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Loss of Chromosome 7

MedGen UID:
276488
Concept ID:
C1517989
Cell or Molecular Dysfunction
Synonyms: -7; del(7)

Definition

A cytogenic abnormality that refers to loss of all or part of chromosome 7. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLoss of Chromosome 7

Professional guidelines

PubMed

Velázquez Vega JE, Brat DJ, Ryken TC, Olson JJ
J Neurooncol 2020 Nov;150(2):143-164. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03616-3. PMID: 33215342
Lübbert M, Müller-Tidow C, Hofmann WK, Koeffler HP
J Cell Biochem 2008 Aug 15;104(6):2059-70. doi: 10.1002/jcb.21770. PMID: 18613031
Whang-Peng J, Young RC, Lee EC, Longo DL, Schechter GP, DeVita VT Jr
Blood 1988 Feb;71(2):403-14. PMID: 3337904

Recent clinical studies

Etiology

Diaz-Ortiz ME, Seo Y, Posavi M, Carceles Cordon M, Clark E, Jain N, Charan R, Gallagher MD, Unger TL, Amari N, Skrinak RT, Davila-Rivera R, Brody EM, Han N, Zack R, Van Deerlin VM, Tropea TF, Luk KC, Lee EB, Weintraub D, Chen-Plotkin AS
Science 2022 Aug 19;377(6608):eabk0637. doi: 10.1126/science.abk0637. PMID: 35981040Free PMC Article
Tesileanu CMS, Sanson M, Wick W, Brandes AA, Clement PM, Erridge SC, Vogelbaum MA, Nowak AK, Baurain JF, Mason WP, Wheeler H, Chinot OL, Gill S, Griffin M, Rogers L, Taal W, Rudà R, Weller M, McBain C, van Linde ME, Aldape K, Jenkins RB, Kros JM, Wesseling P, von Deimling A, Hoogstrate Y, de Heer I, Atmodimedjo PN, Dubbink HJ, Brouwer RWW, van IJcken WFJ, Cheung KJ, Golfinopoulos V, Baumert BG, Gorlia T, French PJ, van den Bent MJ
Clin Cancer Res 2022 Jun 13;28(12):2527-2535. doi: 10.1158/1078-0432.CCR-21-4283. PMID: 35275197Free PMC Article
Jotte MRM, McNerney ME
Curr Opin Hematol 2022 Mar 1;29(2):92-102. doi: 10.1097/MOH.0000000000000699. PMID: 35084368Free PMC Article
Komori T
Lab Invest 2022 Feb;102(2):126-133. Epub 2021 Sep 9 doi: 10.1038/s41374-021-00667-6. PMID: 34504304
Stichel D, Ebrahimi A, Reuss D, Schrimpf D, Ono T, Shirahata M, Reifenberger G, Weller M, Hänggi D, Wick W, Herold-Mende C, Westphal M, Brandner S, Pfister SM, Capper D, Sahm F, von Deimling A
Acta Neuropathol 2018 Nov;136(5):793-803. Epub 2018 Sep 5 doi: 10.1007/s00401-018-1905-0. PMID: 30187121

Diagnosis

López-Rivera JA, Leu C, Macnee M, Khoury J, Hoffmann L, Coras R, Kobow K, Bhattarai N, Pérez-Palma E, Hamer H, Brandner S, Rössler K, Bien CG, Kalbhenn T, Pieper T, Hartlieb T, Butler E, Genovese G, Becker K, Altmüller J, Niestroj LM, Ferguson L, Busch RM, Nürnberg P, Najm I, Blümcke I, Lal D
Brain 2023 Apr 19;146(4):1342-1356. doi: 10.1093/brain/awac376. PMID: 36226386Free PMC Article
Komori T
Lab Invest 2022 Feb;102(2):126-133. Epub 2021 Sep 9 doi: 10.1038/s41374-021-00667-6. PMID: 34504304
Śledzińska P, Bebyn MG, Furtak J, Kowalewski J, Lewandowska MA
Int J Mol Sci 2021 Sep 26;22(19) doi: 10.3390/ijms221910373. PMID: 34638714Free PMC Article
Galbraith K, Snuderl M
Surg Pathol Clin 2021 Sep;14(3):379-386. Epub 2021 Jul 8 doi: 10.1016/j.path.2021.05.003. PMID: 34373090
Stichel D, Ebrahimi A, Reuss D, Schrimpf D, Ono T, Shirahata M, Reifenberger G, Weller M, Hänggi D, Wick W, Herold-Mende C, Westphal M, Brandner S, Pfister SM, Capper D, Sahm F, von Deimling A
Acta Neuropathol 2018 Nov;136(5):793-803. Epub 2018 Sep 5 doi: 10.1007/s00401-018-1905-0. PMID: 30187121

Therapy

Tesileanu CMS, Sanson M, Wick W, Brandes AA, Clement PM, Erridge SC, Vogelbaum MA, Nowak AK, Baurain JF, Mason WP, Wheeler H, Chinot OL, Gill S, Griffin M, Rogers L, Taal W, Rudà R, Weller M, McBain C, van Linde ME, Aldape K, Jenkins RB, Kros JM, Wesseling P, von Deimling A, Hoogstrate Y, de Heer I, Atmodimedjo PN, Dubbink HJ, Brouwer RWW, van IJcken WFJ, Cheung KJ, Golfinopoulos V, Baumert BG, Gorlia T, French PJ, van den Bent MJ
Clin Cancer Res 2022 Jun 13;28(12):2527-2535. doi: 10.1158/1078-0432.CCR-21-4283. PMID: 35275197Free PMC Article
Abbas HA, Hao D, Tomczak K, Barrodia P, Im JS, Reville PK, Alaniz Z, Wang W, Wang R, Wang F, Al-Atrash G, Takahashi K, Ning J, Ding M, Beird HC, Mathews JT, Little L, Zhang J, Basu S, Konopleva M, Marques-Piubelli ML, Solis LM, Parra ER, Lu W, Tamegnon A, Garcia-Manero G, Green MR, Sharma P, Allison JP, Kornblau SM, Rai K, Wang L, Daver N, Futreal A
Nat Commun 2021 Oct 18;12(1):6071. doi: 10.1038/s41467-021-26282-z. PMID: 34663807Free PMC Article
Śledzińska P, Bebyn MG, Furtak J, Kowalewski J, Lewandowska MA
Int J Mol Sci 2021 Sep 26;22(19) doi: 10.3390/ijms221910373. PMID: 34638714Free PMC Article
Yoshida M, Tanase-Nakao K, Shima H, Shirai R, Yoshida K, Osumi T, Deguchi T, Mori M, Arakawa Y, Takagi M, Miyamura T, Sakaguchi K, Toyoda H, Ishida H, Sakata N, Imamura T, Kawahara Y, Morimoto A, Koike T, Yagasaki H, Ito S, Tomizawa D, Kiyokawa N, Narumi S, Kato M
Br J Haematol 2020 Dec;191(5):835-843. Epub 2020 Aug 7 doi: 10.1111/bjh.17006. PMID: 32770553
Honda H, Nagamachi A, Inaba T
Oncogene 2015 May 7;34(19):2413-25. Epub 2014 Jul 7 doi: 10.1038/onc.2014.196. PMID: 24998854

Prognosis

Tesileanu CMS, Sanson M, Wick W, Brandes AA, Clement PM, Erridge SC, Vogelbaum MA, Nowak AK, Baurain JF, Mason WP, Wheeler H, Chinot OL, Gill S, Griffin M, Rogers L, Taal W, Rudà R, Weller M, McBain C, van Linde ME, Aldape K, Jenkins RB, Kros JM, Wesseling P, von Deimling A, Hoogstrate Y, de Heer I, Atmodimedjo PN, Dubbink HJ, Brouwer RWW, van IJcken WFJ, Cheung KJ, Golfinopoulos V, Baumert BG, Gorlia T, French PJ, van den Bent MJ
Clin Cancer Res 2022 Jun 13;28(12):2527-2535. doi: 10.1158/1078-0432.CCR-21-4283. PMID: 35275197Free PMC Article
Komori T
Lab Invest 2022 Feb;102(2):126-133. Epub 2021 Sep 9 doi: 10.1038/s41374-021-00667-6. PMID: 34504304
Śledzińska P, Bebyn MG, Furtak J, Kowalewski J, Lewandowska MA
Int J Mol Sci 2021 Sep 26;22(19) doi: 10.3390/ijms221910373. PMID: 34638714Free PMC Article
Stichel D, Ebrahimi A, Reuss D, Schrimpf D, Ono T, Shirahata M, Reifenberger G, Weller M, Hänggi D, Wick W, Herold-Mende C, Westphal M, Brandner S, Pfister SM, Capper D, Sahm F, von Deimling A
Acta Neuropathol 2018 Nov;136(5):793-803. Epub 2018 Sep 5 doi: 10.1007/s00401-018-1905-0. PMID: 30187121
Pellagatti A, Boultwood J
Eur J Haematol 2015 Jul;95(1):3-15. Epub 2015 Feb 20 doi: 10.1111/ejh.12515. PMID: 25645650

Clinical prediction guides

López-Rivera JA, Leu C, Macnee M, Khoury J, Hoffmann L, Coras R, Kobow K, Bhattarai N, Pérez-Palma E, Hamer H, Brandner S, Rössler K, Bien CG, Kalbhenn T, Pieper T, Hartlieb T, Butler E, Genovese G, Becker K, Altmüller J, Niestroj LM, Ferguson L, Busch RM, Nürnberg P, Najm I, Blümcke I, Lal D
Brain 2023 Apr 19;146(4):1342-1356. doi: 10.1093/brain/awac376. PMID: 36226386Free PMC Article
Tesileanu CMS, Sanson M, Wick W, Brandes AA, Clement PM, Erridge SC, Vogelbaum MA, Nowak AK, Baurain JF, Mason WP, Wheeler H, Chinot OL, Gill S, Griffin M, Rogers L, Taal W, Rudà R, Weller M, McBain C, van Linde ME, Aldape K, Jenkins RB, Kros JM, Wesseling P, von Deimling A, Hoogstrate Y, de Heer I, Atmodimedjo PN, Dubbink HJ, Brouwer RWW, van IJcken WFJ, Cheung KJ, Golfinopoulos V, Baumert BG, Gorlia T, French PJ, van den Bent MJ
Clin Cancer Res 2022 Jun 13;28(12):2527-2535. doi: 10.1158/1078-0432.CCR-21-4283. PMID: 35275197Free PMC Article
Komori T
Lab Invest 2022 Feb;102(2):126-133. Epub 2021 Sep 9 doi: 10.1038/s41374-021-00667-6. PMID: 34504304
Śledzińska P, Bebyn MG, Furtak J, Kowalewski J, Lewandowska MA
Int J Mol Sci 2021 Sep 26;22(19) doi: 10.3390/ijms221910373. PMID: 34638714Free PMC Article
Stichel D, Ebrahimi A, Reuss D, Schrimpf D, Ono T, Shirahata M, Reifenberger G, Weller M, Hänggi D, Wick W, Herold-Mende C, Westphal M, Brandner S, Pfister SM, Capper D, Sahm F, von Deimling A
Acta Neuropathol 2018 Nov;136(5):793-803. Epub 2018 Sep 5 doi: 10.1007/s00401-018-1905-0. PMID: 30187121

Recent systematic reviews

Velázquez Vega JE, Brat DJ, Ryken TC, Olson JJ
J Neurooncol 2020 Nov;150(2):143-164. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03616-3. PMID: 33215342

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