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Papule of skin

MedGen UID:
274238
•Concept ID:
C1519353
•
Finding
Synonyms: Papular eruption; Papular Lesion; Papular rash; Papule; Skin Papule
SNOMED CT: Papular rash (70831001); Papule of skin (445328000); Papular eruption (70831001); Papular eruption (271757001)

Definition

A small (less than 5-10 mm) elevation of skin that is non-suppurative. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPapule of skin

Professional guidelines

PubMed

Scabies: Epidemiology, Diagnosis, and Treatment.
Sunderkötter C, Wohlrab J, Hamm H
Dtsch Arztebl Int 2021 Oct 15;118(41):695-704. doi: 10.3238/arztebl.m2021.0296. PMID: 34615594Free PMC Article
Juvenile Dermatomyositis: Advances in Pathogenesis, Assessment, and Management.
Leung AKC, Lam JM, Alobaida S, Leong KF, Wong AHC
Curr Pediatr Rev 2021;17(4):273-287. doi: 10.2174/1573396317666210426105045. PMID: 33902423
Rosacea: New Concepts in Classification and Treatment.
van Zuuren EJ, Arents BWM, van der Linden MMD, Vermeulen S, Fedorowicz Z, Tan J
Am J Clin Dermatol 2021 Jul;22(4):457-465. Epub 2021 Mar 23 doi: 10.1007/s40257-021-00595-7. PMID: 33759078Free PMC Article

Recent clinical studies

Etiology

Dermatomyositis: a comprehensive review of clinical manifestations, serological features, and therapeutic approaches.
Didona D, Solimani F, Caposiena Caro RD, Sequeira Santos AM, Hinterseher J, Kussini J, Cunha T, Hertl M, Didona B
Ital J Dermatol Venerol 2023 Apr;158(2):84-98. doi: 10.23736/S2784-8671.23.07458-3. PMID: 37153943
Pediatric joint hypermobility: a diagnostic framework and narrative review.
Tofts LJ, Simmonds J, Schwartz SB, Richheimer RM, O'Connor C, Elias E, Engelbert R, Cleary K, Tinkle BT, Kline AD, Hakim AJ, van Rossum MAJ, Pacey V
Orphanet J Rare Dis 2023 May 4;18(1):104. doi: 10.1186/s13023-023-02717-2. PMID: 37143135Free PMC Article
Juvenile Dermatomyositis: Advances in Pathogenesis, Assessment, and Management.
Leung AKC, Lam JM, Alobaida S, Leong KF, Wong AHC
Curr Pediatr Rev 2021;17(4):273-287. doi: 10.2174/1573396317666210426105045. PMID: 33902423
Basal Cell and Cutaneous Squamous Cell Carcinomas: Diagnosis and Treatment.
Firnhaber JM
Am Fam Physician 2020 Sep 15;102(6):339-346. PMID: 32931212
Pseudoxanthoma elasticum.
Germain DP
Orphanet J Rare Dis 2017 May 10;12(1):85. doi: 10.1186/s13023-017-0639-8. PMID: 28486967Free PMC Article

Diagnosis

Granulomatous annular diseases.
Uzuncakmak TK, Durdu M, Karadag AS
Clin Dermatol 2023 May-Jun;41(3):355-367. Epub 2023 Jul 17 doi: 10.1016/j.clindermatol.2023.07.004. PMID: 37467899
Atrophic Papulosis.
Robert M, Hot A
Dermatology 2023;239(2):177-187. Epub 2022 Nov 9 doi: 10.1159/000526789. PMID: 36353773
Extragenital lichen sclerosus: A comprehensive review.
Arif T, Fatima R, Sami M
Australas J Dermatol 2022 Nov;63(4):452-462. Epub 2022 Aug 11 doi: 10.1111/ajd.13890. PMID: 35950883
New Practical Aspects of Sweet Syndrome.
Joshi TP, Friske SK, Hsiou DA, Duvic M
Am J Clin Dermatol 2022 May;23(3):301-318. Epub 2022 Feb 14 doi: 10.1007/s40257-022-00673-4. PMID: 35157247Free PMC Article
Polymorphous Light Eruption.
Guarrera M
Adv Exp Med Biol 2017;996:61-70. doi: 10.1007/978-3-319-56017-5_6. PMID: 29124691

Therapy

Targeting Inflammation in Acne: Current Treatments and Future Prospects.
Cruz S, Vecerek N, Elbuluk N
Am J Clin Dermatol 2023 Sep;24(5):681-694. Epub 2023 Jun 16 doi: 10.1007/s40257-023-00789-1. PMID: 37328614Free PMC Article
Dermatomyositis: a comprehensive review of clinical manifestations, serological features, and therapeutic approaches.
Didona D, Solimani F, Caposiena Caro RD, Sequeira Santos AM, Hinterseher J, Kussini J, Cunha T, Hertl M, Didona B
Ital J Dermatol Venerol 2023 Apr;158(2):84-98. doi: 10.23736/S2784-8671.23.07458-3. PMID: 37153943
New Practical Aspects of Sweet Syndrome.
Joshi TP, Friske SK, Hsiou DA, Duvic M
Am J Clin Dermatol 2022 May;23(3):301-318. Epub 2022 Feb 14 doi: 10.1007/s40257-022-00673-4. PMID: 35157247Free PMC Article
Juvenile Dermatomyositis: Advances in Pathogenesis, Assessment, and Management.
Leung AKC, Lam JM, Alobaida S, Leong KF, Wong AHC
Curr Pediatr Rev 2021;17(4):273-287. doi: 10.2174/1573396317666210426105045. PMID: 33902423
A Review on Pityriasis Rubra Pilaris.
Wang D, Chong VC, Chong WS, Oon HH
Am J Clin Dermatol 2018 Jun;19(3):377-390. doi: 10.1007/s40257-017-0338-1. PMID: 29302927

Prognosis

Atrophic Papulosis.
Robert M, Hot A
Dermatology 2023;239(2):177-187. Epub 2022 Nov 9 doi: 10.1159/000526789. PMID: 36353773
Scleromyxedema.
Hoffmann JHO, Enk AH
J Dtsch Dermatol Ges 2020 Dec;18(12):1449-1467. doi: 10.1111/ddg.14319. PMID: 33373143
A Review on Pityriasis Rubra Pilaris.
Wang D, Chong VC, Chong WS, Oon HH
Am J Clin Dermatol 2018 Jun;19(3):377-390. doi: 10.1007/s40257-017-0338-1. PMID: 29302927
Drug induced psoriasis.
Milavec-Puretić V, Mance M, Ceović R, Lipozenčić J
Acta Dermatovenerol Croat 2011;19(1):39-42. PMID: 21489366
Papular urticaria.
Stibich AS, Schwartz RA
Cutis 2001 Aug;68(2):89-91. PMID: 11534921

Clinical prediction guides

Dermatomyositis: a comprehensive review of clinical manifestations, serological features, and therapeutic approaches.
Didona D, Solimani F, Caposiena Caro RD, Sequeira Santos AM, Hinterseher J, Kussini J, Cunha T, Hertl M, Didona B
Ital J Dermatol Venerol 2023 Apr;158(2):84-98. doi: 10.23736/S2784-8671.23.07458-3. PMID: 37153943
Extragenital lichen sclerosus: A comprehensive review.
Arif T, Fatima R, Sami M
Australas J Dermatol 2022 Nov;63(4):452-462. Epub 2022 Aug 11 doi: 10.1111/ajd.13890. PMID: 35950883
New Practical Aspects of Sweet Syndrome.
Joshi TP, Friske SK, Hsiou DA, Duvic M
Am J Clin Dermatol 2022 May;23(3):301-318. Epub 2022 Feb 14 doi: 10.1007/s40257-022-00673-4. PMID: 35157247Free PMC Article
Spitz Nevus: Review and Update.
Brown A, Sawyer JD, Neumeister MW
Clin Plast Surg 2021 Oct;48(4):677-686. Epub 2021 Aug 18 doi: 10.1016/j.cps.2021.06.002. PMID: 34503728
Juvenile Dermatomyositis: Advances in Pathogenesis, Assessment, and Management.
Leung AKC, Lam JM, Alobaida S, Leong KF, Wong AHC
Curr Pediatr Rev 2021;17(4):273-287. doi: 10.2174/1573396317666210426105045. PMID: 33902423

Recent systematic reviews

Efficacy and safety of topical treatments for seborrheic keratoses: a systematic review.
Natarelli N, Krenitsky A, Hennessy K, Moore S, Grichnik J
J Dermatolog Treat 2023 Dec;34(1):2133532. Epub 2022 Nov 13 doi: 10.1080/09546634.2022.2133532. PMID: 36215682
Use of Janus kinase inhibitors in dermatomyositis: a systematic literature review.
Paik JJ, Lubin G, Gromatzky A, Mudd PN Jr, Ponda MP, Christopher-Stine L
Clin Exp Rheumatol 2023 Mar;41(2):348-358. Epub 2022 Jun 28 doi: 10.55563/clinexprheumatol/hxin6o. PMID: 35766013Free PMC Article
Peristomal Skin Complications in Ileostomy and Colostomy Patients: What We Need to Know from a Public Health Perspective.
D'Ambrosio F, Pappalardo C, Scardigno A, Maida A, Ricciardi R, Calabrò GE
Int J Environ Res Public Health 2022 Dec 21;20(1) doi: 10.3390/ijerph20010079. PMID: 36612395Free PMC Article
Pathophysiology, clinical findings, and management of Fox-Fordyce disease: A systematic review.
Salloum A, Bouferraa Y, Bazzi N, Bou Zerdan M, Abi Chebl J, Chu T, Bachour J, Benedetto A
J Cosmet Dermatol 2022 Feb;21(2):482-500. Epub 2021 Apr 18 doi: 10.1111/jocd.14135. PMID: 33817950
Immunoglobulin-G4-related skin disease.
Katerji R, Smoller BR
Clin Dermatol 2021 Mar-Apr;39(2):283-290. Epub 2020 Oct 16 doi: 10.1016/j.clindermatol.2020.10.009. PMID: 34272023

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