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EBV-Related Non-Hodgkin Lymphoma

MedGen UID:: 272583
•Concept ID:: C1333433
•: Neoplastic Process

Synonyms:

EBV Related Non-Hodgkin's Lymphoma; EBV-Related Non-Hodgkin's Lymphoma; Epstein-Barr Virus Related Non-Hodgkin's Lymphoma; Epstein-Barr Virus-Related Non-Hodgkin Lymphoma; Epstein-Barr Virus-Related Non-Hodgkin's Lymphoma

Definition

Non-Hodgkin lymphoma that is caused by Epstein-Barr virus infection. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVEBV-Related Non-Hodgkin Lymphoma

Neoplasm by Cause
- Infection-Related Neoplasm
  - Infection-Related Malignant Neoplasm
    - Virus-Related Malignant Neoplasm
      - EBV-Related Malignant Neoplasm
        EBV-Related Lymphoma
        EBV-Related Non-Hodgkin Lymphoma
        EBV-Related Burkitt Lymphoma
        Endemic Burkitt Lymphoma
        Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly
        Recurrent EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
        Refractory EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
        Grade III lymphomatoid granulomatosis
        Adult Grade III Lymphomatoid Granulomatosis
        Recurrent Adult Grade III Lymphomatoid Granulomatosis
        Childhood Grade III Lymphomatoid Granulomatosis
        Recurrent Childhood Grade III Lymphomatoid Granulomatosis
        Recurrent Grade III Lymphomatoid Granulomatosis
        Primary EBV-Positive Nodal T-Cell or NK-Cell Lymphoma
        Systemic EBV-Positive T-Cell Lymphoma of Childhood

Professional guidelines

PubMed

Current Treatment Options for Older Patients with Hodgkin Lymphoma.

Carter J, David KA, Kritharis A, Evens AM
Curr Treat Options Oncol 2020 Apr 23;21(5):42. doi: 10.1007/s11864-020-00745-9. PMID: 32328822

In situ hybridisation for Epstein-Barr virus as a differential diagnostic tool for T- and natural killer/T-cell lymphomas in non-immunocompromised patients.

Chuang SS
Pathology 2014 Dec;46(7):581-91. doi: 10.1097/PAT.0000000000000161. PMID: 25393247

Virus-specific cytotoxic CD4+ T cells for the treatment of EBV-related tumors.

Merlo A, Turrini R, Bobisse S, Zamarchi R, Alaggio R, Dolcetti R, Mautner J, Zanovello P, Amadori A, Rosato A
J Immunol 2010 May 15;184(10):5895-902. Epub 2010 Apr 12 doi: 10.4049/jimmunol.0902850. PMID: 20385879

See all (4)

Recent clinical studies

Etiology

What we should know about natural killer/T-cell lymphomas.

Xiong J, Zhao W
Hematol Oncol 2019 Jun;37 Suppl 1:75-81. doi: 10.1002/hon.2588. PMID: 31187536

Epstein-Barr Virus (EBV)-Related Lymphoproliferative Disorders in Ataxia Telangiectasia: Does ATM Regulate EBV Life Cycle?

Tatfi M, Hermine O, Suarez F
Front Immunol 2018;9:3060. Epub 2019 Jan 4 doi: 10.3389/fimmu.2018.03060. PMID: 30662441 Free PMC Article

Human immunodeficiency virus (HIV) and Epstein-Barr virus (EBV) related lymphomas, pathology view point.

Linke-Serinsöz E, Fend F, Quintanilla-Martinez L
Semin Diagn Pathol 2017 Jul;34(4):352-363. Epub 2017 Apr 7 doi: 10.1053/j.semdp.2017.04.003. PMID: 28506687

Angiocentric and intravascular lymphomas.

Tomasini D, Berti E
G Ital Dermatol Venereol 2015 Feb;150(1):95-113. Epub 2014 Dec 22 PMID: 25531150

Epstein-Barr virus vaccines.

Morgan AJ
Vaccine 1992;10(9):563-71. doi: 10.1016/0264-410x(92)90434-l. PMID: 1323899

See all (71)

Diagnosis

Haemophagocytic lymphohistiocytosis and Epstein-Barr virus: a complex relationship with diverse origins, expression and outcomes.

El-Mallawany NK, Curry CV, Allen CE
Br J Haematol 2022 Jan;196(1):31-44. Epub 2021 Jun 24 doi: 10.1111/bjh.17638. PMID: 34169507

NK-/T-cell lymphomas.

Wang H, Fu BB, Gale RP, Liang Y
Leukemia 2021 Sep;35(9):2460-2468. Epub 2021 Jun 11 doi: 10.1038/s41375-021-01313-2. PMID: 34117356 Free PMC Article

What we should know about natural killer/T-cell lymphomas.

Xiong J, Zhao W
Hematol Oncol 2019 Jun;37 Suppl 1:75-81. doi: 10.1002/hon.2588. PMID: 31187536

Primary CNS lymphoma in HIV infection.

Brandsma D, Bromberg JEC
Handb Clin Neurol 2018;152:177-186. doi: 10.1016/B978-0-444-63849-6.00014-1. PMID: 29604975

Angiocentric and intravascular lymphomas.

Tomasini D, Berti E
G Ital Dermatol Venereol 2015 Feb;150(1):95-113. Epub 2014 Dec 22 PMID: 25531150

See all (89)

Therapy

Estimating the global burden of Epstein-Barr virus-related cancers.

Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104 Free PMC Article

NK-/T-cell lymphomas.

Wang H, Fu BB, Gale RP, Liang Y
Leukemia 2021 Sep;35(9):2460-2468. Epub 2021 Jun 11 doi: 10.1038/s41375-021-01313-2. PMID: 34117356 Free PMC Article

NK/T-cell lymphomas.

Tse E, Kwong YL
Best Pract Res Clin Haematol 2019 Sep;32(3):253-261. Epub 2019 Jun 12 doi: 10.1016/j.beha.2019.06.005. PMID: 31585625

Novel Therapeutics for Epstein⁻Barr Virus.

Andrei G, Trompet E, Snoeck R
Molecules 2019 Mar 12;24(5) doi: 10.3390/molecules24050997. PMID: 30871092 Free PMC Article

Primary CNS lymphoma in HIV infection.

Brandsma D, Bromberg JEC
Handb Clin Neurol 2018;152:177-186. doi: 10.1016/B978-0-444-63849-6.00014-1. PMID: 29604975

See all (67)

Prognosis

NK-/T-cell lymphomas.

Wang H, Fu BB, Gale RP, Liang Y
Leukemia 2021 Sep;35(9):2460-2468. Epub 2021 Jun 11 doi: 10.1038/s41375-021-01313-2. PMID: 34117356 Free PMC Article

What we should know about natural killer/T-cell lymphomas.

Xiong J, Zhao W
Hematol Oncol 2019 Jun;37 Suppl 1:75-81. doi: 10.1002/hon.2588. PMID: 31187536

Epstein-Barr Virus (EBV)-Related Lymphoproliferative Disorders in Ataxia Telangiectasia: Does ATM Regulate EBV Life Cycle?

Tatfi M, Hermine O, Suarez F
Front Immunol 2018;9:3060. Epub 2019 Jan 4 doi: 10.3389/fimmu.2018.03060. PMID: 30662441 Free PMC Article

Primary CNS lymphoma in HIV infection.

Brandsma D, Bromberg JEC
Handb Clin Neurol 2018;152:177-186. doi: 10.1016/B978-0-444-63849-6.00014-1. PMID: 29604975

Angiocentric and intravascular lymphomas.

Tomasini D, Berti E
G Ital Dermatol Venereol 2015 Feb;150(1):95-113. Epub 2014 Dec 22 PMID: 25531150

See all (64)

Clinical prediction guides

Estimating the global burden of Epstein-Barr virus-related cancers.

Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104 Free PMC Article

NK-/T-cell lymphomas.

Wang H, Fu BB, Gale RP, Liang Y
Leukemia 2021 Sep;35(9):2460-2468. Epub 2021 Jun 11 doi: 10.1038/s41375-021-01313-2. PMID: 34117356 Free PMC Article

What we should know about natural killer/T-cell lymphomas.

Xiong J, Zhao W
Hematol Oncol 2019 Jun;37 Suppl 1:75-81. doi: 10.1002/hon.2588. PMID: 31187536

Human immunodeficiency virus (HIV) and Epstein-Barr virus (EBV) related lymphomas, pathology view point.

Linke-Serinsöz E, Fend F, Quintanilla-Martinez L
Semin Diagn Pathol 2017 Jul;34(4):352-363. Epub 2017 Apr 7 doi: 10.1053/j.semdp.2017.04.003. PMID: 28506687

Epstein-Barr virus (EBV)-associated lymphoid lesions of the head and neck.

Auerbach A, Aguilera NS
Semin Diagn Pathol 2015 Jan;32(1):12-22. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2014.12.001. PMID: 25804341

See all (44)

Recent systematic reviews

EBV Positivity and Programmed Death-ligand 1 Expression in Diffuse Large B-cell Lymphoma: A Systematic Review.

Barzyk GA, Sheriff V
Anticancer Res 2020 Nov;40(11):5951-5968. doi: 10.21873/anticanres.14616. PMID: 33109533

See all (1)

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EBV-Related Non-Hodgkin Lymphoma

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

Recent activity