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Cerebral abscess

MedGen UID:
307135
•Concept ID:
C1510428
•
Disease or Syndrome
Synonyms: Abscess, Cerebral; Abscesses, Cerebral; Cerebral Abscess; Cerebral Abscesses
SNOMED CT: Cerebral abscess (60404007); Parenchymal intracranial abscess (60404007)

Definition

A bacterial, fungal, or parasitic abscess that develops in the cerebral hemispheres. Causes include skull trauma, middle ear infection, congenital heart disease, and frontal and ethmoid sinus infection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCerebral abscess

Professional guidelines

PubMed

Diagnosis and endovascular management of pulmonary arteriovenous malformations.
Kramdhari H, Valakkada J, Ayyappan A
Br J Radiol 2021 Jul 1;94(1123):20200695. Epub 2021 May 26 doi: 10.1259/bjr.20200695. PMID: 34038182Free PMC Article
Diagnosis, management and treatment of orbital and periorbital cellulitis in children.
Rashed F, Cannon A, Heaton PA, Paul SP
Emerg Nurse 2016 Apr;24(1):30-5; quiz 37. doi: 10.7748/en.24.1.30.s25. PMID: 27056016
Diagnosis and treatment of pulmonary arteriovenous malformations in hereditary hemorrhagic telangiectasia: An overview.
Lacombe P, Lacout A, Marcy PY, Binsse S, Sellier J, Bensalah M, Chinet T, Bourgault-Villada I, Blivet S, Roume J, Lesur G, Blondel JH, Fagnou C, Ozanne A, Chagnon S, El Hajjam M
Diagn Interv Imaging 2013 Sep;94(9):835-48. Epub 2013 Jun 12 doi: 10.1016/j.diii.2013.03.014. PMID: 23763987

Recent clinical studies

Etiology

The connection between brain abscess and odontogenic infections: A systematic review.
Lisboa ECC, Silva WO, Rodrigues RCV, Brum SC, Alves FRF
Arch Oral Biol 2022 Mar;135:105360. Epub 2022 Jan 31 doi: 10.1016/j.archoralbio.2022.105360. PMID: 35121265
Brain abscess in pediatric age: a review.
Mameli C, Genoni T, Madia C, Doneda C, Penagini F, Zuccotti G
Childs Nerv Syst 2019 Jul;35(7):1117-1128. Epub 2019 May 6 doi: 10.1007/s00381-019-04182-4. PMID: 31062139
Embolisation for pulmonary arteriovenous malformation.
Hsu CC, Kwan GN, Evans-Barns H, van Driel ML
Cochrane Database Syst Rev 2018 Jan 4;1(1):CD008017. doi: 10.1002/14651858.CD008017.pub5. PMID: 29298459Free PMC Article
Cerebral abscess after neuro-vascular embolization: Own experience and review of the literature.
Cossu G, Daniel RT, Messerer M
Acta Neurochir (Wien) 2017 Mar;159(3):583-591. Epub 2017 Jan 23 doi: 10.1007/s00701-016-3069-9. PMID: 28116528
Pulmonary arteriovenous malformations.
Cartin-Ceba R, Swanson KL, Krowka MJ
Chest 2013 Sep;144(3):1033-1044. doi: 10.1378/chest.12-0924. PMID: 24008954

Diagnosis

Role of imaging in CNS infections.
Sharath Kumar GG, Adiga CP, Iyer PP, Goolahally LN
Indian J Pathol Microbiol 2022 May;65(Supplement):S153-S163. doi: 10.4103/ijpm.ijpm_1162_21. PMID: 35562146
Brain abscess in pediatric age: a review.
Mameli C, Genoni T, Madia C, Doneda C, Penagini F, Zuccotti G
Childs Nerv Syst 2019 Jul;35(7):1117-1128. Epub 2019 May 6 doi: 10.1007/s00381-019-04182-4. PMID: 31062139
Pulmonary arteriovenous malformations.
Cartin-Ceba R, Swanson KL, Krowka MJ
Chest 2013 Sep;144(3):1033-1044. doi: 10.1378/chest.12-0924. PMID: 24008954
Maxillofacial cellulitis.
de-Vicente-Rodríguez JC
Med Oral Patol Oral Cir Bucal 2004;9 Suppl:133-8; 126-33. PMID: 15580131
Cerebral abscess.
Williams B
Br J Neurosurg 1990;4(4):248-51. doi: 10.3109/02688699008992733. PMID: 1977413

Therapy

Nocardia spp.: A Rare Cause of Pneumonia Globally.
Lynch JP 3rd, Reid G, Clark NM
Semin Respir Crit Care Med 2020 Aug;41(4):538-554. Epub 2020 Jul 6 doi: 10.1055/s-0040-1708816. PMID: 32629491
Brain abscess in pediatric age: a review.
Mameli C, Genoni T, Madia C, Doneda C, Penagini F, Zuccotti G
Childs Nerv Syst 2019 Jul;35(7):1117-1128. Epub 2019 May 6 doi: 10.1007/s00381-019-04182-4. PMID: 31062139
Embolisation for pulmonary arteriovenous malformation.
Hsu CC, Kwan GN, Evans-Barns H, van Driel ML
Cochrane Database Syst Rev 2018 Jan 4;1(1):CD008017. doi: 10.1002/14651858.CD008017.pub5. PMID: 29298459Free PMC Article
Cerebral nocardiosis.
Naqi R, Ahsan H, Azeemuddin M
J Pak Med Assoc 2011 Jul;61(7):697-9. PMID: 22204250
Maxillofacial cellulitis.
de-Vicente-Rodríguez JC
Med Oral Patol Oral Cir Bucal 2004;9 Suppl:133-8; 126-33. PMID: 15580131

Prognosis

First case report of cerebral abscess from Nocardia terpenica and literature review.
Sher M, Heard T, Munckhof W, Schwindack C
Clin Neurol Neurosurg 2022 Sep;220:107341. Epub 2022 Jun 21 doi: 10.1016/j.clineuro.2022.107341. PMID: 35779502
Predictors of reoperation and noninfectious complications following craniotomy for cerebral abscess.
Longo M, Feigen C, De la Garza Ramos R, Gelfand Y, Echt M, Agarwal V
Clin Neurol Neurosurg 2019 Apr;179:55-59. Epub 2019 Feb 27 doi: 10.1016/j.clineuro.2019.02.020. PMID: 30844618
Neurological sequelae of bacterial meningitis.
Lucas MJ, Brouwer MC, van de Beek D
J Infect 2016 Jul;73(1):18-27. Epub 2016 Apr 19 doi: 10.1016/j.jinf.2016.04.009. PMID: 27105658
Pulmonary arteriovenous malformations.
Cartin-Ceba R, Swanson KL, Krowka MJ
Chest 2013 Sep;144(3):1033-1044. doi: 10.1378/chest.12-0924. PMID: 24008954
Neurosurgical aspects of central nervous system infections.
Heth JA
Neuroimaging Clin N Am 2012 Nov;22(4):791-9. doi: 10.1016/j.nic.2012.05.005. PMID: 23122267

Clinical prediction guides

Early switch to oral antimicrobials in brain abscess: a narrative review.
Bodilsen J, Nielsen H
Clin Microbiol Infect 2023 Sep;29(9):1139-1143. Epub 2023 Apr 28 doi: 10.1016/j.cmi.2023.04.026. PMID: 37119987
Brain abscess in pediatric age: a review.
Mameli C, Genoni T, Madia C, Doneda C, Penagini F, Zuccotti G
Childs Nerv Syst 2019 Jul;35(7):1117-1128. Epub 2019 May 6 doi: 10.1007/s00381-019-04182-4. PMID: 31062139
Predictors of reoperation and noninfectious complications following craniotomy for cerebral abscess.
Longo M, Feigen C, De la Garza Ramos R, Gelfand Y, Echt M, Agarwal V
Clin Neurol Neurosurg 2019 Apr;179:55-59. Epub 2019 Feb 27 doi: 10.1016/j.clineuro.2019.02.020. PMID: 30844618
Embolisation for pulmonary arteriovenous malformation.
Hsu CC, Kwan GN, Evans-Barns H, van Driel ML
Cochrane Database Syst Rev 2018 Jan 4;1(1):CD008017. doi: 10.1002/14651858.CD008017.pub5. PMID: 29298459Free PMC Article
Embolisation for pulmonary arteriovenous malformation.
Hsu CC, Kwan GN, Thompson SA, Evans-Barns H, van Driel ML
Cochrane Database Syst Rev 2015 Jan 29;1:CD008017. doi: 10.1002/14651858.CD008017.pub4. PMID: 25634560

Recent systematic reviews

The connection between brain abscess and odontogenic infections: A systematic review.
Lisboa ECC, Silva WO, Rodrigues RCV, Brum SC, Alves FRF
Arch Oral Biol 2022 Mar;135:105360. Epub 2022 Jan 31 doi: 10.1016/j.archoralbio.2022.105360. PMID: 35121265
Nocardia farcinica cerebral abscess: A systematic review of treatment strategies.
Beucler N, Farah K, Choucha A, Meyer M, Fuentes S, Seng P, Dufour H
Neurochirurgie 2022 Jan;68(1):94-101. Epub 2021 May 11 doi: 10.1016/j.neuchi.2021.04.022. PMID: 33989644
Embolisation for pulmonary arteriovenous malformation.
Hsu CC, Kwan GN, Evans-Barns H, van Driel ML
Cochrane Database Syst Rev 2018 Jan 4;1(1):CD008017. doi: 10.1002/14651858.CD008017.pub5. PMID: 29298459Free PMC Article
Central nervous system melioidosis in the pediatric age group: review.
Prasad GL, Kini P, Divya S
Childs Nerv Syst 2017 Jun;33(6):1-6. Epub 2017 Apr 27 doi: 10.1007/s00381-017-3422-1. PMID: 28451778
Embolisation for pulmonary arteriovenous malformation.
Hsu CC, Kwan GN, Thompson SA, Evans-Barns H, van Driel ML
Cochrane Database Syst Rev 2015 Jan 29;1:CD008017. doi: 10.1002/14651858.CD008017.pub4. PMID: 25634560

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