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Large Intestinal Anastomotic Leakage

MedGen UID:
306504
Concept ID:
C1699327
Pathologic Function

Definition

Leakage due to breakdown of a large intestinal anastomosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLarge Intestinal Anastomotic Leakage

Professional guidelines

PubMed

van Workum F, Talboom K, Hannink G, Wolthuis A, de Lacy BF, Lefevre JH, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez RO, Konishi T, Panis Y, Rosman C, Hompes R, Tanis PJ, de Wilt JHW
Colorectal Dis 2021 Apr;23(4):982-988. Epub 2020 Dec 26 doi: 10.1111/codi.15435. PMID: 33169512Free PMC Article
Salgado CJ, Nugent A, Kuhn J, Janette M, Bahna H
Biomed Res Int 2018;2018:4907208. Epub 2018 May 10 doi: 10.1155/2018/4907208. PMID: 29862275Free PMC Article
Kingham TP, Pachter HL
J Am Coll Surg 2009 Feb;208(2):269-78. Epub 2008 Dec 4 doi: 10.1016/j.jamcollsurg.2008.10.015. PMID: 19228539

Recent clinical studies

Etiology

Greijdanus NG, Wienholts K, Ubels S, Talboom K, Hannink G, Wolthuis A, de Lacy FB, Lefevre JH, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez RO, Konishi T, Panis Y, Rutegård M, Hompes R, Rosman C, van Workum F, Tanis PJ, de Wilt JHW; TENTACLE-Rectum Collaborative Group
Ann Surg 2023 Nov 1;278(5):772-780. Epub 2023 Jul 27 doi: 10.1097/SLA.0000000000006043. PMID: 37498208Free PMC Article
van Praagh JB, de Wit JG, Olinga P, de Haan JJ, Nagengast WB, Fehrmann RSN, Havenga K
Br J Surg 2021 Apr 5;108(3):326-333. doi: 10.1093/bjs/znaa066. PMID: 33793728
Sciuto A, Merola G, De Palma GD, Sodo M, Pirozzi F, Bracale UM, Bracale U
World J Gastroenterol 2018 Jun 7;24(21):2247-2260. doi: 10.3748/wjg.v24.i21.2247. PMID: 29881234Free PMC Article
Sujatha-Bhaskar S, Jafari MD, Stamos MJ
Surg Technol Int 2017 Jul 25;30:83-88. PMID: 28277591
Slim K, Joris J, Beloeil H; Groupe Francophone de Réhabilitation Améliorée après Chirurgie (GRACE)
J Visc Surg 2016 Aug;153(4):269-75. Epub 2016 Jul 29 doi: 10.1016/j.jviscsurg.2016.06.011. PMID: 27480526

Diagnosis

Qin Q, Huang B, Wu A, Gao J, Liu X, Cao W, Ma T, Kuang Y, Guo J, Wu Q, Shao B, Guan Q, Yao H, Zhang X, Wang H; Chinese Radiation Intestinal Injury Research Group
Gastroenterology 2023 Dec;165(6):1430-1442.e14. Epub 2023 Aug 23 doi: 10.1053/j.gastro.2023.08.022. PMID: 37625498
Greijdanus NG, Wienholts K, Ubels S, Talboom K, Hannink G, Wolthuis A, de Lacy FB, Lefevre JH, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez RO, Konishi T, Panis Y, Rutegård M, Hompes R, Rosman C, van Workum F, Tanis PJ, de Wilt JHW; TENTACLE-Rectum Collaborative Group
Ann Surg 2023 Nov 1;278(5):772-780. Epub 2023 Jul 27 doi: 10.1097/SLA.0000000000006043. PMID: 37498208Free PMC Article
Zizzo M, Tumiati D, Bassi MC, Zanelli M, Sanguedolce F, Porpiglia F, Fiori C, Campobasso D, Castro Ruiz C, Bergamaschi FA, Maestroni UV, Carrieri G, Cormio L, Biolchini F, Palicelli A, Soriano A, Sassatelli R, Ascani S, Annessi V, Giunta A
Minerva Urol Nephrol 2022 Aug;74(4):400-408. Epub 2021 Nov 18 doi: 10.23736/S2724-6051.21.04750-9. PMID: 34791866
Bendifallah S, Puchar A, Vesale E, Moawad G, Daraï E, Roman H
J Minim Invasive Gynecol 2021 Mar;28(3):453-466. Epub 2020 Aug 22 doi: 10.1016/j.jmig.2020.08.015. PMID: 32841755
Dupré A, Slim K
J Visc Surg 2012 Oct;149(5):e287-8. Epub 2012 Oct 23 doi: 10.1016/j.jviscsurg.2012.10.009. PMID: 23092648

Therapy

Popivanov GI, Mutafchiyski VM, Cirocchi R, Chipeva SD, Vasilev VV, Kjossev KT, Tabakov MS
Colorectal Dis 2020 Mar;22(3):243-253. Epub 2019 Jul 19 doi: 10.1111/codi.14754. PMID: 31274227
Meyer J, Naiken S, Christou N, Liot E, Toso C, Buchs NC, Ris F
World J Gastroenterol 2019 Sep 14;25(34):5017-5025. doi: 10.3748/wjg.v25.i34.5017. PMID: 31558854Free PMC Article
Sciuto A, Merola G, De Palma GD, Sodo M, Pirozzi F, Bracale UM, Bracale U
World J Gastroenterol 2018 Jun 7;24(21):2247-2260. doi: 10.3748/wjg.v24.i21.2247. PMID: 29881234Free PMC Article
Ellebæk M, Qvist N
Tech Coloproctol 2014 Jan;18(1):1-2. Epub 2013 Apr 30 doi: 10.1007/s10151-013-1025-8. PMID: 23633242
Dupré A, Slim K
J Visc Surg 2012 Oct;149(5):e287-8. Epub 2012 Oct 23 doi: 10.1016/j.jviscsurg.2012.10.009. PMID: 23092648

Prognosis

Greijdanus NG, Wienholts K, Ubels S, Talboom K, Hannink G, Wolthuis A, de Lacy FB, Lefevre JH, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez RO, Konishi T, Panis Y, Rutegård M, Hompes R, Rosman C, van Workum F, Tanis PJ, de Wilt JHW; TENTACLE-Rectum Collaborative Group
Ann Surg 2023 Nov 1;278(5):772-780. Epub 2023 Jul 27 doi: 10.1097/SLA.0000000000006043. PMID: 37498208Free PMC Article
Meyer J, Naiken S, Christou N, Liot E, Toso C, Buchs NC, Ris F
World J Gastroenterol 2019 Sep 14;25(34):5017-5025. doi: 10.3748/wjg.v25.i34.5017. PMID: 31558854Free PMC Article
Sciuto A, Merola G, De Palma GD, Sodo M, Pirozzi F, Bracale UM, Bracale U
World J Gastroenterol 2018 Jun 7;24(21):2247-2260. doi: 10.3748/wjg.v24.i21.2247. PMID: 29881234Free PMC Article
Kawada K, Sakai Y
World J Gastroenterol 2016 Jul 7;22(25):5718-27. doi: 10.3748/wjg.v22.i25.5718. PMID: 27433085Free PMC Article
Skinner DB
Am J Surg 1980 Jun;139(6):810-4. doi: 10.1016/0002-9610(80)90387-6. PMID: 7386734

Clinical prediction guides

Greijdanus NG, Wienholts K, Ubels S, Talboom K, Hannink G, Wolthuis A, de Lacy FB, Lefevre JH, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez RO, Konishi T, Panis Y, Rutegård M, Hompes R, Rosman C, van Workum F, Tanis PJ, de Wilt JHW; TENTACLE-Rectum Collaborative Group
Ann Surg 2023 Nov 1;278(5):772-780. Epub 2023 Jul 27 doi: 10.1097/SLA.0000000000006043. PMID: 37498208Free PMC Article
Jin D, Chen L
Medicine (Baltimore) 2021 Jun 4;100(22):e26196. doi: 10.1097/MD.0000000000026196. PMID: 34087889Free PMC Article
Shiwakoti E, Song J, Li J, Wu S, Zhang Z
J Int Med Res 2020 Sep;48(9):300060520957547. doi: 10.1177/0300060520957547. PMID: 32962496Free PMC Article
Sciuto A, Merola G, De Palma GD, Sodo M, Pirozzi F, Bracale UM, Bracale U
World J Gastroenterol 2018 Jun 7;24(21):2247-2260. doi: 10.3748/wjg.v24.i21.2247. PMID: 29881234Free PMC Article
Raptis D, Pramateftakis MG, Kanellos I
J Med Life 2018 Jan-Mar;11(1):5-14. PMID: 29696058Free PMC Article

Recent systematic reviews

Zizzo M, Tumiati D, Bassi MC, Zanelli M, Sanguedolce F, Porpiglia F, Fiori C, Campobasso D, Castro Ruiz C, Bergamaschi FA, Maestroni UV, Carrieri G, Cormio L, Biolchini F, Palicelli A, Soriano A, Sassatelli R, Ascani S, Annessi V, Giunta A
Minerva Urol Nephrol 2022 Aug;74(4):400-408. Epub 2021 Nov 18 doi: 10.23736/S2724-6051.21.04750-9. PMID: 34791866
Bendifallah S, Puchar A, Vesale E, Moawad G, Daraï E, Roman H
J Minim Invasive Gynecol 2021 Mar;28(3):453-466. Epub 2020 Aug 22 doi: 10.1016/j.jmig.2020.08.015. PMID: 32841755
Slim K, Joris J, Beloeil H; Groupe Francophone de Réhabilitation Améliorée après Chirurgie (GRACE)
J Visc Surg 2016 Aug;153(4):269-75. Epub 2016 Jul 29 doi: 10.1016/j.jviscsurg.2016.06.011. PMID: 27480526
Rondelli F, Bugiantella W, Vedovati MC, Balzarotti R, Avenia N, Mariani E, Agnelli G, Becattini C
Colorectal Dis 2014 Feb;16(2):O35-42. doi: 10.1111/codi.12491. PMID: 24245821
Wu Z, Boersema GS, Vakalopoulos KA, Daams F, Sparreboom CL, Kleinrensink GJ, Jeekel J, Lange JF
J Biomed Mater Res B Appl Biomater 2014 Apr;102(3):635-42. Epub 2013 Oct 24 doi: 10.1002/jbm.b.33039. PMID: 24155114

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