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Oral Cavity Mucositis or Stomatitis by Functional or Symptomatic Classification, CTCAE

MedGen UID:
291668
•Concept ID:
C1556436
•
Finding

Professional guidelines

PubMed

Prevention and treatment of peri-implant diseases-The EFP S3 level clinical practice guideline.
Herrera D, Berglundh T, Schwarz F, Chapple I, Jepsen S, Sculean A, Kebschull M, Papapanou PN, Tonetti MS, Sanz M; EFP workshop participants and methodological consultant
J Clin Periodontol 2023 Jun;50 Suppl 26:4-76. Epub 2023 Jun 4 doi: 10.1111/jcpe.13823. PMID: 37271498
Clinical Practice Guideline: Nosebleed (Epistaxis).
Tunkel DE, Anne S, Payne SC, Ishman SL, Rosenfeld RM, Abramson PJ, Alikhaani JD, Benoit MM, Bercovitz RS, Brown MD, Chernobilsky B, Feldstein DA, Hackell JM, Holbrook EH, Holdsworth SM, Lin KW, Lind MM, Poetker DM, Riley CA, Schneider JS, Seidman MD, Vadlamudi V, Valdez TA, Nnacheta LC, Monjur TM
Otolaryngol Head Neck Surg 2020 Jan;162(1_suppl):S1-S38. doi: 10.1177/0194599819890327. PMID: 31910111
Clinical Practice Guideline: Tonsillectomy in Children (Update)-Executive Summary.
Mitchell RB, Archer SM, Ishman SL, Rosenfeld RM, Coles S, Finestone SA, Friedman NR, Giordano T, Hildrew DM, Kim TW, Lloyd RM, Parikh SR, Shulman ST, Walner DL, Walsh SA, Nnacheta LC
Otolaryngol Head Neck Surg 2019 Feb;160(2):187-205. doi: 10.1177/0194599818807917. PMID: 30921525

Recent clinical studies

Etiology

The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies.
Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST
CA Cancer J Clin 2022 Jan;72(1):57-77. Epub 2021 Oct 29 doi: 10.3322/caac.21704. PMID: 34714553
HPV-Related Papillary Lesions of the Oral Mucosa: A Review.
Betz SJ
Head Neck Pathol 2019 Mar;13(1):80-90. Epub 2019 Jan 29 doi: 10.1007/s12105-019-01003-7. PMID: 30693456Free PMC Article
Premalignant and malignant oral mucosal lesions: Clinical and pathological findings.
Maymone MBC, Greer RO, Kesecker J, Sahitya PC, Burdine LK, Cheng AD, Maymone AC, Vashi NA
J Am Acad Dermatol 2019 Jul;81(1):59-71. Epub 2018 Nov 14 doi: 10.1016/j.jaad.2018.09.060. PMID: 30447325
Benign oral mucosal lesions: Clinical and pathological findings.
Maymone MBC, Greer RO, Burdine LK, Dao-Cheng A, Venkatesh S, Sahitya PC, Maymone AC, Kesecker J, Vashi NA
J Am Acad Dermatol 2019 Jul;81(1):43-56. Epub 2018 Nov 14 doi: 10.1016/j.jaad.2018.09.061. PMID: 30447312
Oral pathology in inflammatory bowel disease.
Muhvić-Urek M, Tomac-Stojmenović M, Mijandrušić-Sinčić B
World J Gastroenterol 2016 Jul 7;22(25):5655-67. doi: 10.3748/wjg.v22.i25.5655. PMID: 27433081Free PMC Article

Diagnosis

Mucous membrane pemphigoid.
Du G, Patzelt S, van Beek N, Schmidt E
Autoimmun Rev 2022 Apr;21(4):103036. Epub 2022 Jan 4 doi: 10.1016/j.autrev.2022.103036. PMID: 34995762
The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies.
Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST
CA Cancer J Clin 2022 Jan;72(1):57-77. Epub 2021 Oct 29 doi: 10.3322/caac.21704. PMID: 34714553
Ulcerated Lesions of the Oral Mucosa: Clinical and Histologic Review.
Fitzpatrick SG, Cohen DM, Clark AN
Head Neck Pathol 2019 Mar;13(1):91-102. Epub 2019 Mar 7 doi: 10.1007/s12105-018-0981-8. PMID: 30701449Free PMC Article
HPV-Related Papillary Lesions of the Oral Mucosa: A Review.
Betz SJ
Head Neck Pathol 2019 Mar;13(1):80-90. Epub 2019 Jan 29 doi: 10.1007/s12105-019-01003-7. PMID: 30693456Free PMC Article
Premalignant and malignant oral mucosal lesions: Clinical and pathological findings.
Maymone MBC, Greer RO, Kesecker J, Sahitya PC, Burdine LK, Cheng AD, Maymone AC, Vashi NA
J Am Acad Dermatol 2019 Jul;81(1):59-71. Epub 2018 Nov 14 doi: 10.1016/j.jaad.2018.09.060. PMID: 30447325

Therapy

The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies.
Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST
CA Cancer J Clin 2022 Jan;72(1):57-77. Epub 2021 Oct 29 doi: 10.3322/caac.21704. PMID: 34714553
Managing Oral Mucositis in Patients With Cancer.
Bolton L
Wounds 2021 May;33(5):136-138. PMID: 34370681
Early side effects of radiation treatment for head and neck cancer.
Brook I
Cancer Radiother 2021 Jul;25(5):507-513. Epub 2021 Mar 5 doi: 10.1016/j.canrad.2021.02.001. PMID: 33685809
Chemotherapy-induced oral mucositis is associated with detrimental bacterial dysbiosis.
Hong BY, Sobue T, Choquette L, Dupuy AK, Thompson A, Burleson JA, Salner AL, Schauer PK, Joshi P, Fox E, Shin DG, Weinstock GM, Strausbaugh LD, Dongari-Bagtzoglou A, Peterson DE, Diaz PI
Microbiome 2019 Apr 25;7(1):66. doi: 10.1186/s40168-019-0679-5. PMID: 31018870Free PMC Article
Oral pathology in inflammatory bowel disease.
Muhvić-Urek M, Tomac-Stojmenović M, Mijandrušić-Sinčić B
World J Gastroenterol 2016 Jul 7;22(25):5655-67. doi: 10.3748/wjg.v22.i25.5655. PMID: 27433081Free PMC Article

Prognosis

The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies.
Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST
CA Cancer J Clin 2022 Jan;72(1):57-77. Epub 2021 Oct 29 doi: 10.3322/caac.21704. PMID: 34714553
EBV-positive mucocutaneous ulceration.
Jivraj A, Evans K, Reza M, Qureshi A, Srinivasan D
Ann R Coll Surg Engl 2021 Nov;103(10):e335-e337. Epub 2021 Aug 26 doi: 10.1308/rcsann.2021.0051. PMID: 34436949Free PMC Article
Premalignant and malignant oral mucosal lesions: Clinical and pathological findings.
Maymone MBC, Greer RO, Kesecker J, Sahitya PC, Burdine LK, Cheng AD, Maymone AC, Vashi NA
J Am Acad Dermatol 2019 Jul;81(1):59-71. Epub 2018 Nov 14 doi: 10.1016/j.jaad.2018.09.060. PMID: 30447325
Oral varix: a review.
Lazos JP, Piemonte ED, Panico RL
Gerodontology 2015 Jun;32(2):82-9. Epub 2013 Sep 1 doi: 10.1111/ger.12074. PMID: 23992044
Palatal ulceration.
Sardana K, Bansal S
Clin Dermatol 2014 Nov-Dec;32(6):827-38. Epub 2014 Mar 1 doi: 10.1016/j.clindermatol.2014.02.023. PMID: 25441477

Clinical prediction guides

The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies.
Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST
CA Cancer J Clin 2022 Jan;72(1):57-77. Epub 2021 Oct 29 doi: 10.3322/caac.21704. PMID: 34714553
Oral pigmented lesions in syndromic individuals: A systematic review.
Ferreira LDS, Calderipe CB, Maass JB, Carrard VC, Martins MD, Abreu LG, Schuch LF, Uchoa Vasconcelos AC
Oral Dis 2022 Apr;28(3):531-540. Epub 2021 Jan 16 doi: 10.1111/odi.13769. PMID: 33394507
Oral mucosal changes induced by anticancer targeted therapies and immune checkpoint inhibitors.
Vigarios E, Epstein JB, Sibaud V
Support Care Cancer 2017 May;25(5):1713-1739. Epub 2017 Feb 22 doi: 10.1007/s00520-017-3629-4. PMID: 28224235
The aging mouth: differentiating normal aging from disease.
Lamster IB, Asadourian L, Del Carmen T, Friedman PK
Periodontol 2000 2016 Oct;72(1):96-107. doi: 10.1111/prd.12131. PMID: 27501493
Saliva and wound healing.
Brand HS, Veerman EC
Chin J Dent Res 2013;16(1):7-12. PMID: 23878824

Recent systematic reviews

Effects of Electronic Cigarettes on Oral Cavity: A Systematic Review.
Ralho A, Coelho A, Ribeiro M, Paula A, Amaro I, Sousa J, Marto C, Ferreira M, Carrilho E
J Evid Based Dent Pract 2019 Dec;19(4):101318. Epub 2019 Apr 8 doi: 10.1016/j.jebdp.2019.04.002. PMID: 31843181
Effects of soft tissue augmentation procedures on peri-implant health or disease: A systematic review and meta-analysis.
Thoma DS, Naenni N, Figuero E, Hämmerle CHF, Schwarz F, Jung RE, Sanz-Sánchez I
Clin Oral Implants Res 2018 Mar;29 Suppl 15:32-49. doi: 10.1111/clr.13114. PMID: 29498129
Oral manifestations of Diabetes Mellitus. A systematic review.
Mauri-Obradors E, Estrugo-Devesa A, Jané-Salas E, Viñas M, López-López J
Med Oral Patol Oral Cir Bucal 2017 Sep 1;22(5):e586-e594. doi: 10.4317/medoral.21655. PMID: 28809366Free PMC Article
Prevalences of peri-implantitis and peri-implant mucositis: systematic review and meta-analysis.
Lee CT, Huang YW, Zhu L, Weltman R
J Dent 2017 Jul;62:1-12. Epub 2017 May 3 doi: 10.1016/j.jdent.2017.04.011. PMID: 28478213
Treatment of xerostomia and hyposalivation in the elderly: A systematic review.
Gil-Montoya JA, Silvestre FJ, Barrios R, Silvestre-Rangil J
Med Oral Patol Oral Cir Bucal 2016 May 1;21(3):e355-66. doi: 10.4317/medoral.20969. PMID: 27031061Free PMC Article

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