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Benign Ovarian Clear Cell Tumor

MedGen UID:
307263
Concept ID:
C1511098
Neoplastic Process
Synonym: Benign Ovarian Clear Cell Neoplasm

Definition

A non-metastasizing neoplasm that arises from the ovary. It is characterized by a predominance of clear and hobnail benign epithelial cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Ovarian Clear Cell Tumor

Professional guidelines

PubMed

Ohya A, Fujinaga Y
Jpn J Radiol 2022 Dec;40(12):1213-1234. Epub 2022 Aug 2 doi: 10.1007/s11604-022-01321-x. PMID: 35916971Free PMC Article
Okamoto S, Ito K, Sasano H, Moriya T, Niikura H, Terada Y, Sato S, Okamura K, Yaegashi N
Tohoku J Exp Med 2005 May;206(1):31-40. doi: 10.1620/tjem.206.31. PMID: 15802873
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467

Recent clinical studies

Etiology

Collins KE, Wang X, Klymenko Y, Davis NB, Martinez MC, Zhang C, So K, Buechlein A, Rusch DB, Creighton CJ, Hawkins SM
Front Endocrinol (Lausanne) 2023;14:1162786. Epub 2023 Aug 9 doi: 10.3389/fendo.2023.1162786. PMID: 37621654Free PMC Article
Prat J
Best Pract Res Clin Obstet Gynaecol 2017 May;41:15-30. Epub 2016 Oct 3 doi: 10.1016/j.bpobgyn.2016.08.007. PMID: 28277307
Wilbur MA, Shih IM, Segars JH, Fader AN
Semin Reprod Med 2017 Jan;35(1):110-116. Epub 2017 Jan 3 doi: 10.1055/s-0036-1597120. PMID: 28049216
Kurman RJ, Shih IeM
Am J Pathol 2016 Apr;186(4):733-47. doi: 10.1016/j.ajpath.2015.11.011. PMID: 27012190Free PMC Article
Kurman RJ, Shih IeM
Am J Surg Pathol 2010 Mar;34(3):433-43. doi: 10.1097/PAS.0b013e3181cf3d79. PMID: 20154587Free PMC Article

Diagnosis

Buza N
Arch Pathol Lab Med 2019 Jan;143(1):47-64. doi: 10.5858/arpa.2018-0289-RA. PMID: 30785337
Prat J
Best Pract Res Clin Obstet Gynaecol 2017 May;41:15-30. Epub 2016 Oct 3 doi: 10.1016/j.bpobgyn.2016.08.007. PMID: 28277307
Wilbur MA, Shih IM, Segars JH, Fader AN
Semin Reprod Med 2017 Jan;35(1):110-116. Epub 2017 Jan 3 doi: 10.1055/s-0036-1597120. PMID: 28049216
Bennett JA, Oliva E
Clin Obstet Gynecol 2015 Mar;58(1):3-27. doi: 10.1097/GRF.0000000000000082. PMID: 25608250
Kobayashi H
Int J Clin Oncol 2009 Oct;14(5):378-82. Epub 2009 Oct 25 doi: 10.1007/s10147-009-0931-2. PMID: 19856043

Therapy

Gjorgoska M, Rizner TL
J Steroid Biochem Mol Biol 2024 May;239:106482. Epub 2024 Feb 17 doi: 10.1016/j.jsbmb.2024.106482. PMID: 38369034
Yao TT, Zhao SJ, Zhang B
BMC Womens Health 2023 Oct 27;23(1):559. doi: 10.1186/s12905-023-02695-4. PMID: 37891576Free PMC Article
Huo X, Yao L, Han X, Li W, Liu J, Zhou L, Gou Y, Yang K, Liu H
Arch Gynecol Obstet 2019 Mar;299(3):599-607. Epub 2019 Jan 4 doi: 10.1007/s00404-018-5020-1. PMID: 30607584
Kobayashi H
Int J Clin Oncol 2009 Oct;14(5):378-82. Epub 2009 Oct 25 doi: 10.1007/s10147-009-0931-2. PMID: 19856043
Van Gorp T, Amant F, Neven P, Vergote I, Moerman P
Best Pract Res Clin Obstet Gynaecol 2004 Apr;18(2):349-71. doi: 10.1016/j.bpobgyn.2003.03.001. PMID: 15157647

Prognosis

Collins KE, Wang X, Klymenko Y, Davis NB, Martinez MC, Zhang C, So K, Buechlein A, Rusch DB, Creighton CJ, Hawkins SM
Front Endocrinol (Lausanne) 2023;14:1162786. Epub 2023 Aug 9 doi: 10.3389/fendo.2023.1162786. PMID: 37621654Free PMC Article
Prat J
Best Pract Res Clin Obstet Gynaecol 2017 May;41:15-30. Epub 2016 Oct 3 doi: 10.1016/j.bpobgyn.2016.08.007. PMID: 28277307
Plewka D, Jakubiec-Bartnik B, Morek M, Bogunia E, Bienioszek M, Wolski H, Kotrych D, Dziekan K, Seremak-Mrozikiewicz A, Plewka A
Ginekol Pol 2015 Jul;86(7):525-30. doi: 10.17772/gp/57855. PMID: 26376531
Schuijer M, Berns EM
Hum Mutat 2003 Mar;21(3):285-91. doi: 10.1002/humu.10181. PMID: 12619114
Bale PM, Painter DM, Cohen D
Pathology 1975 Jul;7(3):209-18. doi: 10.3109/00313027509094411. PMID: 1196679

Clinical prediction guides

Collins KE, Wang X, Klymenko Y, Davis NB, Martinez MC, Zhang C, So K, Buechlein A, Rusch DB, Creighton CJ, Hawkins SM
Front Endocrinol (Lausanne) 2023;14:1162786. Epub 2023 Aug 9 doi: 10.3389/fendo.2023.1162786. PMID: 37621654Free PMC Article
Sensu S, Keser SH, Gurbuz Y, Barisik NO, Gul AE
Arch Iran Med 2021 Apr 1;24(4):301-305. doi: 10.34172/aim.2021.42. PMID: 34196190
Hosseini ES, Meryet-Figuiere M, Sabzalipoor H, Kashani HH, Nikzad H, Asemi Z
Mol Cancer 2017 Jun 21;16(1):107. doi: 10.1186/s12943-017-0671-2. PMID: 28637507Free PMC Article
Kobayashi H
Int J Clin Oncol 2009 Oct;14(5):378-82. Epub 2009 Oct 25 doi: 10.1007/s10147-009-0931-2. PMID: 19856043
Schuijer M, Berns EM
Hum Mutat 2003 Mar;21(3):285-91. doi: 10.1002/humu.10181. PMID: 12619114

Recent systematic reviews

Butler H, Saulat O, Guinn BA
Carcinogenesis 2022 Apr 25;43(3):183-189. doi: 10.1093/carcin/bgac012. PMID: 35104328Free PMC Article
Huo X, Yao L, Han X, Li W, Liu J, Zhou L, Gou Y, Yang K, Liu H
Arch Gynecol Obstet 2019 Mar;299(3):599-607. Epub 2019 Jan 4 doi: 10.1007/s00404-018-5020-1. PMID: 30607584
Heatley MK
Int J Gynecol Pathol 2012 Mar;31(2):111-5. doi: 10.1097/PGP.0b013e318226043b. PMID: 22317865

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