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Cancer Cell Growth Regulation

MedGen UID:
273062
•Concept ID:
C1516171
•
Neoplastic Process

Definition

Control of the rate or manner of occurrence of the complex series of phenomena occurring after division and before death of cancer cells. (NCI) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCancer Cell Growth Regulation

Professional guidelines

PubMed

Elranatamab: a new promising BispAb in multiple myeloma treatment.
Grosicki S, Bednarczyk M, Kociszewska K
Expert Rev Anticancer Ther 2023 Jul-Dec;23(8):775-782. Epub 2023 Jul 20 doi: 10.1080/14737140.2023.2236303. PMID: 37434334
Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway.
Kurppa KJ, Liu Y, To C, Zhang T, Fan M, Vajdi A, Knelson EH, Xie Y, Lim K, Cejas P, Portell A, Lizotte PH, Ficarro SB, Li S, Chen T, Haikala HM, Wang H, Bahcall M, Gao Y, Shalhout S, Boettcher S, Shin BH, Thai T, Wilkens MK, Tillgren ML, Mushajiang M, Xu M, Choi J, Bertram AA, Ebert BL, Beroukhim R, Bandopadhayay P, Awad MM, Gokhale PC, Kirschmeier PT, Marto JA, Camargo FD, Haq R, Paweletz CP, Wong KK, Barbie DA, Long HW, Gray NS, Jänne PA
Cancer Cell 2020 Jan 13;37(1):104-122.e12. doi: 10.1016/j.ccell.2019.12.006. PMID: 31935369Free PMC Article
Consensus guidelines for the use and interpretation of angiogenesis assays.
Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW
Angiogenesis 2018 Aug;21(3):425-532. doi: 10.1007/s10456-018-9613-x. PMID: 29766399Free PMC Article

Recent clinical studies

Etiology

The role of intratumoral and systemic IL-6 in breast cancer.
Dethlefsen C, Højfeldt G, Hojman P
Breast Cancer Res Treat 2013 Apr;138(3):657-64. Epub 2013 Mar 27 doi: 10.1007/s10549-013-2488-z. PMID: 23532539

Diagnosis

Orphan nuclear receptor estrogen-related receptor-beta suppresses in vitro and in vivo growth of prostate cancer cells via p21(WAF1/CIP1) induction and as a potential therapeutic target in prostate cancer.
Yu S, Wong YC, Wang XH, Ling MT, Ng CF, Chen S, Chan FL
Oncogene 2008 May 22;27(23):3313-28. Epub 2007 Dec 10 doi: 10.1038/sj.onc.1210986. PMID: 18071305

Therapy

Orphan nuclear receptor estrogen-related receptor-beta suppresses in vitro and in vivo growth of prostate cancer cells via p21(WAF1/CIP1) induction and as a potential therapeutic target in prostate cancer.
Yu S, Wong YC, Wang XH, Ling MT, Ng CF, Chen S, Chan FL
Oncogene 2008 May 22;27(23):3313-28. Epub 2007 Dec 10 doi: 10.1038/sj.onc.1210986. PMID: 18071305

Prognosis

MiR-22-3p Regulates Cell Proliferation and Inhibits Cell Apoptosis through Targeting the eIF4EBP3 Gene in Human Cervical Squamous Carcinoma Cells.
Lv KT, Liu Z, Feng J, Zhao W, Hao T, Ding WY, Chu JP, Gao LJ
Int J Med Sci 2018;15(2):142-152. Epub 2018 Jan 1 doi: 10.7150/ijms.21645. PMID: 29333098Free PMC Article
Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer.
Börnigen D, Tyekucheva S, Wang X, Rider JR, Lee GS, Mucci LA, Sweeney C, Huttenhower C
PLoS Comput Biol 2016 Apr;12(4):e1004820. Epub 2016 Apr 14 doi: 10.1371/journal.pcbi.1004820. PMID: 27078000Free PMC Article
The role of intratumoral and systemic IL-6 in breast cancer.
Dethlefsen C, Højfeldt G, Hojman P
Breast Cancer Res Treat 2013 Apr;138(3):657-64. Epub 2013 Mar 27 doi: 10.1007/s10549-013-2488-z. PMID: 23532539
Transfection of human ovarian cancer cells with the HER-2/neu receptor tyrosine kinase induces a selective increase in PTP-H1, PTP-1B, PTP-alpha expression.
Wiener JR, Kassim SK, Yu Y, Mills GB, Bast RC Jr
Gynecol Oncol 1996 May;61(2):233-40. doi: 10.1006/gyno.1996.0131. PMID: 8626139

Clinical prediction guides

MiR-22-3p Regulates Cell Proliferation and Inhibits Cell Apoptosis through Targeting the eIF4EBP3 Gene in Human Cervical Squamous Carcinoma Cells.
Lv KT, Liu Z, Feng J, Zhao W, Hao T, Ding WY, Chu JP, Gao LJ
Int J Med Sci 2018;15(2):142-152. Epub 2018 Jan 1 doi: 10.7150/ijms.21645. PMID: 29333098Free PMC Article
Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer.
Börnigen D, Tyekucheva S, Wang X, Rider JR, Lee GS, Mucci LA, Sweeney C, Huttenhower C
PLoS Comput Biol 2016 Apr;12(4):e1004820. Epub 2016 Apr 14 doi: 10.1371/journal.pcbi.1004820. PMID: 27078000Free PMC Article

Supplemental Content

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    Practice guidelines

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