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Ovarian lymphoma

MedGen UID:
276669
•Concept ID:
C1518720
•
Neoplastic Process
Synonyms: lymphoma of ovary; Ovarian Lymphoma; ovarian lymphoma; ovary lymphoma; Primary Ovarian Lymphoma; primary ovarian lymphoma
 
Monarch Initiative: MONDO:0002227

Definition

A lymphoma that affects the ovary. Lymphomatous involvement of the ovary is rare and in approximately half of the cases both ovaries are affected. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian lymphoma

Professional guidelines

PubMed

Impact of Oncology Drug Shortages on Chemotherapy Treatment.
Alpert A, Jacobson M
Clin Pharmacol Ther 2019 Aug;106(2):415-421. Epub 2019 Apr 8 doi: 10.1002/cpt.1390. PMID: 30739322Free PMC Article
Weight loss as a predictor of cancer in primary care: a systematic review and meta-analysis.
Nicholson BD, Hamilton W, O'Sullivan J, Aveyard P, Hobbs FR
Br J Gen Pract 2018 May;68(670):e311-e322. Epub 2018 Apr 9 doi: 10.3399/bjgp18X695801. PMID: 29632004Free PMC Article
Conservative management in primary genital lymphomas: the role of chemotherapy.
Signorelli M, Maneo A, Cammarota S, Isimbaldi G, Garcia Parra R, Perego P, Maria Pogliani E, Mangioni C
Gynecol Oncol 2007 Feb;104(2):416-21. Epub 2006 Oct 16 doi: 10.1016/j.ygyno.2006.08.024. PMID: 17049970

Recent clinical studies

Etiology

Primary diffuse large B-cell lymphoma of the ovary is of a germinal centre B-cell-like phenotype.
Sun J, Zhang J, Ling Q, Luo Y, Wu S, Liang Z, Zhong D, Zeng X
Virchows Arch 2015 Jan;466(1):93-100. Epub 2014 Nov 18 doi: 10.1007/s00428-014-1682-7. PMID: 25403088
Diffuse large B-cell lymphoma occurring in an ovarian cystic teratoma: expanding the spectrum of large B-cell lymphoma associated with chronic inflammation.
Valli R, Froio E, Alvarez de Celis MI, Mandato VD, Piana S
Hum Pathol 2014 Dec;45(12):2507-11. Epub 2014 Sep 28 doi: 10.1016/j.humpath.2014.09.002. PMID: 25439346
Conservative management in primary genital lymphomas: the role of chemotherapy.
Signorelli M, Maneo A, Cammarota S, Isimbaldi G, Garcia Parra R, Perego P, Maria Pogliani E, Mangioni C
Gynecol Oncol 2007 Feb;104(2):416-21. Epub 2006 Oct 16 doi: 10.1016/j.ygyno.2006.08.024. PMID: 17049970
Differentiation of small adnexal masses based on morphologic characteristics of transvaginal sonographic imaging: a multicenter study.
Ferrazzi E, Lissoni AA, Dordoni D, Trio D, Redaelli L, Rusconi C, Sanpaolo P, Floriani I, Torri V, Zaglio S, Valcamonico A, Piol F, Berlanda N, Zanetta G
J Ultrasound Med 2005 Nov;24(11):1467-73; quiz 1475-6. doi: 10.7863/jum.2005.24.11.1467. PMID: 16239647
Lymphomas or leukemia presenting as ovarian tumors. An analysis of 42 cases.
Osborne BM, Robboy SJ
Cancer 1983 Nov 15;52(10):1933-43. doi: 10.1002/1097-0142(19831115)52:10<1933::aid-cncr2820521026>3.0.co;2-8. PMID: 6627208

Diagnosis

Non-Hodgkin's B-cell lymphoma of the ovary: A case report and review of the literature.
Sung YW, Lin YS, Chen YT, Yeh LS
Taiwan J Obstet Gynecol 2022 May;61(3):539-543. doi: 10.1016/j.tjog.2022.03.026. PMID: 35595455
Primary ovarian Burkitt's lymphoma: a rare oncological problem in gynaecology: a review of literature.
Stepniak A, Czuczwar P, Szkodziak P, Wozniakowska E, Wozniak S, Paszkowski T
Arch Gynecol Obstet 2017 Oct;296(4):653-660. Epub 2017 Aug 2 doi: 10.1007/s00404-017-4478-6. PMID: 28770352Free PMC Article
Ovarian lymphoma and hydronephrosis.
Volpi E, Bernardini L, Angeloni M, Gogna P, Intersimone D, Fedeli F
JSLS 2013 Oct-Dec;17(4):668-71. doi: 10.4293/108680813X13654754534918. PMID: 24398216Free PMC Article
Ovarian lymphoma.
Bambury I, Wharfe G, Fletcher H, Williams E, Jaggon J
J Obstet Gynaecol 2011 Oct;31(7):653-5. doi: 10.3109/01443615.2011.597893. PMID: 21973136
Primary ovarian malignant lymphoma presenting as ovarian carcinomatosis: a case report and literature review.
Kapetanakis V, Karlin NJ, McCullough AE, Magtibay PM
Eur J Gynaecol Oncol 2010;31(6):701-2. PMID: 21319522

Therapy

Non-Hodgkin's B-cell lymphoma of the ovary: A case report and review of the literature.
Sung YW, Lin YS, Chen YT, Yeh LS
Taiwan J Obstet Gynecol 2022 May;61(3):539-543. doi: 10.1016/j.tjog.2022.03.026. PMID: 35595455
Triple-hit high-grade B-cell lymphoma presenting with ovarian torsion.
Osataphan S, Augustynowicz A, Perrino C, Lam P
BMJ Case Rep 2021 May 31;14(5) doi: 10.1136/bcr-2021-242423. PMID: 34059546Free PMC Article
Primary ovarian Burkitt's lymphoma: a rare oncological problem in gynaecology: a review of literature.
Stepniak A, Czuczwar P, Szkodziak P, Wozniakowska E, Wozniak S, Paszkowski T
Arch Gynecol Obstet 2017 Oct;296(4):653-660. Epub 2017 Aug 2 doi: 10.1007/s00404-017-4478-6. PMID: 28770352Free PMC Article
Primary ovarian malignant lymphoma presenting as ovarian carcinomatosis: a case report and literature review.
Kapetanakis V, Karlin NJ, McCullough AE, Magtibay PM
Eur J Gynaecol Oncol 2010;31(6):701-2. PMID: 21319522
Ovarian follicular lymphoma: a case report and review of the literature.
Niitsu N, Nakamine H, Hayama M, Unno Y, Nakamura S, Horie R, Iwabuchi K, Nakamura N, Miura I, Higashihara M
Ann Hematol 2002 Nov;81(11):654-8. Epub 2002 Oct 12 doi: 10.1007/s00277-002-0545-5. PMID: 12454705

Prognosis

Primary ovarian Burkitt's lymphoma: a rare oncological problem in gynaecology: a review of literature.
Stepniak A, Czuczwar P, Szkodziak P, Wozniakowska E, Wozniak S, Paszkowski T
Arch Gynecol Obstet 2017 Oct;296(4):653-660. Epub 2017 Aug 2 doi: 10.1007/s00404-017-4478-6. PMID: 28770352Free PMC Article
Ovarian lymphoma.
Bambury I, Wharfe G, Fletcher H, Williams E, Jaggon J
J Obstet Gynaecol 2011 Oct;31(7):653-5. doi: 10.3109/01443615.2011.597893. PMID: 21973136
Primary ovarian malignant lymphoma presenting as ovarian carcinomatosis: a case report and literature review.
Kapetanakis V, Karlin NJ, McCullough AE, Magtibay PM
Eur J Gynaecol Oncol 2010;31(6):701-2. PMID: 21319522
Clinical features and prognostic relevance of ovarian involvement in non-Hodgkin's lymphoma: A Consortium for Improving Survival of Lymphoma (CISL) report.
Yun J, Kim SJ, Won JH, Choi CW, Eom HS, Kim JS, Kim MK, Kwak JY, Kim WS, Suh C
Leuk Res 2010 Sep;34(9):1175-9. Epub 2010 Mar 5 doi: 10.1016/j.leukres.2010.02.010. PMID: 20206997
Ovarian follicular lymphoma: a case report and review of the literature.
Niitsu N, Nakamine H, Hayama M, Unno Y, Nakamura S, Horie R, Iwabuchi K, Nakamura N, Miura I, Higashihara M
Ann Hematol 2002 Nov;81(11):654-8. Epub 2002 Oct 12 doi: 10.1007/s00277-002-0545-5. PMID: 12454705

Clinical prediction guides

Clinical features and prognostic relevance of ovarian involvement in non-Hodgkin's lymphoma: A Consortium for Improving Survival of Lymphoma (CISL) report.
Yun J, Kim SJ, Won JH, Choi CW, Eom HS, Kim JS, Kim MK, Kwak JY, Kim WS, Suh C
Leuk Res 2010 Sep;34(9):1175-9. Epub 2010 Mar 5 doi: 10.1016/j.leukres.2010.02.010. PMID: 20206997
Conservative management in primary genital lymphomas: the role of chemotherapy.
Signorelli M, Maneo A, Cammarota S, Isimbaldi G, Garcia Parra R, Perego P, Maria Pogliani E, Mangioni C
Gynecol Oncol 2007 Feb;104(2):416-21. Epub 2006 Oct 16 doi: 10.1016/j.ygyno.2006.08.024. PMID: 17049970
Ovarian Burkitt's lymphoma diagnosed by a combination of clinical features, morphology, immunophenotype, and molecular findings and successfully managed with surgery and chemotherapy.
Chishima F, Hayakawa S, Ohta Y, Sugita K, Yamazaki T, Sugitani M, Yamamoto T
Int J Gynecol Cancer 2006 Jan-Feb;16 Suppl 1:337-43. doi: 10.1111/j.1525-1438.2006.00207.x. PMID: 16515618
Differentiation of small adnexal masses based on morphologic characteristics of transvaginal sonographic imaging: a multicenter study.
Ferrazzi E, Lissoni AA, Dordoni D, Trio D, Redaelli L, Rusconi C, Sanpaolo P, Floriani I, Torri V, Zaglio S, Valcamonico A, Piol F, Berlanda N, Zanetta G
J Ultrasound Med 2005 Nov;24(11):1467-73; quiz 1475-6. doi: 10.7863/jum.2005.24.11.1467. PMID: 16239647
Differentiation potential of ovarian dysgerminoma: an immunohistochemical study of 15 cases.
Lifschitz-Mercer B, Walt H, Kushnir I, Jacob N, Diener PA, Moll R, Czernobilsky B
Hum Pathol 1995 Jan;26(1):62-6. doi: 10.1016/0046-8177(95)90115-9. PMID: 7821917

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