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Vulvar squamous neoplasm

MedGen UID:
276998
Concept ID:
C1520097
Neoplastic Process
Synonyms: mammalian vulva squamous cell neoplasm; Vulvar Squamous Neoplasm; vulvar squamous neoplasm; Vulvar Squamous Tumor; vulvar squamous tumor; vulvar squamous tumour
 
Monarch Initiative: MONDO:0002195

Definition

A benign, precancerous, or malignant neoplasm that arises from the squamous epithelium of the vulva. Representative examples include vestibular papilloma, intraepithelial neoplasia, and squamous cell carcinoma. [from NCI]

Professional guidelines

PubMed

Kesic V, Carcopino X, Preti M, Vieira-Baptista P, Bevilacqua F, Bornstein J, Chargari C, Cruickshank M, Erzeneoglu E, Gallio N, Gultekin M, Heller D, Joura E, Kyrgiou M, Madić T, Planchamp F, Regauer S, Reich O, Esat Temiz B, Woelber L, Zodzika J, Stockdale C
Int J Gynecol Cancer 2023 Apr 3;33(4):446-461. doi: 10.1136/ijgc-2022-004213. PMID: 36958755Free PMC Article
Merlo S
Radiol Oncol 2020 Sep 22;54(4):371-376. doi: 10.2478/raon-2020-0053. PMID: 32960779Free PMC Article
Lebreton M, Carton I, Brousse S, Lavoué V, Body G, Levêque J, Nyangoh-Timoh K
J Gynecol Obstet Hum Reprod 2020 Nov;49(9):101801. Epub 2020 May 14 doi: 10.1016/j.jogoh.2020.101801. PMID: 32417455

Recent clinical studies

Etiology

Parra-Herran C, Nucci MR, Singh N, Rakislova N, Howitt BE, Hoang L, Gilks CB, Bosse T, Watkins JC
Mod Pathol 2022 Oct;35(10):1317-1326. Epub 2022 Apr 18 doi: 10.1038/s41379-022-01079-7. PMID: 35437330
Olawaiye AB, Cuello MA, Rogers LJ
Int J Gynaecol Obstet 2021 Oct;155 Suppl 1(Suppl 1):7-18. doi: 10.1002/ijgo.13881. PMID: 34669204Free PMC Article
Lee A, Fischer G
Am J Clin Dermatol 2018 Oct;19(5):695-706. doi: 10.1007/s40257-018-0364-7. PMID: 29987650
Dellinger TH, Hakim AA, Lee SJ, Wakabayashi MT, Morgan RJ, Han ES
J Natl Compr Canc Netw 2017 Jan;15(1):121-128. doi: 10.6004/jnccn.2017.0009. PMID: 28040722
Van der Zee AG, Oonk MH, De Hullu JA, Ansink AC, Vergote I, Verheijen RH, Maggioni A, Gaarenstroom KN, Baldwin PJ, Van Dorst EB, Van der Velden J, Hermans RH, van der Putten H, Drouin P, Schneider A, Sluiter WJ
J Clin Oncol 2008 Feb 20;26(6):884-9. doi: 10.1200/JCO.2007.14.0566. PMID: 18281661

Diagnosis

Parra-Herran C, Nucci MR, Singh N, Rakislova N, Howitt BE, Hoang L, Gilks CB, Bosse T, Watkins JC
Mod Pathol 2022 Oct;35(10):1317-1326. Epub 2022 Apr 18 doi: 10.1038/s41379-022-01079-7. PMID: 35437330
Olawaiye AB, Cuello MA, Rogers LJ
Int J Gynaecol Obstet 2021 Oct;155 Suppl 1(Suppl 1):7-18. doi: 10.1002/ijgo.13881. PMID: 34669204Free PMC Article
Michalski BM, Pfeifer JD, Mutch D, Council ML
Dermatol Surg 2021 Feb 1;47(2):174-183. doi: 10.1097/DSS.0000000000002584. PMID: 32947298
Wohlmuth C, Wohlmuth-Wieser I
J Dtsch Dermatol Ges 2019 Dec;17(12):1257-1276. Epub 2019 Dec 12 doi: 10.1111/ddg.13995. PMID: 31829526Free PMC Article
Lee A, Fischer G
Am J Clin Dermatol 2018 Oct;19(5):695-706. doi: 10.1007/s40257-018-0364-7. PMID: 29987650

Therapy

Kesic V, Carcopino X, Preti M, Vieira-Baptista P, Bevilacqua F, Bornstein J, Chargari C, Cruickshank M, Erzeneoglu E, Gallio N, Gultekin M, Heller D, Joura E, Kyrgiou M, Madić T, Planchamp F, Regauer S, Reich O, Esat Temiz B, Woelber L, Zodzika J, Stockdale C
Int J Gynecol Cancer 2023 Apr 3;33(4):446-461. doi: 10.1136/ijgc-2022-004213. PMID: 36958755Free PMC Article
Li Z, Liu P, Wang Z, Zhang Z, Chen Z, Chu R, Li G, Han Q, Zhao Y, Li L, Miao J, Kong B, Song K
Lancet Oncol 2023 Apr;24(4):403-414. Epub 2023 Mar 15 doi: 10.1016/S1470-2045(23)00066-9. PMID: 36933562
Michalski BM, Pfeifer JD, Mutch D, Council ML
Dermatol Surg 2021 Feb 1;47(2):174-183. doi: 10.1097/DSS.0000000000002584. PMID: 32947298
Deli T, Orosz M, Jakab A
Pathol Oncol Res 2020 Jan;26(1):63-78. Epub 2019 Jan 8 doi: 10.1007/s12253-018-00569-x. PMID: 30617760Free PMC Article
Lee A, Fischer G
Am J Clin Dermatol 2018 Oct;19(5):695-706. doi: 10.1007/s40257-018-0364-7. PMID: 29987650

Prognosis

Merlo S
Radiol Oncol 2020 Sep 22;54(4):371-376. doi: 10.2478/raon-2020-0053. PMID: 32960779Free PMC Article
Lee A, Fischer G
Am J Clin Dermatol 2018 Oct;19(5):695-706. doi: 10.1007/s40257-018-0364-7. PMID: 29987650
Di Donato V, Casorelli A, Bardhi E, Vena F, Marchetti C, Muzii L, Benedetti Panici P
Crit Rev Oncol Hematol 2017 Sep;117:1-11. Epub 2017 Jun 13 doi: 10.1016/j.critrevonc.2017.06.005. PMID: 28807231
Dellinger TH, Hakim AA, Lee SJ, Wakabayashi MT, Morgan RJ, Han ES
J Natl Compr Canc Netw 2017 Jan;15(1):121-128. doi: 10.6004/jnccn.2017.0009. PMID: 28040722
Rajaram S, Gupta B
Rev Recent Clin Trials 2015;10(4):282-8. doi: 10.2174/1574887110666150923112723. PMID: 26411953

Clinical prediction guides

Roy SF, Wong J, Le Page C, Tran-Thanh D, Barkati M, Pina A, Trinh VQ, Rahimi K
Histopathology 2021 Dec;79(6):975-988. Epub 2021 Sep 20 doi: 10.1111/his.14451. PMID: 34265101
Carreras-Dieguez N, Guerrero J, Rodrigo-Calvo MT, Ribera-Cortada I, Trias I, Jares P, López Del Campo R, Saco A, Munmany M, Marimon L, Ferrando M, Vega N, Del Pino M, Torné A, Ordi J, Rakislova N
Int J Mol Sci 2021 Jun 30;22(13) doi: 10.3390/ijms22137069. PMID: 34209172Free PMC Article
Tessier-Cloutier B, Kortekaas KE, Thompson E, Pors J, Chen J, Ho J, Prentice LM, McConechy MK, Chow C, Proctor L, McAlpine JN, Huntsman DG, Gilks CB, Bosse T, Hoang LN
Mod Pathol 2020 Aug;33(8):1595-1605. Epub 2020 Mar 20 doi: 10.1038/s41379-020-0524-1. PMID: 32203095
Labernadie A, Kato T, Brugués A, Serra-Picamal X, Derzsi S, Arwert E, Weston A, González-Tarragó V, Elosegui-Artola A, Albertazzi L, Alcaraz J, Roca-Cusachs P, Sahai E, Trepat X
Nat Cell Biol 2017 Mar;19(3):224-237. Epub 2017 Feb 20 doi: 10.1038/ncb3478. PMID: 28218910Free PMC Article
Van der Zee AG, Oonk MH, De Hullu JA, Ansink AC, Vergote I, Verheijen RH, Maggioni A, Gaarenstroom KN, Baldwin PJ, Van Dorst EB, Van der Velden J, Hermans RH, van der Putten H, Drouin P, Schneider A, Sluiter WJ
J Clin Oncol 2008 Feb 20;26(6):884-9. doi: 10.1200/JCO.2007.14.0566. PMID: 18281661

Recent systematic reviews

Baandrup L, Sand FL, Aalborg GL, Nøttrup TJ, Fiehn AK, Kjaer SK
Histopathology 2024 Apr;84(5):742-752. Epub 2023 Dec 12 doi: 10.1111/his.15112. PMID: 38084642
Li Z, Liu P, Wang Z, Zhang Z, Chen Z, Chu R, Li G, Han Q, Zhao Y, Li L, Miao J, Kong B, Song K
Lancet Oncol 2023 Apr;24(4):403-414. Epub 2023 Mar 15 doi: 10.1016/S1470-2045(23)00066-9. PMID: 36933562
Santoro A, Angelico G, Travaglino A, Inzani F, Arciuolo D, Valente M, D'Alessandris N, Scaglione G, Piermattei A, Cianfrini F, Straccia P, Benvenuto R, Raffone A, Garganese G, Gallotta V, Zannoni GF
Eur J Surg Oncol 2022 Dec;48(12):2354-2359. Epub 2022 Jun 25 doi: 10.1016/j.ejso.2022.06.031. PMID: 35811178
Leis M, Singh A, Li C, Ahluwalia R, Fleming P, Lynde CW
J Obstet Gynaecol Can 2022 Feb;44(2):182-192. Epub 2021 Oct 19 doi: 10.1016/j.jogc.2021.09.023. PMID: 34678521
Makris GM, Poulakaki N, Papanota AM, Kotsifa E, Sergentanis TN, Psaltopoulou T
Dermatol Surg 2017 Jan;43(1):107-115. doi: 10.1097/DSS.0000000000000944. PMID: 27755170

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