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Grade 5 Anus Mucositis or Stomatitis by Clinical Examination Classification, CTCAE

MedGen UID:
286843
•Concept ID:
C1560538
•
Finding
Synonym: CTCAE Grade 5 Anus Mucositis/stomatitis (clinical exam)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 5 Anus Mucositis or Stomatitis by Clinical Examination Classification, CTCAE

Professional guidelines

PubMed

Erudition from primary posterior sagittal anorectoplasty for anorectal malformations over two decades.
Sharma S
Pediatr Surg Int 2023 Oct 1;39(1):277. doi: 10.1007/s00383-023-05559-y. PMID: 37777986
Doppler-guided hemorrhoidal laser procedure for the treatment of symptomatic hemorrhoids: experimental background and short-term clinical results of a new mini-invasive treatment.
Giamundo P, Cecchetti W, Esercizio L, Fantino G, Geraci M, Lombezzi R, Pittaluga M, Tibaldi L, Torre G, Valente M
Surg Endosc 2011 May;25(5):1369-75. Epub 2010 Oct 26 doi: 10.1007/s00464-010-1370-x. PMID: 20976499
Synchronous radiotherapy and chemotherapy in the treatment of nasopharyngeal carcinoma.
Turner SL, Tiver KW
Int J Radiat Oncol Biol Phys 1993 Sep 30;27(2):371-7. doi: 10.1016/0360-3016(93)90249-u. PMID: 8407412

Recent clinical studies

Etiology

Erudition from primary posterior sagittal anorectoplasty for anorectal malformations over two decades.
Sharma S
Pediatr Surg Int 2023 Oct 1;39(1):277. doi: 10.1007/s00383-023-05559-y. PMID: 37777986
A Pilot Study of the Immunologic, Virologic, and Pathologic Consequences of Intra-anal 5% Imiquimod in HIV-1-Infected Men With High-Grade Squamous Intraepithelial Lesions.
Cranston RD, Baker JR, Siegel A, Brand RM, Janocko L, McGowan I
Dis Colon Rectum 2018 Mar;61(3):298-305. doi: 10.1097/DCR.0000000000000991. PMID: 29360679
Pathophysiology of late anorectal dysfunction following external beam radiotherapy for prostate cancer.
Petersen SE, Bregendahl S, Langschwager M, Laurberg S, Brock C, Drewes AM, Krogh K, Høyer M, Lundby L
Acta Oncol 2014 Oct;53(10):1398-404. Epub 2014 Jun 24 doi: 10.3109/0284186X.2014.926029. PMID: 24960583
Expression of proliferative biomarkers in anal intraepithelial neoplasia of HIV-positive men.
Kreuter A, Jesse M, Potthoff A, Brockmeyer NH, Gambichler T, Stücker M, Bechara FG, Pfister H, Wieland U
J Am Acad Dermatol 2010 Sep;63(3):490-8. Epub 2009 Dec 16 doi: 10.1016/j.jaad.2009.08.043. PMID: 20006407
Gracilis muscle transposition in the treatment of faecal incontinence.
Sielezneff I, Bauer S, Bulgare JC, Sarles JC
Int J Colorectal Dis 1996;11(1):15-8. doi: 10.1007/BF00418849. PMID: 8919335

Diagnosis

Prospective Randomized Study on Stapled Anopexy Height and Its Influence on Recurrence for Hemorrhoidal Disease Treatment.
Hidalgo-Grau LA, Piedrafita-Serra E, Ruiz-Edo N, Llorca-Cardeñosa S, Heredia-Budó A, Estrada-Ferrer O, Suñol-Sala X
World J Surg 2020 Nov;44(11):3936-3942. doi: 10.1007/s00268-020-05676-y. PMID: 32647985
Pathophysiology of late anorectal dysfunction following external beam radiotherapy for prostate cancer.
Petersen SE, Bregendahl S, Langschwager M, Laurberg S, Brock C, Drewes AM, Krogh K, Høyer M, Lundby L
Acta Oncol 2014 Oct;53(10):1398-404. Epub 2014 Jun 24 doi: 10.3109/0284186X.2014.926029. PMID: 24960583
High-resolution anoscopy: clinical features of anal intraepithelial neoplasia in HIV-positive men.
Richel O, Hallensleben ND, Kreuter A, van Noesel CJ, Prins JM, de Vries HJ
Dis Colon Rectum 2013 Nov;56(11):1237-42. doi: 10.1097/DCR.0b013e3182a53568. PMID: 24104998
Clinical significance of indefinite for dysplasia on pouch biopsy in patients with underlying inflammatory bowel disease.
Liu ZX, Liu XL, Patil DT, Lian L, Kiran RP, Remzi FH, Ni RZ, Shen B
J Gastrointest Surg 2012 Mar;16(3):562-71. Epub 2011 Nov 29 doi: 10.1007/s11605-011-1779-0. PMID: 22125168
Expression of proliferative biomarkers in anal intraepithelial neoplasia of HIV-positive men.
Kreuter A, Jesse M, Potthoff A, Brockmeyer NH, Gambichler T, Stücker M, Bechara FG, Pfister H, Wieland U
J Am Acad Dermatol 2010 Sep;63(3):490-8. Epub 2009 Dec 16 doi: 10.1016/j.jaad.2009.08.043. PMID: 20006407

Therapy

Pilot trial of topical MTS‑01 application to reduce dermatitis in patients receiving chemoradiotherapy for stage I‑III carcinoma of the anal canal.
Citrin D, Valle L, Camphausen K, Cooley-Zgela T, Smart D, Yao M, Mitchell JB, Thompson W, Sereti I, Uldrick T
Int J Oncol 2022 Jun;60(6) Epub 2022 Apr 19 doi: 10.3892/ijo.2022.5358. PMID: 35438186Free PMC Article
Prospective Randomized Study on Stapled Anopexy Height and Its Influence on Recurrence for Hemorrhoidal Disease Treatment.
Hidalgo-Grau LA, Piedrafita-Serra E, Ruiz-Edo N, Llorca-Cardeñosa S, Heredia-Budó A, Estrada-Ferrer O, Suñol-Sala X
World J Surg 2020 Nov;44(11):3936-3942. doi: 10.1007/s00268-020-05676-y. PMID: 32647985
A Pilot Study of the Immunologic, Virologic, and Pathologic Consequences of Intra-anal 5% Imiquimod in HIV-1-Infected Men With High-Grade Squamous Intraepithelial Lesions.
Cranston RD, Baker JR, Siegel A, Brand RM, Janocko L, McGowan I
Dis Colon Rectum 2018 Mar;61(3):298-305. doi: 10.1097/DCR.0000000000000991. PMID: 29360679
Doppler-guided hemorrhoidal artery ligation with hemorrhoidopexy: source and prevention of postoperative pain.
Rubbini M, Tartari V
Int J Colorectal Dis 2015 May;30(5):625-30. Epub 2015 Feb 5 doi: 10.1007/s00384-015-2148-3. PMID: 25652879
Genital human papillomavirus infections: current and prospective therapies.
Stanley MA
J Gen Virol 2012 Apr;93(Pt 4):681-691. Epub 2012 Feb 8 doi: 10.1099/vir.0.039677-0. PMID: 22323530

Prognosis

Erudition from primary posterior sagittal anorectoplasty for anorectal malformations over two decades.
Sharma S
Pediatr Surg Int 2023 Oct 1;39(1):277. doi: 10.1007/s00383-023-05559-y. PMID: 37777986
Pathophysiology of late anorectal dysfunction following external beam radiotherapy for prostate cancer.
Petersen SE, Bregendahl S, Langschwager M, Laurberg S, Brock C, Drewes AM, Krogh K, Høyer M, Lundby L
Acta Oncol 2014 Oct;53(10):1398-404. Epub 2014 Jun 24 doi: 10.3109/0284186X.2014.926029. PMID: 24960583
High-resolution anoscopy: clinical features of anal intraepithelial neoplasia in HIV-positive men.
Richel O, Hallensleben ND, Kreuter A, van Noesel CJ, Prins JM, de Vries HJ
Dis Colon Rectum 2013 Nov;56(11):1237-42. doi: 10.1097/DCR.0b013e3182a53568. PMID: 24104998
Gracilis muscle transposition in the treatment of faecal incontinence.
Sielezneff I, Bauer S, Bulgare JC, Sarles JC
Int J Colorectal Dis 1996;11(1):15-8. doi: 10.1007/BF00418849. PMID: 8919335
Leiomyosarcoma of the rectum and anal canal.
Tjandra JJ, Antoniuk PM, Webb B, Petras RE, Fazio VW
Aust N Z J Surg 1993 Sep;63(9):703-9. doi: 10.1111/j.1445-2197.1993.tb00495.x. PMID: 8363480

Clinical prediction guides

Löwenstein-Buschke: Clinicopathologic Analysis of 78 Cases of Large and Giant Condyloma Acuminata of the Anus.
Taskin OC, Pehlivanoglu B, Reid MD, Friedman T, Lee M, Tadros TS, Bandyopadhyay S, Akinfolarin J, Armutlu A, Basturk O, Adsay V
Turk Patoloji Derg 2021;37(1):18-25. doi: 10.5146/tjpath.2020.01508. PMID: 33021736Free PMC Article
TRANSANAL HAEMORRHOIDAL DEARTERIALIZATION WITH MUCOPEXY (THD-M) FOR TREATMENT OF HEMORRHOIDS: IS IT APPLICABLE IN ALL GRADES? BRAZILIAN MULTICENTER STUDY.
Sobrado CW, Klajner S, Hora JAB, Mello A, Silva FMLD, Frugis MO, Sobrado LF
Arq Bras Cir Dig 2020;33(2):e1504. Epub 2020 Aug 24 doi: 10.1590/0102-672020190001e1504. PMID: 32844877Free PMC Article
Pathophysiology of late anorectal dysfunction following external beam radiotherapy for prostate cancer.
Petersen SE, Bregendahl S, Langschwager M, Laurberg S, Brock C, Drewes AM, Krogh K, Høyer M, Lundby L
Acta Oncol 2014 Oct;53(10):1398-404. Epub 2014 Jun 24 doi: 10.3109/0284186X.2014.926029. PMID: 24960583
High-resolution anoscopy: clinical features of anal intraepithelial neoplasia in HIV-positive men.
Richel O, Hallensleben ND, Kreuter A, van Noesel CJ, Prins JM, de Vries HJ
Dis Colon Rectum 2013 Nov;56(11):1237-42. doi: 10.1097/DCR.0b013e3182a53568. PMID: 24104998
Anal continence after rectocele repair.
Ayabaca SM, Zbar AP, Pescatori M
Dis Colon Rectum 2002 Jan;45(1):63-9. doi: 10.1007/s10350-004-6115-2. PMID: 11786766

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