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PRETEXT I Hepatoblastoma

MedGen UID:
277479
•Concept ID:
C1335255
•
Neoplastic Process
Synonyms: PRETEXT Stage 1 Hepatoblastoma; PRETEXT Stage I Hepatoblastoma

Definition

An internationally developed presurgical anatomic staging system using imaging techniques: Tumor involves only 1 quadrant; 3 adjoining liver quadrants are free of tumor. (from PDQ 2004) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPRETEXT I Hepatoblastoma

Professional guidelines

PubMed

Diagnosis, histopathologic correlation and management of hepatoblastoma: What the radiologist needs to know.
Baheti AD, Chapman T, Rudzinski E, Albert CM, Stanescu AL
Clin Imaging 2018 Nov-Dec;52:273-279. Epub 2018 Aug 18 doi: 10.1016/j.clinimag.2018.08.009. PMID: 30172849
2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT).
Towbin AJ, Meyers RL, Woodley H, Miyazaki O, Weldon CB, Morland B, Hiyama E, Czauderna P, Roebuck DJ, Tiao GM
Pediatr Radiol 2018 Apr;48(4):536-554. Epub 2018 Feb 9 doi: 10.1007/s00247-018-4078-z. PMID: 29427028
Management of hepatoblastoma: an update.
Kremer N, Walther AE, Tiao GM
Curr Opin Pediatr 2014 Jun;26(3):362-9. doi: 10.1097/MOP.0000000000000081. PMID: 24759227

Recent clinical studies

Etiology

Liver Tumors in Pediatric Patients.
Meyers R, Hiyama E, Czauderna P, Tiao GM
Surg Oncol Clin N Am 2021 Apr;30(2):253-274. doi: 10.1016/j.soc.2020.11.006. PMID: 33706899
Contemporary management of hepatoblastoma.
Hafberg E, Borinstein SC, Alexopoulos SP
Curr Opin Organ Transplant 2019 Apr;24(2):113-117. doi: 10.1097/MOT.0000000000000618. PMID: 30762666
2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT).
Towbin AJ, Meyers RL, Woodley H, Miyazaki O, Weldon CB, Morland B, Hiyama E, Czauderna P, Roebuck DJ, Tiao GM
Pediatr Radiol 2018 Apr;48(4):536-554. Epub 2018 Feb 9 doi: 10.1007/s00247-018-4078-z. PMID: 29427028
Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration.
Meyers RL, Maibach R, Hiyama E, Häberle B, Krailo M, Rangaswami A, Aronson DC, Malogolowkin MH, Perilongo G, von Schweinitz D, Ansari M, Lopez-Terrada D, Tanaka Y, Alaggio R, Leuschner I, Hishiki T, Schmid I, Watanabe K, Yoshimura K, Feng Y, Rinaldi E, Saraceno D, Derosa M, Czauderna P
Lancet Oncol 2017 Jan;18(1):122-131. Epub 2016 Nov 22 doi: 10.1016/S1470-2045(16)30598-8. PMID: 27884679Free PMC Article
Management of hepatoblastoma: an update.
Kremer N, Walther AE, Tiao GM
Curr Opin Pediatr 2014 Jun;26(3):362-9. doi: 10.1097/MOP.0000000000000081. PMID: 24759227

Diagnosis

Liver Tumors in Pediatric Patients.
Meyers R, Hiyama E, Czauderna P, Tiao GM
Surg Oncol Clin N Am 2021 Apr;30(2):253-274. doi: 10.1016/j.soc.2020.11.006. PMID: 33706899
Diagnosis, histopathologic correlation and management of hepatoblastoma: What the radiologist needs to know.
Baheti AD, Chapman T, Rudzinski E, Albert CM, Stanescu AL
Clin Imaging 2018 Nov-Dec;52:273-279. Epub 2018 Aug 18 doi: 10.1016/j.clinimag.2018.08.009. PMID: 30172849
Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration.
Meyers RL, Maibach R, Hiyama E, Häberle B, Krailo M, Rangaswami A, Aronson DC, Malogolowkin MH, Perilongo G, von Schweinitz D, Ansari M, Lopez-Terrada D, Tanaka Y, Alaggio R, Leuschner I, Hishiki T, Schmid I, Watanabe K, Yoshimura K, Feng Y, Rinaldi E, Saraceno D, Derosa M, Czauderna P
Lancet Oncol 2017 Jan;18(1):122-131. Epub 2016 Nov 22 doi: 10.1016/S1470-2045(16)30598-8. PMID: 27884679Free PMC Article
Malignant tumors of the liver in children.
Aronson DC, Meyers RL
Semin Pediatr Surg 2016 Oct;25(5):265-275. Epub 2016 Sep 4 doi: 10.1053/j.sempedsurg.2016.09.002. PMID: 27955729
Management of hepatoblastoma: an update.
Kremer N, Walther AE, Tiao GM
Curr Opin Pediatr 2014 Jun;26(3):362-9. doi: 10.1097/MOP.0000000000000081. PMID: 24759227

Therapy

2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT).
Towbin AJ, Meyers RL, Woodley H, Miyazaki O, Weldon CB, Morland B, Hiyama E, Czauderna P, Roebuck DJ, Tiao GM
Pediatr Radiol 2018 Apr;48(4):536-554. Epub 2018 Feb 9 doi: 10.1007/s00247-018-4078-z. PMID: 29427028
Surgical Resection for Hepatoblastoma-Updated Survival Outcomes.
Sunil BJ, Palaniappan R, Venkitaraman B, Ranganathan R
J Gastrointest Cancer 2018 Dec;49(4):493-496. doi: 10.1007/s12029-017-0005-z. PMID: 28963691
Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration.
Meyers RL, Maibach R, Hiyama E, Häberle B, Krailo M, Rangaswami A, Aronson DC, Malogolowkin MH, Perilongo G, von Schweinitz D, Ansari M, Lopez-Terrada D, Tanaka Y, Alaggio R, Leuschner I, Hishiki T, Schmid I, Watanabe K, Yoshimura K, Feng Y, Rinaldi E, Saraceno D, Derosa M, Czauderna P
Lancet Oncol 2017 Jan;18(1):122-131. Epub 2016 Nov 22 doi: 10.1016/S1470-2045(16)30598-8. PMID: 27884679Free PMC Article
Malignant tumors of the liver in children.
Aronson DC, Meyers RL
Semin Pediatr Surg 2016 Oct;25(5):265-275. Epub 2016 Sep 4 doi: 10.1053/j.sempedsurg.2016.09.002. PMID: 27955729
Surgical treatment of hepatoblastoma.
Meyers RL, Czauderna P, Otte JB
Pediatr Blood Cancer 2012 Nov;59(5):800-8. Epub 2012 Aug 8 doi: 10.1002/pbc.24220. PMID: 22887704

Prognosis

Tumor rupture in hepatoblastoma: A high risk factor?
Pondrom M, Pariente D, Mallon B, Taque S, Branchereau S, Chardot C, Laithier V, Tabone MD, Lejeune J, Faure-Conter C, Saumet L, Vérité C, Aerts I, Brugières L, Fresneau B
Pediatr Blood Cancer 2020 Sep;67(9):e28549. Epub 2020 Jul 3 doi: 10.1002/pbc.28549. PMID: 32618436
Diagnosis, histopathologic correlation and management of hepatoblastoma: What the radiologist needs to know.
Baheti AD, Chapman T, Rudzinski E, Albert CM, Stanescu AL
Clin Imaging 2018 Nov-Dec;52:273-279. Epub 2018 Aug 18 doi: 10.1016/j.clinimag.2018.08.009. PMID: 30172849
Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration.
Meyers RL, Maibach R, Hiyama E, Häberle B, Krailo M, Rangaswami A, Aronson DC, Malogolowkin MH, Perilongo G, von Schweinitz D, Ansari M, Lopez-Terrada D, Tanaka Y, Alaggio R, Leuschner I, Hishiki T, Schmid I, Watanabe K, Yoshimura K, Feng Y, Rinaldi E, Saraceno D, Derosa M, Czauderna P
Lancet Oncol 2017 Jan;18(1):122-131. Epub 2016 Nov 22 doi: 10.1016/S1470-2045(16)30598-8. PMID: 27884679Free PMC Article
Management of hepatoblastoma: an update.
Kremer N, Walther AE, Tiao GM
Curr Opin Pediatr 2014 Jun;26(3):362-9. doi: 10.1097/MOP.0000000000000081. PMID: 24759227
Hepatoblastoma state of the art: pre-treatment extent of disease, surgical resection guidelines and the role of liver transplantation.
Meyers RL, Tiao G, de Ville de Goyet J, Superina R, Aronson DC
Curr Opin Pediatr 2014 Feb;26(1):29-36. doi: 10.1097/MOP.0000000000000042. PMID: 24362406

Clinical prediction guides

Tumor rupture in hepatoblastoma: A high risk factor?
Pondrom M, Pariente D, Mallon B, Taque S, Branchereau S, Chardot C, Laithier V, Tabone MD, Lejeune J, Faure-Conter C, Saumet L, Vérité C, Aerts I, Brugières L, Fresneau B
Pediatr Blood Cancer 2020 Sep;67(9):e28549. Epub 2020 Jul 3 doi: 10.1002/pbc.28549. PMID: 32618436
Clinical risk stratification of children with SIOPEL high-risk hepatoblastoma in Taiwan.
Hsu WY, Chang HH, Lu MY, Yang YL, Jou ST, Chen HL, Ni YH, Hsu HY, Chang MH, Wu JF
Pediatr Neonatol 2020 Aug;61(4):393-398. Epub 2020 Mar 24 doi: 10.1016/j.pedneo.2020.03.012. PMID: 32291200
Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration.
Meyers RL, Maibach R, Hiyama E, Häberle B, Krailo M, Rangaswami A, Aronson DC, Malogolowkin MH, Perilongo G, von Schweinitz D, Ansari M, Lopez-Terrada D, Tanaka Y, Alaggio R, Leuschner I, Hishiki T, Schmid I, Watanabe K, Yoshimura K, Feng Y, Rinaldi E, Saraceno D, Derosa M, Czauderna P
Lancet Oncol 2017 Jan;18(1):122-131. Epub 2016 Nov 22 doi: 10.1016/S1470-2045(16)30598-8. PMID: 27884679Free PMC Article
PRETEXT II-III multifocal hepatoblastoma: significance of resection of satellite lesions irrespective of their disappearance after chemotherapy.
Qureshi SS, Bhagat M, Kembhavi S, Vora T, Ramadwar M, Talole S
Pediatr Surg Int 2015 Jun;31(6):573-9. Epub 2015 Apr 23 doi: 10.1007/s00383-015-3713-0. PMID: 25904441
Progress in the surgical treatment of malignant liver tumors in children.
Otte JB
Cancer Treat Rev 2010 Jun;36(4):360-71. Epub 2010 Mar 12 doi: 10.1016/j.ctrv.2010.02.013. PMID: 20227190

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