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Grade 5 Stomach Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE

MedGen UID:
281348
•Concept ID:
C1556465
•
Finding
Synonym: CTCAE Grade 5 Stomach mucositis/stomatitis (functional/symptomatic)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 5 Stomach Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE

Professional guidelines

PubMed

AGA Clinical Practice Update on the Diagnosis and Management of Atrophic Gastritis: Expert Review.
Shah SC, Piazuelo MB, Kuipers EJ, Li D
Gastroenterology 2021 Oct;161(4):1325-1332.e7. Epub 2021 Aug 26 doi: 10.1053/j.gastro.2021.06.078. PMID: 34454714Free PMC Article
Diagnosis and management of Stevens-Johnson syndrome/toxic epidermal necrolysis.
Noe MH, Micheletti RG
Clin Dermatol 2020 Nov-Dec;38(6):607-612. Epub 2020 Jun 30 doi: 10.1016/j.clindermatol.2020.06.016. PMID: 33341195
Clinical Practice Guideline: Tonsillectomy in Children (Update)-Executive Summary.
Mitchell RB, Archer SM, Ishman SL, Rosenfeld RM, Coles S, Finestone SA, Friedman NR, Giordano T, Hildrew DM, Kim TW, Lloyd RM, Parikh SR, Shulman ST, Walner DL, Walsh SA, Nnacheta LC
Otolaryngol Head Neck Surg 2019 Feb;160(2):187-205. doi: 10.1177/0194599818807917. PMID: 30921525

Recent clinical studies

Etiology

The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies.
Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST
CA Cancer J Clin 2022 Jan;72(1):57-77. Epub 2021 Oct 29 doi: 10.3322/caac.21704. PMID: 34714553
Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosis.
Sroussi HY, Epstein JB, Bensadoun RJ, Saunders DP, Lalla RV, Migliorati CA, Heaivilin N, Zumsteg ZS
Cancer Med 2017 Dec;6(12):2918-2931. Epub 2017 Oct 25 doi: 10.1002/cam4.1221. PMID: 29071801Free PMC Article
Prevalences of peri-implantitis and peri-implant mucositis: systematic review and meta-analysis.
Lee CT, Huang YW, Zhu L, Weltman R
J Dent 2017 Jul;62:1-12. Epub 2017 May 3 doi: 10.1016/j.jdent.2017.04.011. PMID: 28478213
Oral pathology in inflammatory bowel disease.
Muhvić-Urek M, Tomac-Stojmenović M, Mijandrušić-Sinčić B
World J Gastroenterol 2016 Jul 7;22(25):5655-67. doi: 10.3748/wjg.v22.i25.5655. PMID: 27433081Free PMC Article
Recurrent aphthous stomatitis.
Akintoye SO, Greenberg MS
Dent Clin North Am 2014 Apr;58(2):281-97. Epub 2014 Jan 21 doi: 10.1016/j.cden.2013.12.002. PMID: 24655523Free PMC Article

Diagnosis

The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies.
Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST
CA Cancer J Clin 2022 Jan;72(1):57-77. Epub 2021 Oct 29 doi: 10.3322/caac.21704. PMID: 34714553
Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosis.
Sroussi HY, Epstein JB, Bensadoun RJ, Saunders DP, Lalla RV, Migliorati CA, Heaivilin N, Zumsteg ZS
Cancer Med 2017 Dec;6(12):2918-2931. Epub 2017 Oct 25 doi: 10.1002/cam4.1221. PMID: 29071801Free PMC Article
Prevalences of peri-implantitis and peri-implant mucositis: systematic review and meta-analysis.
Lee CT, Huang YW, Zhu L, Weltman R
J Dent 2017 Jul;62:1-12. Epub 2017 May 3 doi: 10.1016/j.jdent.2017.04.011. PMID: 28478213
Oral pathology in inflammatory bowel disease.
Muhvić-Urek M, Tomac-Stojmenović M, Mijandrušić-Sinčić B
World J Gastroenterol 2016 Jul 7;22(25):5655-67. doi: 10.3748/wjg.v22.i25.5655. PMID: 27433081Free PMC Article
Recurrent aphthous stomatitis.
Akintoye SO, Greenberg MS
Dent Clin North Am 2014 Apr;58(2):281-97. Epub 2014 Jan 21 doi: 10.1016/j.cden.2013.12.002. PMID: 24655523Free PMC Article

Therapy

The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies.
Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST
CA Cancer J Clin 2022 Jan;72(1):57-77. Epub 2021 Oct 29 doi: 10.3322/caac.21704. PMID: 34714553
Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosis.
Sroussi HY, Epstein JB, Bensadoun RJ, Saunders DP, Lalla RV, Migliorati CA, Heaivilin N, Zumsteg ZS
Cancer Med 2017 Dec;6(12):2918-2931. Epub 2017 Oct 25 doi: 10.1002/cam4.1221. PMID: 29071801Free PMC Article
Prevalences of peri-implantitis and peri-implant mucositis: systematic review and meta-analysis.
Lee CT, Huang YW, Zhu L, Weltman R
J Dent 2017 Jul;62:1-12. Epub 2017 May 3 doi: 10.1016/j.jdent.2017.04.011. PMID: 28478213
Oral pathology in inflammatory bowel disease.
Muhvić-Urek M, Tomac-Stojmenović M, Mijandrušić-Sinčić B
World J Gastroenterol 2016 Jul 7;22(25):5655-67. doi: 10.3748/wjg.v22.i25.5655. PMID: 27433081Free PMC Article
Peri-implant health and disease. A systematic review of current epidemiology.
Derks J, Tomasi C
J Clin Periodontol 2015 Apr;42 Suppl 16:S158-71. doi: 10.1111/jcpe.12334. PMID: 25495683

Prognosis

The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies.
Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST
CA Cancer J Clin 2022 Jan;72(1):57-77. Epub 2021 Oct 29 doi: 10.3322/caac.21704. PMID: 34714553
Bullous Drug Reactions.
Mockenhaupt M
Acta Derm Venereol 2020 Feb 12;100(5):adv00057. doi: 10.2340/00015555-3408. PMID: 32039459Free PMC Article
Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosis.
Sroussi HY, Epstein JB, Bensadoun RJ, Saunders DP, Lalla RV, Migliorati CA, Heaivilin N, Zumsteg ZS
Cancer Med 2017 Dec;6(12):2918-2931. Epub 2017 Oct 25 doi: 10.1002/cam4.1221. PMID: 29071801Free PMC Article
Palatal ulceration.
Sardana K, Bansal S
Clin Dermatol 2014 Nov-Dec;32(6):827-38. Epub 2014 Mar 1 doi: 10.1016/j.clindermatol.2014.02.023. PMID: 25441477
SCORTEN: a severity-of-illness score for toxic epidermal necrolysis.
Bastuji-Garin S, Fouchard N, Bertocchi M, Roujeau JC, Revuz J, Wolkenstein P
J Invest Dermatol 2000 Aug;115(2):149-53. doi: 10.1046/j.1523-1747.2000.00061.x. PMID: 10951229

Clinical prediction guides

From Pathogenesis to Intervention: The Importance of the Microbiome in Oral Mucositis.
Bruno JS, Al-Qadami GH, Laheij AMGA, Bossi P, Fregnani ER, Wardill HR
Int J Mol Sci 2023 May 5;24(9) doi: 10.3390/ijms24098274. PMID: 37175980Free PMC Article
Management of Denture Infection with Phytomedicine.
Anitha KV, Rajkumar K
Infect Disord Drug Targets 2023;23(2):e290822208190. doi: 10.2174/1871526522666220829160234. PMID: 36043755
The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies.
Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST
CA Cancer J Clin 2022 Jan;72(1):57-77. Epub 2021 Oct 29 doi: 10.3322/caac.21704. PMID: 34714553
Endoscopic Kyoto classification of Helicobacter pylori infection and gastric cancer risk diagnosis.
Toyoshima O, Nishizawa T, Koike K
World J Gastroenterol 2020 Feb 7;26(5):466-477. doi: 10.3748/wjg.v26.i5.466. PMID: 32089624Free PMC Article
Noma (cancrum oris): An unresolved global challenge.
Feller L, Khammissa RAG, Altini M, Lemmer J
Periodontol 2000 2019 Jun;80(1):189-199. doi: 10.1111/prd.12275. PMID: 31090145Free PMC Article

Recent systematic reviews

Systemic interventions for treatment of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome.
Jacobsen A, Olabi B, Langley A, Beecker J, Mutter E, Shelley A, Worley B, Ramsay T, Saavedra A, Parker R, Stewart F, Pardo Pardo J
Cochrane Database Syst Rev 2022 Mar 11;3(3):CD013130. doi: 10.1002/14651858.CD013130.pub2. PMID: 35274741Free PMC Article
Prevalences of peri-implantitis and peri-implant mucositis: systematic review and meta-analysis.
Lee CT, Huang YW, Zhu L, Weltman R
J Dent 2017 Jul;62:1-12. Epub 2017 May 3 doi: 10.1016/j.jdent.2017.04.011. PMID: 28478213
Systemic Immunomodulating Therapies for Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review and Meta-analysis.
Zimmermann S, Sekula P, Venhoff M, Motschall E, Knaus J, Schumacher M, Mockenhaupt M
JAMA Dermatol 2017 Jun 1;153(6):514-522. doi: 10.1001/jamadermatol.2016.5668. PMID: 28329382Free PMC Article
Peri-implant health and disease. A systematic review of current epidemiology.
Derks J, Tomasi C
J Clin Periodontol 2015 Apr;42 Suppl 16:S158-71. doi: 10.1111/jcpe.12334. PMID: 25495683
Primary low-grade and high-grade gastric MALT-lymphoma presentation.
Zullo A, Hassan C, Andriani A, Cristofari F, Cardinale V, Spinelli GP, Tomao S, Morini S
J Clin Gastroenterol 2010 May-Jun;44(5):340-4. doi: 10.1097/MCG.0b013e3181b4b1ab. PMID: 19745757

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