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Delayed Graft Function

MedGen UID:
290305
•Concept ID:
C1566590
•
Pathologic Function
Synonym: Graft Function, Delayed

Definition

The need for dialysis within a week of kidney transplant. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDelayed Graft Function

Professional guidelines

PubMed

Mechanisms and management of drug-induced hyperkalemia in kidney transplant patients.
Rizk JG, Lazo JG Jr, Quan D, Gabardi S, Rizk Y, Streja E, Kovesdy CP, Kalantar-Zadeh K
Rev Endocr Metab Disord 2021 Dec;22(4):1157-1170. Epub 2021 Jul 22 doi: 10.1007/s11154-021-09677-7. PMID: 34292479
Delayed graft function and its management in children.
Grenda R
Pediatr Nephrol 2017 Jul;32(7):1157-1167. Epub 2016 Oct 24 doi: 10.1007/s00467-016-3528-9. PMID: 27778091
Prediction, prevention, and management of delayed graft function: where are we now?
Nashan B, Abbud-Filho M, Citterio F
Clin Transplant 2016 Oct;30(10):1198-1208. Epub 2016 Sep 12 doi: 10.1111/ctr.12832. PMID: 27543840

Recent clinical studies

Etiology

Hypothermia or Machine Perfusion in Kidney Donors.
Malinoski D, Saunders C, Swain S, Groat T, Wood PR, Reese J, Nelson R, Prinz J, Kishish K, Van De Walker C, Geraghty PJ, Broglio K, Niemann CU
N Engl J Med 2023 Feb 2;388(5):418-426. doi: 10.1056/NEJMoa2118265. PMID: 36724328
Delayed graft function: current status and future directions.
Swanson KJ, Bhattarai M, Parajuli S
Curr Opin Organ Transplant 2023 Feb 1;28(1):1-7. Epub 2022 Nov 7 doi: 10.1097/MOT.0000000000001034. PMID: 36579681
Delayed graft function in kidney transplantation.
Bahl D, Haddad Z, Datoo A, Qazi YA
Curr Opin Organ Transplant 2019 Feb;24(1):82-86. doi: 10.1097/MOT.0000000000000604. PMID: 30540574
Delayed Graft Function: The AKI of Kidney Transplantation.
Mannon RB
Nephron 2018;140(2):94-98. Epub 2018 Jul 13 doi: 10.1159/000491558. PMID: 30007955Free PMC Article
Delayed graft function and its management in children.
Grenda R
Pediatr Nephrol 2017 Jul;32(7):1157-1167. Epub 2016 Oct 24 doi: 10.1007/s00467-016-3528-9. PMID: 27778091

Diagnosis

Update on current and potential application of extracellular vesicles in kidney transplantation.
Abinti M, Favi E, Alfieri CM, Zanoni F, Armelloni S, Ferraresso M, Cantaluppi V, Castellano G
Am J Transplant 2023 Nov;23(11):1673-1693. Epub 2023 Jul 28 doi: 10.1016/j.ajt.2023.07.010. PMID: 37517555
Machine perfusion in kidney transplantation.
Kataria A, Magoon S, Makkar B, Gundroo A
Curr Opin Organ Transplant 2019 Aug;24(4):378-384. doi: 10.1097/MOT.0000000000000675. PMID: 31205093
Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment-A consensus report from the Pulmonary Council of the ISHLT.
Verleden GM, Glanville AR, Lease ED, Fisher AJ, Calabrese F, Corris PA, Ensor CR, Gottlieb J, Hachem RR, Lama V, Martinu T, Neil DAH, Singer LG, Snell G, Vos R
J Heart Lung Transplant 2019 May;38(5):493-503. Epub 2019 Apr 3 doi: 10.1016/j.healun.2019.03.009. PMID: 30962148
Kidney transplantation for HIV-positive patients.
Sawinski D
Transplant Rev (Orlando) 2017 Jan;31(1):42-46. Epub 2016 Oct 11 doi: 10.1016/j.trre.2016.10.003. PMID: 27776929
Prediction, prevention, and management of delayed graft function: where are we now?
Nashan B, Abbud-Filho M, Citterio F
Clin Transplant 2016 Oct;30(10):1198-1208. Epub 2016 Sep 12 doi: 10.1111/ctr.12832. PMID: 27543840

Therapy

Hypothermia or Machine Perfusion in Kidney Donors.
Malinoski D, Saunders C, Swain S, Groat T, Wood PR, Reese J, Nelson R, Prinz J, Kishish K, Van De Walker C, Geraghty PJ, Broglio K, Niemann CU
N Engl J Med 2023 Feb 2;388(5):418-426. doi: 10.1056/NEJMoa2118265. PMID: 36724328
Delayed graft function: current status and future directions.
Swanson KJ, Bhattarai M, Parajuli S
Curr Opin Organ Transplant 2023 Feb 1;28(1):1-7. Epub 2022 Nov 7 doi: 10.1097/MOT.0000000000001034. PMID: 36579681
Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment-A consensus report from the Pulmonary Council of the ISHLT.
Verleden GM, Glanville AR, Lease ED, Fisher AJ, Calabrese F, Corris PA, Ensor CR, Gottlieb J, Hachem RR, Lama V, Martinu T, Neil DAH, Singer LG, Snell G, Vos R
J Heart Lung Transplant 2019 May;38(5):493-503. Epub 2019 Apr 3 doi: 10.1016/j.healun.2019.03.009. PMID: 30962148
Machine perfusion preservation versus static cold storage for deceased donor kidney transplantation.
Tingle SJ, Figueiredo RS, Moir JA, Goodfellow M, Talbot D, Wilson CH
Cochrane Database Syst Rev 2019 Mar 15;3(3):CD011671. doi: 10.1002/14651858.CD011671.pub2. PMID: 30875082Free PMC Article
Delayed graft function in kidney transplantation.
Bahl D, Haddad Z, Datoo A, Qazi YA
Curr Opin Organ Transplant 2019 Feb;24(1):82-86. doi: 10.1097/MOT.0000000000000604. PMID: 30540574

Prognosis

Editorial: Transplantation of Marginal Organs-Immunological Aspects and Therapeutic Perspectives.
Süsal C, Mueller TF, Legendre C, Schemmer P
Front Immunol 2020;11:612576. Epub 2020 Oct 29 doi: 10.3389/fimmu.2020.612576. PMID: 33193459Free PMC Article
Five compelling UTI questions after kidney transplant.
Aydın S, Patil A, Desai M, Simforoosh N
World J Urol 2020 Nov;38(11):2733-2742. Epub 2020 Apr 7 doi: 10.1007/s00345-020-03173-4. PMID: 32266510
Delayed Graft Function Phenotypes and 12-Month Kidney Transplant Outcomes.
Hall IE, Reese PP, Doshi MD, Weng FL, Schröppel B, Asch WS, Ficek J, Thiessen-Philbrook H, Parikh CR
Transplantation 2017 Aug;101(8):1913-1923. doi: 10.1097/TP.0000000000001409. PMID: 27495761Free PMC Article
Delayed Graft Function in Living-Donor Kidney Transplant: A Middle Eastern Perspective.
Al Otaibi T, Ahmadpoor P, Allawi AA, Habhab WT, Khatami MR, Nafar M, Glotz D
Exp Clin Transplant 2016 Feb;14(1):1-11. PMID: 26862818
Association between delayed graft function and allograft and patient survival: a systematic review and meta-analysis.
Yarlagadda SG, Coca SG, Formica RN Jr, Poggio ED, Parikh CR
Nephrol Dial Transplant 2009 Mar;24(3):1039-47. Epub 2008 Dec 22 doi: 10.1093/ndt/gfn667. PMID: 19103734

Clinical prediction guides

Delayed graft function: current status and future directions.
Swanson KJ, Bhattarai M, Parajuli S
Curr Opin Organ Transplant 2023 Feb 1;28(1):1-7. Epub 2022 Nov 7 doi: 10.1097/MOT.0000000000001034. PMID: 36579681
Predictors of Delayed Graft Function in Renal Transplantation.
Kernig K, Albrecht V, Dräger DL, Führer A, Mitzner S, Kundt G, Hakenberg OW
Urol Int 2022;106(5):512-517. Epub 2021 Dec 16 doi: 10.1159/000520055. PMID: 34915519Free PMC Article
Delayed Graft Function: The AKI of Kidney Transplantation.
Mannon RB
Nephron 2018;140(2):94-98. Epub 2018 Jul 13 doi: 10.1159/000491558. PMID: 30007955Free PMC Article
Delayed graft function and its management in children.
Grenda R
Pediatr Nephrol 2017 Jul;32(7):1157-1167. Epub 2016 Oct 24 doi: 10.1007/s00467-016-3528-9. PMID: 27778091
Prediction, prevention, and management of delayed graft function: where are we now?
Nashan B, Abbud-Filho M, Citterio F
Clin Transplant 2016 Oct;30(10):1198-1208. Epub 2016 Sep 12 doi: 10.1111/ctr.12832. PMID: 27543840

Recent systematic reviews

Association Between Pretransplant Dialysis Modality and Kidney Transplant Outcomes: A Systematic Review and Meta-analysis.
Ngamvichchukorn T, Ruengorn C, Noppakun K, Thavorn K, Hutton B, Sood MM, Knoll GA, Nochaiwong S
JAMA Netw Open 2022 Oct 3;5(10):e2237580. doi: 10.1001/jamanetworkopen.2022.37580. PMID: 36264575Free PMC Article
Surgical Approaches and Outcomes in Living Donor Nephrectomy: A Systematic Review and Meta-analysis.
Dagnæs-Hansen J, Kristensen GH, Stroomberg HV, Sørensen SS, Røder MA
Eur Urol Focus 2022 Nov;8(6):1795-1801. Epub 2022 Apr 22 doi: 10.1016/j.euf.2022.03.021. PMID: 35469780
Machine perfusion preservation versus static cold storage for deceased donor kidney transplantation.
Tingle SJ, Figueiredo RS, Moir JA, Goodfellow M, Talbot D, Wilson CH
Cochrane Database Syst Rev 2019 Mar 15;3(3):CD011671. doi: 10.1002/14651858.CD011671.pub2. PMID: 30875082Free PMC Article
Dual kidney transplant techniques: A systematic review.
Cocco A, Shahrestani S, Cocco N, Hameed A, Yuen L, Ryan B, Hawthorne W, Lam V, Pleass H
Clin Transplant 2017 Aug;31(8) Epub 2017 Jun 23 doi: 10.1111/ctr.13016. PMID: 28544075
Recipient obesity and outcomes after kidney transplantation: a systematic review and meta-analysis.
Hill CJ, Courtney AE, Cardwell CR, Maxwell AP, Lucarelli G, Veroux M, Furriel F, Cannon RM, Hoogeveen EK, Doshi M, McCaughan JA
Nephrol Dial Transplant 2015 Aug;30(8):1403-11. Epub 2015 Jun 4 doi: 10.1093/ndt/gfv214. PMID: 26044837

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