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Grade 3 Rectum Mucositis or Stomatitis by Clinical Examination Classification, CTCAE

MedGen UID:
284590
•Concept ID:
C1556390
•
Finding
Synonym: CTCAE Grade 3 Rectum mucositis/stomatitis (clinical exam)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 3 Rectum Mucositis or Stomatitis by Clinical Examination Classification, CTCAE

Professional guidelines

PubMed

Erudition from primary posterior sagittal anorectoplasty for anorectal malformations over two decades.
Sharma S
Pediatr Surg Int 2023 Oct 1;39(1):277. doi: 10.1007/s00383-023-05559-y. PMID: 37777986
Management of colorectal T1 carcinoma treated by endoscopic resection.
Saitoh Y, Inaba Y, Sasaki T, Sugiyama R, Sukegawa R, Fujiya M
Dig Endosc 2016 Apr;28(3):324-9. Epub 2015 Sep 6 doi: 10.1111/den.12503. PMID: 26076802
Risk analysis of submucosal invasive rectal carcinomas for lymph node metastasis to expand indication criteria for endoscopic resection.
Oka S, Tanaka S, Nakadoi K, Kanao H, Chayama K
Dig Endosc 2013 May;25 Suppl 2:21-5. doi: 10.1111/den.12089. PMID: 23617644

Recent clinical studies

Etiology

Recurrence and Survival of Neuroendocrine Neoplasms of the Rectum: Single-Center Experience.
Storino A, Wong D, Ore AS, Gaytan-Fuentes IA, Fabrizio A, Cataldo T, Messaris E
J Gastrointest Surg 2021 Sep;25(9):2398-2400. Epub 2020 Dec 2 doi: 10.1007/s11605-020-04854-6. PMID: 33269457
Efficacy and Safety of Etrasimod in a Phase 2 Randomized Trial of Patients With Ulcerative Colitis.
Sandborn WJ, Peyrin-Biroulet L, Zhang J, Chiorean M, Vermeire S, Lee SD, Kühbacher T, Yacyshyn B, Cabell CH, Naik SU, Klassen P, Panés J
Gastroenterology 2020 Feb;158(3):550-561. Epub 2019 Nov 9 doi: 10.1053/j.gastro.2019.10.035. PMID: 31711921
Management of colorectal T1 carcinoma treated by endoscopic resection.
Saitoh Y, Inaba Y, Sasaki T, Sugiyama R, Sukegawa R, Fujiya M
Dig Endosc 2016 Apr;28(3):324-9. Epub 2015 Sep 6 doi: 10.1111/den.12503. PMID: 26076802
Risk analysis of submucosal invasive rectal carcinomas for lymph node metastasis to expand indication criteria for endoscopic resection.
Oka S, Tanaka S, Nakadoi K, Kanao H, Chayama K
Dig Endosc 2013 May;25 Suppl 2:21-5. doi: 10.1111/den.12089. PMID: 23617644
Lymphoma of the gastrointestinal tract.
Crump M, Gospodarowicz M, Shepherd FA
Semin Oncol 1999 Jun;26(3):324-37. PMID: 10375089

Diagnosis

Recurrence and Survival of Neuroendocrine Neoplasms of the Rectum: Single-Center Experience.
Storino A, Wong D, Ore AS, Gaytan-Fuentes IA, Fabrizio A, Cataldo T, Messaris E
J Gastrointest Surg 2021 Sep;25(9):2398-2400. Epub 2020 Dec 2 doi: 10.1007/s11605-020-04854-6. PMID: 33269457
Efficacy and Safety of Etrasimod in a Phase 2 Randomized Trial of Patients With Ulcerative Colitis.
Sandborn WJ, Peyrin-Biroulet L, Zhang J, Chiorean M, Vermeire S, Lee SD, Kühbacher T, Yacyshyn B, Cabell CH, Naik SU, Klassen P, Panés J
Gastroenterology 2020 Feb;158(3):550-561. Epub 2019 Nov 9 doi: 10.1053/j.gastro.2019.10.035. PMID: 31711921
Intramucosal colorectal carcinoma with invasion of the lamina propria: a study by the Japanese Society for Cancer of the Colon and Rectum.
Kojima M, Shimazaki H, Iwaya K, Nakamura T, Kawachi H, Ichikawa K, Sekine S, Ishiguro S, Shimoda T, Kushima R, Yao T, Fujimori T, Hase K, Watanabe T, Sugihara K, Lauwers GY, Ochiai A
Hum Pathol 2017 Aug;66:230-237. Epub 2017 Jul 13 doi: 10.1016/j.humpath.2017.04.031. PMID: 28711649
Management of colorectal T1 carcinoma treated by endoscopic resection.
Saitoh Y, Inaba Y, Sasaki T, Sugiyama R, Sukegawa R, Fujiya M
Dig Endosc 2016 Apr;28(3):324-9. Epub 2015 Sep 6 doi: 10.1111/den.12503. PMID: 26076802
Lymphoma of the gastrointestinal tract.
Crump M, Gospodarowicz M, Shepherd FA
Semin Oncol 1999 Jun;26(3):324-37. PMID: 10375089

Therapy

Acute and Late Rectal Toxicity Following Hypofractionated Radiotherapy in Patients With Prostate Cancer: Results of a Prospective Study.
Kounadis G, Syrigos N, Kougioumtzopoulou A, Bamias G, Kotteas I, Papatheodoridis G, Grapsa D
In Vivo 2022 Jul-Aug;36(4):1875-1880. doi: 10.21873/invivo.12906. PMID: 35738620Free PMC Article
Randomized Phase II Trial of Polyphenon E versus Placebo in Patients at High Risk of Recurrent Colonic Neoplasia.
Sinicrope FA, Viggiano TR, Buttar NS, Song LMWK, Schroeder KW, Kraichely RE, Larson MV, Sedlack RE, Kisiel JB, Gostout CJ, Kalaiger AM, Patai ÁV, Della'Zanna G, Umar A, Limburg PJ, Meyers JP, Foster NR, Yang CS, Sontag S
Cancer Prev Res (Phila) 2021 May;14(5):573-580. Epub 2021 Mar 1 doi: 10.1158/1940-6207.CAPR-20-0598. PMID: 33648940Free PMC Article
Efficacy and Safety of Etrasimod in a Phase 2 Randomized Trial of Patients With Ulcerative Colitis.
Sandborn WJ, Peyrin-Biroulet L, Zhang J, Chiorean M, Vermeire S, Lee SD, Kühbacher T, Yacyshyn B, Cabell CH, Naik SU, Klassen P, Panés J
Gastroenterology 2020 Feb;158(3):550-561. Epub 2019 Nov 9 doi: 10.1053/j.gastro.2019.10.035. PMID: 31711921
A Phase I Trial of Berberine in Chinese with Ulcerative Colitis.
Xu L, Zhang Y, Xue X, Liu J, Li ZS, Yang GY, Song Y, Pan Y, Ma Y, Hu S, Wen A, Jia Y, Rodriguez LM, Tull MB, Benante K, Khan SA, Cao Y, Jovanovic B, Richmond E, Umar A, Bergan R, Wu K
Cancer Prev Res (Phila) 2020 Jan;13(1):117-126. Epub 2019 Oct 16 doi: 10.1158/1940-6207.CAPR-19-0258. PMID: 31619442
Lymphoma of the gastrointestinal tract.
Crump M, Gospodarowicz M, Shepherd FA
Semin Oncol 1999 Jun;26(3):324-37. PMID: 10375089

Prognosis

Erudition from primary posterior sagittal anorectoplasty for anorectal malformations over two decades.
Sharma S
Pediatr Surg Int 2023 Oct 1;39(1):277. doi: 10.1007/s00383-023-05559-y. PMID: 37777986
Clinical outcomes and risk factors associated with poor prognosis after endoscopic resection of 10-20 mm rectal neuroendocrine tumors: a multicenter, retrospective study of 10-year experience.
Goo JJ, Baek DH, Kim HW, Lee HS, Lee JY, Park SB, Song GA, Lee SH, Lee JH; Busan Ulsan Gyeongnam Intestinal Study Group Society (BIGS)
Surg Endosc 2023 Jul;37(7):5196-5204. Epub 2023 Mar 22 doi: 10.1007/s00464-023-09999-4. PMID: 36947224
Colonic Adenomatous Polyps Involving Submucosal Lymphoglandular Complexes: A Diagnostic Pitfall.
Lee HE, Wu TT, Chandan VS, Torbenson MS, Mounajjed T
Am J Surg Pathol 2018 Aug;42(8):1083-1089. doi: 10.1097/PAS.0000000000001081. PMID: 29738362
Management of colorectal T1 carcinoma treated by endoscopic resection.
Saitoh Y, Inaba Y, Sasaki T, Sugiyama R, Sukegawa R, Fujiya M
Dig Endosc 2016 Apr;28(3):324-9. Epub 2015 Sep 6 doi: 10.1111/den.12503. PMID: 26076802
Risk analysis of submucosal invasive rectal carcinomas for lymph node metastasis to expand indication criteria for endoscopic resection.
Oka S, Tanaka S, Nakadoi K, Kanao H, Chayama K
Dig Endosc 2013 May;25 Suppl 2:21-5. doi: 10.1111/den.12089. PMID: 23617644

Clinical prediction guides

Endoscopic submucosal dissection for removal of large colorectal neoplasias in an outpatient setting: a single-center series of 660 procedures in Sweden.
Tidehag V, Törnqvist B, Pekkari K, Marsk R
Gastrointest Endosc 2022 Jul;96(1):101-107. Epub 2022 Feb 22 doi: 10.1016/j.gie.2022.02.017. PMID: 35217016
Efficacy and Safety of Etrasimod in a Phase 2 Randomized Trial of Patients With Ulcerative Colitis.
Sandborn WJ, Peyrin-Biroulet L, Zhang J, Chiorean M, Vermeire S, Lee SD, Kühbacher T, Yacyshyn B, Cabell CH, Naik SU, Klassen P, Panés J
Gastroenterology 2020 Feb;158(3):550-561. Epub 2019 Nov 9 doi: 10.1053/j.gastro.2019.10.035. PMID: 31711921
A Phase I Trial of Berberine in Chinese with Ulcerative Colitis.
Xu L, Zhang Y, Xue X, Liu J, Li ZS, Yang GY, Song Y, Pan Y, Ma Y, Hu S, Wen A, Jia Y, Rodriguez LM, Tull MB, Benante K, Khan SA, Cao Y, Jovanovic B, Richmond E, Umar A, Bergan R, Wu K
Cancer Prev Res (Phila) 2020 Jan;13(1):117-126. Epub 2019 Oct 16 doi: 10.1158/1940-6207.CAPR-19-0258. PMID: 31619442
Colonic Adenomatous Polyps Involving Submucosal Lymphoglandular Complexes: A Diagnostic Pitfall.
Lee HE, Wu TT, Chandan VS, Torbenson MS, Mounajjed T
Am J Surg Pathol 2018 Aug;42(8):1083-1089. doi: 10.1097/PAS.0000000000001081. PMID: 29738362
Intramucosal colorectal carcinoma with invasion of the lamina propria: a study by the Japanese Society for Cancer of the Colon and Rectum.
Kojima M, Shimazaki H, Iwaya K, Nakamura T, Kawachi H, Ichikawa K, Sekine S, Ishiguro S, Shimoda T, Kushima R, Yao T, Fujimori T, Hase K, Watanabe T, Sugihara K, Lauwers GY, Ochiai A
Hum Pathol 2017 Aug;66:230-237. Epub 2017 Jul 13 doi: 10.1016/j.humpath.2017.04.031. PMID: 28711649

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