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Gain of Chromosome 19

MedGen UID:
273359
•Concept ID:
C1517398
•
Cell or Molecular Dysfunction

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGain of Chromosome 19

Professional guidelines

PubMed

Exploring the molecular pathogenesis, diagnosis and treatment of fibrolamellar hepatocellular carcinoma: A state of art review of the current literature.
Alshareefy Y, Shen CY, Prekash RJ
Pathol Res Pract 2023 Aug;248:154655. Epub 2023 Jun 26 doi: 10.1016/j.prp.2023.154655. PMID: 37429175
Baseline characteristics, chromosomal alterations, and treatment affecting prognosis of deletion 17p in newly diagnosed myeloma.
Merz M, Hielscher T, Seckinger A, Hose D, Mai EK, Raab MS, Goldschmidt H, Jauch A, Hillengass J
Am J Hematol 2016 Nov;91(11):E473-E477. Epub 2016 Sep 3 doi: 10.1002/ajh.24533. PMID: 27508939
Association of chromosome 19 to lung cancer genotypes and phenotypes.
Wang X, Zhang Y, Nilsson CL, Berven FS, Andrén PE, Carlsohn E, Horvatovich P, Malm J, Fuentes M, Végvári Á, Welinder C, Fehniger TE, Rezeli M, Edula G, Hober S, Nishimura T, Marko-Varga G
Cancer Metastasis Rev 2015 Jun;34(2):217-26. doi: 10.1007/s10555-015-9556-2. PMID: 25982285

Recent clinical studies

Etiology

Integrated multiomics analysis of chromosome 19 miRNA cluster in bladder cancer.
Ware AP, Satyamoorthy K, Paul B
Funct Integr Genomics 2023 Aug 5;23(3):266. doi: 10.1007/s10142-023-01191-0. PMID: 37542643Free PMC Article
Accuracy and applications of sequencing and genotyping approaches for CYP2A6 and homologous genes.
Langlois AWR, El-Boraie A, Fukunaga K, Mushiroda T, Kubo M, Lerman C, Knight J, Scherer SE, Chenoweth MJ, Tyndale RF
Pharmacogenet Genomics 2022 Jun 1;32(4):159-172. Epub 2022 Feb 21 doi: 10.1097/FPC.0000000000000466. PMID: 35190513Free PMC Article
MRI Imaging Characteristics of Glioblastoma with Concurrent Gain of Chromosomes 19 and 20.
Min TL, Allen JW, Velazquez Vega JE, Neill SG, Weinberg BD
Tomography 2021 Jun 2;7(2):228-237. doi: 10.3390/tomography7020021. PMID: 34199376Free PMC Article
Distribution of segmental chromosomal alterations in neuroblastoma.
Juan Ribelles A, Gargallo P, Ferriol C, Segura V, Yáñez Y, Juan B, Cañada AJ, Font de Mora J, Cañete A, Castel V
Clin Transl Oncol 2021 Jun;23(6):1096-1104. Epub 2020 Sep 18 doi: 10.1007/s12094-020-02497-2. PMID: 32948984
Identification and characterization of Aurora kinase B and C variants associated with maternal aneuploidy.
Nguyen AL, Marin D, Zhou A, Gentilello AS, Smoak EM, Cao Z, Fedick A, Wang Y, Taylor D, Scott RT Jr, Xing J, Treff N, Schindler K
Mol Hum Reprod 2017 Jun 1;23(6):406-416. doi: 10.1093/molehr/gax018. PMID: 28369513Free PMC Article

Diagnosis

Integrated multiomics analysis of chromosome 19 miRNA cluster in bladder cancer.
Ware AP, Satyamoorthy K, Paul B
Funct Integr Genomics 2023 Aug 5;23(3):266. doi: 10.1007/s10142-023-01191-0. PMID: 37542643Free PMC Article
Exploring the molecular pathogenesis, diagnosis and treatment of fibrolamellar hepatocellular carcinoma: A state of art review of the current literature.
Alshareefy Y, Shen CY, Prekash RJ
Pathol Res Pract 2023 Aug;248:154655. Epub 2023 Jun 26 doi: 10.1016/j.prp.2023.154655. PMID: 37429175
The oligodendroglial histological features are not independently predictive of patient prognosis in lower-grade gliomas.
Pareira ES, Shibuya M, Ohara K, Nakagawa Y, Kanazawa T, Kamamoto D, Kato Y, Arai E, Aimono E, Yoshida K, Nishihara H, Kanai Y, Sasaki H
Brain Tumor Pathol 2022 Apr;39(2):79-87. Epub 2022 Mar 15 doi: 10.1007/s10014-022-00426-5. PMID: 35292862
Overcoming the Odds: Toward a Molecular Profile of Long-Term Survival in Glioblastoma.
Richardson TE, Kumar A, Xing C, Hatanpaa KJ, Walker JM
J Neuropathol Exp Neurol 2020 Oct 1;79(10):1031-1037. doi: 10.1093/jnen/nlaa102. PMID: 32954439
Clinical value of chromosome arms 19q and 11p losses in low-grade gliomas.
Alentorn A, van Thuijl HF, Marie Y, Alshehhi H, Carpentier C, Boisselier B, Laigle-Donadey F, Mokhtari K, Scheinin I, Wesseling P, Ylstra B, Capelle L, Hoang-Xuan K, Sanson M, Delattre JY, Reijneveld JC, Idbaih A
Neuro Oncol 2014 Mar;16(3):400-8. Epub 2013 Dec 12 doi: 10.1093/neuonc/not227. PMID: 24335697Free PMC Article

Therapy

Germline PRKACA amplification-associated primary pigmented nodular adrenocortical disease: a case report and literature review.
Yang WR, Liang XH, Qin YF, Yang HY, He SZ, Huang ZX, Liu YP, Luo ZJ
Arch Endocrinol Metab 2023 Nov 17;68:e220491. doi: 10.20945/2359-4292-2022-0491. PMID: 37988664Free PMC Article
Recurrent oligodendroglioma with changed 1p/19q status.
Barresi V, Mafficini A, Calicchia M, Piredda ML, Musumeci A, Ghimenton C, Scarpa A
Neuropathology 2022 Apr;42(2):160-166. Epub 2022 Feb 10 doi: 10.1111/neup.12789. PMID: 35144313Free PMC Article
Distribution of segmental chromosomal alterations in neuroblastoma.
Juan Ribelles A, Gargallo P, Ferriol C, Segura V, Yáñez Y, Juan B, Cañada AJ, Font de Mora J, Cañete A, Castel V
Clin Transl Oncol 2021 Jun;23(6):1096-1104. Epub 2020 Sep 18 doi: 10.1007/s12094-020-02497-2. PMID: 32948984
Whole genome and biomarker analysis of patients with recurrent glioblastoma on bevacizumab: A subset analysis of the CABARET trial.
Olafson LR, Siddell AH, Field KM, Byrnes M, Rapkins RW, Ng B, Nixdorf S, Barnes EH, Johns TG, Yip S, Simes J, Nowak AK, Rosenthal MA, McDonald KL
J Clin Neurosci 2019 Dec;70:157-163. Epub 2019 Sep 30 doi: 10.1016/j.jocn.2019.08.044. PMID: 31582283
Relationship between chromatin structure, DNA damage and repair following X-irradiation of human lymphocytes.
Mosesso P, Palitti F, Pepe G, Piñero J, Bellacima R, Ahnstrom G, Natarajan AT
Mutat Res 2010 Aug 14;701(1):86-91. Epub 2010 Mar 16 doi: 10.1016/j.mrgentox.2010.03.005. PMID: 20298805

Prognosis

Integrated multiomics analysis of chromosome 19 miRNA cluster in bladder cancer.
Ware AP, Satyamoorthy K, Paul B
Funct Integr Genomics 2023 Aug 5;23(3):266. doi: 10.1007/s10142-023-01191-0. PMID: 37542643Free PMC Article
The oligodendroglial histological features are not independently predictive of patient prognosis in lower-grade gliomas.
Pareira ES, Shibuya M, Ohara K, Nakagawa Y, Kanazawa T, Kamamoto D, Kato Y, Arai E, Aimono E, Yoshida K, Nishihara H, Kanai Y, Sasaki H
Brain Tumor Pathol 2022 Apr;39(2):79-87. Epub 2022 Mar 15 doi: 10.1007/s10014-022-00426-5. PMID: 35292862
MRI Imaging Characteristics of Glioblastoma with Concurrent Gain of Chromosomes 19 and 20.
Min TL, Allen JW, Velazquez Vega JE, Neill SG, Weinberg BD
Tomography 2021 Jun 2;7(2):228-237. doi: 10.3390/tomography7020021. PMID: 34199376Free PMC Article
Distribution of segmental chromosomal alterations in neuroblastoma.
Juan Ribelles A, Gargallo P, Ferriol C, Segura V, Yáñez Y, Juan B, Cañada AJ, Font de Mora J, Cañete A, Castel V
Clin Transl Oncol 2021 Jun;23(6):1096-1104. Epub 2020 Sep 18 doi: 10.1007/s12094-020-02497-2. PMID: 32948984
Overcoming the Odds: Toward a Molecular Profile of Long-Term Survival in Glioblastoma.
Richardson TE, Kumar A, Xing C, Hatanpaa KJ, Walker JM
J Neuropathol Exp Neurol 2020 Oct 1;79(10):1031-1037. doi: 10.1093/jnen/nlaa102. PMID: 32954439

Clinical prediction guides

Exploring the molecular pathogenesis, diagnosis and treatment of fibrolamellar hepatocellular carcinoma: A state of art review of the current literature.
Alshareefy Y, Shen CY, Prekash RJ
Pathol Res Pract 2023 Aug;248:154655. Epub 2023 Jun 26 doi: 10.1016/j.prp.2023.154655. PMID: 37429175
The oligodendroglial histological features are not independently predictive of patient prognosis in lower-grade gliomas.
Pareira ES, Shibuya M, Ohara K, Nakagawa Y, Kanazawa T, Kamamoto D, Kato Y, Arai E, Aimono E, Yoshida K, Nishihara H, Kanai Y, Sasaki H
Brain Tumor Pathol 2022 Apr;39(2):79-87. Epub 2022 Mar 15 doi: 10.1007/s10014-022-00426-5. PMID: 35292862
Distribution of segmental chromosomal alterations in neuroblastoma.
Juan Ribelles A, Gargallo P, Ferriol C, Segura V, Yáñez Y, Juan B, Cañada AJ, Font de Mora J, Cañete A, Castel V
Clin Transl Oncol 2021 Jun;23(6):1096-1104. Epub 2020 Sep 18 doi: 10.1007/s12094-020-02497-2. PMID: 32948984
Systematically characterize the clinical and biological significances of 1p19q genes in 1p/19q non-codeletion glioma.
Chai RC, Zhang KN, Chang YZ, Wu F, Liu YQ, Zhao Z, Wang KY, Chang YH, Jiang T, Wang YZ
Carcinogenesis 2019 Oct 16;40(10):1229-1239. doi: 10.1093/carcin/bgz102. PMID: 31157866
Identification and characterization of Aurora kinase B and C variants associated with maternal aneuploidy.
Nguyen AL, Marin D, Zhou A, Gentilello AS, Smoak EM, Cao Z, Fedick A, Wang Y, Taylor D, Scott RT Jr, Xing J, Treff N, Schindler K
Mol Hum Reprod 2017 Jun 1;23(6):406-416. doi: 10.1093/molehr/gax018. PMID: 28369513Free PMC Article

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