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Grade 3 Pharynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE

MedGen UID:
281329
•Concept ID:
C1556384
•
Finding
Synonym: CTCAE Grade 3 Pharynx mucositis/stomatitis (clinical exam)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 3 Pharynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE

Professional guidelines

PubMed

Pain management in patients undergoing radiation therapy for head and neck cancer - a descriptive study.
Schaller AKCS, Peterson A, Bäckryd E
Scand J Pain 2021 Apr 27;21(2):256-265. Epub 2020 Dec 10 doi: 10.1515/sjpain-2020-0067. PMID: 34387952
Validation of an instrument to measure the quality of life in children with oropharyngeal mucositis undergoing cancer treatment.
Gutiérrez-Vargas R, Velasco-Rojano E, Villasís-Keever MÁ, Portilla-Robertson J, Gutiérrez-Rodelo A, Flores-Navarro S, Juárez-Villegas LE, Zapata-Tarrés M
Bol Med Hosp Infant Mex 2019;76(1):35-43. doi: 10.24875/BMHIM.18000146. PMID: 30657465
Recombinant human epidermal growth factor treatment of radiation-induced severe oral mucositis in patients with head and neck malignancies.
Hong JP, Lee SW, Song SY, Ahn SD, Shin SS, Choi EK, Kim JH
Eur J Cancer Care (Engl) 2009 Nov;18(6):636-41. Epub 2009 Apr 23 doi: 10.1111/j.1365-2354.2008.00971.x. PMID: 19456848Free PMC Article

Recent clinical studies

Etiology

Comprehensive risk evaluation for metachronous carcinogenesis after endoscopic submucosal dissection of superficial pharyngeal squamous cell carcinoma.
Ogasawara N, Kikuchi D, Tanaka M, Ochiai Y, Okamura T, Hayasaka J, Suzuki Y, Mitsunaga Y, Nomura K, Odagiri H, Yamashita S, Matsui A, Hoteya S
Esophagus 2022 Jul;19(3):460-468. Epub 2022 Jan 31 doi: 10.1007/s10388-022-00907-8. PMID: 35099639
Evaluation of Pharyngeal Background Mucosa in Patients with Superficial Hypopharyngeal Carcinoma.
Kimura Y, Watanabe A, Shimizu Y, Goda K, Ito S, Nishimura Y, Inoue M, Taniguchi M
Laryngoscope 2021 Sep;131(9):2036-2040. Epub 2021 Mar 17 doi: 10.1002/lary.29524. PMID: 33729575
Definitive Intensity-modulated Radiation Therapy in Elderly Patients with Locally Advanced Oropharyngeal Cancer.
DE Felice F, Galdieri A, Abate G, Bulzonetti N, Musio D, Tombolini V
In Vivo 2017 May-Jun;31(3):455-459. doi: 10.21873/invivo.11083. PMID: 28438879Free PMC Article
NUTRITIONAL, MICROBIOLOGICAL, AND THERAPEUTIC FACTORS RELATED TO MUCOSITIS IN HEAD AND NECK CANCER PATIENTS: A COHORT STUDY.
Vidal-Casariego A, Fernández-Natal I, Calleja-Fernández A, Parras-Padilla T, Cano-Rodríguez I, Prieto-Alonso B, Ballesteros-Pomar MD
Nutr Hosp 2015 Sep 1;32(3):1208-13. doi: 10.3305/nh.2015.32.3.9299. PMID: 26319840
Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection.
Kuwabara T, Hiyama T, Oka S, Urabe Y, Tanaka S, Yoshihara M, Arihiro K, Shimamoto F, Chayama K
Gastrointest Endosc 2012 Dec;76(6):1095-103. Epub 2012 Sep 27 doi: 10.1016/j.gie.2012.07.032. PMID: 23022050

Diagnosis

Evaluation of Pharyngeal Background Mucosa in Patients with Superficial Hypopharyngeal Carcinoma.
Kimura Y, Watanabe A, Shimizu Y, Goda K, Ito S, Nishimura Y, Inoue M, Taniguchi M
Laryngoscope 2021 Sep;131(9):2036-2040. Epub 2021 Mar 17 doi: 10.1002/lary.29524. PMID: 33729575
Narrow Band Imaging for lingual tonsil hypertrophy and inflammation, in laryngo-pharyngeal reflux disease.
Galli J, Settimi S, Salonna G, Mele DA, De Corso E, Paludetti G
Eur Arch Otorhinolaryngol 2020 Mar;277(3):819-825. Epub 2019 Dec 19 doi: 10.1007/s00405-019-05765-2. PMID: 31858222
Definitive Intensity-modulated Radiation Therapy in Elderly Patients with Locally Advanced Oropharyngeal Cancer.
DE Felice F, Galdieri A, Abate G, Bulzonetti N, Musio D, Tombolini V
In Vivo 2017 May-Jun;31(3):455-459. doi: 10.21873/invivo.11083. PMID: 28438879Free PMC Article
NUTRITIONAL, MICROBIOLOGICAL, AND THERAPEUTIC FACTORS RELATED TO MUCOSITIS IN HEAD AND NECK CANCER PATIENTS: A COHORT STUDY.
Vidal-Casariego A, Fernández-Natal I, Calleja-Fernández A, Parras-Padilla T, Cano-Rodríguez I, Prieto-Alonso B, Ballesteros-Pomar MD
Nutr Hosp 2015 Sep 1;32(3):1208-13. doi: 10.3305/nh.2015.32.3.9299. PMID: 26319840
Oral mucositis prevention by low-level laser therapy in head-and-neck cancer patients undergoing concurrent chemoradiotherapy: a phase III randomized study.
Gouvêa de Lima A, Villar RC, de Castro G Jr, Antequera R, Gil E, Rosalmeida MC, Federico MH, Snitcovsky IM
Int J Radiat Oncol Biol Phys 2012 Jan 1;82(1):270-5. Epub 2010 Dec 14 doi: 10.1016/j.ijrobp.2010.10.012. PMID: 21163585

Therapy

Comprehensive risk evaluation for metachronous carcinogenesis after endoscopic submucosal dissection of superficial pharyngeal squamous cell carcinoma.
Ogasawara N, Kikuchi D, Tanaka M, Ochiai Y, Okamura T, Hayasaka J, Suzuki Y, Mitsunaga Y, Nomura K, Odagiri H, Yamashita S, Matsui A, Hoteya S
Esophagus 2022 Jul;19(3):460-468. Epub 2022 Jan 31 doi: 10.1007/s10388-022-00907-8. PMID: 35099639
Evaluation of Pharyngeal Background Mucosa in Patients with Superficial Hypopharyngeal Carcinoma.
Kimura Y, Watanabe A, Shimizu Y, Goda K, Ito S, Nishimura Y, Inoue M, Taniguchi M
Laryngoscope 2021 Sep;131(9):2036-2040. Epub 2021 Mar 17 doi: 10.1002/lary.29524. PMID: 33729575
Definitive Intensity-modulated Radiation Therapy in Elderly Patients with Locally Advanced Oropharyngeal Cancer.
DE Felice F, Galdieri A, Abate G, Bulzonetti N, Musio D, Tombolini V
In Vivo 2017 May-Jun;31(3):455-459. doi: 10.21873/invivo.11083. PMID: 28438879Free PMC Article
Excellent local control and survival after postoperative or definitive radiation therapy for sarcomas of the head and neck.
Andrä C, Rauch J, Li M, Ganswindt U, Belka C, Saleh-Ebrahimi L, Ballhausen H, Nachbichler SB, Roeder F
Radiat Oncol 2015 Jul 10;10:140. doi: 10.1186/s13014-015-0449-x. PMID: 26156022Free PMC Article
Oral mucositis prevention by low-level laser therapy in head-and-neck cancer patients undergoing concurrent chemoradiotherapy: a phase III randomized study.
Gouvêa de Lima A, Villar RC, de Castro G Jr, Antequera R, Gil E, Rosalmeida MC, Federico MH, Snitcovsky IM
Int J Radiat Oncol Biol Phys 2012 Jan 1;82(1):270-5. Epub 2010 Dec 14 doi: 10.1016/j.ijrobp.2010.10.012. PMID: 21163585

Prognosis

Comprehensive risk evaluation for metachronous carcinogenesis after endoscopic submucosal dissection of superficial pharyngeal squamous cell carcinoma.
Ogasawara N, Kikuchi D, Tanaka M, Ochiai Y, Okamura T, Hayasaka J, Suzuki Y, Mitsunaga Y, Nomura K, Odagiri H, Yamashita S, Matsui A, Hoteya S
Esophagus 2022 Jul;19(3):460-468. Epub 2022 Jan 31 doi: 10.1007/s10388-022-00907-8. PMID: 35099639
Bloodstream infections in head and neck cancer patients after curative-intent radiotherapy: a population-based study from the Danish Head and Neck Cancer Group database.
Jensen KH, Vogelius I, Moser CE, Andersen E, Eriksen JG, Johansen J, Farhadi M, Andersen M, Overgaard J, Friborg J
Br J Cancer 2021 Aug;125(3):458-464. Epub 2021 May 20 doi: 10.1038/s41416-021-01430-w. PMID: 34017084Free PMC Article
Evaluation of Pharyngeal Background Mucosa in Patients with Superficial Hypopharyngeal Carcinoma.
Kimura Y, Watanabe A, Shimizu Y, Goda K, Ito S, Nishimura Y, Inoue M, Taniguchi M
Laryngoscope 2021 Sep;131(9):2036-2040. Epub 2021 Mar 17 doi: 10.1002/lary.29524. PMID: 33729575
Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection.
Kuwabara T, Hiyama T, Oka S, Urabe Y, Tanaka S, Yoshihara M, Arihiro K, Shimamoto F, Chayama K
Gastrointest Endosc 2012 Dec;76(6):1095-103. Epub 2012 Sep 27 doi: 10.1016/j.gie.2012.07.032. PMID: 23022050
Dysphagia following chemoradiation for locally advanced head and neck cancer.
Nguyen NP, Moltz CC, Frank C, Vos P, Smith HJ, Karlsson U, Dutta S, Midyett FA, Barloon J, Sallah S
Ann Oncol 2004 Mar;15(3):383-8. doi: 10.1093/annonc/mdh101. PMID: 14998839

Clinical prediction guides

Comprehensive risk evaluation for metachronous carcinogenesis after endoscopic submucosal dissection of superficial pharyngeal squamous cell carcinoma.
Ogasawara N, Kikuchi D, Tanaka M, Ochiai Y, Okamura T, Hayasaka J, Suzuki Y, Mitsunaga Y, Nomura K, Odagiri H, Yamashita S, Matsui A, Hoteya S
Esophagus 2022 Jul;19(3):460-468. Epub 2022 Jan 31 doi: 10.1007/s10388-022-00907-8. PMID: 35099639
Evaluation of Pharyngeal Background Mucosa in Patients with Superficial Hypopharyngeal Carcinoma.
Kimura Y, Watanabe A, Shimizu Y, Goda K, Ito S, Nishimura Y, Inoue M, Taniguchi M
Laryngoscope 2021 Sep;131(9):2036-2040. Epub 2021 Mar 17 doi: 10.1002/lary.29524. PMID: 33729575
Definitive Intensity-modulated Radiation Therapy in Elderly Patients with Locally Advanced Oropharyngeal Cancer.
DE Felice F, Galdieri A, Abate G, Bulzonetti N, Musio D, Tombolini V
In Vivo 2017 May-Jun;31(3):455-459. doi: 10.21873/invivo.11083. PMID: 28438879Free PMC Article
Oral mucositis prevention by low-level laser therapy in head-and-neck cancer patients undergoing concurrent chemoradiotherapy: a phase III randomized study.
Gouvêa de Lima A, Villar RC, de Castro G Jr, Antequera R, Gil E, Rosalmeida MC, Federico MH, Snitcovsky IM
Int J Radiat Oncol Biol Phys 2012 Jan 1;82(1):270-5. Epub 2010 Dec 14 doi: 10.1016/j.ijrobp.2010.10.012. PMID: 21163585
Dysphagia following chemoradiation for locally advanced head and neck cancer.
Nguyen NP, Moltz CC, Frank C, Vos P, Smith HJ, Karlsson U, Dutta S, Midyett FA, Barloon J, Sallah S
Ann Oncol 2004 Mar;15(3):383-8. doi: 10.1093/annonc/mdh101. PMID: 14998839

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