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Gain of Chromosome 7p

MedGen UID:
273363
•Concept ID:
C1517418
•
Cell or Molecular Dysfunction

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGain of Chromosome 7p

Professional guidelines

PubMed

Colorectal cancer genomics: evidence for multiple genotypes which influence survival.
Rooney PH, Boonsong A, McKay JA, Marsh S, Stevenson DA, Murray GI, Curran S, Haites NE, Cassidy J, McLeod HL
Br J Cancer 2001 Nov 16;85(10):1492-8. doi: 10.1054/bjoc.2001.2095. PMID: 11720434Free PMC Article
Molecular cytogenetic analysis of prostatic adenocarcinomas from screening studies : early cancers may contain aggressive genetic features.
Alers JC, Krijtenburg PJ, Vis AN, Hoedemaeker RF, Wildhagen MF, Hop WC, van Der Kwast TT, Schröder FH, Tanke HJ, van Dekken H
Am J Pathol 2001 Feb;158(2):399-406. doi: 10.1016/s0002-9440(10)63983-1. PMID: 11159178Free PMC Article

Recent clinical studies

Etiology

Prognostication of uveal melanoma is simple and highly predictive using The Cancer Genome Atlas (TCGA) classification: A review.
Shields CL, Dalvin LA, Vichitvejpaisal P, Mazloumi M, Ganguly A, Shields JA
Indian J Ophthalmol 2019 Dec;67(12):1959-1963. doi: 10.4103/ijo.IJO_1589_19. PMID: 31755428Free PMC Article
Clear cell renal cell carcinoma: identifying the gain of chromosome 20 on multiphasic MDCT.
Young JR, Young JA, Margolis DJ, Sauk S, Pantuck AJ, Sayre J, Raman SS
Abdom Radiol (NY) 2016 Nov;41(11):2175-2181. doi: 10.1007/s00261-016-0813-9. PMID: 27315079
Increased frequency of 20q gain and copy-neutral loss of heterozygosity in mismatch repair proficient familial colorectal carcinomas.
Middeldorp A, van Eijk R, Oosting J, Forte GI, van Puijenbroek M, van Nieuwenhuizen M, Corver WE, Ruano D, Caldes T, Wijnen J, Morreau H, van Wezel T
Int J Cancer 2012 Feb 15;130(4):837-46. Epub 2011 Jul 15 doi: 10.1002/ijc.26093. PMID: 21445971
Presence of 1q gain and absence of 7p gain are new predictors of local or metastatic relapse in localized resectable neuroblastoma.
Pezzolo A, Rossi E, Gimelli S, Parodi F, Negri F, Conte M, Pistorio A, Sementa A, Pistoia V, Zuffardi O, Gambini C
Neuro Oncol 2009 Apr;11(2):192-200. Epub 2008 Oct 15 doi: 10.1215/15228517-2008-086. PMID: 18923191Free PMC Article
Chromosomal abnormalities subdivide neuroepithelial tumors into clinically relevant groups.
Hirose Y, Yoshida K
Keio J Med 2006 Jun;55(2):52-8. doi: 10.2302/kjm.55.52. PMID: 16823260

Diagnosis

Comparison of Clinical, Histopathological, and Genomic Features Between Malignant Peripheral Nerve Sheath Tumors and Cellular Schwannomas of the Eighth Cranial Nerve: A Case Series.
Zhao F, Zhang S, Du J, Chen Y, Wang B, Zhang J, He Q, Lin L, Zhang L, Yu Y, Liu P
World Neurosurg 2019 Feb;122:e487-e497. Epub 2018 Oct 23 doi: 10.1016/j.wneu.2018.10.087. PMID: 30366145
Prognostic relevance of genetic alterations in diffuse lower-grade gliomas.
Aoki K, Nakamura H, Suzuki H, Matsuo K, Kataoka K, Shimamura T, Motomura K, Ohka F, Shiina S, Yamamoto T, Nagata Y, Yoshizato T, Mizoguchi M, Abe T, Momii Y, Muragaki Y, Watanabe R, Ito I, Sanada M, Yajima H, Morita N, Takeuchi I, Miyano S, Wakabayashi T, Ogawa S, Natsume A
Neuro Oncol 2018 Jan 10;20(1):66-77. doi: 10.1093/neuonc/nox132. PMID: 29016839Free PMC Article
Genomic profiling of atypical meningiomas associates gain of 1q with poor clinical outcome.
Gabeau-Lacet D, Engler D, Gupta S, Scangas GA, Betensky RA, Barker FG 2nd, Loeffler JS, Louis DN, Mohapatra G
J Neuropathol Exp Neurol 2009 Oct;68(10):1155-65. doi: 10.1097/NEN.0b013e3181ba3952. PMID: 19918127Free PMC Article
Presence of 1q gain and absence of 7p gain are new predictors of local or metastatic relapse in localized resectable neuroblastoma.
Pezzolo A, Rossi E, Gimelli S, Parodi F, Negri F, Conte M, Pistorio A, Sementa A, Pistoia V, Zuffardi O, Gambini C
Neuro Oncol 2009 Apr;11(2):192-200. Epub 2008 Oct 15 doi: 10.1215/15228517-2008-086. PMID: 18923191Free PMC Article
Chromosomal abnormalities subdivide neuroepithelial tumors into clinically relevant groups.
Hirose Y, Yoshida K
Keio J Med 2006 Jun;55(2):52-8. doi: 10.2302/kjm.55.52. PMID: 16823260

Therapy

Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study.
Inaba H, Zhou Y, Abla O, Adachi S, Auvrignon A, Beverloo HB, de Bont E, Chang TT, Creutzig U, Dworzak M, Elitzur S, Fynn A, Forestier E, Hasle H, Liang DC, Lee V, Locatelli F, Masetti R, De Moerloose B, Reinhardt D, Rodriguez L, Van Roy N, Shen S, Taga T, Tomizawa D, Yeoh AE, Zimmermann M, Raimondi SC
Blood 2015 Sep 24;126(13):1575-84. Epub 2015 Jul 27 doi: 10.1182/blood-2015-02-629204. PMID: 26215111Free PMC Article
Genomic profiling of malignant pleural mesothelioma with array-based comparative genomic hybridization shows frequent non-random chromosomal alteration regions including JUN amplification on 1p32.
Taniguchi T, Karnan S, Fukui T, Yokoyama T, Tagawa H, Yokoi K, Ueda Y, Mitsudomi T, Horio Y, Hida T, Yatabe Y, Seto M, Sekido Y
Cancer Sci 2007 Mar;98(3):438-46. doi: 10.1111/j.1349-7006.2006.00386.x. PMID: 17270034
Frequent occurrence of uniparental disomy in colorectal cancer.
Andersen CL, Wiuf C, Kruhøffer M, Korsgaard M, Laurberg S, Ørntoft TF
Carcinogenesis 2007 Jan;28(1):38-48. Epub 2006 Jun 13 doi: 10.1093/carcin/bgl086. PMID: 16774939
Additional cytogenetic abnormalities in adults with Philadelphia chromosome-positive acute lymphoblastic leukaemia: a study of the Cancer and Leukaemia Group B.
Wetzler M, Dodge RK, Mrózek K, Stewart CC, Carroll AJ, Tantravahi R, Vardiman JW, Larson RA, Bloomfield CD
Br J Haematol 2004 Feb;124(3):275-88. doi: 10.1046/j.1365-2141.2003.04736.x. PMID: 14717774
Chromosomal aberrations of primary lung adenocarcinomas in nonsmokers.
Wong MP, Fung LF, Wang E, Chow WS, Chiu SW, Lam WK, Ho KK, Ma ES, Wan TS, Chung LP
Cancer 2003 Mar 1;97(5):1263-70. doi: 10.1002/cncr.11183. PMID: 12599234

Prognosis

Prognostication of uveal melanoma is simple and highly predictive using The Cancer Genome Atlas (TCGA) classification: A review.
Shields CL, Dalvin LA, Vichitvejpaisal P, Mazloumi M, Ganguly A, Shields JA
Indian J Ophthalmol 2019 Dec;67(12):1959-1963. doi: 10.4103/ijo.IJO_1589_19. PMID: 31755428Free PMC Article
Clear cell renal cell carcinoma: identifying the gain of chromosome 20 on multiphasic MDCT.
Young JR, Young JA, Margolis DJ, Sauk S, Pantuck AJ, Sayre J, Raman SS
Abdom Radiol (NY) 2016 Nov;41(11):2175-2181. doi: 10.1007/s00261-016-0813-9. PMID: 27315079
Characterization of amplification patterns and target genes on the short arm of chromosome 7 in early-stage lung adenocarcinoma.
Kang JU
Mol Med Rep 2013 Nov;8(5):1373-8. Epub 2013 Sep 17 doi: 10.3892/mmr.2013.1686. PMID: 24045431
Genomic profiling of atypical meningiomas associates gain of 1q with poor clinical outcome.
Gabeau-Lacet D, Engler D, Gupta S, Scangas GA, Betensky RA, Barker FG 2nd, Loeffler JS, Louis DN, Mohapatra G
J Neuropathol Exp Neurol 2009 Oct;68(10):1155-65. doi: 10.1097/NEN.0b013e3181ba3952. PMID: 19918127Free PMC Article
Presence of 1q gain and absence of 7p gain are new predictors of local or metastatic relapse in localized resectable neuroblastoma.
Pezzolo A, Rossi E, Gimelli S, Parodi F, Negri F, Conte M, Pistorio A, Sementa A, Pistoia V, Zuffardi O, Gambini C
Neuro Oncol 2009 Apr;11(2):192-200. Epub 2008 Oct 15 doi: 10.1215/15228517-2008-086. PMID: 18923191Free PMC Article

Clinical prediction guides

Prognostication of uveal melanoma is simple and highly predictive using The Cancer Genome Atlas (TCGA) classification: A review.
Shields CL, Dalvin LA, Vichitvejpaisal P, Mazloumi M, Ganguly A, Shields JA
Indian J Ophthalmol 2019 Dec;67(12):1959-1963. doi: 10.4103/ijo.IJO_1589_19. PMID: 31755428Free PMC Article
Characterization of amplification patterns and target genes on the short arm of chromosome 7 in early-stage lung adenocarcinoma.
Kang JU
Mol Med Rep 2013 Nov;8(5):1373-8. Epub 2013 Sep 17 doi: 10.3892/mmr.2013.1686. PMID: 24045431
Identification of frequent BRAF copy number gain and alterations of RAF genes in Chinese prostate cancer.
Ren G, Liu X, Mao X, Zhang Y, Stankiewicz E, Hylands L, Song R, Berney DM, Clark J, Cooper C, Lu YJ
Genes Chromosomes Cancer 2012 Nov;51(11):1014-23. Epub 2012 Jul 25 doi: 10.1002/gcc.21984. PMID: 22833462
Increased frequency of 20q gain and copy-neutral loss of heterozygosity in mismatch repair proficient familial colorectal carcinomas.
Middeldorp A, van Eijk R, Oosting J, Forte GI, van Puijenbroek M, van Nieuwenhuizen M, Corver WE, Ruano D, Caldes T, Wijnen J, Morreau H, van Wezel T
Int J Cancer 2012 Feb 15;130(4):837-46. Epub 2011 Jul 15 doi: 10.1002/ijc.26093. PMID: 21445971
Presence of 1q gain and absence of 7p gain are new predictors of local or metastatic relapse in localized resectable neuroblastoma.
Pezzolo A, Rossi E, Gimelli S, Parodi F, Negri F, Conte M, Pistorio A, Sementa A, Pistoia V, Zuffardi O, Gambini C
Neuro Oncol 2009 Apr;11(2):192-200. Epub 2008 Oct 15 doi: 10.1215/15228517-2008-086. PMID: 18923191Free PMC Article

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