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Leuteoma of Pregnancy

MedGen UID:
274668
•Concept ID:
C1517842
•
Disease or Syndrome

Definition

A non-neoplastic and self-limited condition that occurs during pregnancy. It is characterized by proliferation of luteinized stromal cells that replace the normal ovarian stromal cells. It is usually manifested with bilateral multinodular ovarian masses. Treatment is not required. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLeuteoma of Pregnancy

Professional guidelines

PubMed

Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline.
Bornstein SR, Allolio B, Arlt W, Barthel A, Don-Wauchope A, Hammer GD, Husebye ES, Merke DP, Murad MH, Stratakis CA, Torpy DJ
J Clin Endocrinol Metab 2016 Feb;101(2):364-89. Epub 2016 Jan 13 doi: 10.1210/jc.2015-1710. PMID: 26760044Free PMC Article
Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline.
Melmed S, Casanueva FF, Hoffman AR, Kleinberg DL, Montori VM, Schlechte JA, Wass JA; Endocrine Society
J Clin Endocrinol Metab 2011 Feb;96(2):273-88. doi: 10.1210/jc.2010-1692. PMID: 21296991
International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).
Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, Derksen RH, DE Groot PG, Koike T, Meroni PL, Reber G, Shoenfeld Y, Tincani A, Vlachoyiannopoulos PG, Krilis SA
J Thromb Haemost 2006 Feb;4(2):295-306. doi: 10.1111/j.1538-7836.2006.01753.x. PMID: 16420554

Recent clinical studies

Etiology

Monochorionic monoamniotic twin pregnancies.
Van Mieghem T, Abbasi N, Shinar S, Keunen J, Seaward G, Windrim R, Ryan G
Am J Obstet Gynecol MFM 2022 Mar;4(2S):100520. Epub 2021 Oct 30 doi: 10.1016/j.ajogmf.2021.100520. PMID: 34728404
Reduction of multiple pregnancy: Counselling and techniques.
Sebghati M, Khalil A
Best Pract Res Clin Obstet Gynaecol 2021 Jan;70:112-122. Epub 2020 Aug 6 doi: 10.1016/j.bpobgyn.2020.06.013. PMID: 32859535
Controversies in the management of twin pregnancy.
Khalil A, Liu B
Ultrasound Obstet Gynecol 2021 Jun;57(6):888-902. Epub 2021 May 21 doi: 10.1002/uog.22181. PMID: 32799348
Pregnancy of unknown location: Evaluation and management.
Carusi D
Semin Perinatol 2019 Mar;43(2):95-100. Epub 2018 Dec 20 doi: 10.1053/j.semperi.2018.12.006. PMID: 30606496
Time of implantation of the conceptus and loss of pregnancy.
Wilcox AJ, Baird DD, Weinberg CR
N Engl J Med 1999 Jun 10;340(23):1796-9. doi: 10.1056/NEJM199906103402304. PMID: 10362823

Diagnosis

Screening and diagnosis of chromosomal abnormalities in twin pregnancy.
D'Antonio F, Khalil A
Best Pract Res Clin Obstet Gynaecol 2022 Nov;84:229-239. Epub 2022 Oct 18 doi: 10.1016/j.bpobgyn.2022.10.001. PMID: 36335006
The vanishing twin: Diagnosis and implications.
Batsry L, Yinon Y
Best Pract Res Clin Obstet Gynaecol 2022 Nov;84:66-75. Epub 2022 Mar 30 doi: 10.1016/j.bpobgyn.2022.03.009. PMID: 35450773
Monochorionic monoamniotic twin pregnancies.
Van Mieghem T, Abbasi N, Shinar S, Keunen J, Seaward G, Windrim R, Ryan G
Am J Obstet Gynecol MFM 2022 Mar;4(2S):100520. Epub 2021 Oct 30 doi: 10.1016/j.ajogmf.2021.100520. PMID: 34728404
Controversies in the management of twin pregnancy.
Khalil A, Liu B
Ultrasound Obstet Gynecol 2021 Jun;57(6):888-902. Epub 2021 May 21 doi: 10.1002/uog.22181. PMID: 32799348
Pregnancy of unknown location: Evaluation and management.
Carusi D
Semin Perinatol 2019 Mar;43(2):95-100. Epub 2018 Dec 20 doi: 10.1053/j.semperi.2018.12.006. PMID: 30606496

Therapy

Induction of labour in low-risk pregnancies before 40 weeks of gestation: A systematic review and meta-analysis of randomized trials.
Dong S, Bapoo S, Shukla M, Abbasi N, Horn D, D'Souza R
Best Pract Res Clin Obstet Gynaecol 2022 Mar;79:107-125. Epub 2022 Jan 15 doi: 10.1016/j.bpobgyn.2021.12.007. PMID: 35086752
Cervical assessment by ultrasound for preventing preterm delivery.
Berghella V, Saccone G
Cochrane Database Syst Rev 2019 Sep 25;9(9):CD007235. doi: 10.1002/14651858.CD007235.pub4. PMID: 31553800Free PMC Article
Antispasmodics for labour.
Rohwer AC, Khondowe O, Young T
Cochrane Database Syst Rev 2012 Aug 15;(8):CD009243. doi: 10.1002/14651858.CD009243.pub2. PMID: 22895986
Chinese herbal medicines for threatened miscarriage.
Li L, Dou L, Leung PC, Wang CC
Cochrane Database Syst Rev 2012 May 16;(5):CD008510. doi: 10.1002/14651858.CD008510.pub2. PMID: 22592730
Recurrent spontaneous abortion.
McIntyre JA, Coulam CB, Faulk WP
Am J Reprod Immunol 1989 Nov-Dec;21(3-4):100-4. doi: 10.1111/j.1600-0897.1989.tb01011.x. PMID: 2534830

Prognosis

Incidence of myocardial infarction in pregnancy: a systematic review and meta-analysis of population-based studies.
Gibson P, Narous M, Firoz T, Chou D, Barreix M, Say L, James M; WHO Maternal Morbidity Working Group
Eur Heart J Qual Care Clin Outcomes 2017 Jul 1;3(3):198-207. doi: 10.1093/ehjqcco/qcw060. PMID: 28838086Free PMC Article
Predictors of Pregnancy Outcomes in Patients With Lupus: A Cohort Study.
Buyon JP, Kim MY, Guerra MM, Laskin CA, Petri M, Lockshin MD, Sammaritano L, Branch DW, Porter TF, Sawitzke A, Merrill JT, Stephenson MD, Cohn E, Garabet L, Salmon JE
Ann Intern Med 2015 Aug 4;163(3):153-63. doi: 10.7326/M14-2235. PMID: 26098843Free PMC Article
Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy.
Hutcheon JA, Lisonkova S, Joseph KS
Best Pract Res Clin Obstet Gynaecol 2011 Aug;25(4):391-403. Epub 2011 Feb 18 doi: 10.1016/j.bpobgyn.2011.01.006. PMID: 21333604
Planned caesarean section versus planned vaginal birth for breech presentation at term: a randomised multicentre trial. Term Breech Trial Collaborative Group.
Hannah ME, Hannah WJ, Hewson SA, Hodnett ED, Saigal S, Willan AR
Lancet 2000 Oct 21;356(9239):1375-83. doi: 10.1016/s0140-6736(00)02840-3. PMID: 11052579
Hypertension in pregnancy.
Svensson A
Clin Exp Hypertens 1993 Nov;15(6):1353-61. doi: 10.3109/10641969309037117. PMID: 8268895

Clinical prediction guides

Role of umbilicocerebral and cerebroplacental ratios in prediction of perinatal outcome in FGR pregnancies.
Coenen H, Braun J, Köster H, Möllers M, Schmitz R, Steinhard J, Oelmeier K
Arch Gynecol Obstet 2022 Jun;305(6):1383-1392. Epub 2021 Oct 2 doi: 10.1007/s00404-021-06268-4. PMID: 34599678Free PMC Article
The prediction of preterm delivery: What is new?
Suff N, Story L, Shennan A
Semin Fetal Neonatal Med 2019 Feb;24(1):27-32. Epub 2018 Sep 28 doi: 10.1016/j.siny.2018.09.006. PMID: 30337215
Diagnosing miscarriage.
Bottomley C, Bourne T
Best Pract Res Clin Obstet Gynaecol 2009 Aug;23(4):463-77. Epub 2009 Jun 6 doi: 10.1016/j.bpobgyn.2009.02.004. PMID: 19502113
Preinduction cervical assessment.
Edwards RK, Richards DS
Clin Obstet Gynecol 2000 Sep;43(3):440-6. doi: 10.1097/00003081-200009000-00004. PMID: 10949748
The nonstress test.
Keegan KA Jr
Clin Obstet Gynecol 1987 Dec;30(4):921-35. doi: 10.1097/00003081-198712000-00016. PMID: 3319323

Recent systematic reviews

A Systematic Review to Compare Adverse Pregnancy Outcomes in Women with Pregestational Diabetes and Gestational Diabetes.
Malaza N, Masete M, Adam S, Dias S, Nyawo T, Pheiffer C
Int J Environ Res Public Health 2022 Aug 31;19(17) doi: 10.3390/ijerph191710846. PMID: 36078559Free PMC Article
Management of anorexia nervosa in pregnancy: a systematic and state-of-the-art review.
Galbally M, Himmerich H, Senaratne S, Fitzgerald P, Frost J, Woods N, Dickinson JE
Lancet Psychiatry 2022 May;9(5):402-412. Epub 2022 Mar 24 doi: 10.1016/S2215-0366(22)00031-1. PMID: 35339207
Radiofrequency Ablation of Uterine Myomas and Pregnancy Outcomes: An Updated Review of the Literature.
Polin M, Hur HC
J Minim Invasive Gynecol 2022 Jun;29(6):709-715. Epub 2022 Feb 2 doi: 10.1016/j.jmig.2022.01.015. PMID: 35123041
Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis.
Chmielewska B, Barratt I, Townsend R, Kalafat E, van der Meulen J, Gurol-Urganci I, O'Brien P, Morris E, Draycott T, Thangaratinam S, Le Doare K, Ladhani S, von Dadelszen P, Magee L, Khalil A
Lancet Glob Health 2021 Jun;9(6):e759-e772. Epub 2021 Mar 31 doi: 10.1016/S2214-109X(21)00079-6. PMID: 33811827Free PMC Article
Epilepsy in pregnancy and reproductive outcomes: a systematic review and meta-analysis.
Viale L, Allotey J, Cheong-See F, Arroyo-Manzano D, Mccorry D, Bagary M, Mignini L, Khan KS, Zamora J, Thangaratinam S; EBM CONNECT Collaboration
Lancet 2015 Nov 7;386(10006):1845-52. Epub 2015 Aug 25 doi: 10.1016/S0140-6736(15)00045-8. PMID: 26318519

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