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Gain of Chromosome 7q32

MedGen UID:
273366
•Concept ID:
C1517421
•
Cell or Molecular Dysfunction

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGain of Chromosome 7q32

Recent clinical studies

Etiology

Acquired genetic alterations in tumor cells dictate the development of high-risk neuroblastoma and clinical outcomes.
Khan FH, Pandian V, Ramraj S, Natarajan M, Aravindan S, Herman TS, Aravindan N
BMC Cancer 2015 Jul 10;15:514. doi: 10.1186/s12885-015-1463-y. PMID: 26159519Free PMC Article
Genomic analysis of marginal zone and lymphoplasmacytic lymphomas identified common and disease-specific abnormalities.
Braggio E, Dogan A, Keats JJ, Chng WJ, Huang G, Matthews JM, Maurer MJ, Law ME, Bosler DS, Barrett M, Lossos IS, Witzig TE, Fonseca R
Mod Pathol 2012 May;25(5):651-60. Epub 2012 Feb 3 doi: 10.1038/modpathol.2011.213. PMID: 22301699Free PMC Article
cDNA array-CGH profiling identifies genomic alterations specific to stage and MYCN-amplification in neuroblastoma.
Chen QR, Bilke S, Wei JS, Whiteford CC, Cenacchi N, Krasnoselsky AL, Greer BT, Son CG, Westermann F, Berthold F, Schwab M, Catchpoole D, Khan J
BMC Genomics 2004 Sep 20;5:70. doi: 10.1186/1471-2164-5-70. PMID: 15380028Free PMC Article

Diagnosis

Osteogenesis imperfecta, tricho-dento-osseous syndrome and intellectual disability: a familial case with 17q21.33-q22 (COL1A1 and DLX3) deletion and 7q32.3-q33 duplication resulting from a reciprocal interchromosomal insertion.
Harbuz R, Bilan F, Couet D, Charraud V, Kitzis A, Gilbert-Dussardier B
Am J Med Genet A 2013 Oct;161A(10):2504-11. Epub 2013 Aug 15 doi: 10.1002/ajmg.a.36122. PMID: 23949819
Cytogenetic analysis of de novo CD5-positive diffuse large B-cell lymphoma.
Kaneko H, Shimura K, Horiike S, Kuroda J, Matsumoto Y, Yokota S, Nishida K, Ohkawara Y, Taniwaki M
Asia Pac J Clin Oncol 2011 Dec;7(4):346-50. doi: 10.1111/j.1743-7563.2011.01432.x. PMID: 22151983
cDNA array-CGH profiling identifies genomic alterations specific to stage and MYCN-amplification in neuroblastoma.
Chen QR, Bilke S, Wei JS, Whiteford CC, Cenacchi N, Krasnoselsky AL, Greer BT, Son CG, Westermann F, Berthold F, Schwab M, Catchpoole D, Khan J
BMC Genomics 2004 Sep 20;5:70. doi: 10.1186/1471-2164-5-70. PMID: 15380028Free PMC Article

Therapy

Oncogenic miR-96-5p inhibits apoptosis by targeting the caspase-9 gene in hepatocellular carcinoma.
Iwai N, Yasui K, Tomie A, Gen Y, Terasaki K, Kitaichi T, Soda T, Yamada N, Dohi O, Seko Y, Umemura A, Nishikawa T, Yamaguchi K, Moriguchi M, Konishi H, Naito Y, Itoh Y
Int J Oncol 2018 Jul;53(1):237-245. Epub 2018 Apr 12 doi: 10.3892/ijo.2018.4369. PMID: 29658604
Acquired genetic alterations in tumor cells dictate the development of high-risk neuroblastoma and clinical outcomes.
Khan FH, Pandian V, Ramraj S, Natarajan M, Aravindan S, Herman TS, Aravindan N
BMC Cancer 2015 Jul 10;15:514. doi: 10.1186/s12885-015-1463-y. PMID: 26159519Free PMC Article
cDNA array-CGH profiling identifies genomic alterations specific to stage and MYCN-amplification in neuroblastoma.
Chen QR, Bilke S, Wei JS, Whiteford CC, Cenacchi N, Krasnoselsky AL, Greer BT, Son CG, Westermann F, Berthold F, Schwab M, Catchpoole D, Khan J
BMC Genomics 2004 Sep 20;5:70. doi: 10.1186/1471-2164-5-70. PMID: 15380028Free PMC Article

Prognosis

Acquired genetic alterations in tumor cells dictate the development of high-risk neuroblastoma and clinical outcomes.
Khan FH, Pandian V, Ramraj S, Natarajan M, Aravindan S, Herman TS, Aravindan N
BMC Cancer 2015 Jul 10;15:514. doi: 10.1186/s12885-015-1463-y. PMID: 26159519Free PMC Article
WHO grade-specific comparative genomic hybridization pattern of astrocytoma - a meta-analysis.
Holland H, Koschny T, Ahnert P, Meixensberger J, Koschny R
Pathol Res Pract 2010 Oct 15;206(10):663-8. Epub 2010 Jun 1 doi: 10.1016/j.prp.2010.04.002. PMID: 20570053
cDNA array-CGH profiling identifies genomic alterations specific to stage and MYCN-amplification in neuroblastoma.
Chen QR, Bilke S, Wei JS, Whiteford CC, Cenacchi N, Krasnoselsky AL, Greer BT, Son CG, Westermann F, Berthold F, Schwab M, Catchpoole D, Khan J
BMC Genomics 2004 Sep 20;5:70. doi: 10.1186/1471-2164-5-70. PMID: 15380028Free PMC Article
Comparative genomic hybridization of malignant fibrous histiocytoma reveals a novel prognostic marker.
Larramendy ML, Tarkkanen M, Blomqvist C, Virolainen M, Wiklund T, Asko-Seljavaara S, Elomaa I, Knuutila S
Am J Pathol 1997 Oct;151(4):1153-61. PMID: 9327749Free PMC Article

Clinical prediction guides

Oncogenic miR-96-5p inhibits apoptosis by targeting the caspase-9 gene in hepatocellular carcinoma.
Iwai N, Yasui K, Tomie A, Gen Y, Terasaki K, Kitaichi T, Soda T, Yamada N, Dohi O, Seko Y, Umemura A, Nishikawa T, Yamaguchi K, Moriguchi M, Konishi H, Naito Y, Itoh Y
Int J Oncol 2018 Jul;53(1):237-245. Epub 2018 Apr 12 doi: 10.3892/ijo.2018.4369. PMID: 29658604
Genomic analysis of marginal zone and lymphoplasmacytic lymphomas identified common and disease-specific abnormalities.
Braggio E, Dogan A, Keats JJ, Chng WJ, Huang G, Matthews JM, Maurer MJ, Law ME, Bosler DS, Barrett M, Lossos IS, Witzig TE, Fonseca R
Mod Pathol 2012 May;25(5):651-60. Epub 2012 Feb 3 doi: 10.1038/modpathol.2011.213. PMID: 22301699Free PMC Article
Cytogenetic analysis of de novo CD5-positive diffuse large B-cell lymphoma.
Kaneko H, Shimura K, Horiike S, Kuroda J, Matsumoto Y, Yokota S, Nishida K, Ohkawara Y, Taniwaki M
Asia Pac J Clin Oncol 2011 Dec;7(4):346-50. doi: 10.1111/j.1743-7563.2011.01432.x. PMID: 22151983
Molecular characterization of the region 7q22.1 in splenic marginal zone lymphomas.
Robledo C, García JL, Benito R, Flores T, Mollejo M, Martínez-Climent JÁ, García E, Gutiérrez NC, Piris MA, Hernández JM
PLoS One 2011;6(9):e24939. Epub 2011 Sep 21 doi: 10.1371/journal.pone.0024939. PMID: 21957467Free PMC Article
Genomic imbalances of 7p and 17q in malignant peripheral nerve sheath tumors are clinically relevant.
Schmidt H, Würl P, Taubert H, Meye A, Bache M, Holzhausen HJ, Hinze R
Genes Chromosomes Cancer 1999 Jul;25(3):205-11. PMID: 10379866

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