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Chronic uveitis

MedGen UID:
307139
Concept ID:
C1510449
Disease or Syndrome
Synonyms: Chronic inflammation of uveal tract; Chronic Iridocyclitis
SNOMED CT: Chronic inflammation of uveal tract (444248002); Chronic uveitis (444248002)

Definition

Uveitis that is usually insidious in onset, bilateral, and can be asymptomatic, most often affecting the anterior uveal tract, including the iris and ciliary body, and can result in long-term complications. It is most commonly associated with certain forms of juvenile idiopathic arthritis, but may occur independent of arthritis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic uveitis

Professional guidelines

PubMed

Quartier P, Saadoun D, Belot A, Errera MH, Kaplanski G, Kodjikian L, Kone-Paut I, Miceli-Richard C, Monnet D, Audouin-Pajot C, Seve P, Uettwiller F, Weber M, Bodaghi B; Collaborators
Rev Med Interne 2023 May;44(5):227-252. Epub 2023 May 3 doi: 10.1016/j.revmed.2023.04.002. PMID: 37147233
Maccora I, Marrani E, Pagnini I, Mastrolia MV, de Libero C, Caputo R, Simonini G
Expert Rev Clin Immunol 2023 Jun;19(6):599-611. Epub 2023 Apr 3 doi: 10.1080/1744666X.2023.2198210. PMID: 36996498
Levy-Clarke GA, Nussenblatt RB, Smith JA
Curr Opin Ophthalmol 2005 Oct;16(5):281-8. doi: 10.1097/01.icu.0000177414.79030.32. PMID: 16175040

Recent clinical studies

Etiology

Maccora I, Marrani E, Pagnini I, Mastrolia MV, de Libero C, Caputo R, Simonini G
Expert Rev Clin Immunol 2023 Jun;19(6):599-611. Epub 2023 Apr 3 doi: 10.1080/1744666X.2023.2198210. PMID: 36996498
Fardeau C, Alafaleq M, Dhaenens CM, Dollfus H, Koné-Paut I, Grunewald O, Morel JB, Titah C, Saadoun D, Lazeran PO, Meunier I
Clin Genet 2023 Apr;103(4):453-458. Epub 2022 Dec 30 doi: 10.1111/cge.14286. PMID: 36543582
Kumar P, Gupta A, Bansal R, Suri D, Gupta V, Gupta A, Singh S
Indian J Pediatr 2022 Apr;89(4):358-363. Epub 2021 Nov 3 doi: 10.1007/s12098-021-03884-5. PMID: 34731440
Accorinti M, Okada AA, Smith JR, Gilardi M
Ocul Immunol Inflamm 2019;27(2):169-180. Epub 2019 Mar 1 doi: 10.1080/09273948.2019.1576910. PMID: 30821631
Sève P, Cacoub P, Bodaghi B, Trad S, Sellam J, Bellocq D, Bielefeld P, Sène D, Kaplanski G, Monnet D, Brézin A, Weber M, Saadoun D, Chiquet C, Kodjikian L
Autoimmun Rev 2017 Dec;16(12):1254-1264. Epub 2017 Oct 14 doi: 10.1016/j.autrev.2017.10.010. PMID: 29037906

Diagnosis

Maccora I, Marrani E, Pagnini I, Mastrolia MV, de Libero C, Caputo R, Simonini G
Expert Rev Clin Immunol 2023 Jun;19(6):599-611. Epub 2023 Apr 3 doi: 10.1080/1744666X.2023.2198210. PMID: 36996498
Fardeau C, Alafaleq M, Dhaenens CM, Dollfus H, Koné-Paut I, Grunewald O, Morel JB, Titah C, Saadoun D, Lazeran PO, Meunier I
Clin Genet 2023 Apr;103(4):453-458. Epub 2022 Dec 30 doi: 10.1111/cge.14286. PMID: 36543582
Kumar P, Gupta A, Bansal R, Suri D, Gupta V, Gupta A, Singh S
Indian J Pediatr 2022 Apr;89(4):358-363. Epub 2021 Nov 3 doi: 10.1007/s12098-021-03884-5. PMID: 34731440
Pilania RK, Singh S
Indian Pediatr 2019 May 15;56(5):407-414. PMID: 31102381
Sève P, Cacoub P, Bodaghi B, Trad S, Sellam J, Bellocq D, Bielefeld P, Sène D, Kaplanski G, Monnet D, Brézin A, Weber M, Saadoun D, Chiquet C, Kodjikian L
Autoimmun Rev 2017 Dec;16(12):1254-1264. Epub 2017 Oct 14 doi: 10.1016/j.autrev.2017.10.010. PMID: 29037906

Therapy

Quartier P, Saadoun D, Belot A, Errera MH, Kaplanski G, Kodjikian L, Kone-Paut I, Miceli-Richard C, Monnet D, Audouin-Pajot C, Seve P, Uettwiller F, Weber M, Bodaghi B; Collaborators
Rev Med Interne 2023 May;44(5):227-252. Epub 2023 May 3 doi: 10.1016/j.revmed.2023.04.002. PMID: 37147233
Maccora I, Marrani E, Pagnini I, Mastrolia MV, de Libero C, Caputo R, Simonini G
Expert Rev Clin Immunol 2023 Jun;19(6):599-611. Epub 2023 Apr 3 doi: 10.1080/1744666X.2023.2198210. PMID: 36996498
Zagora SL, McCluskey P
Curr Opin Ophthalmol 2014 Nov;25(6):495-501. doi: 10.1097/ICU.0000000000000098. PMID: 25260061
Mesquida M, Leszczynska A, Llorenç V, Adán A
Clin Exp Immunol 2014 Jun;176(3):301-9. doi: 10.1111/cei.12295. PMID: 24528300Free PMC Article
Islam N, Pavesio C
BMJ Clin Evid 2010 Apr 8;2010 PMID: 21736765Free PMC Article

Prognosis

Fardeau C, Alafaleq M, Dhaenens CM, Dollfus H, Koné-Paut I, Grunewald O, Morel JB, Titah C, Saadoun D, Lazeran PO, Meunier I
Clin Genet 2023 Apr;103(4):453-458. Epub 2022 Dec 30 doi: 10.1111/cge.14286. PMID: 36543582
Accorinti M, Okada AA, Smith JR, Gilardi M
Ocul Immunol Inflamm 2019;27(2):169-180. Epub 2019 Mar 1 doi: 10.1080/09273948.2019.1576910. PMID: 30821631
Bou R, Iglesias E, Antón J
Curr Rheumatol Rep 2014 Aug;16(8):437. doi: 10.1007/s11926-014-0437-4. PMID: 24938442
Allen D
BMJ Clin Evid 2011 Feb 15;2011 PMID: 21718561Free PMC Article
Islam N, Pavesio C
BMJ Clin Evid 2010 Apr 8;2010 PMID: 21736765Free PMC Article

Clinical prediction guides

Fardeau C, Alafaleq M, Dhaenens CM, Dollfus H, Koné-Paut I, Grunewald O, Morel JB, Titah C, Saadoun D, Lazeran PO, Meunier I
Clin Genet 2023 Apr;103(4):453-458. Epub 2022 Dec 30 doi: 10.1111/cge.14286. PMID: 36543582
Accorinti M, Okada AA, Smith JR, Gilardi M
Ocul Immunol Inflamm 2019;27(2):169-180. Epub 2019 Mar 1 doi: 10.1080/09273948.2019.1576910. PMID: 30821631
Li CQ, Cho AA, Edward NJ, Edward DP, Fajardo RG, Mafee MF
Neuroradiology 2015 Aug;57(8):825-32. Epub 2015 Apr 24 doi: 10.1007/s00234-015-1531-7. PMID: 25903430
Allen D
BMJ Clin Evid 2011 Feb 15;2011 PMID: 21718561Free PMC Article
Islam N, Pavesio C
BMJ Clin Evid 2010 Apr 8;2010 PMID: 21736765Free PMC Article

Recent systematic reviews

Simonini G, Cimaz R, Jones GT, Macfarlane GJ
Semin Arthritis Rheum 2015 Oct;45(2):238-50. Epub 2015 May 21 doi: 10.1016/j.semarthrit.2015.05.006. PMID: 26164255
Simonini G, Druce K, Cimaz R, Macfarlane GJ, Jones GT
Arthritis Care Res (Hoboken) 2014 Jul;66(7):1073-84. doi: 10.1002/acr.22214. PMID: 24740981
Simonini G, Katie D, Cimaz R, Macfarlane GJ, Jones GT
Semin Arthritis Rheum 2014 Aug;44(1):39-46. Epub 2014 Mar 6 doi: 10.1016/j.semarthrit.2014.03.001. PMID: 24709278
Allen D
BMJ Clin Evid 2011 Feb 15;2011 PMID: 21718561Free PMC Article
Islam N, Pavesio C
BMJ Clin Evid 2010 Apr 8;2010 PMID: 21736765Free PMC Article

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