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Grade 1 Hemorrhoids, CTCAE

MedGen UID:
294709
•Concept ID:
C1560451
•
Finding

Definition

Asymptomatic; clinical or diagnostic observations only; intervention not indicated [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 1 Hemorrhoids, CTCAE

Professional guidelines

PubMed

Stereotactic body radiation therapy for the treatment of localized prostate cancer in men with underlying inflammatory bowel disease.
Lischalk JW, Blacksburg S, Mendez C, Repka M, Sanchez A, Carpenter T, Witten M, Garbus JE, Evans A, Collins SP, Katz A, Haas J
Radiat Oncol 2021 Jul 9;16(1):126. doi: 10.1186/s13014-021-01850-1. PMID: 34243797Free PMC Article

Recent clinical studies

Etiology

Health-related quality of life and patient-reported symptoms after postoperative proton beam radiotherapy of cervical and endometrial cancer: 2-year results of the prospective phase II APROVE-trial.
Meixner E, Wark A, Forster T, Weykamp F, Lang K, König L, Lindel K, Oelmann-Avendano JT, Krisam J, Schneeweiss A, Ellerbrock M, Mielke T, Hörner-Rieber J, Herfarth K, Debus J, Arians N
Radiat Oncol 2023 Jan 9;18(1):5. doi: 10.1186/s13014-023-02198-4. PMID: 36624483Free PMC Article
Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future.
Spampinato S, Jensen NBK, Pötter R, Fokdal LU, Chargari C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Hoskin P, Segedin B, Rai B, Bruheim K, Wiebe E, Van der Steen-Banasik E, Cooper R, Van Limbergen E, Sundset M, Pieters BR, Lutgens LCHW, Tan LT, Villafranca E, Smet S, Jastaniyah N, Nout RA, Kirisits C, Chopra S, Kirchheiner K, Tanderup K, Embrace Collaborative Group
Int J Radiat Oncol Biol Phys 2022 Mar 1;112(3):681-693. Epub 2021 Oct 20 doi: 10.1016/j.ijrobp.2021.09.055. PMID: 34678431
Outcomes of Squamous Cell Carcinoma Anal Canal treated with IMRT-VMAT-based Concurrent Chemoradiation: a Single Institutional Experience.
Singh K, Sathyamurthy A, Ramireddy JK, Ram TS
J Gastrointest Cancer 2022 Mar;53(1):161-169. Epub 2021 Jan 5 doi: 10.1007/s12029-020-00580-z. PMID: 33400211
Preliminary result of carbon-ion radiotherapy using the spot scanning method for prostate cancer.
Takakusagi Y, Katoh H, Kano K, Anno W, Tsuchida K, Mizoguchi N, Serizawa I, Yoshida D, Kamada T
Radiat Oncol 2020 May 27;15(1):127. doi: 10.1186/s13014-020-01575-7. PMID: 32460889Free PMC Article
Clinical outcomes with MRI-guided image-based brachytherapy in cervical cancer: An institutional experience.
Simha V, Rai B, Patel FD, Kapoor R, Sharma SC, Singh OA, Singla V, Dhanireddy B, Ghoshal S
Brachytherapy 2018 Mar-Apr;17(2):345-351. doi: 10.1016/j.brachy.2017.09.008. PMID: 29102740

Diagnosis

Comparing symptom reporting by prostate cancer patients and healthcare professionals in the international multicentre REQUITE study.
Heumann P, Aguado-Barrera ME, Avuzzi B, Azria D, Briers E, Bultijnck R, Choudhury A, De Ruysscher D, Farcy-Jacquet MP, Fonteyne V, Gómez Caamaño A, Helmbold I, Johnson K, Kerns SL, Lambrecht M, Lingard Z, Rancati T, Rosenstein BS, Sperk E, Paul Symonds R, Talbot C, Valdagni R, Vega A, Veldeman L, Ward T, Webb A, West CM, Chang-Claude J, Seibold P; REQUITE Consortium
Radiother Oncol 2023 Jan;178:109426. Epub 2022 Nov 25 doi: 10.1016/j.radonc.2022.11.015. PMID: 36442608
Stereotactic body radiation therapy for the treatment of localized prostate cancer in men with underlying inflammatory bowel disease.
Lischalk JW, Blacksburg S, Mendez C, Repka M, Sanchez A, Carpenter T, Witten M, Garbus JE, Evans A, Collins SP, Katz A, Haas J
Radiat Oncol 2021 Jul 9;16(1):126. doi: 10.1186/s13014-021-01850-1. PMID: 34243797Free PMC Article
Voxel-based population analysis for correlating local dose and rectal toxicity in prostate cancer radiotherapy.
Acosta O, Drean G, Ospina JD, Simon A, Haigron P, Lafond C, de Crevoisier R
Phys Med Biol 2013 Apr 21;58(8):2581-95. Epub 2013 Mar 26 doi: 10.1088/0031-9155/58/8/2581. PMID: 23528429Free PMC Article
Grading-system-dependent volume effects for late radiation-induced rectal toxicity after curative radiotherapy for prostate cancer.
van der Laan HP, van den Bergh A, Schilstra C, Vlasman R, Meertens H, Langendijk JA
Int J Radiat Oncol Biol Phys 2008 Mar 15;70(4):1138-45. Epub 2007 Oct 10 doi: 10.1016/j.ijrobp.2007.07.2363. PMID: 17931794
Rectal toxicity profile after transperineal interstitial permanent prostate brachytherapy: use of a comprehensive toxicity scoring system and identification of rectal dosimetric toxicity predictors.
Shah JN, Ennis RD
Int J Radiat Oncol Biol Phys 2006 Mar 1;64(3):817-24. Epub 2005 Nov 16 doi: 10.1016/j.ijrobp.2005.08.042. PMID: 16297567

Therapy

Radiobiological modeling of radiation-induced acute rectal mucositis: A single-institutional study of cervical carcinoma.
Singh B, Singh G, Oinam AS, Kumar V, Vashistha R, Sidhu MS, Singh M
J Cancer Res Ther 2023 Apr;19(Supplement):S0. doi: 10.4103/jcrt.jcrt_879_21. PMID: 37147948
Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future.
Spampinato S, Jensen NBK, Pötter R, Fokdal LU, Chargari C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Hoskin P, Segedin B, Rai B, Bruheim K, Wiebe E, Van der Steen-Banasik E, Cooper R, Van Limbergen E, Sundset M, Pieters BR, Lutgens LCHW, Tan LT, Villafranca E, Smet S, Jastaniyah N, Nout RA, Kirisits C, Chopra S, Kirchheiner K, Tanderup K, Embrace Collaborative Group
Int J Radiat Oncol Biol Phys 2022 Mar 1;112(3):681-693. Epub 2021 Oct 20 doi: 10.1016/j.ijrobp.2021.09.055. PMID: 34678431
Outcomes of Squamous Cell Carcinoma Anal Canal treated with IMRT-VMAT-based Concurrent Chemoradiation: a Single Institutional Experience.
Singh K, Sathyamurthy A, Ramireddy JK, Ram TS
J Gastrointest Cancer 2022 Mar;53(1):161-169. Epub 2021 Jan 5 doi: 10.1007/s12029-020-00580-z. PMID: 33400211
Preliminary result of carbon-ion radiotherapy using the spot scanning method for prostate cancer.
Takakusagi Y, Katoh H, Kano K, Anno W, Tsuchida K, Mizoguchi N, Serizawa I, Yoshida D, Kamada T
Radiat Oncol 2020 May 27;15(1):127. doi: 10.1186/s13014-020-01575-7. PMID: 32460889Free PMC Article
Clinical outcomes with MRI-guided image-based brachytherapy in cervical cancer: An institutional experience.
Simha V, Rai B, Patel FD, Kapoor R, Sharma SC, Singh OA, Singla V, Dhanireddy B, Ghoshal S
Brachytherapy 2018 Mar-Apr;17(2):345-351. doi: 10.1016/j.brachy.2017.09.008. PMID: 29102740

Prognosis

Dose-escalated radiotherapy to 82 Gy for prostate cancer following insertion of a peri-rectal hydrogel spacer: 3-year outcomes from a phase II trial.
See AW, Bowden P, Wells G, Appu S, Lawrentschuk N, Liodakis P, Pandeli C, Aarons Y, Smyth LML, McKenzie DP
Radiat Oncol 2022 Jul 25;17(1):131. doi: 10.1186/s13014-022-02103-5. PMID: 35879722Free PMC Article
Importance of the ICRU bladder point dose on incidence and persistence of urinary frequency and incontinence in locally advanced cervical cancer: An EMBRACE analysis.
Spampinato S, Fokdal LU, Pötter R, Haie-Meder C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Segedin B, Bruheim K, Hoskin P, Rai B, Huang F, Cooper R, van der Steen-Banasik E, Van Limbergen E, Sundset M, Westerveld H, Nout RA, Jensen NBK, Kirisits C, Kirchheiner K, Tanderup K; EMBRACE Collaborative Group
Radiother Oncol 2021 May;158:300-308. Epub 2020 Oct 14 doi: 10.1016/j.radonc.2020.10.003. PMID: 33065183
Preliminary result of carbon-ion radiotherapy using the spot scanning method for prostate cancer.
Takakusagi Y, Katoh H, Kano K, Anno W, Tsuchida K, Mizoguchi N, Serizawa I, Yoshida D, Kamada T
Radiat Oncol 2020 May 27;15(1):127. doi: 10.1186/s13014-020-01575-7. PMID: 32460889Free PMC Article
Clinical outcomes with MRI-guided image-based brachytherapy in cervical cancer: An institutional experience.
Simha V, Rai B, Patel FD, Kapoor R, Sharma SC, Singh OA, Singla V, Dhanireddy B, Ghoshal S
Brachytherapy 2018 Mar-Apr;17(2):345-351. doi: 10.1016/j.brachy.2017.09.008. PMID: 29102740
Proctitis following stereotactic body radiation therapy for prostate cancer.
Joh DY, Chen LN, Porter G, Bhagat A, Sood S, Kim JS, Moures R, Yung T, Lei S, Collins BT, Ju AW, Suy S, Carroll J, Lynch JH, Dritschilo A, Collins SP
Radiat Oncol 2014 Dec 12;9:277. doi: 10.1186/s13014-014-0277-4. PMID: 25497602Free PMC Article

Clinical prediction guides

Health-related quality of life and patient-reported symptoms after postoperative proton beam radiotherapy of cervical and endometrial cancer: 2-year results of the prospective phase II APROVE-trial.
Meixner E, Wark A, Forster T, Weykamp F, Lang K, König L, Lindel K, Oelmann-Avendano JT, Krisam J, Schneeweiss A, Ellerbrock M, Mielke T, Hörner-Rieber J, Herfarth K, Debus J, Arians N
Radiat Oncol 2023 Jan 9;18(1):5. doi: 10.1186/s13014-023-02198-4. PMID: 36624483Free PMC Article
Dose-escalated radiotherapy to 82 Gy for prostate cancer following insertion of a peri-rectal hydrogel spacer: 3-year outcomes from a phase II trial.
See AW, Bowden P, Wells G, Appu S, Lawrentschuk N, Liodakis P, Pandeli C, Aarons Y, Smyth LML, McKenzie DP
Radiat Oncol 2022 Jul 25;17(1):131. doi: 10.1186/s13014-022-02103-5. PMID: 35879722Free PMC Article
Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future.
Spampinato S, Jensen NBK, Pötter R, Fokdal LU, Chargari C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Hoskin P, Segedin B, Rai B, Bruheim K, Wiebe E, Van der Steen-Banasik E, Cooper R, Van Limbergen E, Sundset M, Pieters BR, Lutgens LCHW, Tan LT, Villafranca E, Smet S, Jastaniyah N, Nout RA, Kirisits C, Chopra S, Kirchheiner K, Tanderup K, Embrace Collaborative Group
Int J Radiat Oncol Biol Phys 2022 Mar 1;112(3):681-693. Epub 2021 Oct 20 doi: 10.1016/j.ijrobp.2021.09.055. PMID: 34678431
Preliminary result of carbon-ion radiotherapy using the spot scanning method for prostate cancer.
Takakusagi Y, Katoh H, Kano K, Anno W, Tsuchida K, Mizoguchi N, Serizawa I, Yoshida D, Kamada T
Radiat Oncol 2020 May 27;15(1):127. doi: 10.1186/s13014-020-01575-7. PMID: 32460889Free PMC Article
Proctitis following stereotactic body radiation therapy for prostate cancer.
Joh DY, Chen LN, Porter G, Bhagat A, Sood S, Kim JS, Moures R, Yung T, Lei S, Collins BT, Ju AW, Suy S, Carroll J, Lynch JH, Dritschilo A, Collins SP
Radiat Oncol 2014 Dec 12;9:277. doi: 10.1186/s13014-014-0277-4. PMID: 25497602Free PMC Article

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