U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PRETEXT I Hepatoblastoma

MedGen UID:
277479
•Concept ID:
C1335255
•
Neoplastic Process
Synonyms: PRETEXT Stage 1 Hepatoblastoma; PRETEXT Stage I Hepatoblastoma

Definition

An internationally developed presurgical anatomic staging system using imaging techniques: Tumor involves only 1 quadrant; 3 adjoining liver quadrants are free of tumor. (from PDQ 2004) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPRETEXT I Hepatoblastoma

Professional guidelines

PubMed

Treatment outcomes and prognostic factors in children with hepatoblastoma using a risk-stratified approach.
Srinivasan S, Prasad M, Parambil BC, Shrimal A, Gollamudi VRM, Subramani V, Ramadwar M, Khanna N, Baheti AD, Gala K, Patil V, Laskar S, Qureshi S, Chinnaswamy G
Pediatr Blood Cancer 2023 Jul;70(7):e30302. Epub 2023 Apr 12 doi: 10.1002/pbc.30302. PMID: 37046413
Diagnosis, histopathologic correlation and management of hepatoblastoma: What the radiologist needs to know.
Baheti AD, Chapman T, Rudzinski E, Albert CM, Stanescu AL
Clin Imaging 2018 Nov-Dec;52:273-279. Epub 2018 Aug 18 doi: 10.1016/j.clinimag.2018.08.009. PMID: 30172849
2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT).
Towbin AJ, Meyers RL, Woodley H, Miyazaki O, Weldon CB, Morland B, Hiyama E, Czauderna P, Roebuck DJ, Tiao GM
Pediatr Radiol 2018 Apr;48(4):536-554. Epub 2018 Feb 9 doi: 10.1007/s00247-018-4078-z. PMID: 29427028

Recent clinical studies

Etiology

Liver Tumors in Pediatric Patients.
Meyers R, Hiyama E, Czauderna P, Tiao GM
Surg Oncol Clin N Am 2021 Apr;30(2):253-274. doi: 10.1016/j.soc.2020.11.006. PMID: 33706899
Contemporary management of hepatoblastoma.
Hafberg E, Borinstein SC, Alexopoulos SP
Curr Opin Organ Transplant 2019 Apr;24(2):113-117. doi: 10.1097/MOT.0000000000000618. PMID: 30762666
2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT).
Towbin AJ, Meyers RL, Woodley H, Miyazaki O, Weldon CB, Morland B, Hiyama E, Czauderna P, Roebuck DJ, Tiao GM
Pediatr Radiol 2018 Apr;48(4):536-554. Epub 2018 Feb 9 doi: 10.1007/s00247-018-4078-z. PMID: 29427028
Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration.
Meyers RL, Maibach R, Hiyama E, Häberle B, Krailo M, Rangaswami A, Aronson DC, Malogolowkin MH, Perilongo G, von Schweinitz D, Ansari M, Lopez-Terrada D, Tanaka Y, Alaggio R, Leuschner I, Hishiki T, Schmid I, Watanabe K, Yoshimura K, Feng Y, Rinaldi E, Saraceno D, Derosa M, Czauderna P
Lancet Oncol 2017 Jan;18(1):122-131. Epub 2016 Nov 22 doi: 10.1016/S1470-2045(16)30598-8. PMID: 27884679Free PMC Article
Surgical treatment of hepatoblastoma.
Meyers RL, Czauderna P, Otte JB
Pediatr Blood Cancer 2012 Nov;59(5):800-8. Epub 2012 Aug 8 doi: 10.1002/pbc.24220. PMID: 22887704

Diagnosis

An update on diagnosis and treatment of hepatoblastoma.
Cao Y, Wu S, Tang H
Biosci Trends 2024 Jan 30;17(6):445-457. Epub 2023 Dec 23 doi: 10.5582/bst.2023.01311. PMID: 38143081
Liver Tumors in Pediatric Patients.
Meyers R, Hiyama E, Czauderna P, Tiao GM
Surg Oncol Clin N Am 2021 Apr;30(2):253-274. doi: 10.1016/j.soc.2020.11.006. PMID: 33706899
Diagnosis, histopathologic correlation and management of hepatoblastoma: What the radiologist needs to know.
Baheti AD, Chapman T, Rudzinski E, Albert CM, Stanescu AL
Clin Imaging 2018 Nov-Dec;52:273-279. Epub 2018 Aug 18 doi: 10.1016/j.clinimag.2018.08.009. PMID: 30172849
Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration.
Meyers RL, Maibach R, Hiyama E, Häberle B, Krailo M, Rangaswami A, Aronson DC, Malogolowkin MH, Perilongo G, von Schweinitz D, Ansari M, Lopez-Terrada D, Tanaka Y, Alaggio R, Leuschner I, Hishiki T, Schmid I, Watanabe K, Yoshimura K, Feng Y, Rinaldi E, Saraceno D, Derosa M, Czauderna P
Lancet Oncol 2017 Jan;18(1):122-131. Epub 2016 Nov 22 doi: 10.1016/S1470-2045(16)30598-8. PMID: 27884679Free PMC Article
Malignant tumors of the liver in children.
Aronson DC, Meyers RL
Semin Pediatr Surg 2016 Oct;25(5):265-275. Epub 2016 Sep 4 doi: 10.1053/j.sempedsurg.2016.09.002. PMID: 27955729

Therapy

An update on diagnosis and treatment of hepatoblastoma.
Cao Y, Wu S, Tang H
Biosci Trends 2024 Jan 30;17(6):445-457. Epub 2023 Dec 23 doi: 10.5582/bst.2023.01311. PMID: 38143081
2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT).
Towbin AJ, Meyers RL, Woodley H, Miyazaki O, Weldon CB, Morland B, Hiyama E, Czauderna P, Roebuck DJ, Tiao GM
Pediatr Radiol 2018 Apr;48(4):536-554. Epub 2018 Feb 9 doi: 10.1007/s00247-018-4078-z. PMID: 29427028
Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration.
Meyers RL, Maibach R, Hiyama E, Häberle B, Krailo M, Rangaswami A, Aronson DC, Malogolowkin MH, Perilongo G, von Schweinitz D, Ansari M, Lopez-Terrada D, Tanaka Y, Alaggio R, Leuschner I, Hishiki T, Schmid I, Watanabe K, Yoshimura K, Feng Y, Rinaldi E, Saraceno D, Derosa M, Czauderna P
Lancet Oncol 2017 Jan;18(1):122-131. Epub 2016 Nov 22 doi: 10.1016/S1470-2045(16)30598-8. PMID: 27884679Free PMC Article
Malignant tumors of the liver in children.
Aronson DC, Meyers RL
Semin Pediatr Surg 2016 Oct;25(5):265-275. Epub 2016 Sep 4 doi: 10.1053/j.sempedsurg.2016.09.002. PMID: 27955729
Surgical treatment of hepatoblastoma.
Meyers RL, Czauderna P, Otte JB
Pediatr Blood Cancer 2012 Nov;59(5):800-8. Epub 2012 Aug 8 doi: 10.1002/pbc.24220. PMID: 22887704

Prognosis

Surgical Management and Outcomes of Patients with Multifocal Hepatoblastoma.
Whitlock RS, Portuondo JI, Espinoza AF, Ortega R, Galván NTN, Leung DH, Lopez-Terrada D, Masand P, Nguyen HN, Patel KA, Goss JA, Heczey AM, Vasudevan SA
J Pediatr Surg 2023 Sep;58(9):1715-1726. Epub 2023 May 8 doi: 10.1016/j.jpedsurg.2023.05.001. PMID: 37244849
Treatment outcomes and prognostic factors in children with hepatoblastoma using a risk-stratified approach.
Srinivasan S, Prasad M, Parambil BC, Shrimal A, Gollamudi VRM, Subramani V, Ramadwar M, Khanna N, Baheti AD, Gala K, Patil V, Laskar S, Qureshi S, Chinnaswamy G
Pediatr Blood Cancer 2023 Jul;70(7):e30302. Epub 2023 Apr 12 doi: 10.1002/pbc.30302. PMID: 37046413
Diagnosis, histopathologic correlation and management of hepatoblastoma: What the radiologist needs to know.
Baheti AD, Chapman T, Rudzinski E, Albert CM, Stanescu AL
Clin Imaging 2018 Nov-Dec;52:273-279. Epub 2018 Aug 18 doi: 10.1016/j.clinimag.2018.08.009. PMID: 30172849
Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration.
Meyers RL, Maibach R, Hiyama E, Häberle B, Krailo M, Rangaswami A, Aronson DC, Malogolowkin MH, Perilongo G, von Schweinitz D, Ansari M, Lopez-Terrada D, Tanaka Y, Alaggio R, Leuschner I, Hishiki T, Schmid I, Watanabe K, Yoshimura K, Feng Y, Rinaldi E, Saraceno D, Derosa M, Czauderna P
Lancet Oncol 2017 Jan;18(1):122-131. Epub 2016 Nov 22 doi: 10.1016/S1470-2045(16)30598-8. PMID: 27884679Free PMC Article
Management of hepatoblastoma: an update.
Kremer N, Walther AE, Tiao GM
Curr Opin Pediatr 2014 Jun;26(3):362-9. doi: 10.1097/MOP.0000000000000081. PMID: 24759227

Clinical prediction guides

Treatment outcomes and prognostic factors in children with hepatoblastoma using a risk-stratified approach.
Srinivasan S, Prasad M, Parambil BC, Shrimal A, Gollamudi VRM, Subramani V, Ramadwar M, Khanna N, Baheti AD, Gala K, Patil V, Laskar S, Qureshi S, Chinnaswamy G
Pediatr Blood Cancer 2023 Jul;70(7):e30302. Epub 2023 Apr 12 doi: 10.1002/pbc.30302. PMID: 37046413
Tumor rupture in hepatoblastoma: A high risk factor?
Pondrom M, Pariente D, Mallon B, Taque S, Branchereau S, Chardot C, Laithier V, Tabone MD, Lejeune J, Faure-Conter C, Saumet L, Vérité C, Aerts I, Brugières L, Fresneau B
Pediatr Blood Cancer 2020 Sep;67(9):e28549. Epub 2020 Jul 3 doi: 10.1002/pbc.28549. PMID: 32618436
Clinical risk stratification of children with SIOPEL high-risk hepatoblastoma in Taiwan.
Hsu WY, Chang HH, Lu MY, Yang YL, Jou ST, Chen HL, Ni YH, Hsu HY, Chang MH, Wu JF
Pediatr Neonatol 2020 Aug;61(4):393-398. Epub 2020 Mar 24 doi: 10.1016/j.pedneo.2020.03.012. PMID: 32291200
Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration.
Meyers RL, Maibach R, Hiyama E, Häberle B, Krailo M, Rangaswami A, Aronson DC, Malogolowkin MH, Perilongo G, von Schweinitz D, Ansari M, Lopez-Terrada D, Tanaka Y, Alaggio R, Leuschner I, Hishiki T, Schmid I, Watanabe K, Yoshimura K, Feng Y, Rinaldi E, Saraceno D, Derosa M, Czauderna P
Lancet Oncol 2017 Jan;18(1):122-131. Epub 2016 Nov 22 doi: 10.1016/S1470-2045(16)30598-8. PMID: 27884679Free PMC Article
PRETEXT II-III multifocal hepatoblastoma: significance of resection of satellite lesions irrespective of their disappearance after chemotherapy.
Qureshi SS, Bhagat M, Kembhavi S, Vora T, Ramadwar M, Talole S
Pediatr Surg Int 2015 Jun;31(6):573-9. Epub 2015 Apr 23 doi: 10.1007/s00383-015-3713-0. PMID: 25904441

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...