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Vulvar Melanocytic Neoplasm

MedGen UID:
276993
Concept ID:
C1520090
Neoplastic Process

Definition

A neoplasm that originates from melanocytes and arises from the vulva. This category includes congenital and acquired melanocytic nevus, blue nevus, dysplastic melanocytic nevus, atypical melanocytic nevus, genital type, and melanoma. [from NCI]

Professional guidelines

PubMed

Nobbenhuis MA, Lalondrelle S, Larkin J, Banerjee S
Curr Opin Oncol 2014 Sep;26(5):508-13. doi: 10.1097/CCO.0000000000000104. PMID: 25046205
Piura B
Lancet Oncol 2008 Oct;9(10):973-81. doi: 10.1016/S1470-2045(08)70254-7. PMID: 19071254

Recent clinical studies

Etiology

Rastegar S, Heller DS
J Low Genit Tract Dis 2021 Oct 1;25(4):303-311. doi: 10.1097/LGT.0000000000000624. PMID: 34542086
De Giorgi V, Gori A, Salvati L, Scarfì F, Maida P, Trane L, Silvestri F, Portelli F, Venturi F, Covarelli P, Massi D
JAMA Dermatol 2020 Nov 1;156(11):1185-1191. doi: 10.1001/jamadermatol.2020.2528. PMID: 32785609Free PMC Article
Goldemberg DC, Thuler LCS, de Melo AC
Acta Dermatovenerol Croat 2019 Mar;27(1):11-15. PMID: 31032785
Brenn T
Ann Diagn Pathol 2018 Dec;37:91-102. Epub 2018 Sep 27 doi: 10.1016/j.anndiagpath.2018.09.010. PMID: 30312883
Yang EJ, Kong CS, Longacre TA
Adv Anat Pathol 2017 May;24(3):136-150. doi: 10.1097/PAP.0000000000000149. PMID: 28398952

Diagnosis

Goldemberg DC, Thuler LCS, de Melo AC
Acta Dermatovenerol Croat 2019 Mar;27(1):11-15. PMID: 31032785
Brenn T
Ann Diagn Pathol 2018 Dec;37:91-102. Epub 2018 Sep 27 doi: 10.1016/j.anndiagpath.2018.09.010. PMID: 30312883
Allbritton JI
Obstet Gynecol Clin North Am 2017 Sep;44(3):339-352. doi: 10.1016/j.ogc.2017.04.002. PMID: 28778635
Yang EJ, Kong CS, Longacre TA
Adv Anat Pathol 2017 May;24(3):136-150. doi: 10.1097/PAP.0000000000000149. PMID: 28398952
Brenn T
Arch Pathol Lab Med 2011 Mar;135(3):317-20. doi: 10.5858/2009-0382-RA.1. PMID: 21366454

Therapy

De Giorgi V, Gori A, Salvati L, Scarfì F, Maida P, Trane L, Silvestri F, Portelli F, Venturi F, Covarelli P, Massi D
JAMA Dermatol 2020 Nov 1;156(11):1185-1191. doi: 10.1001/jamadermatol.2020.2528. PMID: 32785609Free PMC Article
Serra MC, Menicanti C, Pennacchioli E, Tosti G
An Bras Dermatol 2014 Sep-Oct;89(5):806-7. doi: 10.1590/abd1806-4841.20143058. PMID: 25184923Free PMC Article
Carrozzo AM, Cipriani C, Donati P, Muscardin L, Sedda AF
G Ital Dermatol Venereol 2014 Feb;149(1):115-21. PMID: 24566572
Bussen SS
Arch Gynecol Obstet 2009 Dec;280(6):1039-40. Epub 2009 Mar 28 doi: 10.1007/s00404-009-1049-5. PMID: 19330343
Seiji M, Takahashi M
Tohoku J Exp Med 1974 Oct;114(2):93-107. doi: 10.1620/tjem.114.93. PMID: 4612877

Prognosis

Wu Y, Li H, Tan L, Lai Y, Li Z
Hum Pathol 2023 Jan;131:87-97. Epub 2022 Nov 10 doi: 10.1016/j.humpath.2022.11.002. PMID: 36370822
De Giorgi V, Gori A, Salvati L, Scarfì F, Maida P, Trane L, Silvestri F, Portelli F, Venturi F, Covarelli P, Massi D
JAMA Dermatol 2020 Nov 1;156(11):1185-1191. doi: 10.1001/jamadermatol.2020.2528. PMID: 32785609Free PMC Article
Goldemberg DC, Thuler LCS, de Melo AC
Acta Dermatovenerol Croat 2019 Mar;27(1):11-15. PMID: 31032785
Murzaku EC, Penn LA, Hale CS, Pomeranz MK, Polsky D
J Am Acad Dermatol 2014 Dec;71(6):1241-9. Epub 2014 Sep 27 doi: 10.1016/j.jaad.2014.08.019. PMID: 25267379
Nobbenhuis MA, Lalondrelle S, Larkin J, Banerjee S
Curr Opin Oncol 2014 Sep;26(5):508-13. doi: 10.1097/CCO.0000000000000104. PMID: 25046205

Clinical prediction guides

Cohen Goldemberg D, de Melo AC, de Melo Pino LC, Thuler LCS
Sci Rep 2020 Jan 16;10(1):505. doi: 10.1038/s41598-019-57253-6. PMID: 31949210Free PMC Article
Heinzelmann-Schwarz VA, Nixdorf S, Valadan M, Diczbalis M, Olivier J, Otton G, Fedier A, Hacker NF, Scurry JP
Int J Mol Med 2014 Apr;33(4):784-94. Epub 2014 Feb 14 doi: 10.3892/ijmm.2014.1659. PMID: 24535703Free PMC Article
Cheung WL, Smoller BR
Dermatol Clin 2012 Oct;30(4):617-22, vi. Epub 2012 Aug 3 doi: 10.1016/j.det.2012.06.014. PMID: 23021049
Virgili A, Zampino MR, Marzola A, Corazza M
Dermatology 2010 Aug;221(1):55-62. Epub 2010 May 13 doi: 10.1159/000278259. PMID: 20484874
Ribé A
J Cutan Pathol 2008 Nov;35 Suppl 2:24-7. doi: 10.1111/j.1600-0560.2008.01150.x. PMID: 18976416

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