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Conjunctival Squamous Papilloma

MedGen UID:
272507
•Concept ID:
C1333149
•
Neoplastic Process
Synonyms: Conjunctival Squamous Cell Papilloma; Conjunctival squamous papilloma; Pedunculated conjunctival papilloma; Squamous Cell Papilloma of Conjunctiva; Squamous Cell Papilloma of the Conjunctiva
SNOMED CT: Pedunculated conjunctival papilloma (419738008); Conjunctival squamous papilloma (419738008)

Definition

A papilloma that arises from the conjunctival squamous epithelium. It is associated with human papillomavirus infection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVConjunctival Squamous Papilloma

Professional guidelines

PubMed

Conjunctival papilloma treatment outcomes: a 12-year-retrospective study.
Sripawadkul W, Theotoka D, Zein M, Galor A, Karp CL
Eye (Lond) 2023 Apr;37(5):977-982. Epub 2022 Dec 5 doi: 10.1038/s41433-022-02329-3. PMID: 36471167Free PMC Article
Conjunctival squamous intraepithelial neoplasia and its differential diagnosis.
Reese A, Margo CE
J Clin Pathol 2022 May;75(5):354-358. Epub 2021 Feb 22 doi: 10.1136/jclinpath-2020-207302. PMID: 33619216
Human Papillomavirus-Driven Squamous Lesions: High-Risk Genotype Found in Conjunctival Papillomas, Dysplasia, and Carcinoma.
Moyer AB, Roberts J, Olsen RJ, Chévez-Barrios P
Am J Dermatopathol 2018 Jul;40(7):486-490. doi: 10.1097/DAD.0000000000001139. PMID: 29533279

Recent clinical studies

Etiology

Squamous papillomas of the conjunctiva: a retrospective clinicopathological study.
Ogun OA, Ogun GO, Bekibele CO, Akang EE
Niger J Clin Pract 2012 Jan-Mar;15(1):89-92. doi: 10.4103/1119-3077.94106. PMID: 22437098
Different types of conjunctival papilloma presenting in the same eye.
Kalantzis G, Papaconstantinou D, Georgalas I, Tsitlidou A, Georgopoulos G
Orbit 2010 Oct;29(5):266-8. Epub 2010 Aug 16 doi: 10.3109/01676831003739707. PMID: 20712514

Diagnosis

Ocular rhinosporidiosis mimicking conjunctival squamous papilloma in Kenya - a case report.
Gichuhi S, Onyuma T, Macharia E, Kabiru J, Zindamoyen AM, Sagoo MS, Burton MJ
BMC Ophthalmol 2014 Apr 8;14:45. doi: 10.1186/1471-2415-14-45. PMID: 24708655Free PMC Article
Squamous papillomas of the conjunctiva: a retrospective clinicopathological study.
Ogun OA, Ogun GO, Bekibele CO, Akang EE
Niger J Clin Pract 2012 Jan-Mar;15(1):89-92. doi: 10.4103/1119-3077.94106. PMID: 22437098

Therapy

Successful Treatment of Exuberant Conjunctival Squamous Papilloma.
Eldeeb M, Hegazy O, Chan EW
JAMA Ophthalmol 2020 Feb 1;138(2):e190930. Epub 2020 Feb 13 doi: 10.1001/jamaophthalmol.2019.0930. PMID: 32053177
Long-term administration of topical interferon alfa-2beta in the treatment of conjunctival squamous papilloma.
Morgenstern KE, Givan J, Wiley LA
Arch Ophthalmol 2003 Jul;121(7):1052-3. doi: 10.1001/archopht.121.7.1052. PMID: 12860816

Prognosis

Different types of conjunctival papilloma presenting in the same eye.
Kalantzis G, Papaconstantinou D, Georgalas I, Tsitlidou A, Georgopoulos G
Orbit 2010 Oct;29(5):266-8. Epub 2010 Aug 16 doi: 10.3109/01676831003739707. PMID: 20712514

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