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Intracranial Lipoma

MedGen UID:
272768
•Concept ID:
C1334241
•
Neoplastic Process

Definition

A rare benign adipose tissue neoplasm located in the intracranial region. It is a congenital hamartomatous malformation derived from the embryologic meninx primitiva. [from NCI]

Professional guidelines

PubMed

Prenatal diagnosis and postnatal follow-up of pericallosal lipoma: report of seven new cases.
Ickowitz V, Eurin D, Rypens F, Sonigo P, Simon I, David P, Brunelle F, Avni FE
AJNR Am J Neuroradiol 2001 Apr;22(4):767-72. PMID: 11290497Free PMC Article
Prenatal ultrasonographic diagnosis of fetal intracranial tumors: a review.
Sherer DM, Onyeije CI
Am J Perinatol 1998 May;15(5):319-28. doi: 10.1055/s-2007-993951. PMID: 9643639
Intracranial lipomas: current perspectives in their diagnosis and treatment.
Eghwrudjakpor PO, Kurisaka M, Fukuoka M, Mori K
Br J Neurosurg 1992;6(2):139-44. doi: 10.3109/02688699209002916. PMID: 1590967

Recent clinical studies

Etiology

The clinical and radiological features of cisternal and pericallosal lipomas.
Taydas O, Ogul H, Kantarci M
Acta Neurol Belg 2020 Feb;120(1):65-70. Epub 2019 Mar 13 doi: 10.1007/s13760-019-01119-1. PMID: 30868467
Incidental intracranial lipomas: Assessment of 163 patients.
Türk O , Yaldiz C
Ideggyogy Sz 2019 Mar 30;72(3-4):89-92. doi: 10.18071/isz.72.0089. PMID: 30957462
Intracranial lipomas: clinical and imaging findings.
Karakaş E, Doğan MS, Çullu N, Kocatürk M, Kocatürk Ö, Karakaş Ö, Celik B, Boyaci FN
Clin Ter 2014;165(2):e134-8. doi: 10.7471/CT.2014.1696. PMID: 24770821
Intracranial lipomas: importance of localization.
Yildiz H, Hakyemez B, Koroglu M, Yesildag A, Baykal B
Neuroradiology 2006 Jan;48(1):1-7. Epub 2005 Oct 20 doi: 10.1007/s00234-005-0001-z. PMID: 16237548
Parietal lipomeningocele--case report.
Yamashita S, Kunishio K, Tamiya T, Nakamura T, Ogawa D, Igawa HH, Kuroda Y, Nagao S
Neurol Med Chir (Tokyo) 2005 Feb;45(2):112-5. doi: 10.2176/nmc.45.112. PMID: 15722612

Diagnosis

The clinical and radiological features of cisternal and pericallosal lipomas.
Taydas O, Ogul H, Kantarci M
Acta Neurol Belg 2020 Feb;120(1):65-70. Epub 2019 Mar 13 doi: 10.1007/s13760-019-01119-1. PMID: 30868467
Incidental intracranial lipomas: Assessment of 163 patients.
Türk O , Yaldiz C
Ideggyogy Sz 2019 Mar 30;72(3-4):89-92. doi: 10.18071/isz.72.0089. PMID: 30957462
Intracranial lipomas: clinical and imaging findings.
Karakaş E, Doğan MS, Çullu N, Kocatürk M, Kocatürk Ö, Karakaş Ö, Celik B, Boyaci FN
Clin Ter 2014;165(2):e134-8. doi: 10.7471/CT.2014.1696. PMID: 24770821
Parietal lipomeningocele--case report.
Yamashita S, Kunishio K, Tamiya T, Nakamura T, Ogawa D, Igawa HH, Kuroda Y, Nagao S
Neurol Med Chir (Tokyo) 2005 Feb;45(2):112-5. doi: 10.2176/nmc.45.112. PMID: 15722612
Pathogenesis of intracranial lipoma: an MR study in 42 patients.
Truwit CL, Barkovich AJ
AJR Am J Roentgenol 1990 Oct;155(4):855-64; discussion 865. doi: 10.2214/ajr.155.4.2119122. PMID: 2119122

Therapy

A case of Wilson's disease combined with intracranial lipoma and dysplasia of the corpus callosum with review of the literature.
Zhang L, Zhu L, Ci C, Ai W, Wang Y, Wang X
BMC Neurol 2024 Jan 25;24(1):44. doi: 10.1186/s12883-024-03541-2. PMID: 38273263Free PMC Article
Epilepsy surgery without lipoma removal for temporal lobe epilepsy associated with lipoma in the Sylvian fissure.
Nomura K, Suzuki H, Iimura Y, Mitsuhashi T, Tamrakar S, Ueda T, Nishioka K, Fusegi K, Tada M, Nakajima M, Kakita A, Sugano H
Acta Neurochir (Wien) 2023 Jan;165(1):265-269. Epub 2022 Aug 8 doi: 10.1007/s00701-022-05330-7. PMID: 35934751Free PMC Article
Encephalocraniocutaneous lipomatosis: A case report with review of literature.
Siddiqui S, Naaz S, Ahmad M, Khan ZA, Wahab S, Rashid BA
Neuroradiol J 2017 Dec;30(6):578-582. Epub 2017 Jul 14 doi: 10.1177/1971400917693638. PMID: 28707961Free PMC Article
Interpeduncular fossa lipoma: a novel cause of oculomotor nerve palsy in childhood.
Malone JR, Bogie A, Crittenden-Byers C
Pediatr Emerg Care 2012 Feb;28(2):160-2. doi: 10.1097/PEC.0b013e3182447716. PMID: 22307184
Sturge-Weber syndrome accompanied with multiple congenital intracranial lesions.
Ergün R, Okten AI, Gezercan Y, Gezici AR
Acta Neurochir (Wien) 2007 Aug;149(8):829-30; discussion 830. Epub 2007 Aug 1 doi: 10.1007/s00701-007-1224-z. PMID: 17660941

Prognosis

A case of Wilson's disease combined with intracranial lipoma and dysplasia of the corpus callosum with review of the literature.
Zhang L, Zhu L, Ci C, Ai W, Wang Y, Wang X
BMC Neurol 2024 Jan 25;24(1):44. doi: 10.1186/s12883-024-03541-2. PMID: 38273263Free PMC Article
Mental Development and Surgical Prognosis of Pai Syndrome: A Case Report and Review of the Literature.
Imai Y, Kure S, Nara C, Takagi N, Tachi M
Cleft Palate Craniofac J 2019 Feb;56(2):273-279. Epub 2018 Apr 17 doi: 10.1177/1055665618771419. PMID: 29665340
Giant intracranial lipoma.
Tubbs RS, Louis RG Jr, Loukas M, Shoja MM, Blount JP
Folia Neuropathol 2007;45(4):247-9. PMID: 18176900
Parietal lipomeningocele--case report.
Yamashita S, Kunishio K, Tamiya T, Nakamura T, Ogawa D, Igawa HH, Kuroda Y, Nagao S
Neurol Med Chir (Tokyo) 2005 Feb;45(2):112-5. doi: 10.2176/nmc.45.112. PMID: 15722612
Pathogenesis of intracranial lipoma: an MR study in 42 patients.
Truwit CL, Barkovich AJ
AJR Am J Roentgenol 1990 Oct;155(4):855-64; discussion 865. doi: 10.2214/ajr.155.4.2119122. PMID: 2119122

Clinical prediction guides

Intracranial lipomas: clinical and imaging findings.
Karakaş E, Doğan MS, Çullu N, Kocatürk M, Kocatürk Ö, Karakaş Ö, Celik B, Boyaci FN
Clin Ter 2014;165(2):e134-8. doi: 10.7471/CT.2014.1696. PMID: 24770821
Craniofacial features resembling frontonasal dysplasia with a tubulonodular interhemispheric lipoma in the adult 3H1 tuft mouse.
Fong KS, Cooper TB, Drumhiller WC, Somponpun SJ, Yang S, Ernst T, Chang L, Lozanoff S
Birth Defects Res A Clin Mol Teratol 2012 Feb;94(2):102-13. Epub 2012 Jan 13 doi: 10.1002/bdra.22878. PMID: 22246904Free PMC Article
Interhemispheric lipoma associated with frontal subcutaneous lipoma.
Mitilian D, Haddad D, Lenoir M, Boudjemaa S, Vazquez MP, Picard A
J Plast Reconstr Aesthet Surg 2009 Nov;62(11):e427-9. Epub 2008 Nov 17 doi: 10.1016/j.bjps.2008.06.072. PMID: 19010104
Intracranial lipomas: importance of localization.
Yildiz H, Hakyemez B, Koroglu M, Yesildag A, Baykal B
Neuroradiology 2006 Jan;48(1):1-7. Epub 2005 Oct 20 doi: 10.1007/s00234-005-0001-z. PMID: 16237548
Intracranial chemical-shift artifacts on MR images of the brain: observations and relation to sampling bandwidth.
Smith AS, Weinstein MA, Hurst GC, DeRemer DR, Cole RA, Duchesneau PM
AJR Am J Roentgenol 1990 Jun;154(6):1275-83. doi: 10.2214/ajr.154.6.2110742. PMID: 2110742

Recent systematic reviews

Central nervous system anomalies in craniofacial microsomia: a systematic review.
Renkema RW, Caron CJJM, Wolvius EB, Dunaway DJ, Forrest CR, Padwa BL, Koudstaal MJ
Int J Oral Maxillofac Surg 2018 Jan;47(1):27-34. Epub 2017 Jul 20 doi: 10.1016/j.ijom.2017.06.009. PMID: 28736116

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