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Taste Alteration, CTCAE

MedGen UID:
293212
•Concept ID:
C1559452
•
Finding

Professional guidelines

PubMed

Taste disorders following cancer treatment: report of a case series.
Epstein JB, de Andrade E Silva SM, Epstein GL, Leal JHS, Barasch A, Smutzer G
Support Care Cancer 2019 Dec;27(12):4587-4595. Epub 2019 Mar 29 doi: 10.1007/s00520-019-04758-5. PMID: 30927113

Recent clinical studies

Etiology

Taste alterations during neo/adjuvant chemotherapy and subsequent follow-up in breast cancer patients: a prospective single-center clinical study.
Pedersini R, Zamparini M, Bosio S, di Mauro P, Turla A, Monteverdi S, Zanini A, Amoroso V, Vassalli L, Cosentini D, Grisanti S, Simoncini EL, Berruti A
Support Care Cancer 2022 Aug;30(8):6955-6961. Epub 2022 May 11 doi: 10.1007/s00520-022-07091-6. PMID: 35538327
Multicenter, prospective, observational study of chemotherapy-induced dysgeusia in gastrointestinal cancer.
Ito K, Yuki S, Nakatsumi H, Kawamoto Y, Harada K, Nakano S, Saito R, Ando T, Sawada K, Yagisawa M, Ishiguro A, Dazai M, Iwanaga I, Hatanaka K, Sato A, Matsumoto R, Shindo Y, Tateyama M, Muranaka T, Katagiri M, Yokota I, Sakata Y, Sakamoto N, Komatsu Y
Support Care Cancer 2022 Jun;30(6):5351-5359. Epub 2022 Mar 15 doi: 10.1007/s00520-022-06936-4. PMID: 35292848Free PMC Article
Risk factors for dysgeusia during chemotherapy for solid tumors: a retrospective cross-sectional study.
Malta CEN, de Lima Martins JO, Carlos ACAM, Freitas MO, Magalhães IA, de Vasconcelos HCA, de Lima Silva-Fernandes IJ, de Barros Silva PG
Support Care Cancer 2022 Jan;30(1):313-325. Epub 2021 Jul 20 doi: 10.1007/s00520-021-06219-4. PMID: 34283319
Taste disorders following cancer treatment: report of a case series.
Epstein JB, de Andrade E Silva SM, Epstein GL, Leal JHS, Barasch A, Smutzer G
Support Care Cancer 2019 Dec;27(12):4587-4595. Epub 2019 Mar 29 doi: 10.1007/s00520-019-04758-5. PMID: 30927113
Radiotherapy for cutaneous head and neck cancer and parotid tumours: a prospective investigation of treatment-related acute swallowing and toxicity patterns.
Moroney LB, Helios J, Ward EC, Crombie J, Burns CL, Yeo SQ, Pelecanos A, Spurgin AL, Blake C, Kenny L, Chua B, Hughes BGM
Support Care Cancer 2019 Feb;27(2):573-581. Epub 2018 Jul 17 doi: 10.1007/s00520-018-4352-5. PMID: 30019149

Diagnosis

Occurrence of Dysgeusia in Patients Being Treated for Cancer.
Di Meglio J, Dinu M, Doni L, Rossi G, Giorgione R, Colombini B, Antonuzzo L, Sofi F
Nutr Cancer 2022;74(8):2868-2874. Epub 2022 Feb 23 doi: 10.1080/01635581.2022.2042569. PMID: 35196919
Oral examination findings, taste and smell testing during and following head and neck cancer therapy.
Epstein JB, Villines D, Epstein GL, Smutzer G
Support Care Cancer 2020 Sep;28(9):4305-4311. Epub 2020 Jan 7 doi: 10.1007/s00520-019-05232-y. PMID: 31912362
Self-evaluation of duration of adjuvant chemotherapy side effects in breast cancer patients: A prospective study.
Galizia D, Milani A, Geuna E, Martinello R, Cagnazzo C, Foresto M, Longo V, Berchialla P, Solinas G, Calori A, Grasso B, Volpone C, Bertola G, Parola G, Tealdi G, Giuliano PL, Ballari AM, Aglietta M, Montemurro F
Cancer Med 2018 Sep;7(9):4339-4344. Epub 2018 Jul 20 doi: 10.1002/cam4.1687. PMID: 30030895Free PMC Article

Therapy

The emerging emetogenicity of trifluridine/tipiracil (TAS‑102) from patient self-reporting: a multicenter, prospective, observational study.
Fujii H, Tsuchiya M, Watanabe D, Otsuka R, Hirate D, Takahashi K, Go M, Kudo T, Shimomura K, Ando Y, Tani S, Takahashi T, Hayashi K, Chin M, Matsunami N, Takahashi M, Hasegawa A, Uchida T, Hashimoto H, Kubo A, Matsuhashi N, Suzuki A, Nishimura J, Inui N, Iihara H
Support Care Cancer 2024 Apr 17;32(5):291. doi: 10.1007/s00520-024-08498-z. PMID: 38630197
Disease and toxicity outcomes for a modern cohort of patients with squamous cell carcinoma of cutaneous origin involving the parotid gland: Comparison of volumetric modulated arc therapy and pencil beam scanning proton therapy.
Zarinshenas R, Campbell P, Sun K, Molitoris JK, Patel AN, Witek ME, Cullen KJ, Mehra R, Hatten KM, Moyer KF, Taylor RJ, Vakharia KT, Wolf JS, Ferris MJ
Radiother Oncol 2024 Apr;193:110112. Epub 2024 Feb 1 doi: 10.1016/j.radonc.2024.110112. PMID: 38309587
Taste alterations during neo/adjuvant chemotherapy and subsequent follow-up in breast cancer patients: a prospective single-center clinical study.
Pedersini R, Zamparini M, Bosio S, di Mauro P, Turla A, Monteverdi S, Zanini A, Amoroso V, Vassalli L, Cosentini D, Grisanti S, Simoncini EL, Berruti A
Support Care Cancer 2022 Aug;30(8):6955-6961. Epub 2022 May 11 doi: 10.1007/s00520-022-07091-6. PMID: 35538327
Multicenter, prospective, observational study of chemotherapy-induced dysgeusia in gastrointestinal cancer.
Ito K, Yuki S, Nakatsumi H, Kawamoto Y, Harada K, Nakano S, Saito R, Ando T, Sawada K, Yagisawa M, Ishiguro A, Dazai M, Iwanaga I, Hatanaka K, Sato A, Matsumoto R, Shindo Y, Tateyama M, Muranaka T, Katagiri M, Yokota I, Sakata Y, Sakamoto N, Komatsu Y
Support Care Cancer 2022 Jun;30(6):5351-5359. Epub 2022 Mar 15 doi: 10.1007/s00520-022-06936-4. PMID: 35292848Free PMC Article
Occurrence of Dysgeusia in Patients Being Treated for Cancer.
Di Meglio J, Dinu M, Doni L, Rossi G, Giorgione R, Colombini B, Antonuzzo L, Sofi F
Nutr Cancer 2022;74(8):2868-2874. Epub 2022 Feb 23 doi: 10.1080/01635581.2022.2042569. PMID: 35196919

Prognosis

Taste alterations during neo/adjuvant chemotherapy and subsequent follow-up in breast cancer patients: a prospective single-center clinical study.
Pedersini R, Zamparini M, Bosio S, di Mauro P, Turla A, Monteverdi S, Zanini A, Amoroso V, Vassalli L, Cosentini D, Grisanti S, Simoncini EL, Berruti A
Support Care Cancer 2022 Aug;30(8):6955-6961. Epub 2022 May 11 doi: 10.1007/s00520-022-07091-6. PMID: 35538327
Helical intensity-modulated radiotherapy with concurrent chemotherapy for oropharyngeal squamous cell carcinoma: A prospective investigation of acute swallowing and toxicity patterns.
Moroney LB, Helios J, Ward EC, Crombie J, Pelecanos A, Burns CL, Spurgin AL, Blake C, Kenny L, Chua B, Hughes BGM
Head Neck 2018 Sep;40(9):1955-1966. Epub 2018 May 13 doi: 10.1002/hed.25182. PMID: 29756244

Clinical prediction guides

The emerging emetogenicity of trifluridine/tipiracil (TAS‑102) from patient self-reporting: a multicenter, prospective, observational study.
Fujii H, Tsuchiya M, Watanabe D, Otsuka R, Hirate D, Takahashi K, Go M, Kudo T, Shimomura K, Ando Y, Tani S, Takahashi T, Hayashi K, Chin M, Matsunami N, Takahashi M, Hasegawa A, Uchida T, Hashimoto H, Kubo A, Matsuhashi N, Suzuki A, Nishimura J, Inui N, Iihara H
Support Care Cancer 2024 Apr 17;32(5):291. doi: 10.1007/s00520-024-08498-z. PMID: 38630197
Multicenter, prospective, observational study of chemotherapy-induced dysgeusia in gastrointestinal cancer.
Ito K, Yuki S, Nakatsumi H, Kawamoto Y, Harada K, Nakano S, Saito R, Ando T, Sawada K, Yagisawa M, Ishiguro A, Dazai M, Iwanaga I, Hatanaka K, Sato A, Matsumoto R, Shindo Y, Tateyama M, Muranaka T, Katagiri M, Yokota I, Sakata Y, Sakamoto N, Komatsu Y
Support Care Cancer 2022 Jun;30(6):5351-5359. Epub 2022 Mar 15 doi: 10.1007/s00520-022-06936-4. PMID: 35292848Free PMC Article
Occurrence of Dysgeusia in Patients Being Treated for Cancer.
Di Meglio J, Dinu M, Doni L, Rossi G, Giorgione R, Colombini B, Antonuzzo L, Sofi F
Nutr Cancer 2022;74(8):2868-2874. Epub 2022 Feb 23 doi: 10.1080/01635581.2022.2042569. PMID: 35196919
Big data analysis of associations between patient reported outcomes, observer reported toxicities, and overall quality of life in head and neck cancer patients treated with radiation therapy.
Wilkie JR, Mierzwa ML, Yao J, Eisbruch A, Feng M, Weyburne G, Chen X, Holevinski L, Mayo CS
Radiother Oncol 2019 Aug;137:167-174. Epub 2019 May 22 doi: 10.1016/j.radonc.2019.04.030. PMID: 31128357
Radiotherapy for cutaneous head and neck cancer and parotid tumours: a prospective investigation of treatment-related acute swallowing and toxicity patterns.
Moroney LB, Helios J, Ward EC, Crombie J, Burns CL, Yeo SQ, Pelecanos A, Spurgin AL, Blake C, Kenny L, Chua B, Hughes BGM
Support Care Cancer 2019 Feb;27(2):573-581. Epub 2018 Jul 17 doi: 10.1007/s00520-018-4352-5. PMID: 30019149

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