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Neurotropism

MedGen UID:
276560
•Concept ID:
C1518304
•
Pathologic Function

Definition

Processes by which certain microorganisms and toxins are attracted to nervous tissue. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeurotropism

Professional guidelines

PubMed

Diagnostic Methods and Management Strategies of Herpes Simplex and Herpes Zoster Infections.
Mehrmal S, Mojica R, Guo AM, Missall TA
Clin Geriatr Med 2024 Feb;40(1):147-175. Epub 2023 Oct 8 doi: 10.1016/j.cger.2023.09.003. PMID: 38000858
A Comprehensive Review of Neurologic Manifestations of COVID-19 and Management of Pre-existing Neurologic Disorders in Children.
Kim Y, Walser SA, Asghar SJ, Jain R, Mainali G, Kumar A
J Child Neurol 2021 Mar;36(4):324-330. Epub 2020 Oct 28 doi: 10.1177/0883073820968995. PMID: 33112694Free PMC Article
Is psychosocial and cognitive dysfunction misattributed to the virus in hepatitis C infection? Select psychosocial contributors identified.
Lowry D, Burke T, Galvin Z, Ryan JD, Russell J, Murphy A, Hegarty J, Stewart S, Crowe J
J Viral Hepat 2016 Aug;23(8):584-95. Epub 2016 May 11 doi: 10.1111/jvh.12544. PMID: 27167497

Recent clinical studies

Etiology

Neuropathogenic human coronaviruses: A review.
Abdelaziz OS, Waffa Z
Rev Med Virol 2020 Sep;30(5):e2118. Epub 2020 Jul 20 doi: 10.1002/rmv.2118. PMID: 32687681Free PMC Article
Melanoma pathology reporting and staging.
Scolyer RA, Rawson RV, Gershenwald JE, Ferguson PM, Prieto VG
Mod Pathol 2020 Jan;33(Suppl 1):15-24. Epub 2019 Nov 22 doi: 10.1038/s41379-019-0402-x. PMID: 31758078
Infectious Myelopathies.
Grill MF
Continuum (Minneap Minn) 2018 Apr;24(2, Spinal Cord Disorders):441-473. doi: 10.1212/CON.0000000000000597. PMID: 29613895
Desmoplastic melanoma, neurotropism, and neurotrophin receptors--what we know and what we do not.
Frydenlund N, Mahalingam M
Adv Anat Pathol 2015 Jul;22(4):227-41. doi: 10.1097/PAP.0000000000000076. PMID: 26050260
Human herpesvirus 6.
Clark DA
Rev Med Virol 2000 May-Jun;10(3):155-73. doi: 10.1002/(sici)1099-1654(200005/06)10:3<155::aid-rmv277>3.0.co;2-6. PMID: 10815027

Diagnosis

Beyond Pattern Recognition: Radiology-Pathology-Clinical Correlation.
Wong KT, Tan CT, Lim T
Neuroimaging Clin N Am 2023 Feb;33(1):225-233. doi: 10.1016/j.nic.2022.07.018. PMID: 36404045
Pathogenesis of Relapsing Fever.
Lopez J, Hovius JW, Bergström S
Curr Issues Mol Biol 2021;42:519-550. Epub 2020 Dec 29 doi: 10.21775/cimb.042.519. PMID: 33372163Free PMC Article
Neurological and Neuropsychiatric Impacts of COVID-19 Pandemic.
Roy D, Ghosh R, Dubey S, Dubey MJ, Benito-León J, Kanti Ray B
Can J Neurol Sci 2021 Jan;48(1):9-24. Epub 2020 Aug 5 doi: 10.1017/cjn.2020.173. PMID: 32753076Free PMC Article
Melanoma pathology reporting and staging.
Scolyer RA, Rawson RV, Gershenwald JE, Ferguson PM, Prieto VG
Mod Pathol 2020 Jan;33(Suppl 1):15-24. Epub 2019 Nov 22 doi: 10.1038/s41379-019-0402-x. PMID: 31758078
Infectious Myelopathies.
Grill MF
Continuum (Minneap Minn) 2018 Apr;24(2, Spinal Cord Disorders):441-473. doi: 10.1212/CON.0000000000000597. PMID: 29613895

Therapy

COVID in obstetrics: labor analgesia and cesarean section.
Guasch E, Brogly N, Gilsanz F
Curr Opin Anaesthesiol 2021 Feb 1;34(1):62-68. doi: 10.1097/ACO.0000000000000949. PMID: 33315638
Effects of COVID-19 on the Nervous System.
Iadecola C, Anrather J, Kamel H
Cell 2020 Oct 1;183(1):16-27.e1. Epub 2020 Aug 19 doi: 10.1016/j.cell.2020.08.028. PMID: 32882182Free PMC Article
Vaccines against botulism.
Karalewitz AP, Barbieri JT
Curr Opin Microbiol 2012 Jun;15(3):317-24. Epub 2012 Jun 12 doi: 10.1016/j.mib.2012.05.009. PMID: 22694934
Reversal of resistance in microorganisms by help of non-antibiotics.
Kristiansen JE, Hendricks O, Delvin T, Butterworth TS, Aagaard L, Christensen JB, Flores VC, Keyzer H
J Antimicrob Chemother 2007 Jun;59(6):1271-9. Epub 2007 Apr 2 doi: 10.1093/jac/dkm071. PMID: 17403708
Cerebral phaeohyphomycosis.
Palaoglu S, Sav A, Basak T, Yalcinlar Y, Scheithauer BW
Neurosurgery 1993 Nov;33(5):894-7. doi: 10.1227/00006123-199311000-00018. PMID: 8264889

Prognosis

Olfactory and taste dysfunctions in COVID-19.
Rouadi PW, Idriss SA, Bousquet J
Curr Opin Allergy Clin Immunol 2021 Jun 1;21(3):229-244. doi: 10.1097/ACI.0000000000000735. PMID: 33560742
Psychiatric face of COVID-19.
Steardo L Jr, Steardo L, Verkhratsky A
Transl Psychiatry 2020 Jul 30;10(1):261. doi: 10.1038/s41398-020-00949-5. PMID: 32732883Free PMC Article
Melanoma pathology reporting and staging.
Scolyer RA, Rawson RV, Gershenwald JE, Ferguson PM, Prieto VG
Mod Pathol 2020 Jan;33(Suppl 1):15-24. Epub 2019 Nov 22 doi: 10.1038/s41379-019-0402-x. PMID: 31758078
Desmoplastic melanoma, neurotropism, and neurotrophin receptors--what we know and what we do not.
Frydenlund N, Mahalingam M
Adv Anat Pathol 2015 Jul;22(4):227-41. doi: 10.1097/PAP.0000000000000076. PMID: 26050260
Desmoplastic melanoma.
Batsakis JG, Raymond AK
Ann Otol Rhinol Laryngol 1994 Jan;103(1):77-9. doi: 10.1177/000348949410300115. PMID: 8291864

Clinical prediction guides

COVID-19 Induces Neuroinflammation and Suppresses Peroxisomes in the Brain.
Roczkowsky A, Limonta D, Fernandes JP, Branton WG, Clarke M, Hlavay B, Noyce RS, Joseph JT, Ogando NS, Das SK, Elaish M, Arbour N, Evans DH, Langdon K, Hobman TC, Power C
Ann Neurol 2023 Sep;94(3):531-546. Epub 2023 Jun 5 doi: 10.1002/ana.26679. PMID: 37190821
Emerging neurotropic features of SARS-CoV-2.
Zhan WR, Huang J, Zeng PM, Tian WY, Luo ZG
J Mol Cell Biol 2021 Dec 30;13(10):705-711. doi: 10.1093/jmcb/mjab044. PMID: 34289037Free PMC Article
Olfactory and taste dysfunctions in COVID-19.
Rouadi PW, Idriss SA, Bousquet J
Curr Opin Allergy Clin Immunol 2021 Jun 1;21(3):229-244. doi: 10.1097/ACI.0000000000000735. PMID: 33560742
SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids.
Pellegrini L, Albecka A, Mallery DL, Kellner MJ, Paul D, Carter AP, James LC, Lancaster MA
Cell Stem Cell 2020 Dec 3;27(6):951-961.e5. Epub 2020 Oct 13 doi: 10.1016/j.stem.2020.10.001. PMID: 33113348Free PMC Article
Melanoma pathology reporting and staging.
Scolyer RA, Rawson RV, Gershenwald JE, Ferguson PM, Prieto VG
Mod Pathol 2020 Jan;33(Suppl 1):15-24. Epub 2019 Nov 22 doi: 10.1038/s41379-019-0402-x. PMID: 31758078

Recent systematic reviews

SARS-Cov-2 infection and neuropathological findings: a report of 18 cases and review of the literature.
Lebrun L, Absil L, Remmelink M, De Mendonça R, D'Haene N, Gaspard N, Rusu S, Racu ML, Collin A, Allard J, Zindy E, Schiavo AA, De Clercq S, De Witte O, Decaestecker C, Lopes MB, Salmon I
Acta Neuropathol Commun 2023 May 10;11(1):78. doi: 10.1186/s40478-023-01566-1. PMID: 37165453Free PMC Article
Local Recurrence Rates After Excision of Desmoplastic Melanoma: A Systematic Review and Meta-Analysis.
Ran NA, Veerabagu S, Miller CJ, Elenitsas R, Chu EY, Krausz AE
Dermatol Surg 2023 Apr 1;49(4):330-337. Epub 2023 Mar 1 doi: 10.1097/DSS.0000000000003699. PMID: 36857167
Olfactory system measurements in COVID-19: a systematic review and meta-analysis.
Mohammadi S, Gouravani M, Salehi MA, Harandi H, Moosaie F, Dehghani Firouzabadi F, Yousem DM
Neuroradiology 2023 Jan;65(1):25-39. Epub 2022 Jul 18 doi: 10.1007/s00234-022-03014-8. PMID: 35843987Free PMC Article
SARS-CoV-2 and the brain: A review of the current knowledge on neuropathology in COVID-19.
Maiese A, Manetti AC, Bosetti C, Del Duca F, La Russa R, Frati P, Di Paolo M, Turillazzi E, Fineschi V
Brain Pathol 2021 Nov;31(6):e13013. Epub 2021 Aug 13 doi: 10.1111/bpa.13013. PMID: 34390282Free PMC Article
Does coronaviruses induce neurodegenerative diseases? A systematic review on the neurotropism and neuroinvasion of SARS-CoV-2.
ElBini Dhouib I
Drug Discov Ther 2021 Jan 23;14(6):262-272. Epub 2020 Dec 31 doi: 10.5582/ddt.2020.03106. PMID: 33390561

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