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Vaginal glandular neoplasm

MedGen UID:
275574
Concept ID:
C1519921
Neoplastic Process
Synonyms: vagina glandular cell neoplasm; Vaginal Glandular Neoplasm; vaginal glandular neoplasm; Vaginal Glandular Tumor; vaginal glandular tumor; vaginal glandular tumour
 
Monarch Initiative: MONDO:0001704

Definition

A benign or malignant neoplasm that arises from the vagina and is characterized by the presence of neoplastic glandular epithelial cells. Representative examples include adenoma, endometrioid adenocarcinoma, and clear cell adenocarcinoma. [from NCI]

Professional guidelines

PubMed

Kesic V, Carcopino X, Preti M, Vieira-Baptista P, Bevilacqua F, Bornstein J, Chargari C, Cruickshank M, Erzeneoglu E, Gallio N, Gultekin M, Heller D, Joura E, Kyrgiou M, Madić T, Planchamp F, Regauer S, Reich O, Esat Temiz B, Woelber L, Zodzika J, Stockdale C
Int J Gynecol Cancer 2023 Apr 3;33(4):446-461. doi: 10.1136/ijgc-2022-004213. PMID: 36958755Free PMC Article
Jhingran A
Int J Gynecol Cancer 2022 Mar;32(3):344-351. doi: 10.1136/ijgc-2021-002517. PMID: 35256422Free PMC Article
Rountis A, Pergialiotis V, Tsetsa P, Rodolakis A, Haidopoulos D
Int J Clin Pract 2020 Nov;74(11):e13598. Epub 2020 Aug 4 doi: 10.1111/ijcp.13598. PMID: 32602195

Recent clinical studies

Etiology

Leffelman A, Valaitis S
BMJ Case Rep 2022 Dec 22;15(12) doi: 10.1136/bcr-2022-250967. PMID: 36549754Free PMC Article
Rajaram S, Maheshwari A, Srivastava A
Best Pract Res Clin Obstet Gynaecol 2015 Aug;29(6):822-32. Epub 2015 Mar 4 doi: 10.1016/j.bpobgyn.2015.01.006. PMID: 25847318
McCluggage WG
Histopathology 2013 Jan;62(1):138-60. Epub 2012 Nov 8 doi: 10.1111/his.12012. PMID: 23134447
Shepherd JH
Best Pract Res Clin Obstet Gynaecol 2012 Jun;26(3):293-309. Epub 2012 Feb 19 doi: 10.1016/j.bpobgyn.2011.12.004. PMID: 22353492
Nout RA, Smit VT, Putter H, Jürgenliemk-Schulz IM, Jobsen JJ, Lutgens LC, van der Steen-Banasik EM, Mens JW, Slot A, Kroese MC, van Bunningen BN, Ansink AC, van Putten WL, Creutzberg CL; PORTEC Study Group
Lancet 2010 Mar 6;375(9717):816-23. doi: 10.1016/S0140-6736(09)62163-2. PMID: 20206777

Diagnosis

Elshennawy RA, Aird C, Boyle W, Yap J, Williams A, Ganesan R
Int J Gynecol Pathol 2023 Jul 1;42(4):327-337. Epub 2022 Oct 10 doi: 10.1097/PGP.0000000000000924. PMID: 36731045
Wei KX, Hoang LN
Surg Pathol Clin 2022 Jun;15(2):389-405. Epub 2022 May 20 doi: 10.1016/j.path.2022.02.011. PMID: 35715167
Jhingran A
Int J Gynecol Cancer 2022 Mar;32(3):344-351. doi: 10.1136/ijgc-2021-002517. PMID: 35256422Free PMC Article
Matthews N, Wong V, Brooks J, Kroumpouzos G
Clin Dermatol 2018 Mar-Apr;36(2):208-221. Epub 2017 Oct 3 doi: 10.1016/j.clindermatol.2017.10.012. PMID: 29566925
Nout RA, Smit VT, Putter H, Jürgenliemk-Schulz IM, Jobsen JJ, Lutgens LC, van der Steen-Banasik EM, Mens JW, Slot A, Kroese MC, van Bunningen BN, Ansink AC, van Putten WL, Creutzberg CL; PORTEC Study Group
Lancet 2010 Mar 6;375(9717):816-23. doi: 10.1016/S0140-6736(09)62163-2. PMID: 20206777

Therapy

van den Heerik ASVM, Horeweg N, Nout RA, Lutgens LCHW, van der Steen-Banasik EM, Westerveld GH, van den Berg HA, Slot A, Koppe FLA, Kommoss S, Mens JWM, Nowee ME, Bijmolt S, Cibula D, Stam TC, Jurgenliemk-Schulz IM, Snyers A, Hamann M, Zwanenburg AG, Coen VLMA, Vandecasteele K, Gillham C, Chargari C, Verhoeven-Adema KW, Putter H, van den Hout WB, Wortman BG, Nijman HW, Bosse T, Creutzberg CL
Int J Gynecol Cancer 2020 Dec;30(12):2002-2007. Epub 2020 Oct 12 doi: 10.1136/ijgc-2020-001929. PMID: 33046573Free PMC Article
Yang J, Delara R, Magrina J, Magtibay P, Langstraat C, Dinh T, Karlin N, Vora SA, Butler K
Gynecol Oncol 2020 Nov;159(2):456-463. Epub 2020 Sep 22 doi: 10.1016/j.ygyno.2020.08.036. PMID: 32972784
Wiebe E, Covens A, Thomas G
Int J Gynecol Cancer 2012 Nov;22(9):1611-6. doi: 10.1097/IGC.0b013e31826fd490. PMID: 23095777
Gurumurthy M, Cruickshank ME
J Low Genit Tract Dis 2012 Jul;16(3):306-12. doi: 10.1097/LGT.0b013e31823da7fb. PMID: 22460272
Nout RA, Smit VT, Putter H, Jürgenliemk-Schulz IM, Jobsen JJ, Lutgens LC, van der Steen-Banasik EM, Mens JW, Slot A, Kroese MC, van Bunningen BN, Ansink AC, van Putten WL, Creutzberg CL; PORTEC Study Group
Lancet 2010 Mar 6;375(9717):816-23. doi: 10.1016/S0140-6736(09)62163-2. PMID: 20206777

Prognosis

Arakawa A, Ichikawa H, Kubo T, Motoi N, Kumamoto T, Nakajima M, Yonemori K, Noguchi E, Sunami K, Shiraishi K, Kakishima H, Yoshida H, Hishiki T, Kawakubo N, Kuroda T, Kiyokawa T, Yamada K, Yanaihara N, Takahashi K, Okamoto A, Hirabayashi S, Hasegawa D, Manabe A, Ono K, Matsuoka M, Arai Y, Togashi Y, Shibata T, Nishikawa H, Aoki K, Yamamoto N, Kohno T, Ogawa C
N Engl J Med 2021 Jan 7;384(1):42-50. doi: 10.1056/NEJMoa2030391. PMID: 33406329
Matthews N, Wong V, Brooks J, Kroumpouzos G
Clin Dermatol 2018 Mar-Apr;36(2):208-221. Epub 2017 Oct 3 doi: 10.1016/j.clindermatol.2017.10.012. PMID: 29566925
Rajaram S, Maheshwari A, Srivastava A
Best Pract Res Clin Obstet Gynaecol 2015 Aug;29(6):822-32. Epub 2015 Mar 4 doi: 10.1016/j.bpobgyn.2015.01.006. PMID: 25847318
Wiebe E, Covens A, Thomas G
Int J Gynecol Cancer 2012 Nov;22(9):1611-6. doi: 10.1097/IGC.0b013e31826fd490. PMID: 23095777
Nout RA, Smit VT, Putter H, Jürgenliemk-Schulz IM, Jobsen JJ, Lutgens LC, van der Steen-Banasik EM, Mens JW, Slot A, Kroese MC, van Bunningen BN, Ansink AC, van Putten WL, Creutzberg CL; PORTEC Study Group
Lancet 2010 Mar 6;375(9717):816-23. doi: 10.1016/S0140-6736(09)62163-2. PMID: 20206777

Clinical prediction guides

Kelly ME, Heriot AG
Dis Colon Rectum 2023 Mar 1;66(3):355-357. Epub 2023 Jan 4 doi: 10.1097/DCR.0000000000002706. PMID: 36728599
Gomez Cherey JF, Payalef SN, Fleider L, Reyes AP, Maldonado VA, Losada MO, Chen X, Cardinal LH, Wang Y, Tatti SA, Perazzi BE
Int J Gynecol Cancer 2023 Apr 3;33(4):482-488. doi: 10.1136/ijgc-2022-003760. PMID: 36604120
Hakimjavadi H, George SH, Taub M, Dodds LV, Sanchez-Covarrubias AP, Huang M, Pearson JM, Slomovitz BM, Kobetz EN, Gharaibeh R, Sowamber R, Pinto A, Chamala S, Schlumbrecht MP
Cancer Res Commun 2022 Jun;2(6):447-455. Epub 2022 Jun 16 doi: 10.1158/2767-9764.CRC-22-0075. PMID: 35928983Free PMC Article
Pulkkinen J, Huhtala H, Krogerus LA, Hollmén S, Laurila M, Kholová I
Acta Cytol 2022;66(3):206-215. Epub 2022 Feb 28 doi: 10.1159/000522212. PMID: 35226896
Val-Bernal JF, Mayorga M
Pathol Res Pract 2016 Jun;212(6):568-72. Epub 2016 Feb 26 doi: 10.1016/j.prp.2016.02.023. PMID: 26970930

Recent systematic reviews

Rasmussen CL, Bertoli HK, Sand FL, Kjaer AK, Thomsen LT, Kjaer SK
Acta Obstet Gynecol Scand 2021 Dec;100(12):2144-2156. Epub 2021 Sep 21 doi: 10.1111/aogs.14260. PMID: 34546565
Unanyan A, Pivazyan L, Davydova J, Murvatova K, Khrapkova A, Movsisyan R, Ishchenko A, Ishchenko A
Photodiagnosis Photodyn Ther 2021 Dec;36:102530. Epub 2021 Sep 14 doi: 10.1016/j.pdpdt.2021.102530. PMID: 34534688
Inayama Y, Yamanishi Y, Nakatani E, Aratake J, Sasagasako N, Yamada K, Gou R, Kawamura A, Yamanishi M, Kosaka K
Gynecol Oncol 2021 Jan;160(1):140-147. Epub 2020 Oct 1 doi: 10.1016/j.ygyno.2020.09.031. PMID: 33010966
Pareja R, Rendón GJ, Sanz-Lomana CM, Monzón O, Ramirez PT
Gynecol Oncol 2013 Oct;131(1):77-82. Epub 2013 Jun 14 doi: 10.1016/j.ygyno.2013.06.010. PMID: 23769758
Marques JP, Costa LB, Pinto AP, Lima AF, Duarte ME, Barbosa AP, Medeiros PL
Rev Assoc Med Bras (1992) 2011 Mar-Apr;57(2):234-8. doi: 10.1590/s0104-42302011000200024. PMID: 21537713

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