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Gain of Chromosome 18

MedGen UID:
273358
•Concept ID:
C1517396
•
Cell or Molecular Dysfunction

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGain of Chromosome 18

Professional guidelines

PubMed

aCGH on chorionic villi mirrors the complexity of fetoplacental mosaicism in prenatal diagnosis.
Filges I, Kang A, Klug V, Wenzel F, Heinimann K, Tercanli S, Miny P
Prenat Diagn 2011 May;31(5):473-8. Epub 2011 Feb 24 doi: 10.1002/pd.2721. PMID: 21351283

Recent clinical studies

Etiology

Different patterns of chromosomal imbalances in metastasising and non-metastasising primary breast carcinomas.
Adeyinka A, Mertens F, Idvall I, Bondeson L, Ingvar C, Mitelman F, Pandis N
Int J Cancer 1999 Aug 20;84(4):370-5. doi: 10.1002/(sici)1097-0215(19990820)84:4<370::aid-ijc7>3.0.co;2-7. PMID: 10404088

Diagnosis

Establishment and characterization of a new activated B-cell-like DLBCL cell line, TMD12.
Nagao T, Yoshifuji K, Sadato D, Motomura Y, Saito M, Yamamoto K, Yamamoto K, Nogami A
Exp Hematol 2022 Dec;116:37-49. Epub 2022 Oct 1 doi: 10.1016/j.exphem.2022.09.005. PMID: 36191884
Detection of an Underlying 22q11.2 Duplication in a Female Neonate With Trisomy 18.
Turbiville DE, Wu H, Dong J
Lab Med 2017 Nov 8;48(4):372-375. doi: 10.1093/labmed/lmx039. PMID: 29036626Free PMC Article
Prognostic relevance of CD163 and CD8 combined with EZH2 and gain of chromosome 18 in follicular lymphoma: a study by the Lunenburg Lymphoma Biomarker Consortium.
Stevens WBC, Mendeville M, Redd R, Clear AJ, Bladergroen R, Calaminici M, Rosenwald A, Hoster E, Hiddemann W, Gaulard P, Xerri L, Salles G, Klapper W, Pfreundschuh M, Jack A, Gascoyne RD, Natkunam Y, Advani R, Kimby E, Sander B, Sehn LH, Hagenbeek A, Raemaekers J, Gribben J, Kersten MJ, Ylstra B, Weller E, de Jong D
Haematologica 2017 Aug;102(8):1413-1423. Epub 2017 Apr 14 doi: 10.3324/haematol.2017.165415. PMID: 28411252Free PMC Article
Intravascular large B-cell lymphoma manifesting as cholecystitis: report of an Asian variant showing gain of chromosome 18 with concurrent deletion of chromosome 6q.
Tajima S, Waki M, Yamazaki H, Nagata Y, Fukano H, Hossen MA, Hoshi S, Takeuchi T
Int J Clin Exp Pathol 2014;7(11):8181-9. Epub 2014 Oct 15 PMID: 25550870Free PMC Article
Double-minute chromatin bodies in HL-60 leukemia cells sensitive and resistant to differentiation inducing agents.
Schwartsmann G, Madan K, Heins Y, Pinedo HM, Leyva A
Cell Biol Int Rep 1987 Sep;11(9):651-5. doi: 10.1016/0309-1651(87)90099-3. PMID: 3479266

Therapy

Prognostic relevance of CD163 and CD8 combined with EZH2 and gain of chromosome 18 in follicular lymphoma: a study by the Lunenburg Lymphoma Biomarker Consortium.
Stevens WBC, Mendeville M, Redd R, Clear AJ, Bladergroen R, Calaminici M, Rosenwald A, Hoster E, Hiddemann W, Gaulard P, Xerri L, Salles G, Klapper W, Pfreundschuh M, Jack A, Gascoyne RD, Natkunam Y, Advani R, Kimby E, Sander B, Sehn LH, Hagenbeek A, Raemaekers J, Gribben J, Kersten MJ, Ylstra B, Weller E, de Jong D
Haematologica 2017 Aug;102(8):1413-1423. Epub 2017 Apr 14 doi: 10.3324/haematol.2017.165415. PMID: 28411252Free PMC Article

Prognosis

Establishment and characterization of a new activated B-cell-like DLBCL cell line, TMD12.
Nagao T, Yoshifuji K, Sadato D, Motomura Y, Saito M, Yamamoto K, Yamamoto K, Nogami A
Exp Hematol 2022 Dec;116:37-49. Epub 2022 Oct 1 doi: 10.1016/j.exphem.2022.09.005. PMID: 36191884
Prognostic relevance of CD163 and CD8 combined with EZH2 and gain of chromosome 18 in follicular lymphoma: a study by the Lunenburg Lymphoma Biomarker Consortium.
Stevens WBC, Mendeville M, Redd R, Clear AJ, Bladergroen R, Calaminici M, Rosenwald A, Hoster E, Hiddemann W, Gaulard P, Xerri L, Salles G, Klapper W, Pfreundschuh M, Jack A, Gascoyne RD, Natkunam Y, Advani R, Kimby E, Sander B, Sehn LH, Hagenbeek A, Raemaekers J, Gribben J, Kersten MJ, Ylstra B, Weller E, de Jong D
Haematologica 2017 Aug;102(8):1413-1423. Epub 2017 Apr 14 doi: 10.3324/haematol.2017.165415. PMID: 28411252Free PMC Article

Clinical prediction guides

Prognostic relevance of CD163 and CD8 combined with EZH2 and gain of chromosome 18 in follicular lymphoma: a study by the Lunenburg Lymphoma Biomarker Consortium.
Stevens WBC, Mendeville M, Redd R, Clear AJ, Bladergroen R, Calaminici M, Rosenwald A, Hoster E, Hiddemann W, Gaulard P, Xerri L, Salles G, Klapper W, Pfreundschuh M, Jack A, Gascoyne RD, Natkunam Y, Advani R, Kimby E, Sander B, Sehn LH, Hagenbeek A, Raemaekers J, Gribben J, Kersten MJ, Ylstra B, Weller E, de Jong D
Haematologica 2017 Aug;102(8):1413-1423. Epub 2017 Apr 14 doi: 10.3324/haematol.2017.165415. PMID: 28411252Free PMC Article
Intravascular large B-cell lymphoma manifesting as cholecystitis: report of an Asian variant showing gain of chromosome 18 with concurrent deletion of chromosome 6q.
Tajima S, Waki M, Yamazaki H, Nagata Y, Fukano H, Hossen MA, Hoshi S, Takeuchi T
Int J Clin Exp Pathol 2014;7(11):8181-9. Epub 2014 Oct 15 PMID: 25550870Free PMC Article
Loss and gain of chromosomes 1, 18, and Y in prostate cancer.
König JJ, Teubel W, van Dongen JW, Romijn JC, Hagemeijer A, Schröder FH
Prostate 1994 Dec;25(6):281-91. doi: 10.1002/pros.2990250602. PMID: 7527913

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