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Intracranial aneurysm

MedGen UID:
2960
•Concept ID:
C0007766
•
Disease or Syndrome
Synonyms: Aneurysm, Intracranial; Aneurysms, Intracranial; Intracranial Aneurysm; Intracranial Aneurysms
SNOMED CT: Intracranial aneurysm (128609009)

Definition

A congenital or acquired aneurysm within the cranium. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntracranial aneurysm

Professional guidelines

PubMed

2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage: A Guideline From the American Heart Association/American Stroke Association.
Hoh BL, Ko NU, Amin-Hanjani S, Chou SH-Y, Cruz-Flores S, Dangayach NS, Derdeyn CP, Du R, Hänggi D, Hetts SW, Ifejika NL, Johnson R, Keigher KM, Leslie-Mazwi TM, Lucke-Wold B, Rabinstein AA, Robicsek SA, Stapleton CJ, Suarez JI, Tjoumakaris SI, Welch BG
Stroke 2023 Jul;54(7):e314-e370. Epub 2023 May 22 doi: 10.1161/STR.0000000000000436. PMID: 37212182
Diagnosis and Treatment of Unruptured Intracranial Aneurysms and Aneurysmal Subarachnoid Hemorrhage.
Tawk RG, Hasan TF, D'Souza CE, Peel JB, Freeman WD
Mayo Clin Proc 2021 Jul;96(7):1970-2000. Epub 2021 May 13 doi: 10.1016/j.mayocp.2021.01.005. PMID: 33992453
Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening.
Brown RD Jr, Broderick JP
Lancet Neurol 2014 Apr;13(4):393-404. doi: 10.1016/S1474-4422(14)70015-8. PMID: 24646873

Recent clinical studies

Etiology

Genetics of Intracranial Aneurysms.
Bakker MK, Ruigrok YM
Stroke 2021 Aug;52(9):3004-3012. Epub 2021 Aug 17 doi: 10.1161/STROKEAHA.120.032621. PMID: 34399582
Intracranial Vascular Procedures.
Gross WL, Sacho RH
Anesthesiol Clin 2021 Mar;39(1):1-18. Epub 2021 Jan 9 doi: 10.1016/j.anclin.2020.10.001. PMID: 33563374
Headache and Aneurysm.
Kwon OK
Neuroimaging Clin N Am 2019 May;29(2):255-260. Epub 2019 Feb 20 doi: 10.1016/j.nic.2019.01.004. PMID: 30926115
Unruptured Cerebral Aneurysms: Evaluation and Management.
Ajiboye N, Chalouhi N, Starke RM, Zanaty M, Bell R
ScientificWorldJournal 2015;2015:954954. Epub 2015 Jun 4 doi: 10.1155/2015/954954. PMID: 26146657Free PMC Article
Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening.
Brown RD Jr, Broderick JP
Lancet Neurol 2014 Apr;13(4):393-404. doi: 10.1016/S1474-4422(14)70015-8. PMID: 24646873

Diagnosis

Artificial Intelligence Applications in Intracranial Aneurysm: Achievements, Challenges and Opportunities.
Alwalid O, Long X, Xie M, Han P
Acad Radiol 2022 Mar;29 Suppl 3:S201-S214. Epub 2021 Aug 8 doi: 10.1016/j.acra.2021.06.013. PMID: 34376335
Headache and Aneurysm.
Kwon OK
Neuroimaging Clin N Am 2019 May;29(2):255-260. Epub 2019 Feb 20 doi: 10.1016/j.nic.2019.01.004. PMID: 30926115
Unruptured Cerebral Aneurysms: Evaluation and Management.
Ajiboye N, Chalouhi N, Starke RM, Zanaty M, Bell R
ScientificWorldJournal 2015;2015:954954. Epub 2015 Jun 4 doi: 10.1155/2015/954954. PMID: 26146657Free PMC Article
Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening.
Brown RD Jr, Broderick JP
Lancet Neurol 2014 Apr;13(4):393-404. doi: 10.1016/S1474-4422(14)70015-8. PMID: 24646873
Unruptured intracranial aneurysms.
Brown RD
Semin Neurol 2010 Nov;30(5):537-44. Epub 2011 Jan 4 doi: 10.1055/s-0030-1268858. PMID: 21207346

Therapy

Treatments for unruptured intracranial aneurysms.
Pontes FGB, da Silva EM, Baptista-Silva JC, Vasconcelos V
Cochrane Database Syst Rev 2021 May 10;5(5):CD013312. doi: 10.1002/14651858.CD013312.pub2. PMID: 33971026Free PMC Article
Unruptured Intracranial Aneurysms- Pathogenesis and Individualized Management.
Etminan N, Dörfler A, Steinmetz H
Dtsch Arztebl Int 2020 Apr 3;117(14):235-242. doi: 10.3238/arztebl.2020.0235. PMID: 32449895Free PMC Article
SCENT Trial.
Meyers PM, Coon AL, Kan PT, Wakhloo AK, Hanel RA
Stroke 2019 Jun;50(6):1473-1479. Epub 2019 May 14 doi: 10.1161/STROKEAHA.118.024135. PMID: 31084335
Calcium antagonists for aneurysmal subarachnoid haemorrhage.
Dorhout Mees SM, Rinkel GJ, Feigin VL, Algra A, van den Bergh WM, Vermeulen M, van Gijn J
Cochrane Database Syst Rev 2007 Jul 18;2007(3):CD000277. doi: 10.1002/14651858.CD000277.pub3. PMID: 17636626Free PMC Article
International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion.
Molyneux AJ, Kerr RS, Yu LM, Clarke M, Sneade M, Yarnold JA, Sandercock P; International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group
Lancet 2005 Sep 3-9;366(9488):809-17. doi: 10.1016/S0140-6736(05)67214-5. PMID: 16139655

Prognosis

Formation of intracranial de novo aneurysms and recurrence after neck clipping: a systematic review and meta-analysis.
Spiessberger A, Vogt DR, Fandino J, Marbacher S
J Neurosurg 2019 Feb 22;132(2):456-464. doi: 10.3171/2018.10.JNS181281. PMID: 30797217
Intraprocedural Rupture During Endovascular Treatment of Intracranial Aneurysm: Clinical Results and Literature Review.
Park YK, Yi HJ, Choi KS, Lee YJ, Chun HJ
World Neurosurg 2018 Jun;114:e605-e615. Epub 2018 Mar 14 doi: 10.1016/j.wneu.2018.03.040. PMID: 29548958
The association between lunar phase and intracranial aneurysm rupture: Myth or reality? Own data and systematic review.
Bunevicius A, Gendvilaite A, Deltuva VP, Tamasauskas A
BMC Neurol 2017 May 19;17(1):99. doi: 10.1186/s12883-017-0879-1. PMID: 28525979Free PMC Article
European Stroke Organization guidelines for the management of intracranial aneurysms and subarachnoid haemorrhage.
Steiner T, Juvela S, Unterberg A, Jung C, Forsting M, Rinkel G; European Stroke Organization
Cerebrovasc Dis 2013;35(2):93-112. Epub 2013 Feb 7 doi: 10.1159/000346087. PMID: 23406828
International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion.
Molyneux AJ, Kerr RS, Yu LM, Clarke M, Sneade M, Yarnold JA, Sandercock P; International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group
Lancet 2005 Sep 3-9;366(9488):809-17. doi: 10.1016/S0140-6736(05)67214-5. PMID: 16139655

Clinical prediction guides

Correlation of intracranial and aortic aneurysms: current trends and evidence.
Moughal S, Bashir M
Asian Cardiovasc Thorac Ann 2020 Jun;28(5):250-257. Epub 2020 Jun 2 doi: 10.1177/0218492320930848. PMID: 32486829
Prediction of Unruptured Intracranial Aneurysm Evolution: The UCAN Project.
L'Allinec V, Chatel S, Karakachoff M, Bourcereau E, Lamoureux Z, Gaignard A, Autrusseau F, Jouan S, Vion AC, Loirand G, Desal H, Naggara O, Redon R, Edjlali M, Bourcier R
Neurosurgery 2020 Jul 1;87(1):150-156. doi: 10.1093/neuros/nyaa093. PMID: 32374868
Cerebral Aneurysm Size before and after Rupture: Case Series and Literature Review.
Yi J, Zielinski D, Chen M
J Stroke Cerebrovasc Dis 2016 May;25(5):1244-1248. Epub 2016 Feb 27 doi: 10.1016/j.jstrokecerebrovasdis.2016.01.031. PMID: 26935121
Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies.
Greving JP, Wermer MJ, Brown RD Jr, Morita A, Juvela S, Yonekura M, Ishibashi T, Torner JC, Nakayama T, Rinkel GJ, Algra A
Lancet Neurol 2014 Jan;13(1):59-66. Epub 2013 Nov 27 doi: 10.1016/S1474-4422(13)70263-1. PMID: 24290159
European Stroke Organization guidelines for the management of intracranial aneurysms and subarachnoid haemorrhage.
Steiner T, Juvela S, Unterberg A, Jung C, Forsting M, Rinkel G; European Stroke Organization
Cerebrovasc Dis 2013;35(2):93-112. Epub 2013 Feb 7 doi: 10.1159/000346087. PMID: 23406828

Recent systematic reviews

Treatments for unruptured intracranial aneurysms.
Pontes FGB, da Silva EM, Baptista-Silva JC, Vasconcelos V
Cochrane Database Syst Rev 2021 May 10;5(5):CD013312. doi: 10.1002/14651858.CD013312.pub2. PMID: 33971026Free PMC Article
Worldwide Incidence of Aneurysmal Subarachnoid Hemorrhage According to Region, Time Period, Blood Pressure, and Smoking Prevalence in the Population: A Systematic Review and Meta-analysis.
Etminan N, Chang HS, Hackenberg K, de Rooij NK, Vergouwen MDI, Rinkel GJE, Algra A
JAMA Neurol 2019 May 1;76(5):588-597. doi: 10.1001/jamaneurol.2019.0006. PMID: 30659573Free PMC Article
Endovascular treatment of cerebral aneurysms using flow-diverter devices: A systematic review.
Briganti F, Leone G, Marseglia M, Mariniello G, Caranci F, Brunetti A, Maiuri F
Neuroradiol J 2015 Aug;28(4):365-75. Epub 2015 Aug 27 doi: 10.1177/1971400915602803. PMID: 26314872Free PMC Article
Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis.
Vlak MH, Algra A, Brandenburg R, Rinkel GJ
Lancet Neurol 2011 Jul;10(7):626-36. doi: 10.1016/S1474-4422(11)70109-0. PMID: 21641282
Calcium antagonists for aneurysmal subarachnoid haemorrhage.
Dorhout Mees SM, Rinkel GJ, Feigin VL, Algra A, van den Bergh WM, Vermeulen M, van Gijn J
Cochrane Database Syst Rev 2007 Jul 18;2007(3):CD000277. doi: 10.1002/14651858.CD000277.pub3. PMID: 17636626Free PMC Article

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