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Localized Neoplasm

MedGen UID:
277420
•Concept ID:
C1334991
•
Neoplastic Process
Synonym: Non-Metastatic Neoplasm

Definition

A neoplasm that is confined to a specific site without evidence of spread to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocalized Neoplasm

Professional guidelines

PubMed

Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, Seligmann J, De Baere T, Osterlund P, Yoshino T, Martinelli E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Jan;34(1):10-32. Epub 2022 Oct 25 doi: 10.1016/j.annonc.2022.10.003. PMID: 36307056
Gastric cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Lordick F, Carneiro F, Cascinu S, Fleitas T, Haustermans K, Piessen G, Vogel A, Smyth EC; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2022 Oct;33(10):1005-1020. Epub 2022 Jul 29 doi: 10.1016/j.annonc.2022.07.004. PMID: 35914639
Expert consensus document: Clinical and molecular diagnosis, screening and management of Beckwith-Wiedemann syndrome: an international consensus statement.
Brioude F, Kalish JM, Mussa A, Foster AC, Bliek J, Ferrero GB, Boonen SE, Cole T, Baker R, Bertoletti M, Cocchi G, Coze C, De Pellegrin M, Hussain K, Ibrahim A, Kilby MD, Krajewska-Walasek M, Kratz CP, Ladusans EJ, Lapunzina P, Le Bouc Y, Maas SM, Macdonald F, Õunap K, Peruzzi L, Rossignol S, Russo S, Shipster C, Skórka A, Tatton-Brown K, Tenorio J, Tortora C, Grønskov K, Netchine I, Hennekam RC, Prawitt D, Tümer Z, Eggermann T, Mackay DJG, Riccio A, Maher ER
Nat Rev Endocrinol 2018 Apr;14(4):229-249. Epub 2018 Jan 29 doi: 10.1038/nrendo.2017.166. PMID: 29377879Free PMC Article

Recent clinical studies

Etiology

Redistribution of connexin43 expression in glomerular podocytes predicts poor renal prognosis in patients with type 2 diabetes and overt nephropathy.
Sawai K, Mukoyama M, Mori K, Yokoi H, Koshikawa M, Yoshioka T, Takeda R, Sugawara A, Kuwahara T, Saleem MA, Ogawa O, Nakao K
Nephrol Dial Transplant 2006 Sep;21(9):2472-7. Epub 2006 Jul 4 doi: 10.1093/ndt/gfl260. PMID: 16820374

Diagnosis

Solitary fibrous tumor of the larynx.
Thompson LD, Karamurzin Y, Wu ML, Kim JH
Head Neck Pathol 2008 Jun;2(2):67-74. Epub 2008 Mar 15 doi: 10.1007/s12105-008-0044-7. PMID: 20614325Free PMC Article
Redistribution of connexin43 expression in glomerular podocytes predicts poor renal prognosis in patients with type 2 diabetes and overt nephropathy.
Sawai K, Mukoyama M, Mori K, Yokoi H, Koshikawa M, Yoshioka T, Takeda R, Sugawara A, Kuwahara T, Saleem MA, Ogawa O, Nakao K
Nephrol Dial Transplant 2006 Sep;21(9):2472-7. Epub 2006 Jul 4 doi: 10.1093/ndt/gfl260. PMID: 16820374
Elevated endothelin-1 in tubular epithelium is associated with renal allograft rejection.
Chareandee C, Herman WH, Hricik DE, Simonson MS
Am J Kidney Dis 2000 Sep;36(3):541-9. doi: 10.1053/ajkd.2000.9795. PMID: 10977786
Primary large cell lymphoma of the mediastinum.
Aisenberg AC
Semin Oncol 1999 Jun;26(3):251-8. PMID: 10375082
Occult carcinoma of the bronchus.
Pearson FG, Thompson DW
Can Med Assoc J 1966 Apr 16;94(16):825-33. PMID: 5929532Free PMC Article

Therapy

Primary large cell lymphoma of the mediastinum.
Aisenberg AC
Semin Oncol 1999 Jun;26(3):251-8. PMID: 10375082

Prognosis

Solitary fibrous tumor of the larynx.
Thompson LD, Karamurzin Y, Wu ML, Kim JH
Head Neck Pathol 2008 Jun;2(2):67-74. Epub 2008 Mar 15 doi: 10.1007/s12105-008-0044-7. PMID: 20614325Free PMC Article
Redistribution of connexin43 expression in glomerular podocytes predicts poor renal prognosis in patients with type 2 diabetes and overt nephropathy.
Sawai K, Mukoyama M, Mori K, Yokoi H, Koshikawa M, Yoshioka T, Takeda R, Sugawara A, Kuwahara T, Saleem MA, Ogawa O, Nakao K
Nephrol Dial Transplant 2006 Sep;21(9):2472-7. Epub 2006 Jul 4 doi: 10.1093/ndt/gfl260. PMID: 16820374
Primary large cell lymphoma of the mediastinum.
Aisenberg AC
Semin Oncol 1999 Jun;26(3):251-8. PMID: 10375082
Lung structure and gas exchange in mild chronic obstructive pulmonary disease.
Barbera JA, Ramirez J, Roca J, Wagner PD, Sanchez-Lloret J, Rodriguez-Roisin R
Am Rev Respir Dis 1990 Apr;141(4 Pt 1):895-901. doi: 10.1164/ajrccm/141.4_Pt_1.895. PMID: 2327653
Occult carcinoma of the bronchus.
Pearson FG, Thompson DW
Can Med Assoc J 1966 Apr 16;94(16):825-33. PMID: 5929532Free PMC Article

Clinical prediction guides

Redistribution of connexin43 expression in glomerular podocytes predicts poor renal prognosis in patients with type 2 diabetes and overt nephropathy.
Sawai K, Mukoyama M, Mori K, Yokoi H, Koshikawa M, Yoshioka T, Takeda R, Sugawara A, Kuwahara T, Saleem MA, Ogawa O, Nakao K
Nephrol Dial Transplant 2006 Sep;21(9):2472-7. Epub 2006 Jul 4 doi: 10.1093/ndt/gfl260. PMID: 16820374
Elevated endothelin-1 in tubular epithelium is associated with renal allograft rejection.
Chareandee C, Herman WH, Hricik DE, Simonson MS
Am J Kidney Dis 2000 Sep;36(3):541-9. doi: 10.1053/ajkd.2000.9795. PMID: 10977786
Lung structure and gas exchange in mild chronic obstructive pulmonary disease.
Barbera JA, Ramirez J, Roca J, Wagner PD, Sanchez-Lloret J, Rodriguez-Roisin R
Am Rev Respir Dis 1990 Apr;141(4 Pt 1):895-901. doi: 10.1164/ajrccm/141.4_Pt_1.895. PMID: 2327653
Hyperplastic synoviocytes from rats with streptococcal cell wall-induced arthritis exhibit a transformed phenotype that is thymic-dependent and retinoid inhibitable.
Yocum DE, Lafyatis R, Remmers EF, Schumacher HR, Wilder RL
Am J Pathol 1988 Jul;132(1):38-48. PMID: 3260752Free PMC Article

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