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Grade 1 Invasive Breast Carcinoma

MedGen UID:
272673
•Concept ID:
C1333832
•
Neoplastic Process
Synonyms: Favorable Infiltrating Breast Carcinoma; Grade 1 Infiltrating Breast Carcinoma; Low Combined Histologic Grade Infiltrating Breast Carcinoma; Well Differentiated Infiltrating Breast Carcinoma; Well Differentiated Invasive Breast Carcinoma

Definition

A well differentiated invasive breast carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 1 Invasive Breast Carcinoma

Professional guidelines

PubMed

Subclassifying triple-negative breast cancers and its potential clinical utility.
Lian J, Ma HX, Xu EW, Bu P, Yun KM, Xi YF
Virchows Arch 2022 Jul;481(1):13-21. Epub 2022 Apr 26 doi: 10.1007/s00428-022-03329-0. PMID: 35471664
Early primary breast cancer in the elderly - pattern of presentation and treatment.
Tang SW, Parker H, Winterbottom L, Hassell K, Ellis IO, Morgan DA, Cheung KL
Surg Oncol 2011 Mar;20(1):7-12. Epub 2009 Aug 12 doi: 10.1016/j.suronc.2009.07.004. PMID: 19679464
The management of ductal carcinoma in situ of the breast.
Skinner KA, Silverstein MJ
Endocr Relat Cancer 2001 Mar;8(1):33-45. doi: 10.1677/erc.0.0080033. PMID: 11350725

Recent clinical studies

Etiology

Nucleolus assessment in invasive breast carcinoma, an objective parameter for histological grading.
Öztürk SD, Öztürk Ç, Okcu O, Şen B, Bedir R
Turk J Med Sci 2022 Aug;52(4):975-983. Epub 2022 Aug 10 doi: 10.55730/1300-0144.5398. PMID: 36326384Free PMC Article
Asprosin and meteorin-like protein immunoreactivity in invasive ductal breast carcinoma stages.
Akkus G, Koyuturk LC, Yilmaz M, Hancer S, Ozercan IH, Kuloglu T
Tissue Cell 2022 Aug;77:101855. Epub 2022 Jun 17 doi: 10.1016/j.tice.2022.101855. PMID: 35749857
CD8+ TILS Expression in Invasive Breast Carcinoma (No Special Type).
Astuti A, Miskad UA, Arsyadi G, Zainuddin AA, Wahid S, Nelwan BJ
Asian Pac J Cancer Prev 2022 May 1;23(5):1813-1816. doi: 10.31557/APJCP.2022.23.5.1813. PMID: 35633568Free PMC Article
Grading of invasive breast carcinoma: the way forward.
van Dooijeweert C, van Diest PJ, Ellis IO
Virchows Arch 2022 Jan;480(1):33-43. Epub 2021 Jul 1 doi: 10.1007/s00428-021-03141-2. PMID: 34196797Free PMC Article
The histopathological and molecular features of breast carcinoma with tumour budding-a systematic review and meta-analysis.
Lloyd AJ, Ryan ÉJ, Boland MR, Elwahab SA, Malone C, Sweeney KJ, Barry KM, McLaughlin R, Kerin MJ, Lowery AJ
Breast Cancer Res Treat 2020 Oct;183(3):503-514. Epub 2020 Jul 24 doi: 10.1007/s10549-020-05810-3. PMID: 32710280

Diagnosis

Nucleolus assessment in invasive breast carcinoma, an objective parameter for histological grading.
Öztürk SD, Öztürk Ç, Okcu O, Şen B, Bedir R
Turk J Med Sci 2022 Aug;52(4):975-983. Epub 2022 Aug 10 doi: 10.55730/1300-0144.5398. PMID: 36326384Free PMC Article
Invasive lobular carcinoma of the breast: the increasing importance of this special subtype.
McCart Reed AE, Kalinowski L, Simpson PT, Lakhani SR
Breast Cancer Res 2021 Jan 7;23(1):6. doi: 10.1186/s13058-020-01384-6. PMID: 33413533Free PMC Article
Microglandular Adenosis and Associated Invasive Carcinoma.
Kravtsov O, Jorns JM
Arch Pathol Lab Med 2020 Jan;144(1):42-46. Epub 2019 May 22 doi: 10.5858/arpa.2019-0049-RA. PMID: 31116044
Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics.
McCart Reed AE, Kutasovic JR, Lakhani SR, Simpson PT
Breast Cancer Res 2015 Jan 30;17(1):12. doi: 10.1186/s13058-015-0519-x. PMID: 25849106Free PMC Article
Lobular breast carcinoma and its variants.
Rakha EA, Ellis IO
Semin Diagn Pathol 2010 Feb;27(1):49-61. doi: 10.1053/j.semdp.2009.12.009. PMID: 20306830

Therapy

Mammographic density, endocrine therapy and breast cancer risk: a prognostic and predictive biomarker review.
Atakpa EC, Thorat MA, Cuzick J, Brentnall AR
Cochrane Database Syst Rev 2021 Oct 26;10(10):CD013091. doi: 10.1002/14651858.CD013091.pub2. PMID: 34697802Free PMC Article
Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial.
Vicini FA, Cecchini RS, White JR, Arthur DW, Julian TB, Rabinovitch RA, Kuske RR, Ganz PA, Parda DS, Scheier MF, Winter KA, Paik S, Kuerer HM, Vallow LA, Pierce LJ, Mamounas EP, McCormick B, Costantino JP, Bear HD, Germain I, Gustafson G, Grossheim L, Petersen IA, Hudes RS, Curran WJ Jr, Bryant JL, Wolmark N
Lancet 2019 Dec 14;394(10215):2155-2164. Epub 2019 Dec 5 doi: 10.1016/S0140-6736(19)32514-0. PMID: 31813636Free PMC Article
Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial.
Coles CE, Griffin CL, Kirby AM, Titley J, Agrawal RK, Alhasso A, Bhattacharya IS, Brunt AM, Ciurlionis L, Chan C, Donovan EM, Emson MA, Harnett AN, Haviland JS, Hopwood P, Jefford ML, Kaggwa R, Sawyer EJ, Syndikus I, Tsang YM, Wheatley DA, Wilcox M, Yarnold JR, Bliss JM; IMPORT Trialists
Lancet 2017 Sep 9;390(10099):1048-1060. Epub 2017 Aug 2 doi: 10.1016/S0140-6736(17)31145-5. PMID: 28779963Free PMC Article
Overweight, Obesity, and Postmenopausal Invasive Breast Cancer Risk: A Secondary Analysis of the Women's Health Initiative Randomized Clinical Trials.
Neuhouser ML, Aragaki AK, Prentice RL, Manson JE, Chlebowski R, Carty CL, Ochs-Balcom HM, Thomson CA, Caan BJ, Tinker LF, Urrutia RP, Knudtson J, Anderson GL
JAMA Oncol 2015 Aug;1(5):611-21. doi: 10.1001/jamaoncol.2015.1546. PMID: 26182172Free PMC Article
Breast-conserving surgery with or without irradiation in women aged 65 years or older with early breast cancer (PRIME II): a randomised controlled trial.
Kunkler IH, Williams LJ, Jack WJ, Cameron DA, Dixon JM; PRIME II investigators
Lancet Oncol 2015 Mar;16(3):266-73. Epub 2015 Jan 28 doi: 10.1016/S1470-2045(14)71221-5. PMID: 25637340

Prognosis

The Incidence of Breast Cancer After Gender-Affirming Mastectomy in Transmen.
Parmeshwar N, Song S, Alcon A, Kim EA
Ann Plast Surg 2022 May 1;88(4 Suppl 4):S332-S336. Epub 2022 Feb 21 doi: 10.1097/SAP.0000000000003083. PMID: 35180758
Measuring Invasive Breast Carcinoma on Core Biopsy-Is It Necessary?
Liang Y, Oza T, Corben A, Zeizafoun N, Alexander M, Jaffer S
Arch Pathol Lab Med 2021 Nov 1;145(11):1432-1437. doi: 10.5858/arpa.2020-0287-OA. PMID: 33503224
Encapsulated papillary carcinoma of breast; a clinicopathological study of 25 cases and literature review with emphasis on high grade variant.
Tariq MU, Idress R, Qureshi MB, Kayani N
Ann Diagn Pathol 2020 Dec;49:151613. Epub 2020 Aug 28 doi: 10.1016/j.anndiagpath.2020.151613. PMID: 32911448
Roles and correlation of FOXA1 and ZIC1 in breast cancer.
Zhang YW, Ma J, Shi CT, Han W, Gao XJ, Zhou MH, Ding HZ, Wang HN
Curr Probl Cancer 2020 Oct;44(5):100559. Epub 2020 Feb 21 doi: 10.1016/j.currproblcancer.2020.100559. PMID: 32115254
Invasive Lobular Breast Carcinoma: Pleomorphic Versus Classical Subtype, Associations and Prognosis.
Liu YL, Choi C, Lee SM, Zhong X, Hibshoosh H, Kalinsky K, Connolly EP
Clin Breast Cancer 2018 Apr;18(2):114-120. Epub 2017 Jun 23 doi: 10.1016/j.clbc.2017.06.006. PMID: 28720418

Clinical prediction guides

Nucleolus assessment in invasive breast carcinoma, an objective parameter for histological grading.
Öztürk SD, Öztürk Ç, Okcu O, Şen B, Bedir R
Turk J Med Sci 2022 Aug;52(4):975-983. Epub 2022 Aug 10 doi: 10.55730/1300-0144.5398. PMID: 36326384Free PMC Article
Measuring Invasive Breast Carcinoma on Core Biopsy-Is It Necessary?
Liang Y, Oza T, Corben A, Zeizafoun N, Alexander M, Jaffer S
Arch Pathol Lab Med 2021 Nov 1;145(11):1432-1437. doi: 10.5858/arpa.2020-0287-OA. PMID: 33503224
Microglandular adenosis of the breast: a deceptive and still mysterious benign lesion.
Foschini MP, Eusebi V
Hum Pathol 2018 Dec;82:1-9. Epub 2018 Jun 24 doi: 10.1016/j.humpath.2018.06.025. PMID: 29949742
Invasive Lobular Breast Carcinoma: Pleomorphic Versus Classical Subtype, Associations and Prognosis.
Liu YL, Choi C, Lee SM, Zhong X, Hibshoosh H, Kalinsky K, Connolly EP
Clin Breast Cancer 2018 Apr;18(2):114-120. Epub 2017 Jun 23 doi: 10.1016/j.clbc.2017.06.006. PMID: 28720418
Invasive lobular breast cancer and its variants: how special are they for systemic therapy decisions?
Guiu S, Wolfer A, Jacot W, Fumoleau P, Romieu G, Bonnetain F, Fiche M
Crit Rev Oncol Hematol 2014 Dec;92(3):235-57. Epub 2014 Jul 30 doi: 10.1016/j.critrevonc.2014.07.003. PMID: 25129506

Recent systematic reviews

Breast cancer prognosis and P-cadherin expression: systematic review and study-level meta-analysis.
Qi R, Lin J, Chen S, Jiang J, Zhang X, Yao B, Zheng H, Jin Z, Yuan Y, Hou W, Hua B, Guo Q
BMJ Support Palliat Care 2022 Dec;12(e6):e893-e905. Epub 2020 Sep 17 doi: 10.1136/bmjspcare-2020-002204. PMID: 32943470
Partial breast irradiation versus whole breast radiotherapy for early breast cancer.
Hickey BE, Lehman M
Cochrane Database Syst Rev 2021 Aug 30;8(8):CD007077. doi: 10.1002/14651858.CD007077.pub4. PMID: 34459500Free PMC Article
The histopathological and molecular features of breast carcinoma with tumour budding-a systematic review and meta-analysis.
Lloyd AJ, Ryan ÉJ, Boland MR, Elwahab SA, Malone C, Sweeney KJ, Barry KM, McLaughlin R, Kerin MJ, Lowery AJ
Breast Cancer Res Treat 2020 Oct;183(3):503-514. Epub 2020 Jul 24 doi: 10.1007/s10549-020-05810-3. PMID: 32710280
Breast cancer in elderly women and altered clinico-pathological characteristics: a systematic review.
Lodi M, Scheer L, Reix N, Heitz D, Carin AJ, Thiébaut N, Neuberger K, Tomasetto C, Mathelin C
Breast Cancer Res Treat 2017 Dec;166(3):657-668. Epub 2017 Aug 12 doi: 10.1007/s10549-017-4448-5. PMID: 28803352
Ductal carcinoma in situ of the breast: a systematic review of incidence, treatment, and outcomes.
Virnig BA, Tuttle TM, Shamliyan T, Kane RL
J Natl Cancer Inst 2010 Feb 3;102(3):170-8. Epub 2010 Jan 13 doi: 10.1093/jnci/djp482. PMID: 20071685

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