Colorectal gastrointestinal stromal tumor

MedGen UID:: 272496
•Concept ID:: C1333109
•: Neoplastic Process

Synonyms:	colorectal (colon or rectal) gastrointestinal stromal tumor (gist); colorectal (colon or rectal) gastrointestinal stromal tumour (gist); Colorectal Gastrointestinal Stromal Tumor; colorectal gastrointestinal stromal tumor; colorectal gastrointestinal stromal tumor (gist); colorectal gastrointestinal stromal tumour (gist); Colorectal GIST; colorectal gist

Monarch Initiative:	MONDO:0006159

Definition

A gastrointestinal stromal tumor that arises from the colon or rectum. The majority of cases have spindle cell morphology. Gastrointestinal stromal tumors of the colon are usually advanced upon detection and tend to have a poor prognosis; gastrointestinal stromal tumors of the rectum usually have an aggressive clinical course. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVColorectal gastrointestinal stromal tumor

Disorder of digestive system
- Abnormality of the digestive system
  - Digestive system neoplasm
    - Neoplasm of the gastrointestinal tract
      - Digestive System Soft Tissue Neoplasm
        Gastrointestinal Stromal Tumor of the Gastrointestinal Tract
        Colorectal gastrointestinal stromal tumor

Professional guidelines

PubMed

Evolving role of regorafenib for the treatment of advanced cancers.

Grothey A, Blay JY, Pavlakis N, Yoshino T, Bruix J
Cancer Treat Rev 2020 Jun;86:101993. Epub 2020 Feb 20 doi: 10.1016/j.ctrv.2020.101993. PMID: 32199197

Diagnostic and treatment strategy for small gastrointestinal stromal tumors.

Nishida T, Goto O, Raut CP, Yahagi N
Cancer 2016 Oct 15;122(20):3110-3118. Epub 2016 Aug 1 doi: 10.1002/cncr.30239. PMID: 27478963 Free PMC Article

Contributions of molecular analysis to the diagnosis and treatment of gastrointestinal neoplasms.

Bellizzi AM
Semin Diagn Pathol 2013 Nov;30(4):329-61. Epub 2013 Nov 13 doi: 10.1053/j.semdp.2013.11.001. PMID: 24342289

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