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Grade 4 Stoma GI Stricture or Stenosis, CTCAE

MedGen UID:
293208
•Concept ID:
C1559444
•
Finding
Synonym: CTCAE Grade 4 Stoma GI stricture/stenosis (including anastomotic)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 4 Stoma GI Stricture or Stenosis, CTCAE

Professional guidelines

PubMed

Long-term urological complications after conservative local treatment (surgery and brachytherapy) in children with bladder-prostate rhabdomyosarcoma: A single-team experience.
Akkary R, Guérin F, Chargari C, Jochault L, Audry G, Pio L, Minard-Colin V, Haie-Meder C, Martelli H
Pediatr Blood Cancer 2022 Aug;69(8):e29532. Epub 2022 Jan 6 doi: 10.1002/pbc.29532. PMID: 35739611

Recent clinical studies

Etiology

Vaginal stenosis in women with cervical or endometrial cancer after pelvic radiotherapy: a cross-sectional study of vaginal measurements, risk for sexual dysfunction and quality of life.
de Morais Siqueira T, Derchain S, Juliato CRT, Pinto E Silva MP, Machado HC, Brito LGO
Int Urogynecol J 2022 Mar;33(3):637-649. Epub 2021 Apr 23 doi: 10.1007/s00192-021-04798-8. PMID: 33891152
Topical estrogen, testosterone, and vaginal dilator in the prevention of vaginal stenosis after radiotherapy in women with cervical cancer: a randomized clinical trial.
Martins J, Vaz AF, Grion RC, Costa-Paiva L, Baccaro LF
BMC Cancer 2021 Jun 10;21(1):682. doi: 10.1186/s12885-021-08274-w. PMID: 34112100Free PMC Article
Vaginal dose-surface maps in cervical cancer brachytherapy: Methodology and preliminary results on correlation with morbidity.
Serban M, de Leeuw AAC, Tanderup K, Jürgenliemk-Schulz IM
Brachytherapy 2021 May-Jun;20(3):565-575. Epub 2021 Mar 17 doi: 10.1016/j.brachy.2021.02.004. PMID: 33741274
Ureteral stenosis after 3D MRI-based brachytherapy for cervical cancer - Have we identified all the risk factors?
Rodríguez-López JL, Ling DC, Keller A, Kim H, Mojica-Márquez AE, Glaser SM, Beriwal S
Radiother Oncol 2021 Feb;155:86-92. Epub 2020 Oct 14 doi: 10.1016/j.radonc.2020.10.010. PMID: 33065181
Brachytherapy for vaginal intraepithelial neoplasia.
Zolciak-Siwinska A, Gruszczynska E, Jonska-Gmyrek J, Kulik A, Michalski W
Eur J Obstet Gynecol Reprod Biol 2015 Nov;194:73-7. Epub 2015 Aug 22 doi: 10.1016/j.ejogrb.2015.08.018. PMID: 26334358

Diagnosis

Topical estrogen, testosterone, and vaginal dilator in the prevention of vaginal stenosis after radiotherapy in women with cervical cancer: a randomized clinical trial.
Martins J, Vaz AF, Grion RC, Costa-Paiva L, Baccaro LF
BMC Cancer 2021 Jun 10;21(1):682. doi: 10.1186/s12885-021-08274-w. PMID: 34112100Free PMC Article
Central Airway Toxicity After High Dose Radiation: A Combined Analysis of Prospective Clinical Trials for Non-Small Cell Lung Cancer.
Wang W, Matuszak MM, Hu C, Huang KC, Chen E, Arenberg D, Curtis JL, Jolly S, Jin JY, Machtay M, Ten Haken RK, Kong FS
Int J Radiat Oncol Biol Phys 2020 Nov 1;108(3):587-596. Epub 2020 May 26 doi: 10.1016/j.ijrobp.2020.05.026. PMID: 32470501Free PMC Article
DW-MRI predictive factors for radiation-induced vaginal stenosis in patients with cervical cancer.
Miccò M, Campitelli M, Sbarra M, Carra N, Barone R, Gui B, Gambacorta MA, Valentini V, Manfredi R
Clin Radiol 2020 Mar;75(3):216-223. Epub 2019 Dec 2 doi: 10.1016/j.crad.2019.10.021. PMID: 31806362

Therapy

Late toxicity within a Phase III clinical trial of IG-IMRT in cervix cancer (PARCER): Reanalysis with time weighted adverse event reporting (MOSES).
Supriya C, Nilesh R, Mayuri C, Sadhana K, Reena E, Tapas D, Lavanya G, Prachi M, Amita M, Shylasree TS, Shyam S, Sudeep G
Radiother Oncol 2022 Dec;177:16-20. Epub 2022 Oct 18 doi: 10.1016/j.radonc.2022.10.013. PMID: 36270474
Topical estrogen, testosterone, and vaginal dilator in the prevention of vaginal stenosis after radiotherapy in women with cervical cancer: a randomized clinical trial.
Martins J, Vaz AF, Grion RC, Costa-Paiva L, Baccaro LF
BMC Cancer 2021 Jun 10;21(1):682. doi: 10.1186/s12885-021-08274-w. PMID: 34112100Free PMC Article
Ureteral stenosis after 3D MRI-based brachytherapy for cervical cancer - Have we identified all the risk factors?
Rodríguez-López JL, Ling DC, Keller A, Kim H, Mojica-Márquez AE, Glaser SM, Beriwal S
Radiother Oncol 2021 Feb;155:86-92. Epub 2020 Oct 14 doi: 10.1016/j.radonc.2020.10.010. PMID: 33065181
Central Airway Toxicity After High Dose Radiation: A Combined Analysis of Prospective Clinical Trials for Non-Small Cell Lung Cancer.
Wang W, Matuszak MM, Hu C, Huang KC, Chen E, Arenberg D, Curtis JL, Jolly S, Jin JY, Machtay M, Ten Haken RK, Kong FS
Int J Radiat Oncol Biol Phys 2020 Nov 1;108(3):587-596. Epub 2020 May 26 doi: 10.1016/j.ijrobp.2020.05.026. PMID: 32470501Free PMC Article
Brachytherapy for vaginal intraepithelial neoplasia.
Zolciak-Siwinska A, Gruszczynska E, Jonska-Gmyrek J, Kulik A, Michalski W
Eur J Obstet Gynecol Reprod Biol 2015 Nov;194:73-7. Epub 2015 Aug 22 doi: 10.1016/j.ejogrb.2015.08.018. PMID: 26334358

Prognosis

Topical estrogen, testosterone, and vaginal dilator in the prevention of vaginal stenosis after radiotherapy in women with cervical cancer: a randomized clinical trial.
Martins J, Vaz AF, Grion RC, Costa-Paiva L, Baccaro LF
BMC Cancer 2021 Jun 10;21(1):682. doi: 10.1186/s12885-021-08274-w. PMID: 34112100Free PMC Article
Vaginal dose-surface maps in cervical cancer brachytherapy: Methodology and preliminary results on correlation with morbidity.
Serban M, de Leeuw AAC, Tanderup K, Jürgenliemk-Schulz IM
Brachytherapy 2021 May-Jun;20(3):565-575. Epub 2021 Mar 17 doi: 10.1016/j.brachy.2021.02.004. PMID: 33741274
Ureteral stenosis after 3D MRI-based brachytherapy for cervical cancer - Have we identified all the risk factors?
Rodríguez-López JL, Ling DC, Keller A, Kim H, Mojica-Márquez AE, Glaser SM, Beriwal S
Radiother Oncol 2021 Feb;155:86-92. Epub 2020 Oct 14 doi: 10.1016/j.radonc.2020.10.010. PMID: 33065181
DW-MRI predictive factors for radiation-induced vaginal stenosis in patients with cervical cancer.
Miccò M, Campitelli M, Sbarra M, Carra N, Barone R, Gui B, Gambacorta MA, Valentini V, Manfredi R
Clin Radiol 2020 Mar;75(3):216-223. Epub 2019 Dec 2 doi: 10.1016/j.crad.2019.10.021. PMID: 31806362
Preoperative intensity modulated radiation therapy for retroperitoneal sarcoma.
El-Bared N, Taussky D, Mehiri S, Patocskai E, Roberge D, Donath D
Technol Cancer Res Treat 2014 Jun;13(3):211-6. Epub 2013 Aug 2 doi: 10.7785/tcrt.2012.500371. PMID: 23919397Free PMC Article

Clinical prediction guides

Late toxicity within a Phase III clinical trial of IG-IMRT in cervix cancer (PARCER): Reanalysis with time weighted adverse event reporting (MOSES).
Supriya C, Nilesh R, Mayuri C, Sadhana K, Reena E, Tapas D, Lavanya G, Prachi M, Amita M, Shylasree TS, Shyam S, Sudeep G
Radiother Oncol 2022 Dec;177:16-20. Epub 2022 Oct 18 doi: 10.1016/j.radonc.2022.10.013. PMID: 36270474
Vaginal dose-surface maps in cervical cancer brachytherapy: Methodology and preliminary results on correlation with morbidity.
Serban M, de Leeuw AAC, Tanderup K, Jürgenliemk-Schulz IM
Brachytherapy 2021 May-Jun;20(3):565-575. Epub 2021 Mar 17 doi: 10.1016/j.brachy.2021.02.004. PMID: 33741274
Ureteral stenosis after 3D MRI-based brachytherapy for cervical cancer - Have we identified all the risk factors?
Rodríguez-López JL, Ling DC, Keller A, Kim H, Mojica-Márquez AE, Glaser SM, Beriwal S
Radiother Oncol 2021 Feb;155:86-92. Epub 2020 Oct 14 doi: 10.1016/j.radonc.2020.10.010. PMID: 33065181
Brachytherapy for vaginal intraepithelial neoplasia.
Zolciak-Siwinska A, Gruszczynska E, Jonska-Gmyrek J, Kulik A, Michalski W
Eur J Obstet Gynecol Reprod Biol 2015 Nov;194:73-7. Epub 2015 Aug 22 doi: 10.1016/j.ejogrb.2015.08.018. PMID: 26334358
Preoperative intensity modulated radiation therapy for retroperitoneal sarcoma.
El-Bared N, Taussky D, Mehiri S, Patocskai E, Roberge D, Donath D
Technol Cancer Res Treat 2014 Jun;13(3):211-6. Epub 2013 Aug 2 doi: 10.7785/tcrt.2012.500371. PMID: 23919397Free PMC Article

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