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Grade 4 Anus Mucositis or Stomatitis by Clinical Examination Classification, CTCAE

MedGen UID:
286842
•Concept ID:
C1560537
•
Finding
Synonym: CTCAE Grade 4 Anus Mucositis/stomatitis (clinical exam)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 4 Anus Mucositis or Stomatitis by Clinical Examination Classification, CTCAE

Professional guidelines

PubMed

Erudition from primary posterior sagittal anorectoplasty for anorectal malformations over two decades.
Sharma S
Pediatr Surg Int 2023 Oct 1;39(1):277. doi: 10.1007/s00383-023-05559-y. PMID: 37777986
Twenty-year experience in the management of squamous cell anal canal carcinoma with interstitial brachytherapy.
López Guerra JL, Lozano AJ, Pera J, Gutiérrez C, Cambray M, Ferrer F, Guedea F
Clin Transl Oncol 2011 Jul;13(7):472-9. doi: 10.1007/s12094-011-0684-z. PMID: 21775274
Synchronous radiotherapy and chemotherapy in the treatment of nasopharyngeal carcinoma.
Turner SL, Tiver KW
Int J Radiat Oncol Biol Phys 1993 Sep 30;27(2):371-7. doi: 10.1016/0360-3016(93)90249-u. PMID: 8407412

Recent clinical studies

Etiology

Erudition from primary posterior sagittal anorectoplasty for anorectal malformations over two decades.
Sharma S
Pediatr Surg Int 2023 Oct 1;39(1):277. doi: 10.1007/s00383-023-05559-y. PMID: 37777986
High prevalence and incidence of HPV-related anal cancer precursor lesions in HIV-positive women in the late HAART era.
Hidalgo-Tenorio C, de Jesus SE, Esquivias J, Pasquau J
Enferm Infecc Microbiol Clin (Engl Ed) 2018 Nov;36(9):555-562. Epub 2017 Dec 6 doi: 10.1016/j.eimc.2017.10.014. PMID: 29208455
Expression of proliferative biomarkers in anal intraepithelial neoplasia of HIV-positive men.
Kreuter A, Jesse M, Potthoff A, Brockmeyer NH, Gambichler T, Stücker M, Bechara FG, Pfister H, Wieland U
J Am Acad Dermatol 2010 Sep;63(3):490-8. Epub 2009 Dec 16 doi: 10.1016/j.jaad.2009.08.043. PMID: 20006407
Gracilis muscle transposition in the treatment of faecal incontinence.
Sielezneff I, Bauer S, Bulgare JC, Sarles JC
Int J Colorectal Dis 1996;11(1):15-8. doi: 10.1007/BF00418849. PMID: 8919335
Leiomyosarcoma of the rectum and anal canal.
Tjandra JJ, Antoniuk PM, Webb B, Petras RE, Fazio VW
Aust N Z J Surg 1993 Sep;63(9):703-9. doi: 10.1111/j.1445-2197.1993.tb00495.x. PMID: 8363480

Diagnosis

Prospective Randomized Study on Stapled Anopexy Height and Its Influence on Recurrence for Hemorrhoidal Disease Treatment.
Hidalgo-Grau LA, Piedrafita-Serra E, Ruiz-Edo N, Llorca-Cardeñosa S, Heredia-Budó A, Estrada-Ferrer O, Suñol-Sala X
World J Surg 2020 Nov;44(11):3936-3942. doi: 10.1007/s00268-020-05676-y. PMID: 32647985
High-resolution anoscopy: clinical features of anal intraepithelial neoplasia in HIV-positive men.
Richel O, Hallensleben ND, Kreuter A, van Noesel CJ, Prins JM, de Vries HJ
Dis Colon Rectum 2013 Nov;56(11):1237-42. doi: 10.1097/DCR.0b013e3182a53568. PMID: 24104998
Clinical significance of indefinite for dysplasia on pouch biopsy in patients with underlying inflammatory bowel disease.
Liu ZX, Liu XL, Patil DT, Lian L, Kiran RP, Remzi FH, Ni RZ, Shen B
J Gastrointest Surg 2012 Mar;16(3):562-71. Epub 2011 Nov 29 doi: 10.1007/s11605-011-1779-0. PMID: 22125168
Expression of proliferative biomarkers in anal intraepithelial neoplasia of HIV-positive men.
Kreuter A, Jesse M, Potthoff A, Brockmeyer NH, Gambichler T, Stücker M, Bechara FG, Pfister H, Wieland U
J Am Acad Dermatol 2010 Sep;63(3):490-8. Epub 2009 Dec 16 doi: 10.1016/j.jaad.2009.08.043. PMID: 20006407
Synchronous radiotherapy and chemotherapy in the treatment of nasopharyngeal carcinoma.
Turner SL, Tiver KW
Int J Radiat Oncol Biol Phys 1993 Sep 30;27(2):371-7. doi: 10.1016/0360-3016(93)90249-u. PMID: 8407412

Therapy

Prospective Randomized Study on Stapled Anopexy Height and Its Influence on Recurrence for Hemorrhoidal Disease Treatment.
Hidalgo-Grau LA, Piedrafita-Serra E, Ruiz-Edo N, Llorca-Cardeñosa S, Heredia-Budó A, Estrada-Ferrer O, Suñol-Sala X
World J Surg 2020 Nov;44(11):3936-3942. doi: 10.1007/s00268-020-05676-y. PMID: 32647985
Doppler-guided hemorrhoidal artery ligation with hemorrhoidopexy: source and prevention of postoperative pain.
Rubbini M, Tartari V
Int J Colorectal Dis 2015 May;30(5):625-30. Epub 2015 Feb 5 doi: 10.1007/s00384-015-2148-3. PMID: 25652879
Transanal haemorrhoidal dearterialisation with mucopexy versus stapler haemorrhoidopexy: a randomised trial with long-term follow-up.
Lucarelli P, Picchio M, Caporossi M, De Angelis F, Di Filippo A, Stipa F, Spaziani E
Ann R Coll Surg Engl 2013 May;95(4):246-51. doi: 10.1308/003588413X13511609958136. PMID: 23676807Free PMC Article
Twenty-year experience in the management of squamous cell anal canal carcinoma with interstitial brachytherapy.
López Guerra JL, Lozano AJ, Pera J, Gutiérrez C, Cambray M, Ferrer F, Guedea F
Clin Transl Oncol 2011 Jul;13(7):472-9. doi: 10.1007/s12094-011-0684-z. PMID: 21775274
Synchronous radiotherapy and chemotherapy in the treatment of nasopharyngeal carcinoma.
Turner SL, Tiver KW
Int J Radiat Oncol Biol Phys 1993 Sep 30;27(2):371-7. doi: 10.1016/0360-3016(93)90249-u. PMID: 8407412

Prognosis

Erudition from primary posterior sagittal anorectoplasty for anorectal malformations over two decades.
Sharma S
Pediatr Surg Int 2023 Oct 1;39(1):277. doi: 10.1007/s00383-023-05559-y. PMID: 37777986
High prevalence and incidence of HPV-related anal cancer precursor lesions in HIV-positive women in the late HAART era.
Hidalgo-Tenorio C, de Jesus SE, Esquivias J, Pasquau J
Enferm Infecc Microbiol Clin (Engl Ed) 2018 Nov;36(9):555-562. Epub 2017 Dec 6 doi: 10.1016/j.eimc.2017.10.014. PMID: 29208455
High-resolution anoscopy: clinical features of anal intraepithelial neoplasia in HIV-positive men.
Richel O, Hallensleben ND, Kreuter A, van Noesel CJ, Prins JM, de Vries HJ
Dis Colon Rectum 2013 Nov;56(11):1237-42. doi: 10.1097/DCR.0b013e3182a53568. PMID: 24104998
Gracilis muscle transposition in the treatment of faecal incontinence.
Sielezneff I, Bauer S, Bulgare JC, Sarles JC
Int J Colorectal Dis 1996;11(1):15-8. doi: 10.1007/BF00418849. PMID: 8919335
Leiomyosarcoma of the rectum and anal canal.
Tjandra JJ, Antoniuk PM, Webb B, Petras RE, Fazio VW
Aust N Z J Surg 1993 Sep;63(9):703-9. doi: 10.1111/j.1445-2197.1993.tb00495.x. PMID: 8363480

Clinical prediction guides

TRANSANAL HAEMORRHOIDAL DEARTERIALIZATION WITH MUCOPEXY (THD-M) FOR TREATMENT OF HEMORRHOIDS: IS IT APPLICABLE IN ALL GRADES? BRAZILIAN MULTICENTER STUDY.
Sobrado CW, Klajner S, Hora JAB, Mello A, Silva FMLD, Frugis MO, Sobrado LF
Arq Bras Cir Dig 2020;33(2):e1504. Epub 2020 Aug 24 doi: 10.1590/0102-672020190001e1504. PMID: 32844877Free PMC Article
High prevalence and incidence of HPV-related anal cancer precursor lesions in HIV-positive women in the late HAART era.
Hidalgo-Tenorio C, de Jesus SE, Esquivias J, Pasquau J
Enferm Infecc Microbiol Clin (Engl Ed) 2018 Nov;36(9):555-562. Epub 2017 Dec 6 doi: 10.1016/j.eimc.2017.10.014. PMID: 29208455
Doppler-guided hemorrhoidal artery ligation with hemorrhoidopexy: source and prevention of postoperative pain.
Rubbini M, Tartari V
Int J Colorectal Dis 2015 May;30(5):625-30. Epub 2015 Feb 5 doi: 10.1007/s00384-015-2148-3. PMID: 25652879
High-resolution anoscopy: clinical features of anal intraepithelial neoplasia in HIV-positive men.
Richel O, Hallensleben ND, Kreuter A, van Noesel CJ, Prins JM, de Vries HJ
Dis Colon Rectum 2013 Nov;56(11):1237-42. doi: 10.1097/DCR.0b013e3182a53568. PMID: 24104998
Anal continence after rectocele repair.
Ayabaca SM, Zbar AP, Pescatori M
Dis Colon Rectum 2002 Jan;45(1):63-9. doi: 10.1007/s10350-004-6115-2. PMID: 11786766

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