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Pancreatic mucinous cystadenoma

MedGen UID:
277492
Concept ID:
C1335309
Neoplastic Process
Synonyms: colloid cystadenoma of pancreas; colloid cystadenoma of the pancreas; colloidal cystadenoma of pancreas; colloidal cystadenoma of the pancreas; mucinous cystadenocarcinoma of the pancreas; Mucinous cystadenocarcinoma of the pancreas; Mucinous cystadenoma of pancreas; mucinous cystadenoma of pancreas; mucinous cystadenoma of the pancreas; pancreas mucinous cystadenoma; pancreatic colloid cystadenoma; pancreatic colloidal cystadenoma; Pancreatic mucinous cystadenocarcinoma; pancreatic mucinous cystadenocarcinoma; Pancreatic Mucinous Cystadenoma; pancreatic mucinous cystadenoma; pancreatic mucinous cystic neoplasm
SNOMED CT: Mucinous cystadenoma of pancreas (690751000119102)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0018523
Orphanet: ORPHA424053

Definition

A rare, epithelial tumor of the pancreas characterized, histologically, by columnar, mucin-producing epithelium associated with ovarian-type subepithelial stroma, which does not communicate with the pancreatic ductal system, most frequently localized to the body or tail of the pancreas. Clinically, small tumors (<3 cm) are usually asymptomatic, while large tumors typically present obstructive jaundice, a palpable abdominal mass, and may associate portal hypertension, hemobilia and diabetes mellitus. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPancreatic mucinous cystadenoma

Professional guidelines

PubMed

Yang J, Guo X, Zhang H, Zhang W, Song J, Xu H, Ma X
BMC Cancer 2019 Dec 16;19(1):1223. doi: 10.1186/s12885-019-6421-7. PMID: 31842793Free PMC Article
Dorobanţu BM, Matei E, Herlea V, Boroş M, Tivadar B, Ciurea SH
Rom J Morphol Embryol 2018;59(4):1155-1163. PMID: 30845296

Recent clinical studies

Etiology

Yang J, Guo X, Zhang H, Zhang W, Song J, Xu H, Ma X
BMC Cancer 2019 Dec 16;19(1):1223. doi: 10.1186/s12885-019-6421-7. PMID: 31842793Free PMC Article
Prost à la Denise J, Hubert D, Gaudric M, Scatton O, Soubrane O
Clin Res Hepatol Gastroenterol 2011 Nov;35(11):759-61. doi: 10.1016/j.clinre.2011.06.011. PMID: 21856266
Ishikawa K, Hirashita T, Kinoshita H, Kitano M, Matsuo S, Matsumata T, Kitano S
Surg Today 2007;37(11):1013-7. Epub 2007 Oct 25 doi: 10.1007/s00595-007-3500-1. PMID: 17952538
Ahrendt SA, Komorowski RA, Demeure MJ, Wilson SD, Pitt HA
J Gastrointest Surg 2002 Jan-Feb;6(1):66-74. doi: 10.1016/s1091-255x(01)00020-8. PMID: 11986020
Terada T, Ohta T, Sasaki M, Nakanuma Y, Kim YS
J Pathol 1996 Oct;180(2):160-5. doi: 10.1002/(SICI)1096-9896(199610)180:2<160::AID-PATH625>3.0.CO;2-A. PMID: 8976874

Diagnosis

Liu YA, Liu Y, Tu J, Shi Y, Pang J, Huang Q, Wang X, Lin Z, Zhao Y, Wang W, Peng J, Wu W
Am J Surg Pathol 2024 May 1;48(5):511-520. Epub 2024 Apr 3 doi: 10.1097/PAS.0000000000002205. PMID: 38567813Free PMC Article
Chater C, Obeid JO, Mhanna S
BMJ Case Rep 2020 Oct 7;13(10) doi: 10.1136/bcr-2020-236255. PMID: 33028569Free PMC Article
Yang J, Guo X, Zhang H, Zhang W, Song J, Xu H, Ma X
BMC Cancer 2019 Dec 16;19(1):1223. doi: 10.1186/s12885-019-6421-7. PMID: 31842793Free PMC Article
Dorobanţu BM, Matei E, Herlea V, Boroş M, Tivadar B, Ciurea SH
Rom J Morphol Embryol 2018;59(4):1155-1163. PMID: 30845296
Costa WL Jr, Mantoan H, Brito RH, Ribeiro HS, Diniz AL, Godoy AL, Farias IC, Begnami MD, Soares FA, Coimbra FJ
World J Surg Oncol 2015 Feb 25;13:78. doi: 10.1186/s12957-015-0476-y. PMID: 25888888Free PMC Article

Therapy

D'Onofrio M, Caffarri S, Zamboni G, Falconi M, Mansueto G
J Ultrasound Med 2004 Aug;23(8):1125-9. doi: 10.7863/jum.2004.23.8.1125. PMID: 15284474

Prognosis

Costa WL Jr, Mantoan H, Brito RH, Ribeiro HS, Diniz AL, Godoy AL, Farias IC, Begnami MD, Soares FA, Coimbra FJ
World J Surg Oncol 2015 Feb 25;13:78. doi: 10.1186/s12957-015-0476-y. PMID: 25888888Free PMC Article
Ishikawa K, Hirashita T, Kinoshita H, Kitano M, Matsuo S, Matsumata T, Kitano S
Surg Today 2007;37(11):1013-7. Epub 2007 Oct 25 doi: 10.1007/s00595-007-3500-1. PMID: 17952538
Kato M, Kubota K, Kita J, Shimoda M, Rokkaku K, Inaba N, Fukasawa I, Honma K
Pancreas 2005 Mar;30(2):186-8. doi: 10.1097/01.mpa.0000148512.92744.dc. PMID: 15714143
Ahrendt SA, Komorowski RA, Demeure MJ, Wilson SD, Pitt HA
J Gastrointest Surg 2002 Jan-Feb;6(1):66-74. doi: 10.1016/s1091-255x(01)00020-8. PMID: 11986020
Matsumoto T, Kitano S, Yoshida T, Bandoh T, Kakisako K, Ninomiya K, Tsuboi S, Baatar D
Surg Endosc 1999 Feb;13(2):172-3. doi: 10.1007/s004649900933. PMID: 9918625

Clinical prediction guides

Liu YA, Liu Y, Tu J, Shi Y, Pang J, Huang Q, Wang X, Lin Z, Zhao Y, Wang W, Peng J, Wu W
Am J Surg Pathol 2024 May 1;48(5):511-520. Epub 2024 Apr 3 doi: 10.1097/PAS.0000000000002205. PMID: 38567813Free PMC Article
Handra-Luca A, Fléjou JF, Rufat P, Corcos O, Belghiti J, Ruszniewski P, Degott C, Bedossa P, Couvelard A
Histopathology 2006 Jun;48(7):813-21. doi: 10.1111/j.1365-2559.2006.02444.x. PMID: 16722930
Tajiri T, Tate G, Inagaki T, Kunimura T, Inoue K, Mitsuya T, Yoshiba M, Morohoshi T
J Gastroenterol 2004;39(2):181-7. doi: 10.1007/s00535-003-1271-z. PMID: 15069627
Ahrendt SA, Komorowski RA, Demeure MJ, Wilson SD, Pitt HA
J Gastrointest Surg 2002 Jan-Feb;6(1):66-74. doi: 10.1016/s1091-255x(01)00020-8. PMID: 11986020

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