggio L, Gazzo S, Thieblemont C, Ffrench M, Magaud JP, Salles G, Coiffer B
Clin Lymphoma 2005 Mar;5(4):220-4. doi: 10.3816/clm.2005.n.003. PMID: 15794852
Carlsson M, Matsson P, Rosén A, Sundström C, Tötterman TH, Nilsson K
Leukemia 1988 Nov;2(11):734-44. PMID: 3263557
Medeiros LJ, Strickler JG, Picker LJ, Gelb AB, Weiss LM, Warnke RA
Am J Pathol 1987 Dec;129(3):523-35. PMID: 3322023Free PMC Article
Ostlund L, Einhorn S, Robèrt KH, Juliusson G, Biberfeld P
Blood 1986 Jan;67(1):152-9. PMID: 2416366
Tötterman TH, Nilsson K, Sundström C
Nature 1980 Nov 13;288(5787):176-8. doi: 10.1038/288176a0. PMID: 7432517

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