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Cervical Mixed Epithelial and Mesenchymal Neoplasm

MedGen UID:
273909
Concept ID:
C1516420
Neoplastic Process

Definition

A benign or malignant neoplasm that arises from the cervix and is characterized by the presence of epithelial and mesenchymal elements. This category includes adenofibroma, adenomyoma, adenosarcoma, and carcinosarcoma. [from NCI]

Recent clinical studies

Etiology

Ranjbar M, Moradzadeh Khiavi M, Ghazi M, Derakhshan S
Asian Pac J Cancer Prev 2023 Aug 1;24(8):2845-2853. doi: 10.31557/APJCP.2023.24.8.2845. PMID: 37642073Free PMC Article
Kokubun K, Yamamoto K, Nakajima K, Akashi Y, Chujo T, Takano M, Katakura A, Matsuzaka K
Head Neck Pathol 2022 Jun;16(2):494-502. Epub 2021 Oct 30 doi: 10.1007/s12105-021-01390-w. PMID: 34716904Free PMC Article
Mühlenbrock MV, Navarrete-Rey P, Kovoor E, Guzman-Rojas R, Troncoso F, Miranda-Mendoza I
J Gynecol Obstet Hum Reprod 2021 Sep;50(7):101992. Epub 2020 Nov 17 doi: 10.1016/j.jogoh.2020.101992. PMID: 33217603
Coura BP, Bernardes VF, de Sousa SF, Diniz MG, Moreira RG, de Andrade BAB, Romañach MJ, Pontes HAR, Gomez RS, Odell EW, Gomes CC
J Mol Diagn 2020 Dec;22(12):1393-1399. Epub 2020 Sep 20 doi: 10.1016/j.jmoldx.2020.08.005. PMID: 32966885
Lopez-Chardi L, González-Bosquet E, Rovira Zurriaga C, Laïlla Vicens JM
Eur J Gynaecol Oncol 2013;34(4):336-8. PMID: 24020142

Diagnosis

Ranjbar M, Moradzadeh Khiavi M, Ghazi M, Derakhshan S
Asian Pac J Cancer Prev 2023 Aug 1;24(8):2845-2853. doi: 10.31557/APJCP.2023.24.8.2845. PMID: 37642073Free PMC Article
Kokubun K, Yamamoto K, Nakajima K, Akashi Y, Chujo T, Takano M, Katakura A, Matsuzaka K
Head Neck Pathol 2022 Jun;16(2):494-502. Epub 2021 Oct 30 doi: 10.1007/s12105-021-01390-w. PMID: 34716904Free PMC Article
Compton ML, Lewis JS Jr, Faquin WC, Cipriani NA, Shi Q, Ely KA
Head Neck Pathol 2022 Mar;16(1):229-235. Epub 2021 Jun 9 doi: 10.1007/s12105-021-01343-3. PMID: 34106411Free PMC Article
Park E, Kim YT, Kim S, Nam EJ, Cho NH
Mod Pathol 2021 Sep;34(9):1738-1749. Epub 2021 Jun 8 doi: 10.1038/s41379-021-00829-3. PMID: 34103667
Ding RB, Chen P, Rajendran BK, Lyu X, Wang H, Bao J, Zeng J, Hao W, Sun H, Wong AH, Valecha MV, Yang EJ, Su SM, Choi TK, Liu S, Chan KI, Yang LL, Wu J, Miao K, Chen Q, Shim JS, Xu X, Deng CX
Nat Commun 2021 May 24;12(1):3046. doi: 10.1038/s41467-021-23379-3. PMID: 34031426Free PMC Article

Therapy

Guo SS, Liu R, Wen YF, Liu LT, Yuan L, Li YX, Li Y, Hao WW, Peng JY, Chen DN, Tang QN, Sun XS, Guo L, Mo HY, Qian CN, Zeng MS, Bei JX, Sun SY, Chen QY, Tang LQ, Mai HQ
Cancer Lett 2020 Jan 1;468:27-40. Epub 2019 Oct 8 doi: 10.1016/j.canlet.2019.10.008. PMID: 31604115
Patnayak R, Rukmangadha N, Architha P, Reddy GS, Lakshmi AY, Kannan T, Jena A
Indian J Pathol Microbiol 2018 Jul-Sep;61(3):440-442. doi: 10.4103/IJPM.IJPM_1_18. PMID: 30004077
Johns ME, Mills SE, Thompson KK
Arch Otolaryngol 1983 Nov;109(11):709-14. doi: 10.1001/archotol.1983.00800250003001. PMID: 6314953

Prognosis

Nakai G, Matsutani H, Yamada T, Ohmichi M, Yamamoto K, Osuga K
BMC Womens Health 2021 Dec 16;21(1):416. doi: 10.1186/s12905-021-01567-z. PMID: 34915866Free PMC Article
Mühlenbrock MV, Navarrete-Rey P, Kovoor E, Guzman-Rojas R, Troncoso F, Miranda-Mendoza I
J Gynecol Obstet Hum Reprod 2021 Sep;50(7):101992. Epub 2020 Nov 17 doi: 10.1016/j.jogoh.2020.101992. PMID: 33217603
Zhang C, Ren X, Zhang W, He L, Qi L, Chen R, Tu C, Li Z
Bioengineered 2020 Dec;11(1):1112-1123. doi: 10.1080/21655979.2020.1831361. PMID: 33124951Free PMC Article
Guo SS, Liu R, Wen YF, Liu LT, Yuan L, Li YX, Li Y, Hao WW, Peng JY, Chen DN, Tang QN, Sun XS, Guo L, Mo HY, Qian CN, Zeng MS, Bei JX, Sun SY, Chen QY, Tang LQ, Mai HQ
Cancer Lett 2020 Jan 1;468:27-40. Epub 2019 Oct 8 doi: 10.1016/j.canlet.2019.10.008. PMID: 31604115
Schliekelman MJ, Taguchi A, Zhu J, Dai X, Rodriguez J, Celiktas M, Zhang Q, Chin A, Wong CH, Wang H, McFerrin L, Selamat SA, Yang C, Kroh EM, Garg KS, Behrens C, Gazdar AF, Laird-Offringa IA, Tewari M, Wistuba II, Thiery JP, Hanash SM
Cancer Res 2015 May 1;75(9):1789-800. Epub 2015 Mar 5 doi: 10.1158/0008-5472.CAN-14-2535. PMID: 25744723Free PMC Article

Clinical prediction guides

Xiao J, Song Y, Gao R, You M, Deng C, Tan G, Li W
J Transl Med 2023 Oct 31;21(1):771. doi: 10.1186/s12967-023-04650-1. PMID: 37907991Free PMC Article
Mühlenbrock MV, Navarrete-Rey P, Kovoor E, Guzman-Rojas R, Troncoso F, Miranda-Mendoza I
J Gynecol Obstet Hum Reprod 2021 Sep;50(7):101992. Epub 2020 Nov 17 doi: 10.1016/j.jogoh.2020.101992. PMID: 33217603
Coura BP, Bernardes VF, de Sousa SF, Diniz MG, Moreira RG, de Andrade BAB, Romañach MJ, Pontes HAR, Gomez RS, Odell EW, Gomes CC
J Mol Diagn 2020 Dec;22(12):1393-1399. Epub 2020 Sep 20 doi: 10.1016/j.jmoldx.2020.08.005. PMID: 32966885
Passador-Santos F, Martelli SJ, Gomes P, Teixeira LN, Soares AB, Gomez RS, de Araújo VC
Head Neck Pathol 2020 Dec;14(4):1149-1153. Epub 2020 Feb 5 doi: 10.1007/s12105-020-01136-0. PMID: 32026295Free PMC Article
Schliekelman MJ, Taguchi A, Zhu J, Dai X, Rodriguez J, Celiktas M, Zhang Q, Chin A, Wong CH, Wang H, McFerrin L, Selamat SA, Yang C, Kroh EM, Garg KS, Behrens C, Gazdar AF, Laird-Offringa IA, Tewari M, Wistuba II, Thiery JP, Hanash SM
Cancer Res 2015 May 1;75(9):1789-800. Epub 2015 Mar 5 doi: 10.1158/0008-5472.CAN-14-2535. PMID: 25744723Free PMC Article

Recent systematic reviews

Severino-Lazo RJG, de Vasconcelos Carvalho M, Campello CP, Moraes SLD, do Egito Vasconcelos BC, Pellizzer EP
Head Neck Pathol 2023 Dec;17(4):1000-1010. Epub 2023 Dec 6 doi: 10.1007/s12105-023-01601-6. PMID: 38057461Free PMC Article

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