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Angiogenic Switch

MedGen UID:
307205
Concept ID:
C1510885
Neoplastic Process

Definition

Loss of the balance between stimulation and inhibition of new blood vessel growth. A required early step in cancer growth and metastasis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAngiogenic Switch

Professional guidelines

PubMed

Locatelli M, Curigliano G
Curr Opin Oncol 2017 Nov;29(6):411-427. doi: 10.1097/CCO.0000000000000406. PMID: 28914645
Livesey KM, Tang D, Zeh HJ, Lotze MT
Curr Opin Investig Drugs 2009 Dec;10(12):1269-79. PMID: 19943199
Rosenblatt MI, Azar DT
Semin Ophthalmol 2006 Jul-Sep;21(3):151-60. doi: 10.1080/08820530500350787. PMID: 16912013

Recent clinical studies

Etiology

Asokan S, Bandapalli OR
Adv Exp Med Biol 2021;1302:25-39. doi: 10.1007/978-3-030-62658-7_3. PMID: 34286439
Groblewska M, Litman-Zawadzka A, Mroczko B
Int J Mol Sci 2020 May 24;21(10) doi: 10.3390/ijms21103704. PMID: 32456359Free PMC Article
Joo YY, Jang JW, Lee SW, Yoo SH, Kwon JH, Nam SW, Bae SH, Choi JY, Yoon SK
Sci Rep 2019 Jun 24;9(1):9137. doi: 10.1038/s41598-019-45537-w. PMID: 31235729Free PMC Article
Angelillo-Scherrer A
Circ Res 2012 Jan 20;110(2):356-69. doi: 10.1161/CIRCRESAHA.110.233403. PMID: 22267840
Zhong H, Bowen JP
Curr Med Chem 2006;13(8):849-62. doi: 10.2174/092986706776361085. PMID: 16611071

Diagnosis

Manuelli V, Pecorari C, Filomeni G, Zito E
FEBS J 2022 Sep;289(18):5413-5425. Epub 2021 Jul 16 doi: 10.1111/febs.16110. PMID: 34228878
Reuss AM, Groos D, Buchfelder M, Savaskan N
Int J Mol Sci 2021 May 24;22(11) doi: 10.3390/ijms22115518. PMID: 34073734Free PMC Article
March B, Faulkner S, Jobling P, Steigler A, Blatt A, Denham J, Hondermarck H
Nat Rev Urol 2020 Feb;17(2):119-130. Epub 2020 Jan 14 doi: 10.1038/s41585-019-0274-3. PMID: 31937919
Rajabi S, Dehghan MH, Dastmalchi R, Jalali Mashayekhi F, Salami S, Hedayati M
Endocr J 2019 Apr 25;66(4):277-293. Epub 2019 Mar 6 doi: 10.1507/endocrj.EJ18-0537. PMID: 30842365
Brinton LT, Sloane HS, Kester M, Kelly KA
Cell Mol Life Sci 2015 Feb;72(4):659-71. Epub 2014 Oct 22 doi: 10.1007/s00018-014-1764-3. PMID: 25336151Free PMC Article

Therapy

Papadimitriou M, Papadimitriou CA
Anticancer Res 2021 Feb;41(2):567-582. doi: 10.21873/anticanres.14809. PMID: 33517262
De Sanctis F, Ugel S, Facciponte J, Facciabene A
Semin Immunol 2018 Feb;35:35-47. Epub 2018 Feb 26 doi: 10.1016/j.smim.2018.02.002. PMID: 29490888
Wang Z, Dabrosin C, Yin X, Fuster MM, Arreola A, Rathmell WK, Generali D, Nagaraju GP, El-Rayes B, Ribatti D, Chen YC, Honoki K, Fujii H, Georgakilas AG, Nowsheen S, Amedei A, Niccolai E, Amin A, Ashraf SS, Helferich B, Yang X, Guha G, Bhakta D, Ciriolo MR, Aquilano K, Chen S, Halicka D, Mohammed SI, Azmi AS, Bilsland A, Keith WN, Jensen LD
Semin Cancer Biol 2015 Dec;35 Suppl(Suppl):S224-S243. Epub 2015 Jan 16 doi: 10.1016/j.semcancer.2015.01.001. PMID: 25600295Free PMC Article
Shahneh FZ, Baradaran B, Zamani F, Aghebati-Maleki L
Hum Antibodies 2013;22(1-2):15-9. doi: 10.3233/HAB-130267. PMID: 24284305
Albo D, Wang TN, Tuszynski GP
Curr Pharm Des 2004;10(1):27-37. doi: 10.2174/1381612043453522. PMID: 14754403

Prognosis

Mabeta P, Hull R, Dlamini Z
Genes (Basel) 2022 Jan 15;13(1) doi: 10.3390/genes13010152. PMID: 35052495Free PMC Article
Asokan S, Bandapalli OR
Adv Exp Med Biol 2021;1302:25-39. doi: 10.1007/978-3-030-62658-7_3. PMID: 34286439
Reuss AM, Groos D, Buchfelder M, Savaskan N
Int J Mol Sci 2021 May 24;22(11) doi: 10.3390/ijms22115518. PMID: 34073734Free PMC Article
March B, Faulkner S, Jobling P, Steigler A, Blatt A, Denham J, Hondermarck H
Nat Rev Urol 2020 Feb;17(2):119-130. Epub 2020 Jan 14 doi: 10.1038/s41585-019-0274-3. PMID: 31937919
Fagiani E, Christofori G
Cancer Lett 2013 Jan 1;328(1):18-26. Epub 2012 Aug 23 doi: 10.1016/j.canlet.2012.08.018. PMID: 22922303

Clinical prediction guides

March B, Faulkner S, Jobling P, Steigler A, Blatt A, Denham J, Hondermarck H
Nat Rev Urol 2020 Feb;17(2):119-130. Epub 2020 Jan 14 doi: 10.1038/s41585-019-0274-3. PMID: 31937919
Ribatti D, Vacca A
Cancer Treat Res 2016;169:51-61. doi: 10.1007/978-3-319-40320-5_5. PMID: 27696258
Zhang XH, Giuliano M, Trivedi MV, Schiff R, Osborne CK
Clin Cancer Res 2013 Dec 1;19(23):6389-97. doi: 10.1158/1078-0432.CCR-13-0838. PMID: 24298069Free PMC Article
Angelillo-Scherrer A
Circ Res 2012 Jan 20;110(2):356-69. doi: 10.1161/CIRCRESAHA.110.233403. PMID: 22267840
Naumov GN, Folkman J, Straume O, Akslen LA
APMIS 2008 Jul-Aug;116(7-8):569-85. doi: 10.1111/j.1600-0463.2008.01213.x. PMID: 18834403

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