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Upper Extremity Dysfunction

MedGen UID:
306451
•Concept ID:
C1698635
•
Pathologic Function

Definition

Impaired functioning of the upper extremity. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUpper Extremity Dysfunction

Professional guidelines

PubMed

Rehabilitation Strategies Following Surgical Treatment of Upper Extremity Spasticity.
Petuchowksi J, Kieras K, Stein K
Hand Clin 2018 Nov;34(4):567-582. Epub 2018 Aug 20 doi: 10.1016/j.hcl.2018.06.013. PMID: 30286971
Canadian stroke best practice recommendations: Stroke rehabilitation practice guidelines, update 2015.
Hebert D, Lindsay MP, McIntyre A, Kirton A, Rumney PG, Bagg S, Bayley M, Dowlatshahi D, Dukelow S, Garnhum M, Glasser E, Halabi ML, Kang E, MacKay-Lyons M, Martino R, Rochette A, Rowe S, Salbach N, Semenko B, Stack B, Swinton L, Weber V, Mayer M, Verrilli S, DeVeber G, Andersen J, Barlow K, Cassidy C, Dilenge ME, Fehlings D, Hung R, Iruthayarajah J, Lenz L, Majnemer A, Purtzki J, Rafay M, Sonnenberg LK, Townley A, Janzen S, Foley N, Teasell R
Int J Stroke 2016 Jun;11(4):459-84. Epub 2016 Apr 14 doi: 10.1177/1747493016643553. PMID: 27079654
Management of upper extremity dysfunction in people with Parkinson disease and Huntington disease: facilitating outcomes across the disease lifespan.
Quinn L, Busse M, Dal Bello-Haas V
J Hand Ther 2013 Apr-Jun;26(2):148-54; quiz 155. Epub 2012 Dec 8 doi: 10.1016/j.jht.2012.11.001. PMID: 23231827

Recent clinical studies

Etiology

Effect of different constraint-induced movement therapy protocols on recovery of stroke survivors with upper extremity dysfunction: a systematic review and network meta-analysis.
Gao Q, Zhang Y, Long J, Pan M, Wang J, Yang F
Int J Rehabil Res 2023 Jun 1;46(2):133-150. Epub 2023 Apr 12 doi: 10.1097/MRR.0000000000000577. PMID: 37039604
The influence of axillary surgery and radiotherapeutic strategy on the risk of lymphedema and upper extremity dysfunction in early breast cancer patients.
Zheng SY, Chen CY, Qi WX, Cai G, Xu C, Cai R, Qian XF, Shen KW, Cao L, Chen JY
Breast 2023 Apr;68:142-148. Epub 2023 Feb 4 doi: 10.1016/j.breast.2023.02.001. PMID: 36764019Free PMC Article
Association between dysfunction of upper extremity and locomotive syndrome in general population.
Tajika T, Yamamoto A, Oya N, Okura C, Shinagawa S, Kitagawa T, Kobayashi H, Iizuka H, Takagishi K
J Orthop Sci 2017 Jan;22(1):144-148. Epub 2016 Dec 3 doi: 10.1016/j.jos.2016.11.004. PMID: 27919650
Management of upper extremity dysfunction in people with Parkinson disease and Huntington disease: facilitating outcomes across the disease lifespan.
Quinn L, Busse M, Dal Bello-Haas V
J Hand Ther 2013 Apr-Jun;26(2):148-54; quiz 155. Epub 2012 Dec 8 doi: 10.1016/j.jht.2012.11.001. PMID: 23231827
Idiopathic arm pain.
Ring D, Guss D, Malhotra L, Jupiter JB
J Bone Joint Surg Am 2004 Jul;86(7):1387-91. doi: 10.2106/00004623-200407000-00005. PMID: 15252084

Diagnosis

Treatment and Management of Upper Extremity Dysfunction Following Transradial Percutaneous Coronary Intervention: A Prospective Cohort Study.
Cheung ES, Zwaan EM, Schreuders TAR, Kofflard MJM, Coert JH, Alings M, IJsselmuiden AJJ, Holtzer CAJ
Hand (N Y) 2024 Jan;19(1):154-162. Epub 2022 Mar 4 doi: 10.1177/15589447211073832. PMID: 35245991Free PMC Article
Association between muscle strength, upper extremity fatigue resistance, work ability and upper extremity dysfunction in a sample of workers at a tertiary hospital.
Fifolato TM, Nardim HCB, do Carmo Lopes ER, Suzuki KAK, da Silva NC, de Souza Serenza F, Fonseca MCR
BMC Musculoskelet Disord 2021 Jun 1;22(1):508. doi: 10.1186/s12891-021-04256-y. PMID: 34074292Free PMC Article
Assessment of upper extremity function in multiple sclerosis: review and opinion.
Kraft GH, Amtmann D, Bennett SE, Finlayson M, Sutliff MH, Tullman M, Sidovar M, Rabinowicz AL
Postgrad Med 2014 Sep;126(5):102-8. doi: 10.3810/pgm.2014.09.2803. PMID: 25295653
Modified constraint-induced movement therapy versus traditional rehabilitation in patients with upper-extremity dysfunction after stroke: a systematic review and meta-analysis.
Shi YX, Tian JH, Yang KH, Zhao Y
Arch Phys Med Rehabil 2011 Jun;92(6):972-82. doi: 10.1016/j.apmr.2010.12.036. PMID: 21621674
Idiopathic arm pain.
Ring D, Guss D, Malhotra L, Jupiter JB
J Bone Joint Surg Am 2004 Jul;86(7):1387-91. doi: 10.2106/00004623-200407000-00005. PMID: 15252084

Therapy

Effectiveness of constraint-induced movement therapy (CIMT)-Telerehabilitation compared to traditional CIMT on upper extremity dysfunction of adult chronic stroke patients-A systematic review and meta-analysis.
Sanchez L, Asuncion BM, Tayag KR, Chua C, Escandor SJ, Dones VC 3rd
Physiother Res Int 2024 Jul;29(3):e2090. doi: 10.1002/pri.2090. PMID: 38685678
Effect of different constraint-induced movement therapy protocols on recovery of stroke survivors with upper extremity dysfunction: a systematic review and network meta-analysis.
Gao Q, Zhang Y, Long J, Pan M, Wang J, Yang F
Int J Rehabil Res 2023 Jun 1;46(2):133-150. Epub 2023 Apr 12 doi: 10.1097/MRR.0000000000000577. PMID: 37039604
The influence of axillary surgery and radiotherapeutic strategy on the risk of lymphedema and upper extremity dysfunction in early breast cancer patients.
Zheng SY, Chen CY, Qi WX, Cai G, Xu C, Cai R, Qian XF, Shen KW, Cao L, Chen JY
Breast 2023 Apr;68:142-148. Epub 2023 Feb 4 doi: 10.1016/j.breast.2023.02.001. PMID: 36764019Free PMC Article
Robot-assisted distal training improves upper limb dexterity and function after stroke: a systematic review and meta-regression.
Zhao M, Wang G, Wang A, Cheng LJ, Lau Y
Neurol Sci 2022 Mar;43(3):1641-1657. Epub 2022 Jan 28 doi: 10.1007/s10072-022-05913-3. PMID: 35089447
Evidence-based therapies for upper extremity dysfunction.
Liepert J
Curr Opin Neurol 2010 Dec;23(6):678-82. doi: 10.1097/WCO.0b013e32833ff4c4. PMID: 20852418

Prognosis

Is diabetes the risk factor for poor neurological recovery after cervical spine surgery? A review of the literature.
Wang P, Liu B, Rong T, Wu B
Eur J Med Res 2022 Nov 23;27(1):263. doi: 10.1186/s40001-022-00879-6. PMID: 36419189Free PMC Article
Home-based (virtual) rehabilitation improves motor and cognitive function for stroke patients: a randomized controlled trial of the Elements (EDNA-22) system.
Wilson PH, Rogers JM, Vogel K, Steenbergen B, McGuckian TB, Duckworth J
J Neuroeng Rehabil 2021 Nov 25;18(1):165. doi: 10.1186/s12984-021-00956-7. PMID: 34823545Free PMC Article
A comparison of the effects and usability of two exoskeletal robots with and without robotic actuation for upper extremity rehabilitation among patients with stroke: a single-blinded randomised controlled pilot study.
Park JH, Park G, Kim HY, Lee JY, Ham Y, Hwang D, Kwon S, Shin JH
J Neuroeng Rehabil 2020 Oct 19;17(1):137. doi: 10.1186/s12984-020-00763-6. PMID: 33076952Free PMC Article
Management of upper extremity dysfunction in people with Parkinson disease and Huntington disease: facilitating outcomes across the disease lifespan.
Quinn L, Busse M, Dal Bello-Haas V
J Hand Ther 2013 Apr-Jun;26(2):148-54; quiz 155. Epub 2012 Dec 8 doi: 10.1016/j.jht.2012.11.001. PMID: 23231827
A prospective surveillance model for rehabilitation for women with breast cancer.
Stout NL, Binkley JM, Schmitz KH, Andrews K, Hayes SC, Campbell KL, McNeely ML, Soballe PW, Berger AM, Cheville AL, Fabian C, Gerber LH, Harris SR, Johansson K, Pusic AL, Prosnitz RG, Smith RA
Cancer 2012 Apr 15;118(8 Suppl):2191-200. doi: 10.1002/cncr.27476. PMID: 22488693

Clinical prediction guides

Effect of different constraint-induced movement therapy protocols on recovery of stroke survivors with upper extremity dysfunction: a systematic review and network meta-analysis.
Gao Q, Zhang Y, Long J, Pan M, Wang J, Yang F
Int J Rehabil Res 2023 Jun 1;46(2):133-150. Epub 2023 Apr 12 doi: 10.1097/MRR.0000000000000577. PMID: 37039604
Association Between Upper-Extremity Health Condition and Depressive Status in an Elderly General Population.
Tajika T, Kuboi T, Oya N, Endo F, Shitara H, Ichinose T, Sasaki T, Hamano N, Chikuda H
Inquiry 2021 Jan-Dec;58:469580211059952. doi: 10.1177/00469580211059952. PMID: 34933574Free PMC Article
Association between dysfunction of upper extremity and locomotive syndrome in general population.
Tajika T, Yamamoto A, Oya N, Okura C, Shinagawa S, Kitagawa T, Kobayashi H, Iizuka H, Takagishi K
J Orthop Sci 2017 Jan;22(1):144-148. Epub 2016 Dec 3 doi: 10.1016/j.jos.2016.11.004. PMID: 27919650
Does pectoralis major flap harvesting induce upper extremity dysfunction?
Sun Q, Guo S, Wang D, Xu N, Jin SF, Wang CC
J Int Med Res 2015 Aug;43(4):555-9. Epub 2015 Jun 25 doi: 10.1177/0300060515579118. PMID: 26111774
Idiopathic arm pain.
Ring D, Guss D, Malhotra L, Jupiter JB
J Bone Joint Surg Am 2004 Jul;86(7):1387-91. doi: 10.2106/00004623-200407000-00005. PMID: 15252084

Recent systematic reviews

Effectiveness of constraint-induced movement therapy (CIMT)-Telerehabilitation compared to traditional CIMT on upper extremity dysfunction of adult chronic stroke patients-A systematic review and meta-analysis.
Sanchez L, Asuncion BM, Tayag KR, Chua C, Escandor SJ, Dones VC 3rd
Physiother Res Int 2024 Jul;29(3):e2090. doi: 10.1002/pri.2090. PMID: 38685678
Effect of different constraint-induced movement therapy protocols on recovery of stroke survivors with upper extremity dysfunction: a systematic review and network meta-analysis.
Gao Q, Zhang Y, Long J, Pan M, Wang J, Yang F
Int J Rehabil Res 2023 Jun 1;46(2):133-150. Epub 2023 Apr 12 doi: 10.1097/MRR.0000000000000577. PMID: 37039604
Robot-assisted distal training improves upper limb dexterity and function after stroke: a systematic review and meta-regression.
Zhao M, Wang G, Wang A, Cheng LJ, Lau Y
Neurol Sci 2022 Mar;43(3):1641-1657. Epub 2022 Jan 28 doi: 10.1007/s10072-022-05913-3. PMID: 35089447
Modified constraint-induced movement therapy versus traditional rehabilitation in patients with upper-extremity dysfunction after stroke: a systematic review and meta-analysis.
Shi YX, Tian JH, Yang KH, Zhao Y
Arch Phys Med Rehabil 2011 Jun;92(6):972-82. doi: 10.1016/j.apmr.2010.12.036. PMID: 21621674

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