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Clonal Evolution

MedGen UID:
273181
•Concept ID:
C1516669
•
Neoplastic Process
Synonym: Evolution, Clonal

Definition

The process by which a normal cell accumulates genetic changes that allow it to become a tumor-causing cell and furthers its development to more malignant states. [from NCI]

Professional guidelines

PubMed

Changing paradigms in diagnosis and treatment of monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM).
Ho M, Patel A, Goh CY, Moscvin M, Zhang L, Bianchi G
Leukemia 2020 Dec;34(12):3111-3125. Epub 2020 Oct 12 doi: 10.1038/s41375-020-01051-x. PMID: 33046818
Treatment of Relapsed Acute Myeloid Leukemia.
Thol F, Ganser A
Curr Treat Options Oncol 2020 Jun 29;21(8):66. doi: 10.1007/s11864-020-00765-5. PMID: 32601974Free PMC Article
Mantle cell lymphoma: 2019 update on the diagnosis, pathogenesis, prognostication, and management.
Jain P, Wang M
Am J Hematol 2019 Jun;94(6):710-725. Epub 2019 Apr 19 doi: 10.1002/ajh.25487. PMID: 30963600

Recent clinical studies

Etiology

Modern management of Fanconi anemia.
Dufour C, Pierri F
Hematology Am Soc Hematol Educ Program 2022 Dec 9;2022(1):649-657. doi: 10.1182/hematology.2022000393. PMID: 36485157Free PMC Article
Roadmap to cure multiple myeloma.
Rodriguez-Otero P, Paiva B, San-Miguel JF
Cancer Treat Rev 2021 Nov;100:102284. Epub 2021 Aug 31 doi: 10.1016/j.ctrv.2021.102284. PMID: 34597912
Clonal hematopoiesis and nonhematologic disorders.
Jaiswal S
Blood 2020 Oct 1;136(14):1606-1614. doi: 10.1182/blood.2019000989. PMID: 32736379Free PMC Article
Cardiovascular Disease, Aging, and Clonal Hematopoiesis.
Evans MA, Sano S, Walsh K
Annu Rev Pathol 2020 Jan 24;15:419-438. Epub 2019 Nov 5 doi: 10.1146/annurev-pathmechdis-012419-032544. PMID: 31689371Free PMC Article
Multiple Myeloma Genomics - A Concise Review.
Castaneda O, Baz R
Acta Med Acad 2019 Apr;48(1):57-67. doi: 10.5644/ama2006-124.242. PMID: 31264433

Diagnosis

Yersinia pestis: the Natural History of Plague.
Barbieri R, Signoli M, Chevé D, Costedoat C, Tzortzis S, Aboudharam G, Raoult D, Drancourt M
Clin Microbiol Rev 2020 Dec 16;34(1) Epub 2020 Dec 9 doi: 10.1128/CMR.00044-19. PMID: 33298527Free PMC Article
Multiple Myeloma Genomics - A Concise Review.
Castaneda O, Baz R
Acta Med Acad 2019 Apr;48(1):57-67. doi: 10.5644/ama2006-124.242. PMID: 31264433
Tumour heterogeneity and resistance to cancer therapies.
Dagogo-Jack I, Shaw AT
Nat Rev Clin Oncol 2018 Feb;15(2):81-94. Epub 2017 Nov 8 doi: 10.1038/nrclinonc.2017.166. PMID: 29115304
Genetic Basis of Acute Lymphoblastic Leukemia.
Iacobucci I, Mullighan CG
J Clin Oncol 2017 Mar 20;35(9):975-983. Epub 2017 Feb 13 doi: 10.1200/JCO.2016.70.7836. PMID: 28297628Free PMC Article
Measuring cancer evolution from the genome.
Graham TA, Sottoriva A
J Pathol 2017 Jan;241(2):183-191. Epub 2016 Nov 18 doi: 10.1002/path.4821. PMID: 27741350

Therapy

Modern management of Fanconi anemia.
Dufour C, Pierri F
Hematology Am Soc Hematol Educ Program 2022 Dec 9;2022(1):649-657. doi: 10.1182/hematology.2022000393. PMID: 36485157Free PMC Article
Genetics of progression from MDS to secondary leukemia.
Menssen AJ, Walter MJ
Blood 2020 Jul 2;136(1):50-60. doi: 10.1182/blood.2019000942. PMID: 32430504Free PMC Article
Leukemia secondary to myeloproliferative neoplasms.
Dunbar AJ, Rampal RK, Levine R
Blood 2020 Jul 2;136(1):61-70. doi: 10.1182/blood.2019000943. PMID: 32430500Free PMC Article
Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer.
Leonetti A, Sharma S, Minari R, Perego P, Giovannetti E, Tiseo M
Br J Cancer 2019 Oct;121(9):725-737. Epub 2019 Sep 30 doi: 10.1038/s41416-019-0573-8. PMID: 31564718Free PMC Article
Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab.
Riaz N, Havel JJ, Makarov V, Desrichard A, Urba WJ, Sims JS, Hodi FS, Martín-Algarra S, Mandal R, Sharfman WH, Bhatia S, Hwu WJ, Gajewski TF, Slingluff CL Jr, Chowell D, Kendall SM, Chang H, Shah R, Kuo F, Morris LGT, Sidhom JW, Schneck JP, Horak CE, Weinhold N, Chan TA
Cell 2017 Nov 2;171(4):934-949.e16. Epub 2017 Oct 12 doi: 10.1016/j.cell.2017.09.028. PMID: 29033130Free PMC Article

Prognosis

Genetics of progression from MDS to secondary leukemia.
Menssen AJ, Walter MJ
Blood 2020 Jul 2;136(1):50-60. doi: 10.1182/blood.2019000942. PMID: 32430504Free PMC Article
Cardiovascular Disease, Aging, and Clonal Hematopoiesis.
Evans MA, Sano S, Walsh K
Annu Rev Pathol 2020 Jan 24;15:419-438. Epub 2019 Nov 5 doi: 10.1146/annurev-pathmechdis-012419-032544. PMID: 31689371Free PMC Article
Multiple Myeloma Genomics - A Concise Review.
Castaneda O, Baz R
Acta Med Acad 2019 Apr;48(1):57-67. doi: 10.5644/ama2006-124.242. PMID: 31264433
Tumour heterogeneity and resistance to cancer therapies.
Dagogo-Jack I, Shaw AT
Nat Rev Clin Oncol 2018 Feb;15(2):81-94. Epub 2017 Nov 8 doi: 10.1038/nrclinonc.2017.166. PMID: 29115304
Measuring cancer evolution from the genome.
Graham TA, Sottoriva A
J Pathol 2017 Jan;241(2):183-191. Epub 2016 Nov 18 doi: 10.1002/path.4821. PMID: 27741350

Clinical prediction guides

Deterministic evolution and stringent selection during preneoplasia.
Karlsson K, Przybilla MJ, Kotler E, Khan A, Xu H, Karagyozova K, Sockell A, Wong WH, Liu K, Mah A, Lo YH, Lu B, Houlahan KE, Ma Z, Suarez CJ, Barnes CP, Kuo CJ, Curtis C
Nature 2023 Jun;618(7964):383-393. Epub 2023 May 31 doi: 10.1038/s41586-023-06102-8. PMID: 37258665Free PMC Article
Intratumoral heterogeneity and clonal evolution in liver cancer.
Losic B, Craig AJ, Villacorta-Martin C, Martins-Filho SN, Akers N, Chen X, Ahsen ME, von Felden J, Labgaa I, DʹAvola D, Allette K, Lira SA, Furtado GC, Garcia-Lezana T, Restrepo P, Stueck A, Ward SC, Fiel MI, Hiotis SP, Gunasekaran G, Sia D, Schadt EE, Sebra R, Schwartz M, Llovet JM, Thung S, Stolovitzky G, Villanueva A
Nat Commun 2020 Jan 15;11(1):291. doi: 10.1038/s41467-019-14050-z. PMID: 31941899Free PMC Article
Cardiovascular Disease, Aging, and Clonal Hematopoiesis.
Evans MA, Sano S, Walsh K
Annu Rev Pathol 2020 Jan 24;15:419-438. Epub 2019 Nov 5 doi: 10.1146/annurev-pathmechdis-012419-032544. PMID: 31689371Free PMC Article
Multiple Myeloma Genomics - A Concise Review.
Castaneda O, Baz R
Acta Med Acad 2019 Apr;48(1):57-67. doi: 10.5644/ama2006-124.242. PMID: 31264433
Measuring cancer evolution from the genome.
Graham TA, Sottoriva A
J Pathol 2017 Jan;241(2):183-191. Epub 2016 Nov 18 doi: 10.1002/path.4821. PMID: 27741350

Recent systematic reviews

Response to therapy in Richter syndrome: a systematic review with meta-analysis of early clinical trials.
Sousa-Pimenta M, Martins Â, Mariz JM, Berraondo P
Front Immunol 2023;14:1295293. Epub 2023 Nov 23 doi: 10.3389/fimmu.2023.1295293. PMID: 38077330Free PMC Article
Head and neck cancer with synchronous nodules of the lung as a diagnostic and therapeutic challenge - A systematic review.
Müller M, Li J, Giger R, Elicin O
Oral Oncol 2023 Oct;145:106529. Epub 2023 Jul 26 doi: 10.1016/j.oraloncology.2023.106529. PMID: 37506514
Evolutionary perspectives, heterogeneity and ovarian cancer: a complicated tale from past to present.
Achimas-Cadariu P, Kubelac P, Irimie A, Berindan-Neagoe I, Rühli F
J Ovarian Res 2022 Jun 3;15(1):67. doi: 10.1186/s13048-022-01004-1. PMID: 35659345Free PMC Article
A Systematic Review of Prostate Cancer Heterogeneity: Understanding the Clonal Ancestry of Multifocal Disease.
Erickson A, Hayes A, Rajakumar T, Verrill C, Bryant RJ, Hamdy FC, Wedge DC, Woodcock DJ, Mills IG, Lamb AD
Eur Urol Oncol 2021 Jun;4(3):358-369. Epub 2021 Apr 20 doi: 10.1016/j.euo.2021.02.008. PMID: 33888445
The Risk of Clonal Evolution of Granulocyte Colony-Stimulating Factor for Acquired Aplastic Anemia: A Systematic Review and Meta-Analysis.
Ding SX, Chen T, Wang T, Liu CY, Lu WL, Fu R
Acta Haematol 2018;140(3):141-145. Epub 2018 Sep 25 doi: 10.1159/000491816. PMID: 30253387

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