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Scirrhous adenocarcinoma

MedGen UID:
2873
•Concept ID:
C0007135
•
Neoplastic Process
Synonyms: Adenocarcinoma, Scirrhous; Adenocarcinomas, Scirrhous; Carcinoma, Scirrhous; Carcinomas, Scirrhous; Scirrhous Adenocarcinoma; Scirrhous Adenocarcinomas; Scirrhous Carcinoma; Scirrhous Carcinomas
SNOMED CT: Scirrhous adenocarcinoma (4584002); Scirrhous carcinoma (4584002); Carcinoma with productive fibrosis (4584002)
 
Monarch Initiative: MONDO:0005953

Definition

An infiltrating adenocarcinoma characterized by the presence of desmoplastic stromal reaction. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVScirrhous adenocarcinoma

Professional guidelines

PubMed

The Genomic Signatures of Linitis Plastica Signal the Entrance into a New Era: Novel Approaches for Diagnosis and Treatment.
Christodoulidis G, Koumarelas KE, Kouliou MN, Samara M, Thodou E, Zacharoulis D
Int J Mol Sci 2023 Sep 28;24(19) doi: 10.3390/ijms241914680. PMID: 37834127Free PMC Article
Familial gastric and pancreatic cancers: Diagnosis and screening.
Raymond VM, Stoffel EM
Am Soc Clin Oncol Educ Book 2013 doi: 10.14694/EdBook_AM.2013.33.e44. PMID: 23714452
An analysis of the role of radiotherapy alone and in combination with chemotherapy and surgery in the management of advanced breast carcinoma.
Balawajder I, Antich PP, Boland J
Cancer 1983 Feb 15;51(4):574-80. doi: 10.1002/1097-0142(19830215)51:4<574::aid-cncr2820510403>3.0.co;2-b. PMID: 6295609

Recent clinical studies

Etiology

Neoadjuvant chemotherapy for gastric cancer in Japan: a standing position by comparing with adjuvant chemotherapy.
Yoshikawa T, Rino Y, Yukawa N, Oshima T, Tsuburaya A, Masuda M
Surg Today 2014 Jan;44(1):11-21. Epub 2013 Mar 19 doi: 10.1007/s00595-013-0529-1. PMID: 23508452
Mach bands in mammography.
Gordenne WH, Malchair FL
Radiology 1988 Oct;169(1):55-8. doi: 10.1148/radiology.169.1.2843941. PMID: 2843941
Aspiration of breast cysts.
Dohrmann PJ, Hughes ES, McDermott FT, Price AB
Aust N Z J Surg 1982 Dec;52(6):605-7. doi: 10.1111/j.1445-2197.1982.tb06123.x. PMID: 6299260
Pregnancy and breast cancer.
Hubay CA, Barry FM, Marr CC
Surg Clin North Am 1978 Aug;58(4):819-31. doi: 10.1016/s0039-6109(16)41594-x. PMID: 210528
Gastric exfoliative cytology.
Carney JA
Surg Clin North Am 1971 Aug;51(4):979-91. doi: 10.1016/s0039-6109(16)39494-4. PMID: 4329580

Diagnosis

Neoadjuvant chemotherapy for gastric cancer in Japan: a standing position by comparing with adjuvant chemotherapy.
Yoshikawa T, Rino Y, Yukawa N, Oshima T, Tsuburaya A, Masuda M
Surg Today 2014 Jan;44(1):11-21. Epub 2013 Mar 19 doi: 10.1007/s00595-013-0529-1. PMID: 23508452
Immunohistochemical pitfalls and the importance of glypican 3 and arginase in the diagnosis of scirrhous hepatocellular carcinoma.
Krings G, Ramachandran R, Jain D, Wu TT, Yeh MM, Torbenson M, Kakar S
Mod Pathol 2013 Jun;26(6):782-91. Epub 2013 Jan 25 doi: 10.1038/modpathol.2012.243. PMID: 23348905
Pregnancy and breast cancer.
Hubay CA, Barry FM, Marr CC
Surg Clin North Am 1978 Aug;58(4):819-31. doi: 10.1016/s0039-6109(16)41594-x. PMID: 210528
Ultrasound mammography.
Baum G
Radiology 1977 Jan;122(1):199-205. doi: 10.1148/122.1.199. PMID: 186842
RED-CELL APLASIA.
BOOTH JB
Br Med J 1965 Jan 16;1(5428):188-9. doi: 10.1136/bmj.1.5428.188-c. PMID: 14222608Free PMC Article

Therapy

Is FGFR2 a Suitable Target to Treat Scirrhous-Type Gastric Cancer?
Yasui W
Ann Surg Oncol 2019 Apr;26(4):926-927. Epub 2019 Jan 8 doi: 10.1245/s10434-018-07146-1. PMID: 30623340
Neoadjuvant chemotherapy for gastric cancer in Japan: a standing position by comparing with adjuvant chemotherapy.
Yoshikawa T, Rino Y, Yukawa N, Oshima T, Tsuburaya A, Masuda M
Surg Today 2014 Jan;44(1):11-21. Epub 2013 Mar 19 doi: 10.1007/s00595-013-0529-1. PMID: 23508452
Recent results of therapy for scirrhous gastric cancer.
Ikeguchi M, Miyake T, Matsunaga T, Yamamoto M, Fukumoto Y, Yamada Y, Fukuda K, Saito H, Tatebe S, Tsujitani S
Surg Today 2009;39(4):290-4. Epub 2009 Mar 25 doi: 10.1007/s00595-008-3860-1. PMID: 19319634
Tranilast and cisplatin as an experimental combination therapy for scirrhous gastric cancer.
Murahashi K, Yashiro M, Inoue T, Nishimura S, Matsuoka T, Sawada T, Sowa M, Hirakawa-Ys Chung K
Int J Oncol 1998 Dec;13(6):1235-40. doi: 10.3892/ijo.13.6.1235. PMID: 9824637
Aspiration of breast cysts.
Dohrmann PJ, Hughes ES, McDermott FT, Price AB
Aust N Z J Surg 1982 Dec;52(6):605-7. doi: 10.1111/j.1445-2197.1982.tb06123.x. PMID: 6299260

Prognosis

Neoadjuvant chemotherapy for gastric cancer in Japan: a standing position by comparing with adjuvant chemotherapy.
Yoshikawa T, Rino Y, Yukawa N, Oshima T, Tsuburaya A, Masuda M
Surg Today 2014 Jan;44(1):11-21. Epub 2013 Mar 19 doi: 10.1007/s00595-013-0529-1. PMID: 23508452
Immunohistochemical pitfalls and the importance of glypican 3 and arginase in the diagnosis of scirrhous hepatocellular carcinoma.
Krings G, Ramachandran R, Jain D, Wu TT, Yeh MM, Torbenson M, Kakar S
Mod Pathol 2013 Jun;26(6):782-91. Epub 2013 Jan 25 doi: 10.1038/modpathol.2012.243. PMID: 23348905
Clinicopathologic characteristics and long-term prognosis of scirrhous hepatocellular carcinoma.
Lee JH, Choi MS, Gwak GY, Lee JH, Koh KC, Paik SW, Yoo BC, Choi D, Park CK
Dig Dis Sci 2012 Jun;57(6):1698-707. Epub 2012 Feb 11 doi: 10.1007/s10620-012-2075-x. PMID: 22327241
Differences between scirrhous and non-scirrhous human gastric carcinomas from the aspect of proMMP-2 activation regulated by TIMP-3.
Yokoyama T, Nakamura H, Otani Y, Kubota T, Fujimoto N, Seiki M, Kitajima M, Okada Y
Clin Exp Metastasis 2004;21(3):223-33. doi: 10.1023/b:clin.0000037704.72028.72. PMID: 15387372
Pregnancy and breast cancer.
Hubay CA, Barry FM, Marr CC
Surg Clin North Am 1978 Aug;58(4):819-31. doi: 10.1016/s0039-6109(16)41594-x. PMID: 210528

Clinical prediction guides

Immunohistochemical pitfalls and the importance of glypican 3 and arginase in the diagnosis of scirrhous hepatocellular carcinoma.
Krings G, Ramachandran R, Jain D, Wu TT, Yeh MM, Torbenson M, Kakar S
Mod Pathol 2013 Jun;26(6):782-91. Epub 2013 Jan 25 doi: 10.1038/modpathol.2012.243. PMID: 23348905
Clinicopathologic characteristics and long-term prognosis of scirrhous hepatocellular carcinoma.
Lee JH, Choi MS, Gwak GY, Lee JH, Koh KC, Paik SW, Yoo BC, Choi D, Park CK
Dig Dis Sci 2012 Jun;57(6):1698-707. Epub 2012 Feb 11 doi: 10.1007/s10620-012-2075-x. PMID: 22327241
Mach bands in mammography.
Gordenne WH, Malchair FL
Radiology 1988 Oct;169(1):55-8. doi: 10.1148/radiology.169.1.2843941. PMID: 2843941
Vitamin C and cancer: an overview.
Cameron E
Int J Vitam Nutr Res Suppl 1982;23:115-27. PMID: 6180998
Pregnancy and breast cancer.
Hubay CA, Barry FM, Marr CC
Surg Clin North Am 1978 Aug;58(4):819-31. doi: 10.1016/s0039-6109(16)41594-x. PMID: 210528

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